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Chronic Ocular Graft Versus Host Disease

MedGen UID:
1685703
•Concept ID:
C5203918
•
Disease or Syndrome

Definition

Chronic graft versus host disease occurring in the eye. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic Ocular Graft Versus Host Disease

Professional guidelines

PubMed

Safety and efficacy of intense pulsed light in the treatment of severe chronic ocular graft-versus-host disease.
Wang H, Yin X, Li Y, Zhang Z, Zhao K, Hu F, Liu Q, Lu Q, Wang Y, Zhang L, Jia H, Han J, Guo J, Li M
Ocul Surf 2023 Oct;30:276-285. Epub 2023 Oct 7 doi: 10.1016/j.jtos.2023.10.002. PMID: 37813151
Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria.
Ogawa Y, Dana R, Kim S, Jain S, Rosenblatt MI, Perez VL, Clayton JA, Alves M, Rocha EM, Amparo F, Seo KY, Wang Y, Shen J, Oh JY, Vanathi M, Nair S, Na KS, Riemens A, Sippel K, Soifer M, Wang S, Trindade M, Kim MK, Yoon CH, Yagi R, Hiratsuka R, Ogawa M, Shimizu E, Sato Y, Pflugfelder S, Tsubota K
Ocul Surf 2022 Oct;26:200-208. Epub 2022 Sep 18 doi: 10.1016/j.jtos.2022.09.002. PMID: 36130695
Lifitegrast ophthalmic solution for treatment of ocular chronic graft-versus-host disease.
Chhabra S, Jerkins JH, Conto JE, Zellner K, Shah NN, Hari PN, Hamadani M
Leuk Lymphoma 2020 Apr;61(4):869-874. Epub 2019 Nov 25 doi: 10.1080/10428194.2019.1695049. PMID: 31762357

Recent clinical studies

Etiology

Alteration of Meibum Lipidomics Profiling in Patients With Chronic Ocular Graft-Versus-Host Disease.
Zhao W, Yang J, Liao Y, Yang B, Lin S, Liu R, Liang L
Invest Ophthalmol Vis Sci 2023 Sep 1;64(12):35. doi: 10.1167/iovs.64.12.35. PMID: 37733365Free PMC Article
Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease.
Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P
Transplant Cell Ther 2022 Nov;28(11):782.e1-782.e7. Epub 2022 Jul 31 doi: 10.1016/j.jtct.2022.07.027. PMID: 35921986
Biomarkers in Ocular Graft-Versus-Host Disease: Implications for the Involvement of B Cells.
Shen Z, Ma J, Peng R, Hu B, Zhao Y, Liu S, Hong J
Transplant Cell Ther 2022 Nov;28(11):749.e1-749.e7. Epub 2022 Jul 29 doi: 10.1016/j.jtct.2022.07.023. PMID: 35914728
Prevalence of neurotrophic keratopathy in patients with chronic ocular graft-versus-host disease.
Singh RB, Yuksel E, Sinha S, Wang S, Taketani Y, Luznik Z, Yin J, Dohlman TH, Dana R
Ocul Surf 2022 Oct;26:13-18. Epub 2022 Jul 16 doi: 10.1016/j.jtos.2022.07.001. PMID: 35843560
Ocular surface indicators and biomarkers in chronic ocular graft-versus-host disease: a prospective cohort study.
Pietraszkiewicz AA, Payne D, Abraham M, Garced A, Devarasetty KC, Wall M, Menezes SM, Ugarte S, Pirsl F, Goklemez S, Ferris FL, Barrett J, Battiwalla M, Childs RW, Pavletic SZ, Bishop RJ
Bone Marrow Transplant 2021 Aug;56(8):1850-1858. Epub 2021 Mar 8 doi: 10.1038/s41409-021-01254-5. PMID: 33686249Free PMC Article

Diagnosis

Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria.
Ogawa Y, Dana R, Kim S, Jain S, Rosenblatt MI, Perez VL, Clayton JA, Alves M, Rocha EM, Amparo F, Seo KY, Wang Y, Shen J, Oh JY, Vanathi M, Nair S, Na KS, Riemens A, Sippel K, Soifer M, Wang S, Trindade M, Kim MK, Yoon CH, Yagi R, Hiratsuka R, Ogawa M, Shimizu E, Sato Y, Pflugfelder S, Tsubota K
Ocul Surf 2022 Oct;26:200-208. Epub 2022 Sep 18 doi: 10.1016/j.jtos.2022.09.002. PMID: 36130695
Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease.
Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P
Transplant Cell Ther 2022 Nov;28(11):782.e1-782.e7. Epub 2022 Jul 31 doi: 10.1016/j.jtct.2022.07.027. PMID: 35921986
Biomarkers in Ocular Graft-Versus-Host Disease: Implications for the Involvement of B Cells.
Shen Z, Ma J, Peng R, Hu B, Zhao Y, Liu S, Hong J
Transplant Cell Ther 2022 Nov;28(11):749.e1-749.e7. Epub 2022 Jul 29 doi: 10.1016/j.jtct.2022.07.023. PMID: 35914728
Prevalence of neurotrophic keratopathy in patients with chronic ocular graft-versus-host disease.
Singh RB, Yuksel E, Sinha S, Wang S, Taketani Y, Luznik Z, Yin J, Dohlman TH, Dana R
Ocul Surf 2022 Oct;26:13-18. Epub 2022 Jul 16 doi: 10.1016/j.jtos.2022.07.001. PMID: 35843560
Update on ocular graft versus host disease.
Kim SK
Curr Opin Ophthalmol 2006 Aug;17(4):344-8. doi: 10.1097/01.icu.0000233952.09595.d8. PMID: 16900025

Therapy

Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria.
Ogawa Y, Dana R, Kim S, Jain S, Rosenblatt MI, Perez VL, Clayton JA, Alves M, Rocha EM, Amparo F, Seo KY, Wang Y, Shen J, Oh JY, Vanathi M, Nair S, Na KS, Riemens A, Sippel K, Soifer M, Wang S, Trindade M, Kim MK, Yoon CH, Yagi R, Hiratsuka R, Ogawa M, Shimizu E, Sato Y, Pflugfelder S, Tsubota K
Ocul Surf 2022 Oct;26:200-208. Epub 2022 Sep 18 doi: 10.1016/j.jtos.2022.09.002. PMID: 36130695
Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease.
Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P
Transplant Cell Ther 2022 Nov;28(11):782.e1-782.e7. Epub 2022 Jul 31 doi: 10.1016/j.jtct.2022.07.027. PMID: 35921986
Prevalence of neurotrophic keratopathy in patients with chronic ocular graft-versus-host disease.
Singh RB, Yuksel E, Sinha S, Wang S, Taketani Y, Luznik Z, Yin J, Dohlman TH, Dana R
Ocul Surf 2022 Oct;26:13-18. Epub 2022 Jul 16 doi: 10.1016/j.jtos.2022.07.001. PMID: 35843560
Prevalence and Risk Factors Associated With Corneal Perforation in Chronic Ocular Graft-Versus-Host-Disease.
Sinha S, Singh RB, Dohlman TH, Taketani Y, Yin J, Dana R
Cornea 2021 Jul 1;40(7):877-882. doi: 10.1097/ICO.0000000000002526. PMID: 32947414
Update on ocular graft versus host disease.
Kim SK
Curr Opin Ophthalmol 2006 Aug;17(4):344-8. doi: 10.1097/01.icu.0000233952.09595.d8. PMID: 16900025

Prognosis

Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria.
Ogawa Y, Dana R, Kim S, Jain S, Rosenblatt MI, Perez VL, Clayton JA, Alves M, Rocha EM, Amparo F, Seo KY, Wang Y, Shen J, Oh JY, Vanathi M, Nair S, Na KS, Riemens A, Sippel K, Soifer M, Wang S, Trindade M, Kim MK, Yoon CH, Yagi R, Hiratsuka R, Ogawa M, Shimizu E, Sato Y, Pflugfelder S, Tsubota K
Ocul Surf 2022 Oct;26:200-208. Epub 2022 Sep 18 doi: 10.1016/j.jtos.2022.09.002. PMID: 36130695
Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease.
Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P
Transplant Cell Ther 2022 Nov;28(11):782.e1-782.e7. Epub 2022 Jul 31 doi: 10.1016/j.jtct.2022.07.027. PMID: 35921986
Biomarkers in Ocular Graft-Versus-Host Disease: Implications for the Involvement of B Cells.
Shen Z, Ma J, Peng R, Hu B, Zhao Y, Liu S, Hong J
Transplant Cell Ther 2022 Nov;28(11):749.e1-749.e7. Epub 2022 Jul 29 doi: 10.1016/j.jtct.2022.07.023. PMID: 35914728
Long-term clinical outcomes and predictive factors in patients with chronic ocular graft-versus-host disease.
Yoon HJ, Song GY, Yoon KC
Sci Rep 2022 Jul 29;12(1):12985. doi: 10.1038/s41598-022-17032-2. PMID: 35906359Free PMC Article
Eyelid metrics assessment in patients with chronic ocular graft versus-host disease.
Giannaccare G, Bernabei F, Pellegrini M, Arpinati M, Bonifazi F, Sessa M, Versura P, Campos E
Ocul Surf 2019 Jan;17(1):98-103. Epub 2018 Oct 12 doi: 10.1016/j.jtos.2018.10.005. PMID: 30321606

Clinical prediction guides

Tear Cytokines Associated With Therapeutic Effects in Chronic Ocular Graft-Versus-Host Disease.
Ma J, Shen Z, Peng R, Li C, Zhao Y, Hu B, Hong J
Cornea 2023 Feb 1;42(2):211-216. Epub 2022 Jul 4 doi: 10.1097/ICO.0000000000003081. PMID: 36582034
Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease.
Gehlsen U, Stern ME, Franklin J, Tahmaz V, Hallek M, Holtick U, Scheid C, Steven P
Transplant Cell Ther 2022 Nov;28(11):782.e1-782.e7. Epub 2022 Jul 31 doi: 10.1016/j.jtct.2022.07.027. PMID: 35921986
Biomarkers in Ocular Graft-Versus-Host Disease: Implications for the Involvement of B Cells.
Shen Z, Ma J, Peng R, Hu B, Zhao Y, Liu S, Hong J
Transplant Cell Ther 2022 Nov;28(11):749.e1-749.e7. Epub 2022 Jul 29 doi: 10.1016/j.jtct.2022.07.023. PMID: 35914728
Long-term clinical outcomes and predictive factors in patients with chronic ocular graft-versus-host disease.
Yoon HJ, Song GY, Yoon KC
Sci Rep 2022 Jul 29;12(1):12985. doi: 10.1038/s41598-022-17032-2. PMID: 35906359Free PMC Article
Prevalence of neurotrophic keratopathy in patients with chronic ocular graft-versus-host disease.
Singh RB, Yuksel E, Sinha S, Wang S, Taketani Y, Luznik Z, Yin J, Dohlman TH, Dana R
Ocul Surf 2022 Oct;26:13-18. Epub 2022 Jul 16 doi: 10.1016/j.jtos.2022.07.001. PMID: 35843560

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