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Recurrent Breast Paget Disease

MedGen UID:
1667595
•Concept ID:
C4727376
•
Neoplastic Process
Synonyms: Recurrent Paget Disease of the Breast; Recurrent Paget's Disease of the Breast

Definition

The reemergence of Paget disease of the breast after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Breast Paget Disease

Professional guidelines

PubMed

Multidisciplinary management of mammary Paget's disease: recommendations to optimize oncological and aesthetic outcomes.
Franceschini G, Mason EJ, Di Leone A, Scardina L, Masetti R
Ann Ital Chir 2022;93:481-482. PMID: 36196555
Interventions for the treatment of Paget's disease of the vulva.
Edey KA, Allan E, Murdoch JB, Cooper S, Bryant A
Cochrane Database Syst Rev 2013 Oct 26;(10):CD009245. doi: 10.1002/14651858.CD009245.pub2. PMID: 24163070
The management of Paget's disease of the breast.
Marcus E
Curr Treat Options Oncol 2004 Apr;5(2):153-60. doi: 10.1007/s11864-004-0047-x. PMID: 14990209

Recent clinical studies

Etiology

Treatment of Mammary Paget Disease: A systematic review and meta-analysis of real-world data.
Lin CW, Chiang MH, Tam KW
Int J Surg 2022 Nov;107:106964. Epub 2022 Oct 26 doi: 10.1016/j.ijsu.2022.106964. PMID: 36309195
Vulval extra-mammary Paget's disease: the master of disguise revealed.
O'Neill D, Evans M, Nunns D, El-Ghobashy A
Br J Hosp Med (Lond) 2022 Feb 2;83(2):1-12. Epub 2022 Feb 10 doi: 10.12968/hmed.2021.0536. PMID: 35243879
More advantages in detecting bone and soft tissue metastases from prostate cancer using (18)F-PSMA PET/CT.
Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003
Cutaneous manifestations of breast cancer.
Tan AR
Semin Oncol 2016 Jun;43(3):331-4. Epub 2016 Feb 23 doi: 10.1053/j.seminoncol.2016.02.030. PMID: 27178684
Effectiveness of photodynamic therapy for mammary and extra-mammary Paget's disease: a state of the science review.
Nardelli AA, Stafinski T, Menon D
BMC Dermatol 2011 Jun 15;11:13. doi: 10.1186/1471-5945-11-13. PMID: 21676258Free PMC Article

Diagnosis

Vulval extra-mammary Paget's disease: the master of disguise revealed.
O'Neill D, Evans M, Nunns D, El-Ghobashy A
Br J Hosp Med (Lond) 2022 Feb 2;83(2):1-12. Epub 2022 Feb 10 doi: 10.12968/hmed.2021.0536. PMID: 35243879
More advantages in detecting bone and soft tissue metastases from prostate cancer using (18)F-PSMA PET/CT.
Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003
Skin diseases of the breast and nipple: Benign and malignant tumors.
Waldman RA, Finch J, Grant-Kels JM, Stevenson C, Whitaker-Worth D
J Am Acad Dermatol 2019 Jun;80(6):1467-1481. Epub 2018 Nov 16 doi: 10.1016/j.jaad.2018.08.066. PMID: 30452954
Cutaneous manifestations of breast cancer.
Tan AR
Semin Oncol 2016 Jun;43(3):331-4. Epub 2016 Feb 23 doi: 10.1053/j.seminoncol.2016.02.030. PMID: 27178684
Mammary and extramammary Paget's disease.
Lopes Filho LL, Lopes IM, Lopes LR, Enokihara MM, Michalany AO, Matsunaga N
An Bras Dermatol 2015 Mar-Apr;90(2):225-31. doi: 10.1590/abd1806-4841.20153189. PMID: 25830993Free PMC Article

Therapy

The role of HER2 as a therapeutic biomarker in gynaecological malignancy: potential for use beyond uterine serous carcinoma.
Talia KL, Banet N, Buza N
Pathology 2023 Feb;55(1):8-18. Epub 2022 Nov 23 doi: 10.1016/j.pathol.2022.11.004. PMID: 36503635
The Paget Trial: topical 5% imiquimod cream for noninvasive vulvar Paget disease.
van der Linden M, van Hees CL, van Beurden M, Bulten J, van Dorst EB, Esajas MD, Meeuwis KA, Boll D, van Poelgeest MI, de Hullu JA
Am J Obstet Gynecol 2022 Aug;227(2):250.e1-250.e8. Epub 2022 Apr 18 doi: 10.1016/j.ajog.2022.04.012. PMID: 35447145
Comparison of the biomarkers for targeted therapies in primary extra-mammary and mammary Paget's disease.
Gatalica Z, Vranic S, Krušlin B, Poorman K, Stafford P, Kacerovska D, Senarathne W, Florento E, Contreras E, Leary A, Choi A, In GK
Cancer Med 2020 Feb;9(4):1441-1450. Epub 2020 Jan 3 doi: 10.1002/cam4.2820. PMID: 31899853Free PMC Article
Interventions for the treatment of Paget's disease of the vulva.
Edey KA, Allan E, Murdoch JB, Cooper S, Bryant A
Cochrane Database Syst Rev 2013 Oct 26;(10):CD009245. doi: 10.1002/14651858.CD009245.pub2. PMID: 24163070
Effectiveness of photodynamic therapy for mammary and extra-mammary Paget's disease: a state of the science review.
Nardelli AA, Stafinski T, Menon D
BMC Dermatol 2011 Jun 15;11:13. doi: 10.1186/1471-5945-11-13. PMID: 21676258Free PMC Article

Prognosis

Glypican-3 Differentiates Intraductal Carcinoma and Paget's Disease from Other Types of Breast Cancer.
Alshammari FO, Satari AO, Aljabali AS, Al-Mahdy YS, Alabdallat YJ, Al-Sarayra YM, Alkhojah MA, Alwardat ARM, Haddad M, Al-Sarayreh SA, Al-Saraireh YM
Medicina (Kaunas) 2022 Dec 30;59(1) doi: 10.3390/medicina59010086. PMID: 36676710Free PMC Article
Treatment of Mammary Paget Disease: A systematic review and meta-analysis of real-world data.
Lin CW, Chiang MH, Tam KW
Int J Surg 2022 Nov;107:106964. Epub 2022 Oct 26 doi: 10.1016/j.ijsu.2022.106964. PMID: 36309195
More advantages in detecting bone and soft tissue metastases from prostate cancer using (18)F-PSMA PET/CT.
Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003
Skin diseases of the breast and nipple: Benign and malignant tumors.
Waldman RA, Finch J, Grant-Kels JM, Stevenson C, Whitaker-Worth D
J Am Acad Dermatol 2019 Jun;80(6):1467-1481. Epub 2018 Nov 16 doi: 10.1016/j.jaad.2018.08.066. PMID: 30452954
Mammary and extramammary Paget's disease.
Lopes Filho LL, Lopes IM, Lopes LR, Enokihara MM, Michalany AO, Matsunaga N
An Bras Dermatol 2015 Mar-Apr;90(2):225-31. doi: 10.1590/abd1806-4841.20153189. PMID: 25830993Free PMC Article

Clinical prediction guides

Treatment of Mammary Paget Disease: A systematic review and meta-analysis of real-world data.
Lin CW, Chiang MH, Tam KW
Int J Surg 2022 Nov;107:106964. Epub 2022 Oct 26 doi: 10.1016/j.ijsu.2022.106964. PMID: 36309195
The Paget Trial: topical 5% imiquimod cream for noninvasive vulvar Paget disease.
van der Linden M, van Hees CL, van Beurden M, Bulten J, van Dorst EB, Esajas MD, Meeuwis KA, Boll D, van Poelgeest MI, de Hullu JA
Am J Obstet Gynecol 2022 Aug;227(2):250.e1-250.e8. Epub 2022 Apr 18 doi: 10.1016/j.ajog.2022.04.012. PMID: 35447145
Nonsurgical Treatments for Extramammary Paget Disease: A Systematic Review and Meta-Analysis.
Snast I, Sharon E, Kaftory R, Noyman Y, Oren-Shabtai M, Lapidoth M, Hodak E, Mimouni D, Mazor S, Levi A
Dermatology 2020;236(6):493-499. Epub 2020 Apr 14 doi: 10.1159/000506832. PMID: 32289785
Comparison of the biomarkers for targeted therapies in primary extra-mammary and mammary Paget's disease.
Gatalica Z, Vranic S, Krušlin B, Poorman K, Stafford P, Kacerovska D, Senarathne W, Florento E, Contreras E, Leary A, Choi A, In GK
Cancer Med 2020 Feb;9(4):1441-1450. Epub 2020 Jan 3 doi: 10.1002/cam4.2820. PMID: 31899853Free PMC Article
More advantages in detecting bone and soft tissue metastases from prostate cancer using (18)F-PSMA PET/CT.
Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003

Recent systematic reviews

Treatment of Mammary Paget Disease: A systematic review and meta-analysis of real-world data.
Lin CW, Chiang MH, Tam KW
Int J Surg 2022 Nov;107:106964. Epub 2022 Oct 26 doi: 10.1016/j.ijsu.2022.106964. PMID: 36309195
Nonsurgical Treatments for Extramammary Paget Disease: A Systematic Review and Meta-Analysis.
Snast I, Sharon E, Kaftory R, Noyman Y, Oren-Shabtai M, Lapidoth M, Hodak E, Mimouni D, Mazor S, Levi A
Dermatology 2020;236(6):493-499. Epub 2020 Apr 14 doi: 10.1159/000506832. PMID: 32289785
Interventions for the treatment of Paget's disease of the vulva.
Edey KA, Allan E, Murdoch JB, Cooper S, Bryant A
Cochrane Database Syst Rev 2013 Oct 26;(10):CD009245. doi: 10.1002/14651858.CD009245.pub2. PMID: 24163070
Effectiveness of photodynamic therapy for mammary and extra-mammary Paget's disease: a state of the science review.
Nardelli AA, Stafinski T, Menon D
BMC Dermatol 2011 Jun 15;11:13. doi: 10.1186/1471-5945-11-13. PMID: 21676258Free PMC Article

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