Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Nuclear Cataract Grade 2

MedGen UID:: 1622334
•Concept ID:: C4525724
•: Disease or Syndrome

Definition

A stage of nuclear sclerotic cataract marked by moderate yellowing and sclerosis of the lens nucleus. (Modified LOCS II) [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVNuclear Cataract Grade 2

Abnormality of the eye
- Abnormal eye morphology
  - Abnormal anterior eye segment morphology
    - Abnormal lens morphology
      - Cataract
        Nuclear sclerotic cataract
        Nuclear Cataract Grade 2

Professional guidelines

PubMed

Selinexor for the treatment of recurrent or metastatic salivary gland tumors: Results from the GEMS-001 clinical trial.

Hernando-Calvo A, Malone E, Day D, Prawira A, Weinreb I, Yang SYC, Wong H, Rodriguez A, Jennings S, Eliason A, Wang L, Spreafico A, Siu LL, Hansen AR
Cancer Med 2023 Oct;12(20):20299-20310. Epub 2023 Oct 11 doi: 10.1002/cam4.6589. PMID: 37818869 Free PMC Article

Management of Severely Subluxated Cataracts Using Femtosecond Laser-Assisted Cataract Surgery.

Chee SP, Wong MH, Jap A
Am J Ophthalmol 2017 Jan;173:7-15. Epub 2016 Sep 23 doi: 10.1016/j.ajo.2016.09.021. PMID: 27670621

See all (2)

Recent clinical studies

Etiology

Prevalence of Refractive Error in Vientiane Province, Lao People's Democratic Republic.

Patel C, Tan Y, Nygaard S, Guo B, Carrillo C, Burgess J, Souksamone K, Nouansavanh KO, Casson R
Ophthalmic Epidemiol 2023 Feb;30(1):57-65. Epub 2022 Feb 3 doi: 10.1080/09286586.2022.2028294. PMID: 35112939

Eye disease and mortality, cognition, disease, and modifiable risk factors: an umbrella review of meta-analyses of observational studies.

Trott M, Smith L, Veronese N, Pizzol D, Barnett Y, Gorely T, Pardhan S
Eye (Lond) 2022 Feb;36(2):369-378. Epub 2021 Jul 16 doi: 10.1038/s41433-021-01684-x. PMID: 34272511 Free PMC Article

Cortical Cataract and Refractive Error.

Michael R, Pareja-Aricò L, Rauscher FG, Barraquer RI
Ophthalmic Res 2019;62(3):157-165. Epub 2019 Mar 28 doi: 10.1159/000496865. PMID: 30921809

Exome Array Analysis of Nuclear Lens Opacity.

Loomis SJ, Klein AP, Lee KE, Chen F, Bomotti S, Truitt B, Iyengar SK, Klein R, Klein BEK, Duggal P
Ophthalmic Epidemiol 2018 Jun;25(3):215-219. Epub 2017 Nov 28 doi: 10.1080/09286586.2017.1406122. PMID: 29182452 Free PMC Article

The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.

Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY
Arch Ophthalmol 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035. PMID: 8512486

See all (283)

Diagnosis

AI-based diagnosis of nuclear cataract from slit-lamp videos.

Shimizu E, Tanji M, Nakayama S, Ishikawa T, Agata N, Yokoiwa R, Nishimura H, Khemlani RJ, Sato S, Hanyuda A, Sato Y
Sci Rep 2023 Dec 12;13(1):22046. doi: 10.1038/s41598-023-49563-7. PMID: 38086904 Free PMC Article

Cataract quantification using swept-source optical coherence tomography.

Brás JEG, Sickenberger W, Hirnschall N, Findl O
J Cataract Refract Surg 2018 Dec;44(12):1478-1481. Epub 2018 Nov 2 doi: 10.1016/j.jcrs.2018.08.009. PMID: 30392762

Exome Array Analysis of Nuclear Lens Opacity.

Objective assessment of nuclear cataract: comparison of double-pass and Scheimpflug systems.

Lim SA, Hwang J, Hwang KY, Chung SH
J Cataract Refract Surg 2014 May;40(5):716-21. doi: 10.1016/j.jcrs.2013.10.032. PMID: 24767907

The prevalence of cataract in a population with and without type 2 diabetes mellitus.

Olafsdottir E, Andersson DK, Stefánsson E
Acta Ophthalmol 2012 Jun;90(4):334-40. Epub 2011 Dec 16 doi: 10.1111/j.1755-3768.2011.02326.x. PMID: 22176834

See all (123)

Therapy

Selinexor for the treatment of recurrent or metastatic salivary gland tumors: Results from the GEMS-001 clinical trial.

Comparative study of FLACS vs conventional phacoemulsification for complex cataracts in vitrectomized eyes.

Cai L, Ma D, Xu X, Han X, Qiu X, Lu Y, Yang J
J Cataract Refract Surg 2022 Dec 1;48(12):1381-1387. doi: 10.1097/j.jcrs.0000000000000998. PMID: 36449671

Ultrasound energy consumption and macular changes with manual and femtolaser-assisted high-fluidics cataract surgery: a prospective randomized comparison.

Menapace R, Schartmüller D, Röggla V, Reiter GS, Leydolt C, Schwarzenbacher L
Acta Ophthalmol 2022 Mar;100(2):e414-e422. Epub 2021 Sep 20 doi: 10.1111/aos.14983. PMID: 34543523 Free PMC Article

Eye disease and mortality, cognition, disease, and modifiable risk factors: an umbrella review of meta-analyses of observational studies.

Trott M, Smith L, Veronese N, Pizzol D, Barnett Y, Gorely T, Pardhan S
Eye (Lond) 2022 Feb;36(2):369-378. Epub 2021 Jul 16 doi: 10.1038/s41433-021-01684-x. PMID: 34272511 Free PMC Article

Wholegrain and legume consumption and the 5-year incidence of age-related cataract in the Blue Mountains Eye Study.

Tan AG, Flood VM, Kifley A, Russell J, Cumming RG, Mitchell P, Wang JJ
Br J Nutr 2020 Aug 14;124(3):306-315. Epub 2020 Mar 19 doi: 10.1017/S000711452000104X. PMID: 32189601

See all (151)

Prognosis

Eye disease and mortality, cognition, disease, and modifiable risk factors: an umbrella review of meta-analyses of observational studies.

Trott M, Smith L, Veronese N, Pizzol D, Barnett Y, Gorely T, Pardhan S
Eye (Lond) 2022 Feb;36(2):369-378. Epub 2021 Jul 16 doi: 10.1038/s41433-021-01684-x. PMID: 34272511 Free PMC Article

Wholegrain and legume consumption and the 5-year incidence of age-related cataract in the Blue Mountains Eye Study.

Tan AG, Flood VM, Kifley A, Russell J, Cumming RG, Mitchell P, Wang JJ
Br J Nutr 2020 Aug 14;124(3):306-315. Epub 2020 Mar 19 doi: 10.1017/S000711452000104X. PMID: 32189601

Exome Array Analysis of Nuclear Lens Opacity.

Objective assessment of nuclear cataract: comparison of double-pass and Scheimpflug systems.

Lim SA, Hwang J, Hwang KY, Chung SH
J Cataract Refract Surg 2014 May;40(5):716-21. doi: 10.1016/j.jcrs.2013.10.032. PMID: 24767907

Myopia and the long-term incidence of cataract and cataract surgery: the Blue Mountains Eye Study.

Kanthan GL, Mitchell P, Rochtchina E, Cumming RG, Wang JJ
Clin Exp Ophthalmol 2014 May-Jun;42(4):347-53. Epub 2013 Oct 11 doi: 10.1111/ceo.12206. PMID: 24024555

See all (106)

Clinical prediction guides

Eye disease and mortality, cognition, disease, and modifiable risk factors: an umbrella review of meta-analyses of observational studies.

Trott M, Smith L, Veronese N, Pizzol D, Barnett Y, Gorely T, Pardhan S
Eye (Lond) 2022 Feb;36(2):369-378. Epub 2021 Jul 16 doi: 10.1038/s41433-021-01684-x. PMID: 34272511 Free PMC Article

Cataract and quality of life in patients with glaucoma.

Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739

Objective assessment of nuclear cataract: comparison of double-pass and Scheimpflug systems.

Lim SA, Hwang J, Hwang KY, Chung SH
J Cataract Refract Surg 2014 May;40(5):716-21. doi: 10.1016/j.jcrs.2013.10.032. PMID: 24767907

The prevalence of cataract in a population with and without type 2 diabetes mellitus.

Olafsdottir E, Andersson DK, Stefánsson E
Acta Ophthalmol 2012 Jun;90(4):334-40. Epub 2011 Dec 16 doi: 10.1111/j.1755-3768.2011.02326.x. PMID: 22176834

The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.

Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY
Arch Ophthalmol 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035. PMID: 8512486

See all (130)

MedGen

National Center for Biotechnology Information

Send to:

Nuclear Cataract Grade 2

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity