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Posterior Subcapsular Cataract Grade 3

MedGen UID:
1614769
•Concept ID:
C4525733
•
Disease or Syndrome

Definition

A stage of posterior subcapsular cataract characterized by 50% of the posterior capsule obscured by opacity. (Modified LOCS II) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPosterior Subcapsular Cataract Grade 3

Professional guidelines

PubMed

Cataract in renal transplantation recipients with combination ciclosporin treatment.
Nishimoto K, Sasaki K, Yamamura T, Ishikawa I, Shinoda A
Lens Eye Toxic Res 1992;9(3-4):455-67. PMID: 1301797

Recent clinical studies

Etiology

Cataract and quality of life in patients with glaucoma.
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739
Myopia and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study.
Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555
The impact of cataract, cataract types, and cataract grades on vision-specific functioning using Rasch analysis.
Chew M, Chiang PP, Zheng Y, Lavanya R, Wu R, Saw SM, Wong TY, Lamoureux EL
Am J Ophthalmol 2012 Jul;154(1):29-38.e2. Epub 2012 Apr 26 doi: 10.1016/j.ajo.2012.01.033. PMID: 22541931
Lens retrodots and vacuoles and their associations with the prevalence and incidence of age-related cataract.
Tan AG, Mitchell P, Rochtchina E, Hong T, Cumming RG, Wang JJ
Eye (Lond) 2012 Apr;26(4):568-75. Epub 2011 Dec 23 doi: 10.1038/eye.2011.349. PMID: 22193877Free PMC Article
Posterior subcapsular and nuclear cataract after vitrectomy.
Hsuan JD, Brown NA, Bron AJ, Patel CK, Rosen PH
J Cataract Refract Surg 2001 Mar;27(3):437-44. doi: 10.1016/s0886-3350(00)00585-x. PMID: 11255058

Diagnosis

Age-related cataract - Prevalence, epidemiological pattern and emerging risk factors in a cross-sectional study from Central India.
Sarkar D, Sharma R, Singh P, Verma V, Karkhur S, Verma S, Soni D, Sharma B
Indian J Ophthalmol 2023 May;71(5):1905-1912. doi: 10.4103/ijo.IJO_2020_22. PMID: 37203054Free PMC Article
Myopia and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study.
Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555
Pseudoexfoliation syndrome and the long-term incidence of cataract and cataract surgery: the blue mountains eye study.
Kanthan GL, Mitchell P, Burlutsky G, Rochtchina E, Wang JJ
Am J Ophthalmol 2013 Jan;155(1):83-88.e1. Epub 2012 Oct 2 doi: 10.1016/j.ajo.2012.07.002. PMID: 23036566
Use of inhaled and oral corticosteroids and the long-term risk of cataract.
Wang JJ, Rochtchina E, Tan AG, Cumming RG, Leeder SR, Mitchell P
Ophthalmology 2009 Apr;116(4):652-7. Epub 2009 Feb 25 doi: 10.1016/j.ophtha.2008.12.001. PMID: 19243828
Posterior subcapsular and nuclear cataract after vitrectomy.
Hsuan JD, Brown NA, Bron AJ, Patel CK, Rosen PH
J Cataract Refract Surg 2001 Mar;27(3):437-44. doi: 10.1016/s0886-3350(00)00585-x. PMID: 11255058

Therapy

Wholegrain and legume consumption and the 5-year incidence of age-related cataract in the Blue Mountains Eye Study.
Tan AG, Flood VM, Kifley A, Russell J, Cumming RG, Mitchell P, Wang JJ
Br J Nutr 2020 Aug 14;124(3):306-315. Epub 2020 Mar 19 doi: 10.1017/S000711452000104X. PMID: 32189601
Evaluating the associations between obesity and age-related cataract: a Mendelian randomization study.
Tan AG, Kifley A, Flood VM, Holliday EG, Scott RJ, Cumming RG, Mitchell P, Wang JJ
Am J Clin Nutr 2019 Oct 1;110(4):969-976. doi: 10.1093/ajcn/nqz167. PMID: 31401654
Use of inhaled and oral corticosteroids and the long-term risk of cataract.
Wang JJ, Rochtchina E, Tan AG, Cumming RG, Leeder SR, Mitchell P
Ophthalmology 2009 Apr;116(4):652-7. Epub 2009 Feb 25 doi: 10.1016/j.ophtha.2008.12.001. PMID: 19243828
Plasma antioxidant vitamins and carotenoids and age-related cataract.
Gale CR, Hall NF, Phillips DI, Martyn CN
Ophthalmology 2001 Nov;108(11):1992-8. doi: 10.1016/s0161-6420(01)00833-8. PMID: 11713067
Posterior subcapsular and nuclear cataract after vitrectomy.
Hsuan JD, Brown NA, Bron AJ, Patel CK, Rosen PH
J Cataract Refract Surg 2001 Mar;27(3):437-44. doi: 10.1016/s0886-3350(00)00585-x. PMID: 11255058

Prognosis

Wholegrain and legume consumption and the 5-year incidence of age-related cataract in the Blue Mountains Eye Study.
Tan AG, Flood VM, Kifley A, Russell J, Cumming RG, Mitchell P, Wang JJ
Br J Nutr 2020 Aug 14;124(3):306-315. Epub 2020 Mar 19 doi: 10.1017/S000711452000104X. PMID: 32189601
Myopia and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study.
Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555
Lens retrodots and vacuoles and their associations with the prevalence and incidence of age-related cataract.
Tan AG, Mitchell P, Rochtchina E, Hong T, Cumming RG, Wang JJ
Eye (Lond) 2012 Apr;26(4):568-75. Epub 2011 Dec 23 doi: 10.1038/eye.2011.349. PMID: 22193877Free PMC Article
Myopia and incident cataract and cataract surgery: the blue mountains eye study.
Younan C, Mitchell P, Cumming RG, Rochtchina E, Wang JJ
Invest Ophthalmol Vis Sci 2002 Dec;43(12):3625-32. PMID: 12454028
Posterior subcapsular and nuclear cataract after vitrectomy.
Hsuan JD, Brown NA, Bron AJ, Patel CK, Rosen PH
J Cataract Refract Surg 2001 Mar;27(3):437-44. doi: 10.1016/s0886-3350(00)00585-x. PMID: 11255058

Clinical prediction guides

Long-term Outcomes of Cataract Surgery in Patients With Chronic Ocular Graft-Versus-Host Disease.
Bae SS, Iovieno A, Yeung SN
Cornea 2022 May 1;41(5):587-592. doi: 10.1097/ICO.0000000000002779. PMID: 34050071
Effect of Cataract Grade according to Wide-Field Fundus Images on Measurement of Macular Thickness in Cataract Patients.
Kim M, Eom Y, Song JS, Kim HM
Korean J Ophthalmol 2018 Jun;32(3):172-181. Epub 2018 May 15 doi: 10.3341/kjo.2017.0067. PMID: 29770639Free PMC Article
Cataract and quality of life in patients with glaucoma.
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739
Subjective quality of vision before and after cataract surgery.
Skiadaresi E, McAlinden C, Pesudovs K, Polizzi S, Khadka J, Ravalico G
Arch Ophthalmol 2012 Nov;130(11):1377-82. doi: 10.1001/archophthalmol.2012.1603. PMID: 23143439
The impact of cataract, cataract types, and cataract grades on vision-specific functioning using Rasch analysis.
Chew M, Chiang PP, Zheng Y, Lavanya R, Wu R, Saw SM, Wong TY, Lamoureux EL
Am J Ophthalmol 2012 Jul;154(1):29-38.e2. Epub 2012 Apr 26 doi: 10.1016/j.ajo.2012.01.033. PMID: 22541931

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