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Recurrent Endometrioid Adenocarcinoma

MedGen UID:
1681556
•Concept ID:
C0862493
•
Neoplastic Process
Synonyms: Recurrent Endometrial Adenocarcinoma; Recurrent Endometrial Adenocarcinoma, Not Otherwise Specified

Definition

The reemergence of endometrial adenocarcinoma after a period of remission. [from NCI]

Professional guidelines

PubMed

Evolving treatment paradigms in metastatic or recurrent low-grade endometrial cancer: When is hormonal-based therapy the preferred option?
Mahdi H, Ray-Coquard I, Lorusso D, Mirza MR, Monk BJ, Slomovitz B
Int J Gynecol Cancer 2023 Nov 6;33(11):1675-1681. doi: 10.1136/ijgc-2023-004454. PMID: 37640446Free PMC Article
PARP Inhibitors in the Management of Ovarian Cancer: ASCO Guideline.
Tew WP, Lacchetti C, Ellis A, Maxian K, Banerjee S, Bookman M, Jones MB, Lee JM, Lheureux S, Liu JF, Moore KN, Muller C, Rodriguez P, Walsh C, Westin SN, Kohn EC
J Clin Oncol 2020 Oct 20;38(30):3468-3493. Epub 2020 Aug 13 doi: 10.1200/JCO.20.01924. PMID: 32790492Free PMC Article
Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer-Combined Analysis of the PORTEC Cohorts.
Stelloo E, Nout RA, Osse EM, Jürgenliemk-Schulz IJ, Jobsen JJ, Lutgens LC, van der Steen-Banasik EM, Nijman HW, Putter H, Bosse T, Creutzberg CL, Smit VT
Clin Cancer Res 2016 Aug 15;22(16):4215-24. Epub 2016 Mar 22 doi: 10.1158/1078-0432.CCR-15-2878. PMID: 27006490

Recent clinical studies

Therapy

Phase 2 trial of mifepristone (RU-486) in advanced or recurrent endometrioid adenocarcinoma or low-grade endometrial stromal sarcoma.
Ramondetta LM, Johnson AJ, Sun CC, Atkinson N, Smith JA, Jung MS, Broaddus R, Iyer RB, Burke T
Cancer 2009 May 1;115(9):1867-74. doi: 10.1002/cncr.24197. PMID: 19241422

Prognosis

Cushing's syndrome associated with recurrent endometrioid adenocarcinoma of the ovary.
Crawford SM, Pyrah RD, Ismail SM
J Clin Pathol 1994 Aug;47(8):766-8. doi: 10.1136/jcp.47.8.766. PMID: 7962637Free PMC Article

Clinical prediction guides

Phase 2 trial of mifepristone (RU-486) in advanced or recurrent endometrioid adenocarcinoma or low-grade endometrial stromal sarcoma.
Ramondetta LM, Johnson AJ, Sun CC, Atkinson N, Smith JA, Jung MS, Broaddus R, Iyer RB, Burke T
Cancer 2009 May 1;115(9):1867-74. doi: 10.1002/cncr.24197. PMID: 19241422

Supplemental Content

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