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Childhood Anaplastic Astrocytoma

MedGen UID:
1635918
•Concept ID:
C4551548
•
Neoplastic Process
Synonyms: Anaplastic Childhood Astrocytoma; Anaplastic Pediatric Astrocytoma; Grade 3 Childhood Astrocytic Neoplasm; Grade 3 Childhood Astrocytic Tumor; Grade 3 Childhood Astrocytoma; Grade 3 Pediatric Astrocytic Neoplasm; Grade 3 Pediatric Astrocytic Tumor; Grade 3 Pediatric Astrocytoma; Grade III Childhood Astrocytic Neoplasm; Grade III Childhood Astrocytic Tumor; Grade III Childhood Astrocytoma; Grade III Pediatric Astrocytic Neoplasm; Grade III Pediatric Astrocytic Tumor; Grade III Pediatric Astrocytoma; Undifferentiated Childhood Astrocytoma; Undifferentiated Pediatric Astrocytoma

Definition

An anaplastic astrocytoma that arises from the central nervous system and occurs during childhood. [from NCI]

Professional guidelines

PubMed

Clinical Features, Treatment and Outcome of Childhood Glial Tumors.
Kara B, Ertan K, Karabagli P, Karabagli H, Yavas G, Caglayan AO, Koksal Y
Turk Neurosurg 2022;32(1):135-142. doi: 10.5137/1019-5149.JTN.34801-21.2. PMID: 34751424
Diagnosis and Treatment of Pediatric Brain Tumors.
Hodžić M, Ercegović Z, Korkut D, Moranjkić M, Brkić H, Jakupović S
Acta Med Acad 2020;49 Suppl 1:37-44. doi: 10.5644/ama2006-124.305. PMID: 33543629
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699Free PMC Article

Recent clinical studies

Etiology

Phase II study of 6-thioguanine, procarbazine, dibromodulcitol, lomustine, and vincristine chemotherapy with radiotherapy for treating malignant glioma in children.
Levin VA, Lamborn K, Wara W, Davis R, Edwards M, Rabbitt J, Malec M, Prados MD
Neuro Oncol 2000 Jan;2(1):22-8. doi: 10.1093/neuonc/2.1.22. PMID: 11302250Free PMC Article

Therapy

Phase II study of 6-thioguanine, procarbazine, dibromodulcitol, lomustine, and vincristine chemotherapy with radiotherapy for treating malignant glioma in children.
Levin VA, Lamborn K, Wara W, Davis R, Edwards M, Rabbitt J, Malec M, Prados MD
Neuro Oncol 2000 Jan;2(1):22-8. doi: 10.1093/neuonc/2.1.22. PMID: 11302250Free PMC Article

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