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Resectable Digestive System Carcinoma

MedGen UID:
1668095
•Concept ID:
C4745161
•
Neoplastic Process

Definition

Digestive system carcinoma that is amenable to surgical resection. [from NCI]

Professional guidelines

PubMed

International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas.
Ohtsuka T, Fernandez-Del Castillo C, Furukawa T, Hijioka S, Jang JY, Lennon AM, Miyasaka Y, Ohno E, Salvia R, Wolfgang CL, Wood LD
Pancreatology 2024 Mar;24(2):255-270. Epub 2023 Dec 28 doi: 10.1016/j.pan.2023.12.009. PMID: 38182527
Clinical treatment of cholangiocarcinoma: an updated comprehensive review.
Elvevi A, Laffusa A, Scaravaglio M, Rossi RE, Longarini R, Stagno AM, Cristoferi L, Ciaccio A, Cortinovis DL, Invernizzi P, Massironi S
Ann Hepatol 2022 Sep-Oct;27(5):100737. Epub 2022 Jul 7 doi: 10.1016/j.aohep.2022.100737. PMID: 35809836
Appendiceal Mucinous Neoplasms: Diagnosis and Management.
Shaib WL, Assi R, Shamseddine A, Alese OB, Staley C 3rd, Memis B, Adsay V, Bekaii-Saab T, El-Rayes BF
Oncologist 2017 Sep;22(9):1107-1116. Epub 2017 Jun 29 doi: 10.1634/theoncologist.2017-0081. PMID: 28663356Free PMC Article

Recent clinical studies

Etiology

Current State and Future Directions of Radiation Therapy for Pancreas Adenocarcinoma.
Gottumukkala S, Salamekh S, Sanford NN
Surg Oncol Clin N Am 2023 Jul;32(3):399-414. Epub 2023 Apr 4 doi: 10.1016/j.soc.2023.02.001. PMID: 37182984
Role of surgery in pancreatic cancer.
Buanes TA
World J Gastroenterol 2017 Jun 7;23(21):3765-3770. doi: 10.3748/wjg.v23.i21.3765. PMID: 28638216Free PMC Article
Justifying vein resection with pancreatoduodenectomy.
Barreto SG, Windsor JA
Lancet Oncol 2016 Mar;17(3):e118-e124. Epub 2016 Mar 2 doi: 10.1016/S1470-2045(15)00463-5. PMID: 26972858
MRI of cholangiocarcinoma.
Jhaveri KS, Hosseini-Nik H
J Magn Reson Imaging 2015 Nov;42(5):1165-79. Epub 2014 Dec 1 doi: 10.1002/jmri.24810. PMID: 25447417
Distal biliary malignancy.
Veillette G, Castillo CF
Surg Clin North Am 2008 Dec;88(6):1429-47, xi. doi: 10.1016/j.suc.2008.07.003. PMID: 18992603

Diagnosis

Pancreatic Ductal Adenocarcinoma.
Dhillon J, Betancourt M
Monogr Clin Cytol 2020;26:74-91. Epub 2020 Sep 28 doi: 10.1159/000455736. PMID: 32987385
Pediatric Hepatocellular Carcinoma.
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
The diagnosis and treatment of cholangiocarcinoma.
Vogel A, Wege H, Caca K, Nashan B, Neumann U
Dtsch Arztebl Int 2014 Oct 31;111(44):748-54. doi: 10.3238/arztebl.2014.0748. PMID: 25412632Free PMC Article
Distal biliary malignancy.
Veillette G, Castillo CF
Surg Clin North Am 2008 Dec;88(6):1429-47, xi. doi: 10.1016/j.suc.2008.07.003. PMID: 18992603
Pancreatoblastoma.
Saif MW
JOP 2007 Jan 9;8(1):55-63. PMID: 17228135

Therapy

Efficacy of Preoperative mFOLFIRINOX vs mFOLFIRINOX Plus Hypofractionated Radiotherapy for Borderline Resectable Adenocarcinoma of the Pancreas: The A021501 Phase 2 Randomized Clinical Trial.
Katz MHG, Shi Q, Meyers J, Herman JM, Chuong M, Wolpin BM, Ahmad S, Marsh R, Schwartz L, Behr S, Frankel WL, Collisson E, Leenstra J, Williams TM, Vaccaro G, Venook A, Meyerhardt JA, O'Reilly EM
JAMA Oncol 2022 Sep 1;8(9):1263-1270. doi: 10.1001/jamaoncol.2022.2319. PMID: 35834226Free PMC Article
MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer.
Janjigian YY, Van Cutsem E, Muro K, Wainberg Z, Al-Batran SE, Hyung WJ, Molena D, Marcovitz M, Ruscica D, Robbins SH, Negro A, Tabernero J
Future Oncol 2022 Jun;18(20):2465-2473. Epub 2022 May 10 doi: 10.2217/fon-2022-0093. PMID: 35535555
Pediatric Hepatocellular Carcinoma.
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma.
Grossberg AJ, Chu LC, Deig CR, Fishman EK, Hwang WL, Maitra A, Marks DL, Mehta A, Nabavizadeh N, Simeone DM, Weekes CD, Thomas CR Jr
CA Cancer J Clin 2020 Sep;70(5):375-403. Epub 2020 Jul 19 doi: 10.3322/caac.21626. PMID: 32683683Free PMC Article
Endoscopic Management of Early Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus: Screening, Diagnosis, and Therapy.
di Pietro M, Canto MI, Fitzgerald RC
Gastroenterology 2018 Jan;154(2):421-436. Epub 2017 Aug 2 doi: 10.1053/j.gastro.2017.07.041. PMID: 28778650Free PMC Article

Prognosis

Surgical management of intrahepatic cholangiocarcinoma.
Hewitt DB, Brown ZJ, Pawlik TM
Expert Rev Anticancer Ther 2022 Jan;22(1):27-38. Epub 2021 Nov 15 doi: 10.1080/14737140.2022.1999809. PMID: 34730474
Pediatric Hepatocellular Carcinoma.
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Cholangiocellular Carcinoma.
Vogel A, Saborowski A
Digestion 2017;95(3):181-185. Epub 2017 Mar 14 doi: 10.1159/000454763. PMID: 28288474
Intrahepatic cholangiocarcinoma.
Poultsides GA, Zhu AX, Choti MA, Pawlik TM
Surg Clin North Am 2010 Aug;90(4):817-37. doi: 10.1016/j.suc.2010.04.011. PMID: 20637950
Distal biliary malignancy.
Veillette G, Castillo CF
Surg Clin North Am 2008 Dec;88(6):1429-47, xi. doi: 10.1016/j.suc.2008.07.003. PMID: 18992603

Clinical prediction guides

Survival benefit and impact of adjuvant chemotherapy following systemic neoadjuvant chemotherapy in patients with resected pancreas ductal adenocarcinoma: a retrospective cohort study.
Pu N, Wu W, Liu S, Xie Y, Yin H, Chen Q, He T, Xu Z, Wang W, Yu J, Liu L, Lou W
Int J Surg 2023 Oct 1;109(10):3137-3146. doi: 10.1097/JS9.0000000000000589. PMID: 37418574Free PMC Article
Surgery and hepatic artery infusion therapy for intrahepatic cholangiocarcinoma.
Scott A, Wong P, Melstrom LG
Surgery 2023 Jul;174(1):113-115. Epub 2023 Mar 9 doi: 10.1016/j.surg.2023.01.019. PMID: 36906437
Clinical and Histological Basis of Adenosquamous Carcinoma of the Pancreas: A 30-year Experience.
Moslim MA, Lefton MD, Ross EA, Mackrides N, Reddy SS
J Surg Res 2021 Mar;259:350-356. Epub 2020 Nov 13 doi: 10.1016/j.jss.2020.09.024. PMID: 33190924Free PMC Article
Operative management of cholangiocarcinoma.
Lee SY, Cherqui D
Semin Liver Dis 2013 Aug;33(3):248-61. Epub 2013 Aug 13 doi: 10.1055/s-0033-1351784. PMID: 23943105
Pathology of combined hepatocellular-cholangiocarcinoma.
Yeh MM
J Gastroenterol Hepatol 2010 Sep;25(9):1485-92. doi: 10.1111/j.1440-1746.2010.06430.x. PMID: 20796144

Recent systematic reviews

Comparative study on left-sided versus right-sided hepatectomy for resectable peri-hilar cholangiocarcinoma: a systematic review and meta-analysis.
Xu B, Zhao W, Chang J, Yin J, Wang N, Dong Z, Zhi X, Li T, Chen Z
World J Surg Oncol 2023 May 18;21(1):153. doi: 10.1186/s12957-023-03037-2. PMID: 37202795Free PMC Article
Major complications and mortality after resection of intrahepatic cholangiocarcinoma: A systematic review and meta-analysis.
van Keulen AM, Büttner S, Erdmann JI, Hagendoorn J, Hoogwater FJH, IJzermans JNM, Neumann UP, Polak WG, De Jonge J, Olthof PB, Koerkamp BG
Surgery 2023 Apr;173(4):973-982. Epub 2022 Dec 27 doi: 10.1016/j.surg.2022.11.027. PMID: 36577599
Liver Resection Versus Local Ablation Therapies for Hepatocellular Carcinoma Within the Milan Criteria: A Systematic Review and Meta-analysis.
Shin SW, Ahn KS, Kim SW, Kim TS, Kim YH, Kang KJ
Ann Surg 2021 Apr 1;273(4):656-666. doi: 10.1097/SLA.0000000000004350. PMID: 33074898
Stomach cancer.
Bailey C
BMJ Clin Evid 2011 Mar 28;2011 PMID: 21439098Free PMC Article
Stomach cancer.
Bailey C
BMJ Clin Evid 2008 Sep 3;2008 PMID: 19445803Free PMC Article

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