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Unresectable Low Grade Glioma

MedGen UID:
1656726
•Concept ID:
C4744408
•
Neoplastic Process
Synonym: Unresectable Low-Grade Glioma

Definition

Low grade glioma that is not amenable to surgical removal. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Low Grade Glioma

Professional guidelines

PubMed

Risk assessment in paediatric glioma-Time to move on from the binary classification.
Dodgshun AJ, Hansford JR, Sullivan MJ
Crit Rev Oncol Hematol 2017 Mar;111:52-59. Epub 2017 Jan 23 doi: 10.1016/j.critrevonc.2017.01.012. PMID: 28259295

Recent clinical studies

Etiology

Children's Oncology Group's 2023 blueprint for research: Central nervous system tumors.
Leary SES, Onar-Thomas A, Fangusaro J, Gottardo NG, Cohen K, Smith A, Huang A, Haas-Kogan D, Fouladi M; COG Central Nervous System Committee
Pediatr Blood Cancer 2023 Sep;70 Suppl 6(Suppl 6):e30600. Epub 2023 Aug 3 doi: 10.1002/pbc.30600. PMID: 37534382Free PMC Article
Risk assessment in paediatric glioma-Time to move on from the binary classification.
Dodgshun AJ, Hansford JR, Sullivan MJ
Crit Rev Oncol Hematol 2017 Mar;111:52-59. Epub 2017 Jan 23 doi: 10.1016/j.critrevonc.2017.01.012. PMID: 28259295
Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma.
Bouffet E, Jakacki R, Goldman S, Hargrave D, Hawkins C, Shroff M, Hukin J, Bartels U, Foreman N, Kellie S, Hilden J, Etzl M, Wilson B, Stephens D, Tabori U, Baruchel S
J Clin Oncol 2012 Apr 20;30(12):1358-63. Epub 2012 Mar 5 doi: 10.1200/JCO.2011.34.5843. PMID: 22393086

Diagnosis

Children's Oncology Group's 2023 blueprint for research: Central nervous system tumors.
Leary SES, Onar-Thomas A, Fangusaro J, Gottardo NG, Cohen K, Smith A, Huang A, Haas-Kogan D, Fouladi M; COG Central Nervous System Committee
Pediatr Blood Cancer 2023 Sep;70 Suppl 6(Suppl 6):e30600. Epub 2023 Aug 3 doi: 10.1002/pbc.30600. PMID: 37534382Free PMC Article
Risk assessment in paediatric glioma-Time to move on from the binary classification.
Dodgshun AJ, Hansford JR, Sullivan MJ
Crit Rev Oncol Hematol 2017 Mar;111:52-59. Epub 2017 Jan 23 doi: 10.1016/j.critrevonc.2017.01.012. PMID: 28259295
Single agent vinorelbine in pediatric patients with progressive optic pathway glioma.
Cappellano AM, Petrilli AS, da Silva NS, Silva FA, Paiva PM, Cavalheiro S, Bouffet E
J Neurooncol 2015 Jan;121(2):405-12. Epub 2014 Nov 1 doi: 10.1007/s11060-014-1652-6. PMID: 25366366
Weekly vinblastine in pediatric low-grade glioma patients with carboplatin allergic reaction.
Lafay-Cousin L, Holm S, Qaddoumi I, Nicolin G, Bartels U, Tabori U, Huang A, Bouffet E
Cancer 2005 Jun 15;103(12):2636-42. doi: 10.1002/cncr.21091. PMID: 15861409

Therapy

Single agent vinorelbine in pediatric patients with progressive optic pathway glioma.
Cappellano AM, Petrilli AS, da Silva NS, Silva FA, Paiva PM, Cavalheiro S, Bouffet E
J Neurooncol 2015 Jan;121(2):405-12. Epub 2014 Nov 1 doi: 10.1007/s11060-014-1652-6. PMID: 25366366
Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma.
Bouffet E, Jakacki R, Goldman S, Hargrave D, Hawkins C, Shroff M, Hukin J, Bartels U, Foreman N, Kellie S, Hilden J, Etzl M, Wilson B, Stephens D, Tabori U, Baruchel S
J Clin Oncol 2012 Apr 20;30(12):1358-63. Epub 2012 Mar 5 doi: 10.1200/JCO.2011.34.5843. PMID: 22393086
Weekly vinblastine in pediatric low-grade glioma patients with carboplatin allergic reaction.
Lafay-Cousin L, Holm S, Qaddoumi I, Nicolin G, Bartels U, Tabori U, Huang A, Bouffet E
Cancer 2005 Jun 15;103(12):2636-42. doi: 10.1002/cncr.21091. PMID: 15861409

Prognosis

Children's Oncology Group's 2023 blueprint for research: Central nervous system tumors.
Leary SES, Onar-Thomas A, Fangusaro J, Gottardo NG, Cohen K, Smith A, Huang A, Haas-Kogan D, Fouladi M; COG Central Nervous System Committee
Pediatr Blood Cancer 2023 Sep;70 Suppl 6(Suppl 6):e30600. Epub 2023 Aug 3 doi: 10.1002/pbc.30600. PMID: 37534382Free PMC Article
Risk assessment in paediatric glioma-Time to move on from the binary classification.
Dodgshun AJ, Hansford JR, Sullivan MJ
Crit Rev Oncol Hematol 2017 Mar;111:52-59. Epub 2017 Jan 23 doi: 10.1016/j.critrevonc.2017.01.012. PMID: 28259295
Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma.
Bouffet E, Jakacki R, Goldman S, Hargrave D, Hawkins C, Shroff M, Hukin J, Bartels U, Foreman N, Kellie S, Hilden J, Etzl M, Wilson B, Stephens D, Tabori U, Baruchel S
J Clin Oncol 2012 Apr 20;30(12):1358-63. Epub 2012 Mar 5 doi: 10.1200/JCO.2011.34.5843. PMID: 22393086

Clinical prediction guides

Single agent vinorelbine in pediatric patients with progressive optic pathway glioma.
Cappellano AM, Petrilli AS, da Silva NS, Silva FA, Paiva PM, Cavalheiro S, Bouffet E
J Neurooncol 2015 Jan;121(2):405-12. Epub 2014 Nov 1 doi: 10.1007/s11060-014-1652-6. PMID: 25366366
Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma.
Bouffet E, Jakacki R, Goldman S, Hargrave D, Hawkins C, Shroff M, Hukin J, Bartels U, Foreman N, Kellie S, Hilden J, Etzl M, Wilson B, Stephens D, Tabori U, Baruchel S
J Clin Oncol 2012 Apr 20;30(12):1358-63. Epub 2012 Mar 5 doi: 10.1200/JCO.2011.34.5843. PMID: 22393086

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