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Recurrent Urothelial Carcinoma

MedGen UID:
1676061
•Concept ID:
C4049507
•
Neoplastic Process
Synonyms: Recurrent Urothelial Cancer; Relapsed Urothelial Cancer; Relapsed Urothelial Carcinoma

Definition

The reemergence of urothelial carcinoma after a period of remission. [from NCI]

Professional guidelines

PubMed

Management of Oligometastatic and Locally Recurrent Urothelial Carcinoma.
Liu MA, Li JW, Runcie K
Curr Oncol Rep 2024 May;26(5):496-503. Epub 2024 Apr 11 doi: 10.1007/s11912-024-01523-8. PMID: 38602581
An evaluation of the real world use and clinical utility of the Cxbladder Monitor assay in the follow-up of patients previously treated for bladder cancer.
Koya M, Osborne S, Chemaslé C, Porten S, Schuckman A, Kennedy-Smith A
BMC Urol 2020 Feb 11;20(1):12. doi: 10.1186/s12894-020-0583-0. PMID: 32046687Free PMC Article
Managing noninvasive recurrences after definitive treatment for muscle-invasive bladder cancer or high-grade upper tract urothelial carcinoma.
DiBianco JM, George AK, Su D, Agarwal PK
Curr Opin Urol 2015 Sep;25(5):468-75. doi: 10.1097/MOU.0000000000000201. PMID: 26125507

Recent clinical studies

Etiology

Blue versus white light for transurethral resection of non-muscle invasive bladder cancer.
Maisch P, Koziarz A, Vajgrt J, Narayan V, Kim MH, Dahm P
Cochrane Database Syst Rev 2021 Dec 1;12(12):CD013776. doi: 10.1002/14651858.CD013776.pub2. PMID: 34850382Free PMC Article
Use of the Nuclear Matrix Protein 22 BladderChek Test for the Detection of Primary and Recurrent Urothelial Carcinoma.
Xia CS, Fan CH, Su M, Wang QS, Bao HZ
Dis Markers 2020;2020:3424039. Epub 2020 May 8 doi: 10.1155/2020/3424039. PMID: 32454904Free PMC Article
Programmed Death 1 and Programmed Death Ligand 1 Inhibitors in Advanced and Recurrent Urothelial Carcinoma: Meta-analysis of Single-Agent Studies.
Tafuri A, Smith DD, Cacciamani GE, Cole S, Shakir A, Sadeghi S, Vogelzang NJ, Quinn D, Gill PS, Gill IS
Clin Genitourin Cancer 2020 Oct;18(5):351-360.e3. Epub 2020 Jan 31 doi: 10.1016/j.clgc.2020.01.004. PMID: 32146152Free PMC Article
Radical cystectomy for recurrent urothelial carcinoma after prior partial cystectomy: perioperative and oncologic outcomes.
Mason RJ, Frank I, Bhindi B, Tollefson MK, Thompson RH, Karnes RJ, Tarrell R, Thapa P, Boorjian SA
World J Urol 2017 Dec;35(12):1879-1884. Epub 2017 Sep 14 doi: 10.1007/s00345-017-2087-4. PMID: 28913657
Cytohistologic correlation of recurrent urothelial carcinoma detected in urinary diversion specimens.
Xing J, Roy S, Monaco SE, Pantanowitz L
Cancer Cytopathol 2017 Feb;125(2):120-127. Epub 2016 Oct 14 doi: 10.1002/cncy.21786. PMID: 27741389

Diagnosis

Blue versus white light for transurethral resection of non-muscle invasive bladder cancer.
Maisch P, Koziarz A, Vajgrt J, Narayan V, Kim MH, Dahm P
Cochrane Database Syst Rev 2021 Dec 1;12(12):CD013776. doi: 10.1002/14651858.CD013776.pub2. PMID: 34850382Free PMC Article
Recurrent urothelial carcinoma-like FGFR3 genomic alterations in malignant Brenner tumors of the ovary.
Lin DI, Killian JK, Venstrom JM, Ramkissoon SH, Ross JS, Elvin JA
Mod Pathol 2021 May;34(5):983-993. Epub 2020 Oct 19 doi: 10.1038/s41379-020-00699-1. PMID: 33077920
Use of the Nuclear Matrix Protein 22 BladderChek Test for the Detection of Primary and Recurrent Urothelial Carcinoma.
Xia CS, Fan CH, Su M, Wang QS, Bao HZ
Dis Markers 2020;2020:3424039. Epub 2020 May 8 doi: 10.1155/2020/3424039. PMID: 32454904Free PMC Article
Cytohistologic correlation of recurrent urothelial carcinoma detected in urinary diversion specimens.
Xing J, Roy S, Monaco SE, Pantanowitz L
Cancer Cytopathol 2017 Feb;125(2):120-127. Epub 2016 Oct 14 doi: 10.1002/cncy.21786. PMID: 27741389
UroVysion® multiprobe FISH in the triage of equivocal urinary cytology cases.
Bubendorf L, Piaton E
Ann Pathol 2012 Dec;32(6):e52-6, 438-43. Epub 2012 Nov 24 doi: 10.1016/j.annpat.2012.09.207. PMID: 23244486

Therapy

Blue versus white light for transurethral resection of non-muscle invasive bladder cancer.
Maisch P, Koziarz A, Vajgrt J, Narayan V, Kim MH, Dahm P
Cochrane Database Syst Rev 2021 Dec 1;12(12):CD013776. doi: 10.1002/14651858.CD013776.pub2. PMID: 34850382Free PMC Article
Programmed Death 1 and Programmed Death Ligand 1 Inhibitors in Advanced and Recurrent Urothelial Carcinoma: Meta-analysis of Single-Agent Studies.
Tafuri A, Smith DD, Cacciamani GE, Cole S, Shakir A, Sadeghi S, Vogelzang NJ, Quinn D, Gill PS, Gill IS
Clin Genitourin Cancer 2020 Oct;18(5):351-360.e3. Epub 2020 Jan 31 doi: 10.1016/j.clgc.2020.01.004. PMID: 32146152Free PMC Article
Radical cystectomy for recurrent urothelial carcinoma after prior partial cystectomy: perioperative and oncologic outcomes.
Mason RJ, Frank I, Bhindi B, Tollefson MK, Thompson RH, Karnes RJ, Tarrell R, Thapa P, Boorjian SA
World J Urol 2017 Dec;35(12):1879-1884. Epub 2017 Sep 14 doi: 10.1007/s00345-017-2087-4. PMID: 28913657
Managing noninvasive recurrences after definitive treatment for muscle-invasive bladder cancer or high-grade upper tract urothelial carcinoma.
DiBianco JM, George AK, Su D, Agarwal PK
Curr Opin Urol 2015 Sep;25(5):468-75. doi: 10.1097/MOU.0000000000000201. PMID: 26125507
UroVysion® multiprobe FISH in the triage of equivocal urinary cytology cases.
Bubendorf L, Piaton E
Ann Pathol 2012 Dec;32(6):e52-6, 438-43. Epub 2012 Nov 24 doi: 10.1016/j.annpat.2012.09.207. PMID: 23244486

Prognosis

Management of Oligometastatic and Locally Recurrent Urothelial Carcinoma.
Liu MA, Li JW, Runcie K
Curr Oncol Rep 2024 May;26(5):496-503. Epub 2024 Apr 11 doi: 10.1007/s11912-024-01523-8. PMID: 38602581
Recurrent urothelial carcinoma-like FGFR3 genomic alterations in malignant Brenner tumors of the ovary.
Lin DI, Killian JK, Venstrom JM, Ramkissoon SH, Ross JS, Elvin JA
Mod Pathol 2021 May;34(5):983-993. Epub 2020 Oct 19 doi: 10.1038/s41379-020-00699-1. PMID: 33077920
Radical cystectomy for recurrent urothelial carcinoma after prior partial cystectomy: perioperative and oncologic outcomes.
Mason RJ, Frank I, Bhindi B, Tollefson MK, Thompson RH, Karnes RJ, Tarrell R, Thapa P, Boorjian SA
World J Urol 2017 Dec;35(12):1879-1884. Epub 2017 Sep 14 doi: 10.1007/s00345-017-2087-4. PMID: 28913657
Nomogram for predicting survival of postcystectomy recurrent urothelial carcinoma of the bladder.
Nakagawa T, Taguchi S, Uemura Y, Kanatani A, Ikeda M, Matsumoto A, Yoshida K, Kawai T, Nagata M, Yamada D, Komemushi Y, Suzuki M, Enomoto Y, Nishimatsu H, Ishikawa A, Nagase Y, Kondo Y, Tanaka Y, Okaneya T, Hirano Y, Shinohara M, Miyazaki H, Fujimura T, Fukuhara H, Kume H, Igawa Y, Homma Y
Urol Oncol 2017 Jul;35(7):457.e15-457.e21. Epub 2017 Jan 16 doi: 10.1016/j.urolonc.2016.12.010. PMID: 28110856
Managing noninvasive recurrences after definitive treatment for muscle-invasive bladder cancer or high-grade upper tract urothelial carcinoma.
DiBianco JM, George AK, Su D, Agarwal PK
Curr Opin Urol 2015 Sep;25(5):468-75. doi: 10.1097/MOU.0000000000000201. PMID: 26125507

Clinical prediction guides

Management of Oligometastatic and Locally Recurrent Urothelial Carcinoma.
Liu MA, Li JW, Runcie K
Curr Oncol Rep 2024 May;26(5):496-503. Epub 2024 Apr 11 doi: 10.1007/s11912-024-01523-8. PMID: 38602581
Assessing the impact of organ-specific lesion dynamics on survival in patients with recurrent urothelial carcinoma treated with atezolizumab or chemotherapy.
Kerioui M, Desmée S, Mercier F, Lin A, Wu B, Jin JY, Shen X, Le Tourneau C, Bruno R, Guedj J
ESMO Open 2022 Feb;7(1):100346. Epub 2021 Dec 23 doi: 10.1016/j.esmoop.2021.100346. PMID: 34954496Free PMC Article
Clinical comparison of noninvasive urine tests for ruling out recurrent urothelial carcinoma.
Lotan Y, OʼSullivan P, Raman JD, Shariat SF, Kavalieris L, Frampton C, Guilford P, Luxmanan C, Suttie J, Crist H, Scherr D, Asroff S, Goldfischer E, Thill J, Darling D
Urol Oncol 2017 Aug;35(8):531.e15-531.e22. Epub 2017 Mar 31 doi: 10.1016/j.urolonc.2017.03.008. PMID: 28366272
Nomogram for predicting survival of postcystectomy recurrent urothelial carcinoma of the bladder.
Nakagawa T, Taguchi S, Uemura Y, Kanatani A, Ikeda M, Matsumoto A, Yoshida K, Kawai T, Nagata M, Yamada D, Komemushi Y, Suzuki M, Enomoto Y, Nishimatsu H, Ishikawa A, Nagase Y, Kondo Y, Tanaka Y, Okaneya T, Hirano Y, Shinohara M, Miyazaki H, Fujimura T, Fukuhara H, Kume H, Igawa Y, Homma Y
Urol Oncol 2017 Jul;35(7):457.e15-457.e21. Epub 2017 Jan 16 doi: 10.1016/j.urolonc.2016.12.010. PMID: 28110856
Managing noninvasive recurrences after definitive treatment for muscle-invasive bladder cancer or high-grade upper tract urothelial carcinoma.
DiBianco JM, George AK, Su D, Agarwal PK
Curr Opin Urol 2015 Sep;25(5):468-75. doi: 10.1097/MOU.0000000000000201. PMID: 26125507

Recent systematic reviews

Blue versus white light for transurethral resection of non-muscle invasive bladder cancer.
Maisch P, Koziarz A, Vajgrt J, Narayan V, Kim MH, Dahm P
Cochrane Database Syst Rev 2021 Dec 1;12(12):CD013776. doi: 10.1002/14651858.CD013776.pub2. PMID: 34850382Free PMC Article
Programmed Death 1 and Programmed Death Ligand 1 Inhibitors in Advanced and Recurrent Urothelial Carcinoma: Meta-analysis of Single-Agent Studies.
Tafuri A, Smith DD, Cacciamani GE, Cole S, Shakir A, Sadeghi S, Vogelzang NJ, Quinn D, Gill PS, Gill IS
Clin Genitourin Cancer 2020 Oct;18(5):351-360.e3. Epub 2020 Jan 31 doi: 10.1016/j.clgc.2020.01.004. PMID: 32146152Free PMC Article

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