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Central nervous system lupus

MedGen UID:
156265
Concept ID:
C0752332
Disease or Syndrome
Synonyms: Central Nervous System Lupus; Central Nervous System Lupus Vasculitis; Central Nervous System Systemic Lupus Erythematosis; Lupus Vasculitis, Central Nervous System; Systemic Lupus Erythematosis, Central Nervous System
 
Monarch Initiative: MONDO:0043985

Definition

Inflammation that includes the brain, spinal cord and surrounding tissues secondary to systemic lupus erythematosus (SLE); it is associated with neurological and/or psychiatric features. [from NCI]

Professional guidelines

PubMed

Nozaki K, Silver RM, Stickler DE, Abou-Fayssal NG, Giglio P, Kamen DL, Daniel R, Judson MA
Am J Med Sci 2011 Nov;342(5):352-5. doi: 10.1097/MAJ.0b013e31822b7bb8. PMID: 21876428
Hughes GR
J Rheumatol 1980 May-Jun;7(3):405-11. PMID: 7401072
Sergent JS, Lockshin MD
Ann Intern Med 1974 Mar;80(3):413-4. doi: 10.7326/0003-4819-80-3-413_2. PMID: 4816188

Recent clinical studies

Etiology

Ota Y, Srinivasan A, Capizzano AA, Bapuraj JR, Kim J, Kurokawa R, Baba A, Moritani T
Radiographics 2022 Jan-Feb;42(1):212-232. doi: 10.1148/rg.210045. PMID: 34990324
Papachristos DA, Oon S, Hanly JG, Nikpour M
Semin Arthritis Rheum 2021 Feb;51(1):49-71. Epub 2020 Dec 17 doi: 10.1016/j.semarthrit.2020.12.004. PMID: 33360230
Liu T, Son M, Diamond B
Front Immunol 2020;11:1057. Epub 2020 May 27 doi: 10.3389/fimmu.2020.01057. PMID: 32536928Free PMC Article
Tunnicliffe DJ, Singh-Grewal D, Kim S, Craig JC, Tong A
Arthritis Care Res (Hoboken) 2015 Oct;67(10):1440-52. doi: 10.1002/acr.22591. PMID: 25778500
Bertsias GK, Ioannidis JP, Aringer M, Bollen E, Bombardieri S, Bruce IN, Cervera R, Dalakas M, Doria A, Hanly JG, Huizinga TW, Isenberg D, Kallenberg C, Piette JC, Schneider M, Scolding N, Smolen J, Stara A, Tassiulas I, Tektonidou M, Tincani A, van Buchem MA, van Vollenhoven R, Ward M, Gordon C, Boumpas DT
Ann Rheum Dis 2010 Dec;69(12):2074-82. Epub 2010 Aug 19 doi: 10.1136/ard.2010.130476. PMID: 20724309

Diagnosis

Ota Y, Srinivasan A, Capizzano AA, Bapuraj JR, Kim J, Kurokawa R, Baba A, Moritani T
Radiographics 2022 Jan-Feb;42(1):212-232. doi: 10.1148/rg.210045. PMID: 34990324
Carrión-Barberà I, Salman-Monte TC, Vílchez-Oya F, Monfort J
Autoimmun Rev 2021 Apr;20(4):102780. Epub 2021 Feb 18 doi: 10.1016/j.autrev.2021.102780. PMID: 33609799
Calle-Botero E, Abril A
Curr Rheumatol Rep 2020 Aug 26;22(10):71. doi: 10.1007/s11926-020-00937-0. PMID: 32845454
Schwartz N, Stock AD, Putterman C
Nat Rev Rheumatol 2019 Mar;15(3):137-152. doi: 10.1038/s41584-018-0156-8. PMID: 30659245Free PMC Article
Tunnicliffe DJ, Singh-Grewal D, Kim S, Craig JC, Tong A
Arthritis Care Res (Hoboken) 2015 Oct;67(10):1440-52. doi: 10.1002/acr.22591. PMID: 25778500

Therapy

Papachristos DA, Oon S, Hanly JG, Nikpour M
Semin Arthritis Rheum 2021 Feb;51(1):49-71. Epub 2020 Dec 17 doi: 10.1016/j.semarthrit.2020.12.004. PMID: 33360230
Fanouriakis A, Tziolos N, Bertsias G, Boumpas DT
Ann Rheum Dis 2021 Jan;80(1):14-25. Epub 2020 Oct 13 doi: 10.1136/annrheumdis-2020-218272. PMID: 33051219
Raciborska DD, Noyce AJ, Pyne D, Turner BP
Pract Neurol 2018 Feb;18(1):66-69. Epub 2017 Nov 2 doi: 10.1136/practneurol-2017-001756. PMID: 29097555
Ribeiro FM, Signorelli F
Lupus 2017 Apr;26(5):490-496. doi: 10.1177/0961203317691375. PMID: 28394236
Kamen DL, Zollars ES
Rheum Dis Clin North Am 2016 Feb;42(1):63-73, viii. Epub 2015 Oct 24 doi: 10.1016/j.rdc.2015.08.008. PMID: 26611551

Prognosis

Nikolopoulos D, Manolakou T, Polissidis A, Filia A, Bertsias G, Koutmani Y, Boumpas DT
Ann Rheum Dis 2023 May;82(5):646-657. Epub 2023 Mar 10 doi: 10.1136/ard-2022-223506. PMID: 36898766Free PMC Article
Fanouriakis A, Tziolos N, Bertsias G, Boumpas DT
Ann Rheum Dis 2021 Jan;80(1):14-25. Epub 2020 Oct 13 doi: 10.1136/annrheumdis-2020-218272. PMID: 33051219
Moore E, Huang MW, Putterman C
Curr Opin Rheumatol 2020 Mar;32(2):152-158. doi: 10.1097/BOR.0000000000000682. PMID: 31895125Free PMC Article
Schwartz N, Stock AD, Putterman C
Nat Rev Rheumatol 2019 Mar;15(3):137-152. doi: 10.1038/s41584-018-0156-8. PMID: 30659245Free PMC Article
Tunnicliffe DJ, Singh-Grewal D, Kim S, Craig JC, Tong A
Arthritis Care Res (Hoboken) 2015 Oct;67(10):1440-52. doi: 10.1002/acr.22591. PMID: 25778500

Clinical prediction guides

Nikolopoulos D, Manolakou T, Polissidis A, Filia A, Bertsias G, Koutmani Y, Boumpas DT
Ann Rheum Dis 2023 May;82(5):646-657. Epub 2023 Mar 10 doi: 10.1136/ard-2022-223506. PMID: 36898766Free PMC Article
Papachristos DA, Oon S, Hanly JG, Nikpour M
Semin Arthritis Rheum 2021 Feb;51(1):49-71. Epub 2020 Dec 17 doi: 10.1016/j.semarthrit.2020.12.004. PMID: 33360230
Moore E, Huang MW, Putterman C
Curr Opin Rheumatol 2020 Mar;32(2):152-158. doi: 10.1097/BOR.0000000000000682. PMID: 31895125Free PMC Article
Kamen DL, Zollars ES
Rheum Dis Clin North Am 2016 Feb;42(1):63-73, viii. Epub 2015 Oct 24 doi: 10.1016/j.rdc.2015.08.008. PMID: 26611551
Tunnicliffe DJ, Singh-Grewal D, Kim S, Craig JC, Tong A
Arthritis Care Res (Hoboken) 2015 Oct;67(10):1440-52. doi: 10.1002/acr.22591. PMID: 25778500

Recent systematic reviews

Liu Z, Cheng R, Liu Y
Front Immunol 2022;13:996662. Epub 2022 Sep 23 doi: 10.3389/fimmu.2022.996662. PMID: 36211347Free PMC Article
Parperis K, Kyriakou A, Voskarides K, Chatzittofis A
Semin Arthritis Rheum 2022 Jun;54:151997. Epub 2022 Mar 19 doi: 10.1016/j.semarthrit.2022.151997. PMID: 35344734
Papachristos DA, Oon S, Hanly JG, Nikpour M
Semin Arthritis Rheum 2021 Feb;51(1):49-71. Epub 2020 Dec 17 doi: 10.1016/j.semarthrit.2020.12.004. PMID: 33360230
Tunnicliffe DJ, Singh-Grewal D, Kim S, Craig JC, Tong A
Arthritis Care Res (Hoboken) 2015 Oct;67(10):1440-52. doi: 10.1002/acr.22591. PMID: 25778500
Chen CC, Lin KL, Chen CL, Wong AM, Huang JL
Lupus 2013 Dec;22(14):1484-8. Epub 2013 Oct 18 doi: 10.1177/0961203313509294. PMID: 24142583

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