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Penetrating aortic ulcer

MedGen UID:
1630969
Concept ID:
C4049312
Disease or Syndrome
Synonyms: Aortic Penetrating Ulcer; Aortic Penetrating Ulcers; Aortic Ulcer, Penetrating; Atherosclerotic Ulcer, Penetrating; Penetrating Aortic Ulcer; Penetrating Aortic Ulcers; Penetrating Atherosclerotic Ulcer; Penetrating Atherosclerotic Ulcers; Penetrating Ulcer; Penetrating Ulcer Aorta; Penetrating Ulcer Aortas; Penetrating Ulcer, Aortic; Penetrating Ulcers; Ulcer, Aortic Penetrating; Ulcer, Penetrating; Ulcer, Penetrating Aortic; Ulcer, Penetrating Atherosclerotic
 
HPO: HP:0031648

Definition

A focal defect in the elastic lamina of the aortic wall that leads to localized medial disruption and potential rupture. [from HPO]

Professional guidelines

PubMed

Shao T, Bornak A, Kang N
Vascular 2023 Dec;31(6):1086-1093. Epub 2022 May 16 doi: 10.1177/17085381221102785. PMID: 35578772
Sorber R, Hicks CW
Curr Cardiol Rep 2022 Mar;24(3):209-216. Epub 2022 Jan 14 doi: 10.1007/s11886-022-01642-3. PMID: 35029783Free PMC Article
Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, Evangelista A, Falk V, Frank H, Gaemperli O, Grabenwöger M, Haverich A, Iung B, Manolis AJ, Meijboom F, Nienaber CA, Roffi M, Rousseau H, Sechtem U, Sirnes PA, Allmen RS, Vrints CJ; ESC Committee for Practice Guidelines
Eur Heart J 2014 Nov 1;35(41):2873-926. Epub 2014 Aug 29 doi: 10.1093/eurheartj/ehu281. PMID: 25173340

Recent clinical studies

Etiology

Shao T, Bornak A, Kang N
Vascular 2023 Dec;31(6):1086-1093. Epub 2022 May 16 doi: 10.1177/17085381221102785. PMID: 35578772
Sorber R, Hicks CW
Curr Cardiol Rep 2022 Mar;24(3):209-216. Epub 2022 Jan 14 doi: 10.1007/s11886-022-01642-3. PMID: 35029783Free PMC Article
Evangelista A, Moral S
Curr Opin Cardiol 2020 Nov;35(6):620-626. doi: 10.1097/HCO.0000000000000782. PMID: 32925190
Strayer RJ
Emerg Med Clin North Am 2017 Nov;35(4):713-725. doi: 10.1016/j.emc.2017.06.002. PMID: 28987425
Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, Evangelista A, Falk V, Frank H, Gaemperli O, Grabenwöger M, Haverich A, Iung B, Manolis AJ, Meijboom F, Nienaber CA, Roffi M, Rousseau H, Sechtem U, Sirnes PA, Allmen RS, Vrints CJ; ESC Committee for Practice Guidelines
Eur Heart J 2014 Nov 1;35(41):2873-926. Epub 2014 Aug 29 doi: 10.1093/eurheartj/ehu281. PMID: 25173340

Diagnosis

Sorber R, Hicks CW
Curr Cardiol Rep 2022 Mar;24(3):209-216. Epub 2022 Jan 14 doi: 10.1007/s11886-022-01642-3. PMID: 35029783Free PMC Article
Rogers RK, Reece TB, Bonaca MP, Hess CN
Cardiol Clin 2021 Nov;39(4):495-503. doi: 10.1016/j.ccl.2021.06.002. PMID: 34686262
Evangelista A, Moral S
Curr Opin Cardiol 2020 Nov;35(6):620-626. doi: 10.1097/HCO.0000000000000782. PMID: 32925190
Strayer RJ
Emerg Med Clin North Am 2017 Nov;35(4):713-725. doi: 10.1016/j.emc.2017.06.002. PMID: 28987425
Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, Evangelista A, Falk V, Frank H, Gaemperli O, Grabenwöger M, Haverich A, Iung B, Manolis AJ, Meijboom F, Nienaber CA, Roffi M, Rousseau H, Sechtem U, Sirnes PA, Allmen RS, Vrints CJ; ESC Committee for Practice Guidelines
Eur Heart J 2014 Nov 1;35(41):2873-926. Epub 2014 Aug 29 doi: 10.1093/eurheartj/ehu281. PMID: 25173340

Therapy

Wang B, Qiu C, Yu X, He Y, Chen T, Lin R, Wang X, Pan J, Wang X, Zhang H, Wu Z
Vasc Endovascular Surg 2023 Nov;57(8):838-847. Epub 2023 Jun 2 doi: 10.1177/15385744231180678. PMID: 37267067
Cooper MA, Shahid Z, Upchurch GR Jr
Adv Surg 2022 Sep;56(1):129-150. doi: 10.1016/j.yasu.2022.02.005. PMID: 36096564
Rogers RK, Reece TB, Bonaca MP, Hess CN
Cardiol Clin 2021 Nov;39(4):495-503. doi: 10.1016/j.ccl.2021.06.002. PMID: 34686262
Nazerian P, Mueller C, Soeiro AM, Leidel BA, Salvadeo SAT, Giachino F, Vanni S, Grimm K, Oliveira MT Jr, Pivetta E, Lupia E, Grifoni S, Morello F; ADvISED Investigators
Circulation 2018 Jan 16;137(3):250-258. Epub 2017 Oct 13 doi: 10.1161/CIRCULATIONAHA.117.029457. PMID: 29030346
Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, Evangelista A, Falk V, Frank H, Gaemperli O, Grabenwöger M, Haverich A, Iung B, Manolis AJ, Meijboom F, Nienaber CA, Roffi M, Rousseau H, Sechtem U, Sirnes PA, Allmen RS, Vrints CJ; ESC Committee for Practice Guidelines
Eur Heart J 2014 Nov 1;35(41):2873-926. Epub 2014 Aug 29 doi: 10.1093/eurheartj/ehu281. PMID: 25173340

Prognosis

Vacirca A, Dias Neto M, Baghbani-Oskouei A, Huang Y, Tenorio ER, Estrera A, Oderich GS
Ann Vasc Surg 2023 Aug;94:14-21. Epub 2022 Oct 26 doi: 10.1016/j.avsg.2022.09.041. PMID: 36309166
Shao T, Bornak A, Kang N
Vascular 2023 Dec;31(6):1086-1093. Epub 2022 May 16 doi: 10.1177/17085381221102785. PMID: 35578772
Evangelista A, Moral S
Curr Opin Cardiol 2020 Nov;35(6):620-626. doi: 10.1097/HCO.0000000000000782. PMID: 32925190
Nazerian P, Mueller C, Soeiro AM, Leidel BA, Salvadeo SAT, Giachino F, Vanni S, Grimm K, Oliveira MT Jr, Pivetta E, Lupia E, Grifoni S, Morello F; ADvISED Investigators
Circulation 2018 Jan 16;137(3):250-258. Epub 2017 Oct 13 doi: 10.1161/CIRCULATIONAHA.117.029457. PMID: 29030346
D'Annoville T, Ozdemir BA, Alric P, Marty-Ané CH, Canaud L
Ann Thorac Surg 2016 Jun;101(6):2272-8. Epub 2016 Mar 22 doi: 10.1016/j.athoracsur.2015.12.036. PMID: 27012584

Clinical prediction guides

Piazza M, Squizzato F, Porcellato L, Casali E, Grego F, Antonello M
Semin Thorac Cardiovasc Surg 2024 Spring;36(1):1-10. Epub 2022 Aug 3 doi: 10.1053/j.semtcvs.2022.07.009. PMID: 35931348
Bianchini Massoni C, Ancetti S, Perini P, Spath P, D'Ospina RM, Gallitto E, Faggioli GL, Freyrie A, Gargiulo M
Ann Vasc Surg 2023 Jan;88:327-336. Epub 2022 Jul 31 doi: 10.1016/j.avsg.2022.06.101. PMID: 35921977
Nazerian P, Mueller C, Soeiro AM, Leidel BA, Salvadeo SAT, Giachino F, Vanni S, Grimm K, Oliveira MT Jr, Pivetta E, Lupia E, Grifoni S, Morello F; ADvISED Investigators
Circulation 2018 Jan 16;137(3):250-258. Epub 2017 Oct 13 doi: 10.1161/CIRCULATIONAHA.117.029457. PMID: 29030346
El Hassani I, Van Damme H, Creemers E, Boesmans E, Defraigne JO
Acta Chir Belg 2017 Feb;117(1):1-7. Epub 2016 Sep 3 doi: 10.1080/00015458.2016.1212566. PMID: 27593515
D'Annoville T, Ozdemir BA, Alric P, Marty-Ané CH, Canaud L
Ann Thorac Surg 2016 Jun;101(6):2272-8. Epub 2016 Mar 22 doi: 10.1016/j.athoracsur.2015.12.036. PMID: 27012584

Recent systematic reviews

Wang B, Qiu C, Yu X, He Y, Chen T, Lin R, Wang X, Pan J, Wang X, Zhang H, Wu Z
Vasc Endovascular Surg 2023 Nov;57(8):838-847. Epub 2023 Jun 2 doi: 10.1177/15385744231180678. PMID: 37267067
Pandey G, Sharma P
Vasc Endovascular Surg 2021 Oct;55(7):730-740. Epub 2021 May 28 doi: 10.1177/15385744211017110. PMID: 34044670
Spanos K, Nana P, Behrendt CA, Kouvelos G, Panuccio G, Heidemann F, Matsagkas M, Debus ES, Giannoukas A, Kölbel T
J Endovasc Ther 2021 Apr;28(2):323-331. Epub 2021 Jan 13 doi: 10.1177/1526602820987808. PMID: 33435805
Watanabe H, Horita N, Shibata Y, Minegishi S, Ota E, Kaneko T
Sci Rep 2016 May 27;6:26893. doi: 10.1038/srep26893. PMID: 27230962Free PMC Article
Georgiadis GS, Antoniou GA, Georgakarakos EI, Nikolopoulos ES, Papanas N, Trellopoulos G, Iatrou C, Papadopoulou MZ, Lazarides MK
J Vasc Interv Radiol 2013 Oct;24(10):1437-49.e3. Epub 2013 Aug 7 doi: 10.1016/j.jvir.2013.05.067. PMID: 23932417

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