U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal ascending aorta morphology

MedGen UID:
1645394
Concept ID:
C4703539
Anatomical Abnormality
HPO: HP:0031784

Definition

Any structural anomaly of the portion of the aorta that arises from the base of the left ventricle and extends upward to the aortic arch and from which the coronary arteries arise. [from HPO]

Professional guidelines

PubMed

Tretter JT, Spicer DE, Franklin RCG, Béland MJ, Aiello VD, Cook AC, Crucean A, Loomba RS, Yoo SJ, Quintessenza JA, Tchervenkov CI, Jacobs JP, Najm HK, Anderson RH
Ann Thorac Surg 2023 Jul;116(1):6-16. Epub 2023 Jun 8 doi: 10.1016/j.athoracsur.2023.03.023. PMID: 37294261
Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ
J Thorac Cardiovasc Surg 2021 Sep;162(3):e383-e414. Epub 2021 Jul 22 doi: 10.1016/j.jtcvs.2021.06.019. PMID: 34304896
Riambau V, Böckler D, Brunkwall J, Cao P, Chiesa R, Coppi G, Czerny M, Fraedrich G, Haulon S, Jacobs MJ, Lachat ML, Moll FL, Setacci C, Taylor PR, Thompson M, Trimarchi S, Verhagen HJ, Verhoeven EL, Esvs Guidelines Committee, Kolh P, de Borst GJ, Chakfé N, Debus ES, Hinchliffe RJ, Kakkos S, Koncar I, Lindholt JS, Vega de Ceniga M, Vermassen F, Verzini F, Document Reviewers, Kolh P, Black JH 3rd, Busund R, Björck M, Dake M, Dick F, Eggebrecht H, Evangelista A, Grabenwöger M, Milner R, Naylor AR, Ricco JB, Rousseau H, Schmidli J
Eur J Vasc Endovasc Surg 2017 Jan;53(1):4-52. doi: 10.1016/j.ejvs.2016.06.005. PMID: 28081802

Recent clinical studies

Etiology

Lin R, Jiang R, Wang S, Zheng J, Sun Y, Xue Y, Huang X
J Vasc Surg 2022 Oct;76(4):891-898.e2. Epub 2022 Jun 23 doi: 10.1016/j.jvs.2022.06.021. PMID: 35753651
Haranal M, Srimurugan B, Sivalingam S
Asian Cardiovasc Thorac Ann 2022 Feb;30(2):217-225. Epub 2021 May 6 doi: 10.1177/02184923211015092. PMID: 33957784
Karangelis D, Loggos S, Tzifa A, Mitropoulos FA
Curr Opin Cardiol 2020 Nov;35(6):636-642. doi: 10.1097/HCO.0000000000000793. PMID: 32852349
Yoshimura N, Fukahara K, Yamashita A, Doi T, Yamashita S, Homma T, Yokoyama S, Aoki M, Higashida A, Shimada Y, Toritsuka D, Nagao K, Ikeno Y
Surg Today 2020 Oct;50(10):1151-1158. Epub 2019 Nov 1 doi: 10.1007/s00595-019-01907-5. PMID: 31676999
Friedman K
Semin Cardiothorac Vasc Anesth 2018 Sep;22(3):265-269. Epub 2018 Apr 12 doi: 10.1177/1089253218770198. PMID: 29649938

Diagnosis

Yoshimura N, Fukahara K, Yamashita A, Doi T, Yamashita S, Homma T, Yokoyama S, Aoki M, Higashida A, Shimada Y, Toritsuka D, Nagao K, Ikeno Y
Surg Today 2020 Oct;50(10):1151-1158. Epub 2019 Nov 1 doi: 10.1007/s00595-019-01907-5. PMID: 31676999
Friedman K
Semin Cardiothorac Vasc Anesth 2018 Sep;22(3):265-269. Epub 2018 Apr 12 doi: 10.1177/1089253218770198. PMID: 29649938
Hanneman K, Newman B, Chan F
Radiographics 2017 Jan-Feb;37(1):32-51. Epub 2016 Nov 18 doi: 10.1148/rg.2017160033. PMID: 27860551
Smith BM, Lu JC, Dorfman AL, Mahani MG, Agarwal PP
Magn Reson Imaging Clin N Am 2015 Feb;23(1):127-35. Epub 2014 Oct 3 doi: 10.1016/j.mric.2014.09.011. PMID: 25476681
Kellenberger CJ
Pediatr Radiol 2010 Jun;40(6):876-84. Epub 2010 Mar 31 doi: 10.1007/s00247-010-1607-9. PMID: 20354848

Therapy

Wojnarski CM, Roselli EE, Idrees JJ, Zhu Y, Carnes TA, Lowry AM, Collier PH, Griffin B, Ehrlinger J, Blackstone EH, Svensson LG, Lytle BW
J Thorac Cardiovasc Surg 2018 Feb;155(2):461-469.e4. Epub 2017 Sep 14 doi: 10.1016/j.jtcvs.2017.08.123. PMID: 29042101
Riambau V, Böckler D, Brunkwall J, Cao P, Chiesa R, Coppi G, Czerny M, Fraedrich G, Haulon S, Jacobs MJ, Lachat ML, Moll FL, Setacci C, Taylor PR, Thompson M, Trimarchi S, Verhagen HJ, Verhoeven EL, Esvs Guidelines Committee, Kolh P, de Borst GJ, Chakfé N, Debus ES, Hinchliffe RJ, Kakkos S, Koncar I, Lindholt JS, Vega de Ceniga M, Vermassen F, Verzini F, Document Reviewers, Kolh P, Black JH 3rd, Busund R, Björck M, Dake M, Dick F, Eggebrecht H, Evangelista A, Grabenwöger M, Milner R, Naylor AR, Ricco JB, Rousseau H, Schmidli J
Eur J Vasc Endovasc Surg 2017 Jan;53(1):4-52. doi: 10.1016/j.ejvs.2016.06.005. PMID: 28081802
Raffa GM, Kowalewski M, Malvindi PG, Bertani A, Romano G, Sciacca S, Turrisi M, Armaro A, Stringi V, Montalbano G, Mattiucci G, Follis F, Pilato M
J Cardiovasc Med (Hagerstown) 2017 May;18(5):305-310. doi: 10.2459/JCM.0000000000000394. PMID: 27136701
Wilton E, Jahangiri M
J Cardiothorac Surg 2006 Mar 3;1:7. doi: 10.1186/1749-8090-1-7. PMID: 16722611Free PMC Article
Israel G, Krinsky G, Lee V
Clin Imaging 2002 Mar-Apr;26(2):116-21. doi: 10.1016/s0899-7071(01)00368-0. PMID: 11852219

Prognosis

He X, Chen J, Li G
Cardiovasc Ultrasound 2021 Jan 14;19(1):8. doi: 10.1186/s12947-021-00237-2. PMID: 33446185Free PMC Article
Brothers JA
Congenit Heart Dis 2017 Sep;12(5):600-602. Epub 2017 Jun 27 doi: 10.1111/chd.12497. PMID: 28653465
Hanneman K, Newman B, Chan F
Radiographics 2017 Jan-Feb;37(1):32-51. Epub 2016 Nov 18 doi: 10.1148/rg.2017160033. PMID: 27860551
Raimondi F, Bonnet D
Diagn Interv Imaging 2016 May;97(5):561-9. Epub 2016 Apr 26 doi: 10.1016/j.diii.2016.03.009. PMID: 27132711
Mavroudis C, Mavroudis CD, Jacobs JP
Cardiol Young 2015 Dec;25(8):1546-60. doi: 10.1017/S1047951115002048. PMID: 26675603

Clinical prediction guides

Giuliani L, Di Toro A, Urtis M, Narula N, Grasso M, Pelenghi S, Belliato M, Bozzani A, Arici V, Pellegrini C, Serio A, Pilotto A, Fergnani V, Antoniazzi E, Magrassi L, Dore R, Valentini A, Preda L, Calliada F, Quaretti P, Pirrelli S, Kodama T, Vricella L, Cameron D, Arbustini E
J Am Coll Cardiol 2023 Mar 14;81(10):979-991. doi: 10.1016/j.jacc.2023.01.005. PMID: 36889877
Fletcher AJ, Syed MBJ, Aitman TJ, Newby DE, Walker NL
Circulation 2020 May 12;141(19):1570-1587. Epub 2020 May 11 doi: 10.1161/CIRCULATIONAHA.119.043756. PMID: 32392100Free PMC Article
Maredia AK, Greenway SC, Verma S, Fedak PWM
Curr Opin Cardiol 2018 Mar;33(2):134-139. doi: 10.1097/HCO.0000000000000481. PMID: 29095713
Yuan SM
Braz J Cardiovasc Surg 2016 Feb;31(1):52-9. doi: 10.5935/1678-9741.20150071. PMID: 27074275Free PMC Article
McKay R
Orphanet J Rare Dis 2007 Oct 8;2:41. doi: 10.1186/1750-1172-2-41. PMID: 17922908Free PMC Article

Recent systematic reviews

Loschi D, Santoro A, Rinaldi E, Bilman V, Chiesa R, Melissano G
J Vasc Surg 2023 Feb;77(2):642-649.e4. Epub 2022 Jul 15 doi: 10.1016/j.jvs.2022.07.010. PMID: 35850164
Konstantinou N, Antonopoulos CN, Tzanis K, Kölbel T, Peterß S, Pichlmaier M, Stana J, Tsilimparis N
Eur J Vasc Endovasc Surg 2022 May;63(5):759-767. Epub 2022 Feb 25 doi: 10.1016/j.ejvs.2022.02.027. PMID: 35459610
Miśkowiec D, Lipiec P, Szymczyk E, Wejner-Mik P, Michalski B, Kupczyńska K, Wierzbowska-Drabik K, Kasprzak JD
Echocardiography 2018 May;35(5):667-677. Epub 2018 Feb 4 doi: 10.1111/echo.13818. PMID: 29399873
Singh S, Hakim FA, Sharma A, Roy RR, Panse PM, Chandrasekaran K, Alegria JR, Mookadam F
Heart Lung Circ 2015 Feb;24(2):110-8. Epub 2014 Aug 23 doi: 10.1016/j.hlc.2014.08.006. PMID: 25442062
Abdulkareem N, Smelt J, Jahangiri M
Interact Cardiovasc Thorac Surg 2013 Sep;17(3):554-9. Epub 2013 May 31 doi: 10.1093/icvts/ivt196. PMID: 23728086Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...