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Advanced Microsatellite Stable Colorectal Carcinoma

MedGen UID:
1640632
Concept ID:
C4684878
Neoplastic Process
Synonym: Advanced Microsatellite Stable Colorectal Cancer

Definition

A microsatellite stable carcinoma that arises from the colon or rectum and has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Microsatellite Stable Colorectal Carcinoma

Professional guidelines

PubMed

Lumish MA, Cercek A
J Surg Oncol 2021 Mar;123(3):760-774. doi: 10.1002/jso.26357. PMID: 33595891
Murakami T, Sakamoto N, Nagahara A
J Gastroenterol Hepatol 2019 Oct;34(10):1685-1695. Epub 2019 Jun 30 doi: 10.1111/jgh.14752. PMID: 31158302
Chang L, Chang M, Chang HM, Chang F
J Gastrointest Cancer 2017 Dec;48(4):305-313. doi: 10.1007/s12029-017-9991-0. PMID: 28699072Free PMC Article

Recent clinical studies

Etiology

Saraiva MR, Rosa I, Claro I
World J Gastroenterol 2023 Feb 28;29(8):1289-1303. doi: 10.3748/wjg.v29.i8.1289. PMID: 36925459Free PMC Article
Chatila WK, Kim JK, Walch H, Marco MR, Chen CT, Wu F, Omer DM, Khalil DN, Ganesh K, Qu X, Luthra A, Choi SH, Ho YJ, Kundra R, Groves KI, Chow OS, Cercek A, Weiser MR, Widmar M, Wei IH, Pappou EP, Nash GM, Paty PB, Shi Q, Vakiani E, Duygu Selcuklu S, Donoghue MTA, Solit DB, Berger MF, Shia J, Pelossof R, Romesser PB, Yaeger R, Smith JJ, Schultz N, Sanchez-Vega F, Garcia-Aguilar J
Nat Med 2022 Aug;28(8):1646-1655. Epub 2022 Aug 15 doi: 10.1038/s41591-022-01930-z. PMID: 35970919Free PMC Article
Chen EX, Jonker DJ, Loree JM, Kennecke HF, Berry SR, Couture F, Ahmad CE, Goffin JR, Kavan P, Harb M, Colwell B, Samimi S, Samson B, Abbas T, Aucoin N, Aubin F, Koski SL, Wei AC, Magoski NM, Tu D, O'Callaghan CJ
JAMA Oncol 2020 Jun 1;6(6):831-838. doi: 10.1001/jamaoncol.2020.0910. PMID: 32379280Free PMC Article
Latham A, Srinivasan P, Kemel Y, Shia J, Bandlamudi C, Mandelker D, Middha S, Hechtman J, Zehir A, Dubard-Gault M, Tran C, Stewart C, Sheehan M, Penson A, DeLair D, Yaeger R, Vijai J, Mukherjee S, Galle J, Dickson MA, Janjigian Y, O'Reilly EM, Segal N, Saltz LB, Reidy-Lagunes D, Varghese AM, Bajorin D, Carlo MI, Cadoo K, Walsh MF, Weiser M, Aguilar JG, Klimstra DS, Diaz LA Jr, Baselga J, Zhang L, Ladanyi M, Hyman DM, Solit DB, Robson ME, Taylor BS, Offit K, Berger MF, Stadler ZK
J Clin Oncol 2019 Feb 1;37(4):286-295. Epub 2018 Oct 30 doi: 10.1200/JCO.18.00283. PMID: 30376427Free PMC Article
Müller MF, Ibrahim AE, Arends MJ
Virchows Arch 2016 Aug;469(2):125-34. Epub 2016 Jun 20 doi: 10.1007/s00428-016-1956-3. PMID: 27325016Free PMC Article

Diagnosis

Taraborrelli L, Şenbabaoğlu Y, Wang L, Lim J, Blake K, Kljavin N, Gierke S, Scherl A, Ziai J, McNamara E, Owyong M, Rao S, Calviello AK, Oreper D, Jhunjhunwala S, Argiles G, Bendell J, Kim TW, Ciardiello F, Wongchenko MJ, de Sauvage FJ, de Sousa E Melo F, Yan Y, West NR, Murthy A
Nat Commun 2023 Sep 23;14(1):5945. doi: 10.1038/s41467-023-41618-7. PMID: 37741832Free PMC Article
Saraiva MR, Rosa I, Claro I
World J Gastroenterol 2023 Feb 28;29(8):1289-1303. doi: 10.3748/wjg.v29.i8.1289. PMID: 36925459Free PMC Article
Cercek A, Chatila WK, Yaeger R, Walch H, Fernandes GDS, Krishnan A, Palmaira L, Maio A, Kemel Y, Srinivasan P, Bandlamudi C, Salo-Mullen E, Tejada PR, Belanfanti K, Galle J, Joseph V, Segal N, Varghese A, Reidy-Lagunes D, Shia J, Vakiani E, Mondaca S, Mendelsohn R, Lumish MA, Steinruecke F, Kemeny N, Connell L, Ganesh K, Markowitz A, Nash G, Guillem J, Smith JJ, Paty PB, Zhang L, Mandelker D, Birsoy O, Robson M, Offit K, Taylor B, Berger M, Solit D, Weiser M, Saltz LB, Aguilar JG, Schultz N, Diaz LA, Stadler ZK
J Natl Cancer Inst 2021 Nov 29;113(12):1683-1692. doi: 10.1093/jnci/djab124. PMID: 34405229Free PMC Article
Eng C, Kim TW, Bendell J, Argilés G, Tebbutt NC, Di Bartolomeo M, Falcone A, Fakih M, Kozloff M, Segal NH, Sobrero A, Yan Y, Chang I, Uyei A, Roberts L, Ciardiello F; IMblaze370 Investigators
Lancet Oncol 2019 Jun;20(6):849-861. Epub 2019 Apr 16 doi: 10.1016/S1470-2045(19)30027-0. PMID: 31003911
Chang L, Chang M, Chang HM, Chang F
J Gastrointest Cancer 2017 Dec;48(4):305-313. doi: 10.1007/s12029-017-9991-0. PMID: 28699072Free PMC Article

Therapy

Fakih M, Sandhu J, Lim D, Li X, Li S, Wang C
JAMA Oncol 2023 May 1;9(5):627-634. doi: 10.1001/jamaoncol.2022.7845. PMID: 36892833Free PMC Article
Palmer CD, Rappaport AR, Davis MJ, Hart MG, Scallan CD, Hong SJ, Gitlin L, Kraemer LD, Kounlavouth S, Yang A, Smith L, Schenk D, Skoberne M, Taquechel K, Marrali M, Jaroslavsky JR, Nganje CN, Maloney E, Zhou R, Navarro-Gomez D, Greene AC, Grotenbreg G, Greer R, Blair W, Cao MD, Chan S, Bae K, Spira AI, Roychowdhury S, Carbone DP, Henick BS, Drake CG, Solomon BJ, Ahn DH, Mahipal A, Maron SB, Johnson B, Rousseau R, Yelensky R, Liao CY, Catenacci DVT, Allen A, Ferguson AR, Jooss K
Nat Med 2022 Aug;28(8):1619-1629. Epub 2022 Aug 15 doi: 10.1038/s41591-022-01937-6. PMID: 35970920
Khaliq AM, Erdogan C, Kurt Z, Turgut SS, Grunvald MW, Rand T, Khare S, Borgia JA, Hayden DM, Pappas SG, Govekar HR, Kam AE, Reiser J, Turaga K, Radovich M, Zang Y, Qiu Y, Liu Y, Fishel ML, Turk A, Gupta V, Al-Sabti R, Subramanian J, Kuzel TM, Sadanandam A, Waldron L, Hussain A, Saleem M, El-Rayes B, Salahudeen AA, Masood A
Genome Biol 2022 May 11;23(1):113. doi: 10.1186/s13059-022-02677-z. PMID: 35538548Free PMC Article
Picard E, Verschoor CP, Ma GW, Pawelec G
Front Immunol 2020;11:369. Epub 2020 Mar 6 doi: 10.3389/fimmu.2020.00369. PMID: 32210966Free PMC Article
Müller MF, Ibrahim AE, Arends MJ
Virchows Arch 2016 Aug;469(2):125-34. Epub 2016 Jun 20 doi: 10.1007/s00428-016-1956-3. PMID: 27325016Free PMC Article

Prognosis

Khaliq AM, Erdogan C, Kurt Z, Turgut SS, Grunvald MW, Rand T, Khare S, Borgia JA, Hayden DM, Pappas SG, Govekar HR, Kam AE, Reiser J, Turaga K, Radovich M, Zang Y, Qiu Y, Liu Y, Fishel ML, Turk A, Gupta V, Al-Sabti R, Subramanian J, Kuzel TM, Sadanandam A, Waldron L, Hussain A, Saleem M, El-Rayes B, Salahudeen AA, Masood A
Genome Biol 2022 May 11;23(1):113. doi: 10.1186/s13059-022-02677-z. PMID: 35538548Free PMC Article
Picard E, Verschoor CP, Ma GW, Pawelec G
Front Immunol 2020;11:369. Epub 2020 Mar 6 doi: 10.3389/fimmu.2020.00369. PMID: 32210966Free PMC Article
Latham A, Srinivasan P, Kemel Y, Shia J, Bandlamudi C, Mandelker D, Middha S, Hechtman J, Zehir A, Dubard-Gault M, Tran C, Stewart C, Sheehan M, Penson A, DeLair D, Yaeger R, Vijai J, Mukherjee S, Galle J, Dickson MA, Janjigian Y, O'Reilly EM, Segal N, Saltz LB, Reidy-Lagunes D, Varghese AM, Bajorin D, Carlo MI, Cadoo K, Walsh MF, Weiser M, Aguilar JG, Klimstra DS, Diaz LA Jr, Baselga J, Zhang L, Ladanyi M, Hyman DM, Solit DB, Robson ME, Taylor BS, Offit K, Berger MF, Stadler ZK
J Clin Oncol 2019 Feb 1;37(4):286-295. Epub 2018 Oct 30 doi: 10.1200/JCO.18.00283. PMID: 30376427Free PMC Article
Tauriello DVF, Palomo-Ponce S, Stork D, Berenguer-Llergo A, Badia-Ramentol J, Iglesias M, Sevillano M, Ibiza S, Cañellas A, Hernando-Momblona X, Byrom D, Matarin JA, Calon A, Rivas EI, Nebreda AR, Riera A, Attolini CS, Batlle E
Nature 2018 Feb 22;554(7693):538-543. Epub 2018 Feb 14 doi: 10.1038/nature25492. PMID: 29443964
Müller MF, Ibrahim AE, Arends MJ
Virchows Arch 2016 Aug;469(2):125-34. Epub 2016 Jun 20 doi: 10.1007/s00428-016-1956-3. PMID: 27325016Free PMC Article

Clinical prediction guides

Khaliq AM, Erdogan C, Kurt Z, Turgut SS, Grunvald MW, Rand T, Khare S, Borgia JA, Hayden DM, Pappas SG, Govekar HR, Kam AE, Reiser J, Turaga K, Radovich M, Zang Y, Qiu Y, Liu Y, Fishel ML, Turk A, Gupta V, Al-Sabti R, Subramanian J, Kuzel TM, Sadanandam A, Waldron L, Hussain A, Saleem M, El-Rayes B, Salahudeen AA, Masood A
Genome Biol 2022 May 11;23(1):113. doi: 10.1186/s13059-022-02677-z. PMID: 35538548Free PMC Article
Picard E, Verschoor CP, Ma GW, Pawelec G
Front Immunol 2020;11:369. Epub 2020 Mar 6 doi: 10.3389/fimmu.2020.00369. PMID: 32210966Free PMC Article
Latham A, Srinivasan P, Kemel Y, Shia J, Bandlamudi C, Mandelker D, Middha S, Hechtman J, Zehir A, Dubard-Gault M, Tran C, Stewart C, Sheehan M, Penson A, DeLair D, Yaeger R, Vijai J, Mukherjee S, Galle J, Dickson MA, Janjigian Y, O'Reilly EM, Segal N, Saltz LB, Reidy-Lagunes D, Varghese AM, Bajorin D, Carlo MI, Cadoo K, Walsh MF, Weiser M, Aguilar JG, Klimstra DS, Diaz LA Jr, Baselga J, Zhang L, Ladanyi M, Hyman DM, Solit DB, Robson ME, Taylor BS, Offit K, Berger MF, Stadler ZK
J Clin Oncol 2019 Feb 1;37(4):286-295. Epub 2018 Oct 30 doi: 10.1200/JCO.18.00283. PMID: 30376427Free PMC Article
Tauriello DVF, Palomo-Ponce S, Stork D, Berenguer-Llergo A, Badia-Ramentol J, Iglesias M, Sevillano M, Ibiza S, Cañellas A, Hernando-Momblona X, Byrom D, Matarin JA, Calon A, Rivas EI, Nebreda AR, Riera A, Attolini CS, Batlle E
Nature 2018 Feb 22;554(7693):538-543. Epub 2018 Feb 14 doi: 10.1038/nature25492. PMID: 29443964
Müller MF, Ibrahim AE, Arends MJ
Virchows Arch 2016 Aug;469(2):125-34. Epub 2016 Jun 20 doi: 10.1007/s00428-016-1956-3. PMID: 27325016Free PMC Article

Recent systematic reviews

Travaglino A, Raffone A, Santoro A, Raimondo D, Orsini B, Casadio P, Zullo F, Seracchioli R, Zannoni GF, Insabato L, Mollo A
Pathobiology 2022;89(4):198-204. Epub 2022 Mar 1 doi: 10.1159/000521876. PMID: 35231921
Aggarwal N, Quaglia A, McPhail MJW, Monahan KJ
Int J Colorectal Dis 2022 Jan;37(1):35-46. Epub 2021 Oct 22 doi: 10.1007/s00384-021-04046-x. PMID: 34677685Free PMC Article
O'Connell E, Reynolds IS, McNamara DA, Prehn JHM, Burke JP
Surg Oncol 2020 Sep;34:57-62. Epub 2020 Apr 2 doi: 10.1016/j.suronc.2020.03.009. PMID: 32891354

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