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Perivascular cardiac fibrosis

MedGen UID:
1612197
•Concept ID:
C4531195
•
Finding
HPO: HP:0031328

Definition

A type of myocardial fibrosis characterized by excessive diffuse collagen accumulation concentrated in perivascular spaces. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPerivascular cardiac fibrosis

Professional guidelines

PubMed

Current challenges in the treatment of cardiac fibrosis: Recent insights into the sex-specific differences of glucose-lowering therapies on the diabetic heart: IUPHAR Review 33.
Sharma A, De Blasio M, Ritchie R
Br J Pharmacol 2023 Nov;180(22):2916-2933. Epub 2022 Mar 10 doi: 10.1111/bph.15820. PMID: 35174479Free PMC Article
Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis.
Sun Q, Baues M, Klinkhammer BM, Ehling J, Djudjaj S, Drude NI, Daniel C, Amann K, Kramann R, Kim H, Saez-Rodriguez J, Weiskirchen R, Onthank DC, Botnar RM, Kiessling F, Floege J, Lammers T, Boor P
Sci Transl Med 2019 Apr 3;11(486) doi: 10.1126/scitranslmed.aat4865. PMID: 30944168Free PMC Article
Evaluation of subclinical target organ damage for risk assessment and treatment in the hypertensive patients: left ventricular hypertrophy.
Agabiti-Rosei E, Muiesan ML, Salvetti M
J Am Soc Nephrol 2006 Apr;17(4 Suppl 2):S104-8. doi: 10.1681/ASN.2005121336. PMID: 16565230

Recent clinical studies

Etiology

Exposure to multiple ion beams, broadly representative of galactic cosmic rays, causes perivascular cardiac fibrosis in mature male rats.
Lenarczyk M, Kronenberg A, Mäder M, Komorowski R, Hopewell JW, Baker JE
PLoS One 2023;18(4):e0283877. Epub 2023 Apr 26 doi: 10.1371/journal.pone.0283877. PMID: 37099482Free PMC Article

Therapy

Exposure to multiple ion beams, broadly representative of galactic cosmic rays, causes perivascular cardiac fibrosis in mature male rats.
Lenarczyk M, Kronenberg A, Mäder M, Komorowski R, Hopewell JW, Baker JE
PLoS One 2023;18(4):e0283877. Epub 2023 Apr 26 doi: 10.1371/journal.pone.0283877. PMID: 37099482Free PMC Article

Supplemental Content

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    Clinical resources

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    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
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      Related literature resources in PubMed

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