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Aortopulmonary collateral arteries

MedGen UID:
1633176
Concept ID:
C4703564
Anatomical Abnormality
HPO: HP:0031834

Definition

Small ectopic arteries or arterial branches that connect the aorta, aortic branches and/or subclavian artery regions directly to the lung parenchyma, usually seen in conjunction with pulmonary atresia, ventricular septal defect (VSD) and/or closed ductus arteriosus. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAortopulmonary collateral arteries

Conditions with this feature

Right atrial isomerism
MedGen UID:
465274
Concept ID:
C3178806
Congenital Abnormality
Right atrial isomerism is characterized by bilateral triangular, morphologically right atrial, appendages, both joining the atrial chamber along a broad front with internal terminal crest.
Heterotaxy, visceral, 8, autosomal
MedGen UID:
934635
Concept ID:
C4310668
Disease or Syndrome
Autosomal visceral heterotaxy-8 (HTX8) is an autosomal recessive developmental disorder characterized by visceral situs inversus associated with complex congenital heart malformations caused by defects in the normal left-right asymmetric positioning of internal organs (summary by Vetrini et al., 2016). For a discussion of the genetic heterogeneity of visceral heterotaxy, see HTX1 (306955).
Gabriele de Vries syndrome
MedGen UID:
1375401
Concept ID:
C4479652
Disease or Syndrome
Gabriele-de Vries syndrome is characterized by mild-to-profound developmental delay / intellectual disability (DD/ID) in all affected individuals and a wide spectrum of functional and morphologic abnormalities. Intrauterine growth restriction or low birth weight and feeding difficulties are common. Congenital brain, eye, heart, kidney, genital, and/or skeletal system anomalies have also been reported. About half of affected individuals have neurologic manifestations, including hypotonia and gait abnormalities. Behavioral issues can include attention-deficit/hyperactivity disorder, anxiety, autism or autistic behavior, and schizoaffective disorder.
Congenital heart defects, multiple types, 7
MedGen UID:
1714491
Concept ID:
C5394062
Congenital Abnormality
Multiple types of congenital heart defects-7 (CHTD7) is an autosomal dominant disorder with incomplete penetrance characterized mainly by tetralogy of Fallot but also including right-sided aortic arch, absent pulmonary valve, and other cardiac abnormalities (Jin et al., 2017, Reuter et al., 2019).
Diaphragmatic hernia 4, with cardiovascular defects
MedGen UID:
1823983
Concept ID:
C5774210
Disease or Syndrome
Diaphragmatic hernia-4 with cardiovascular defects (DIH4) is an autosomal recessive congenital anomaly syndrome characterized by the presence of diaphragmatic hernia or eventration apparent at birth. Affected infants have associated pulmonary hypoplasia and respiratory insufficiency resulting in death in infancy. Most also have variable cardiovascular defects, including aortopulmonary window or conotruncal anomalies. Dysmorphic facial features and mild distal limb anomalies are sometimes observed (Beecroft et al., 2021). For a discussion of genetic heterogeneity of congenital diaphragmatic hernia (CDH), see DIH1 (142340).
Congenital heart defects, multiple types, 9
MedGen UID:
1841003
Concept ID:
C5830367
Congenital Abnormality
Multiple types of congenital heart defects-9 (CHTD9) is characterized by common arterial trunk (truncus arteriosus communis) in most patients, associated with other cardiac defects, including tetralogy of Fallot, interrupted aortic arch, right aortic arch, ventricular hypoplasia, and hypoplastic left heart, as well as other vascular and valvular anomalies (Ta-Shma et al., 2013; Guimier et al., 2023). For a general phenotypic description and discussion of genetic heterogeneity of multiple types of congenital heart defects, see CHTD1 (see 306955).

Professional guidelines

PubMed

Gindes L, Salem Y, Gasnier R, Raucher A, Tamir A, Assa S, Weissman-Brenner A, Weisz B, Kasif E, Achiron R
J Matern Fetal Neonatal Med 2022 Dec;35(25):5400-5408. Epub 2021 Feb 1 doi: 10.1080/14767058.2021.1881475. PMID: 33525939
Gottschalk I, Strizek B, Jehle C, Stressig R, Herberg U, Breuer J, Brockmeier K, Hellmund A, Geipel A, Gembruch U, Berg C
Ultraschall Med 2020 Oct;41(5):514-525. Epub 2019 Jan 7 doi: 10.1055/a-0770-2832. PMID: 30616264
Moszura T, Janiak K, Respondek-Liberska M, Mazurek-Kula A, Dryżek P, Moll J, Sysa A
Kardiol Pol 2011;69(2):146-51. PMID: 21332055

Recent clinical studies

Etiology

McElhinney DB, Asija R, Zhang Y, Jaggi A, Shek J, Peng LF, Boltz MG, Ma M, Martin E, Hanley FL
J Am Coll Cardiol 2023 Sep 19;82(12):1206-1222. doi: 10.1016/j.jacc.2023.06.041. PMID: 37704311
Mainwaring RD, Felmly LM, Hanley FL
World J Pediatr Congenit Heart Surg 2023 Nov;14(6):729-735. Epub 2023 Jul 27 doi: 10.1177/21501351231183970. PMID: 37499043
Strobel RJ, Young AM, Kron IL
J Card Surg 2022 Sep;37(9):2651-2652. Epub 2022 Jun 3 doi: 10.1111/jocs.16651. PMID: 35661266Free PMC Article
Nakamura Y, Burkhart HM
J Card Surg 2022 Apr;37(4):967-968. Epub 2022 Feb 9 doi: 10.1111/jocs.16296. PMID: 35137983
Eltayeb O, Mongé MC, Popescu AR, Sarwark AE, Harris T, Backer CL
World J Pediatr Congenit Heart Surg 2017 Jan;8(1):106-110. Epub 2016 Jun 22 doi: 10.1177/2150135115618871. PMID: 26993757

Diagnosis

Doulamis IP, Marathe SP, Oh NA, Saeed MY, Muter A, Del Nido PJ, Nathan M
World J Pediatr Congenit Heart Surg 2022 Mar;13(2):146-154. doi: 10.1177/21501351211064140. PMID: 35238700
Zucker EJ
Pediatr Radiol 2022 Dec;52(13):2485-2497. Epub 2021 Aug 24 doi: 10.1007/s00247-021-05179-5. PMID: 34427695
Gindes L, Salem Y, Gasnier R, Raucher A, Tamir A, Assa S, Weissman-Brenner A, Weisz B, Kasif E, Achiron R
J Matern Fetal Neonatal Med 2022 Dec;35(25):5400-5408. Epub 2021 Feb 1 doi: 10.1080/14767058.2021.1881475. PMID: 33525939
Eltayeb O, Mongé MC, Popescu AR, Sarwark AE, Harris T, Backer CL
World J Pediatr Congenit Heart Surg 2017 Jan;8(1):106-110. Epub 2016 Jun 22 doi: 10.1177/2150135115618871. PMID: 26993757
Moszura T, Janiak K, Respondek-Liberska M, Mazurek-Kula A, Dryżek P, Moll J, Sysa A
Kardiol Pol 2011;69(2):146-51. PMID: 21332055

Therapy

Schmiel M, Ono M, Staehler H, Georgiev S, Burri M, Heinisch PP, Strbad M, Ewert P, Hager A, Hörer J
Semin Thorac Cardiovasc Surg 2023 Winter;35(4):746-756. Epub 2022 Aug 23 doi: 10.1053/j.semtcvs.2022.08.005. PMID: 36007868
Schmiel M, Kido T, Georgiev S, Burri M, Heinisch PP, Vodiskar J, Strbad M, Ewert P, Hager A, Hörer J, Ono M
Interact Cardiovasc Thorac Surg 2022 Jul 9;35(2) doi: 10.1093/icvts/ivac190. PMID: 35876534Free PMC Article
Satoh A, Yoshioka D, Toda K, Sawa Y
Eur J Cardiothorac Surg 2020 Jan 1;57(1):195. doi: 10.1093/ejcts/ezz239. PMID: 31501861
Zhao D, Yang K, Li S, Yan J, Hua Z, Fang N, Su W, Lv X, Yu B
Eur J Cardiothorac Surg 2019 May 1;55(5):837-844. doi: 10.1093/ejcts/ezy375. PMID: 30481309
Luo S, Grosse-Wortmann L, Propst EJ, Magerman J, Van Arsdell GS, Honjo O
Ann Thorac Surg 2019 Mar;107(3):844-851. Epub 2018 Oct 23 doi: 10.1016/j.athoracsur.2018.08.090. PMID: 30365953

Prognosis

Mainwaring RD, Felmly LM, Hanley FL
World J Pediatr Congenit Heart Surg 2023 Nov;14(6):729-735. Epub 2023 Jul 27 doi: 10.1177/21501351231183970. PMID: 37499043
Doulamis IP, Marathe SP, Oh NA, Saeed MY, Muter A, Del Nido PJ, Nathan M
World J Pediatr Congenit Heart Surg 2022 Mar;13(2):146-154. doi: 10.1177/21501351211064140. PMID: 35238700
Zucker EJ
Pediatr Radiol 2022 Dec;52(13):2485-2497. Epub 2021 Aug 24 doi: 10.1007/s00247-021-05179-5. PMID: 34427695
Luo S, Grosse-Wortmann L, Propst EJ, Magerman J, Van Arsdell GS, Honjo O
Ann Thorac Surg 2019 Mar;107(3):844-851. Epub 2018 Oct 23 doi: 10.1016/j.athoracsur.2018.08.090. PMID: 30365953
Presnell LB, Blankenship A, Cheatham SL, Owens GE, Staveski SL
World J Pediatr Congenit Heart Surg 2015 Oct;6(4):630-9. doi: 10.1177/2150135115598559. PMID: 26467877

Clinical prediction guides

Kamalı H, Tanıdır İC, Öztürk E, Paksoy S, Guzeltas A, Haydin S, Hatemi AC
Cardiol Young 2023 Nov;33(11):2363-2368. Epub 2023 Oct 13 doi: 10.1017/S1047951123003384. PMID: 37828857
Schmiel M, Kido T, Georgiev S, Burri M, Heinisch PP, Vodiskar J, Strbad M, Ewert P, Hager A, Hörer J, Ono M
Interact Cardiovasc Thorac Surg 2022 Jul 9;35(2) doi: 10.1093/icvts/ivac190. PMID: 35876534Free PMC Article
Doulamis IP, Marathe SP, Oh NA, Saeed MY, Muter A, Del Nido PJ, Nathan M
World J Pediatr Congenit Heart Surg 2022 Mar;13(2):146-154. doi: 10.1177/21501351211064140. PMID: 35238700
van de Woestijne PC, Cuypers JAAE, Helbing WA, Bogers AJJC
World J Pediatr Congenit Heart Surg 2021 Mar;12(2):230-233. doi: 10.1177/2150135120976135. PMID: 33684007Free PMC Article
Luo S, Grosse-Wortmann L, Propst EJ, Magerman J, Van Arsdell GS, Honjo O
Ann Thorac Surg 2019 Mar;107(3):844-851. Epub 2018 Oct 23 doi: 10.1016/j.athoracsur.2018.08.090. PMID: 30365953

Recent systematic reviews

Doulamis IP, Marathe SP, Oh NA, Saeed MY, Muter A, Del Nido PJ, Nathan M
World J Pediatr Congenit Heart Surg 2022 Mar;13(2):146-154. doi: 10.1177/21501351211064140. PMID: 35238700

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