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Motor aphasia

MedGen UID:
1622
Concept ID:
C0003550
Mental or Behavioral Dysfunction
Synonyms: Agrammatic Broca Aphasia; Agrammatic Broca Aphasias; Agrammatic Broca's Aphasia; Agrammatic Broca's Aphasias; Agrammatic Brocas Aphasia; Agrammatism; Aphasia Syndrome, Verbal; Aphasia Syndromes, Verbal; Aphasia, Agrammatic Broca; Aphasia, Agrammatic Broca's; Aphasia, Broca; Aphasia, Frontocortical; Aphasia, Motor; Aphasia, Nonfluent; Aphasias, Agrammatic Broca; Aphasias, Agrammatic Broca's; Aphasias, Broca; Aphasias, Frontocortical; Broca Aphasia; Broca Aphasia, Agrammatic; Broca Aphasias; Broca Aphasias, Agrammatic; Broca Dysphasia; Broca's Aphasia, Agrammatic; Broca's Aphasias, Agrammatic; Broca's Dysphasia; Dysphasia, Broca; Dysphasia, Broca's; Dysphasia, Brocas; Frontocortical Aphasia; Frontocortical Aphasias; Motor Aphasia; Nonfluent Aphasia; Syndrome, Verbal Aphasia; Syndromes, Verbal Aphasia; Verbal Aphasia Syndrome; Verbal Aphasia Syndromes
SNOMED CT: Broca dysphasia (229654003); Broca's dysphasia (229654003); Broca's aphasia (229654003); Frontocortical aphasia (328681008); Motor aphasia (328681008)

Definition

Aphasia characterized by impairment of expressive language due to injury to the motor association cortex in the frontal lobe. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Zhou BY, Zhu CF, Wei P, Zhao HY, Wang C, Cheng L, Liu L, Wu AQ
Zhen Ci Yan Jiu 2023 Nov 25;48(11):1175-1182. doi: 10.13702/j.1000-0607.20221182. PMID: 37984916
Harris JM, Gall C, Thompson JC, Richardson AM, Neary D, du Plessis D, Pal P, Mann DM, Snowden JS, Jones M
Neurology 2013 May 14;80(20):1881-7. Epub 2013 Apr 17 doi: 10.1212/WNL.0b013e318292a342. PMID: 23596080
Raymer AM
Front Biosci 2003 Sep 1;8:s845-51. doi: 10.2741/1142. PMID: 12957880

Recent clinical studies

Etiology

Li B, Deng S, Zhuo B, Sang B, Chen J, Zhang M, Tian G, Zhang L, Du Y, Zheng P, Yue G, Meng Z
JAMA Netw Open 2024 Jan 2;7(1):e2352580. doi: 10.1001/jamanetworkopen.2023.52580. PMID: 38252438Free PMC Article
Deng S, Sang B, Li B, Lu H, Zhang L, Tian G, Hao T, Zhang Y, Shi L, Sun K, Ba T, Li F, Kong Y, Qin M, Zhang J, Zhao X, Meng Z
Trials 2022 Jun 30;23(1):540. doi: 10.1186/s13063-022-06280-2. PMID: 35773693Free PMC Article
Chen Q, Shen W, Sun H, Shen D, Cai X, Ke J, Zhang L, Fang Q
NeuroRehabilitation 2021;49(1):103-117. doi: 10.3233/NRE-210125. PMID: 34180428
Pincherle A, Rossi F, Jöhr J, Dunet V, Ryvlin P, Oddo M, Schiff N, Diserens K
J Neurol 2021 Jan;268(1):178-188. Epub 2020 Aug 4 doi: 10.1007/s00415-020-10125-w. PMID: 32754829Free PMC Article
Madhusoodanan S, Reddy V, Mohan S
Curr Drug Saf 2017;12(3):201-204. doi: 10.2174/1574886312666170601092949. PMID: 28571548

Diagnosis

Li B, Deng S, Zhuo B, Sang B, Chen J, Zhang M, Tian G, Zhang L, Du Y, Zheng P, Yue G, Meng Z
JAMA Netw Open 2024 Jan 2;7(1):e2352580. doi: 10.1001/jamanetworkopen.2023.52580. PMID: 38252438Free PMC Article
Gordon JK, Clough S
J Speech Lang Hear Res 2022 Apr 4;65(4):1521-1542. Epub 2022 Mar 10 doi: 10.1044/2021_JSLHR-21-00484. PMID: 35271379
Gonzalez R, Rojas M, Ardila A
Int J Lang Commun Disord 2020 Nov;55(6):875-883. Epub 2020 Jul 31 doi: 10.1111/1460-6984.12566. PMID: 32735061
Taubner RW, Raymer AM, Heilman KM
Brain Lang 1999 Nov;70(2):240-61. doi: 10.1006/brln.1999.2157. PMID: 10550229
Kertesz A
Acta Neurochir Suppl (Wien) 1993;56:52-8. doi: 10.1007/978-3-7091-9239-9_9. PMID: 8498201

Therapy

Li B, Deng S, Zhuo B, Sang B, Chen J, Zhang M, Tian G, Zhang L, Du Y, Zheng P, Yue G, Meng Z
JAMA Netw Open 2024 Jan 2;7(1):e2352580. doi: 10.1001/jamanetworkopen.2023.52580. PMID: 38252438Free PMC Article
Deng S, Sang B, Li B, Lu H, Zhang L, Tian G, Hao T, Zhang Y, Shi L, Sun K, Ba T, Li F, Kong Y, Qin M, Zhang J, Zhao X, Meng Z
Trials 2022 Jun 30;23(1):540. doi: 10.1186/s13063-022-06280-2. PMID: 35773693Free PMC Article
Chen Q, Shen W, Sun H, Shen D, Cai X, Ke J, Zhang L, Fang Q
NeuroRehabilitation 2021;49(1):103-117. doi: 10.3233/NRE-210125. PMID: 34180428
Madhusoodanan S, Reddy V, Mohan S
Curr Drug Saf 2017;12(3):201-204. doi: 10.2174/1574886312666170601092949. PMID: 28571548
Hadano K, Nakamura H, Hamanaka T
Cortex 1998 Feb;34(1):67-82. doi: 10.1016/s0010-9452(08)70737-8. PMID: 9533994

Prognosis

Dong LL, Liu CY, Mao CH, Chu SS, Li J, Huang XY, Gao J
Chin Med Sci J 2020 Sep 30;35(3):207-214. doi: 10.24920/003669. PMID: 32972498
André C
Rev Neurol (Paris) 2020 Mar;176(3):189-193. Epub 2019 Sep 11 doi: 10.1016/j.neurol.2019.06.010. PMID: 31521397
Hu P, Mao Z, Liu C, Hu X, Kang H, Zhou F
J Dermatol 2018 Jun;45(6):723-726. Epub 2018 Mar 8 doi: 10.1111/1346-8138.14280. PMID: 29516548Free PMC Article
Choi HH, Ha EJ, Cho WS, Kang HS, Kim JE
World Neurosurg 2017 Dec;108:738-747. Epub 2017 Sep 23 doi: 10.1016/j.wneu.2017.09.096. PMID: 28951267
Kumral E, Ozdemirkiran T, Alper Y
Neurology 2004 Dec 28;63(12):2429-32. doi: 10.1212/01.wnl.0000147261.22630.f8. PMID: 15623721

Clinical prediction guides

Li B, Deng S, Zhuo B, Sang B, Chen J, Zhang M, Tian G, Zhang L, Du Y, Zheng P, Yue G, Meng Z
JAMA Netw Open 2024 Jan 2;7(1):e2352580. doi: 10.1001/jamanetworkopen.2023.52580. PMID: 38252438Free PMC Article
Pincherle A, Rossi F, Jöhr J, Dunet V, Ryvlin P, Oddo M, Schiff N, Diserens K
J Neurol 2021 Jan;268(1):178-188. Epub 2020 Aug 4 doi: 10.1007/s00415-020-10125-w. PMID: 32754829Free PMC Article
Gonzalez R, Rojas M, Ardila A
Int J Lang Commun Disord 2020 Nov;55(6):875-883. Epub 2020 Jul 31 doi: 10.1111/1460-6984.12566. PMID: 32735061
Madhusoodanan S, Reddy V, Mohan S
Curr Drug Saf 2017;12(3):201-204. doi: 10.2174/1574886312666170601092949. PMID: 28571548
Wu Q, Hu X, Wen X, Li F, Fu W
Technol Health Care 2016 Apr 29;24 Suppl 2:S691-6. doi: 10.3233/THC-161197. PMID: 27177100

Recent systematic reviews

Fu QW, Liu M, Zhang LZ, Yang H, Zhang LQ, Yang SS, Xie Y, Wan XX, Tang Y, Zhang QX
Chin J Integr Med 2022 Aug;28(8):743-752. Epub 2022 Jul 30 doi: 10.1007/s11655-022-3722-5. PMID: 35907173
Kim WJ, Rosselin C, Amatya B, Hafezi P, Khan F
J Rehabil Med 2020 Feb 7;52(2) doi: 10.2340/16501977-2637. PMID: 31922207

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