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Cervical Cancer by FIGO Stage 2018

MedGen UID:
1706227
•Concept ID:
C5207005
•
Neoplastic Process
Synonym: Cervical Carcinoma by FIGO Stage 2018

Definition

A term that refers to the staging of cervical cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging, 2018. [from NCI]

Professional guidelines

PubMed

Optimal treatment in locally advanced cervical cancer.
Gennigens C, De Cuypere M, Hermesse J, Kridelka F, Jerusalem G
Expert Rev Anticancer Ther 2021 Jun;21(6):657-671. Epub 2021 Mar 11 doi: 10.1080/14737140.2021.1879646. PMID: 33472018
What Is the Role of Imaging at Primary Diagnostic Work-Up in Uterine Cervical Cancer?
Haldorsen IS, Lura N, Blaakær J, Fischerova D, Werner HMJ
Curr Oncol Rep 2019 Jul 29;21(9):77. doi: 10.1007/s11912-019-0824-0. PMID: 31359169Free PMC Article
Chemotherapy and targeted therapy in the management of cervical cancer.
Kumar L, Harish P, Malik PS, Khurana S
Curr Probl Cancer 2018 Mar-Apr;42(2):120-128. Epub 2018 Feb 3 doi: 10.1016/j.currproblcancer.2018.01.016. PMID: 29530393

Recent clinical studies

Etiology

Cancer of the cervix uteri: 2021 update.
Bhatla N, Aoki D, Sharma DN, Sankaranarayanan R
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):28-44. doi: 10.1002/ijgo.13865. PMID: 34669203Free PMC Article
Optimal treatment in locally advanced cervical cancer.
Gennigens C, De Cuypere M, Hermesse J, Kridelka F, Jerusalem G
Expert Rev Anticancer Ther 2021 Jun;21(6):657-671. Epub 2021 Mar 11 doi: 10.1080/14737140.2021.1879646. PMID: 33472018
Effectiveness of Sequential Chemoradiation vs Concurrent Chemoradiation or Radiation Alone in Adjuvant Treatment After Hysterectomy for Cervical Cancer: The STARS Phase 3 Randomized Clinical Trial.
Huang H, Feng YL, Wan T, Zhang YN, Cao XP, Huang YW, Xiong Y, Huang X, Zheng M, Li YF, Li JD, Chen GD, Li H, Chen YL, Ma LG, Yang HY, Li L, Yao SZ, Ye WJ, Tu H, Huang QD, Liang LZ, Liu FY, Liu Q, Liu JH
JAMA Oncol 2021 Mar 1;7(3):361-369. doi: 10.1001/jamaoncol.2020.7168. PMID: 33443541Free PMC Article
What Is the Role of Imaging at Primary Diagnostic Work-Up in Uterine Cervical Cancer?
Haldorsen IS, Lura N, Blaakær J, Fischerova D, Werner HMJ
Curr Oncol Rep 2019 Jul 29;21(9):77. doi: 10.1007/s11912-019-0824-0. PMID: 31359169Free PMC Article
Validation of the 2018 FIGO cervical cancer staging system.
Matsuo K, Machida H, Mandelbaum RS, Konishi I, Mikami M
Gynecol Oncol 2019 Jan;152(1):87-93. Epub 2018 Oct 30 doi: 10.1016/j.ygyno.2018.10.026. PMID: 30389105Free PMC Article

Diagnosis

Cervical cancer in the pregnant population.
Nguyen T, Nougaret S, Castillo P, Paspulati R, Bhosale P
Abdom Radiol (NY) 2023 May;48(5):1679-1693. Epub 2023 Apr 18 doi: 10.1007/s00261-023-03836-x. PMID: 37071123
Cancer of the cervix uteri: 2021 update.
Bhatla N, Aoki D, Sharma DN, Sankaranarayanan R
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):28-44. doi: 10.1002/ijgo.13865. PMID: 34669203Free PMC Article
Revised FIGO Staging for Cervical Cancer - A New Role for MRI.
Merz J, Bossart M, Bamberg F, Eisenblaetter M
Rofo 2020 Oct;192(10):937-944. Epub 2020 Jul 30 doi: 10.1055/a-1198-5729. PMID: 32731266
What Is the Role of Imaging at Primary Diagnostic Work-Up in Uterine Cervical Cancer?
Haldorsen IS, Lura N, Blaakær J, Fischerova D, Werner HMJ
Curr Oncol Rep 2019 Jul 29;21(9):77. doi: 10.1007/s11912-019-0824-0. PMID: 31359169Free PMC Article
Cancer of the cervix uteri.
Bhatla N, Aoki D, Sharma DN, Sankaranarayanan R
Int J Gynaecol Obstet 2018 Oct;143 Suppl 2:22-36. doi: 10.1002/ijgo.12611. PMID: 30306584

Therapy

Infiltration by Intratumor and Stromal CD8 and CD68 in Cervical Cancer.
Dimitrova P, Vasileva-Slaveva M, Shivarov V, Hasan I, Yordanov A
Medicina (Kaunas) 2023 Apr 7;59(4) doi: 10.3390/medicina59040728. PMID: 37109686Free PMC Article
Debulking hysterectomy followed by chemoradiotherapy versus chemoradiotherapy for FIGO stage (2019) IB3/II cervical cancer.
Chakrabarti M, Nordin A, Khodabocus J
Cochrane Database Syst Rev 2022 Sep 16;9(9):CD012246. doi: 10.1002/14651858.CD012246.pub2. PMID: 36111784Free PMC Article
Effectiveness of Sequential Chemoradiation vs Concurrent Chemoradiation or Radiation Alone in Adjuvant Treatment After Hysterectomy for Cervical Cancer: The STARS Phase 3 Randomized Clinical Trial.
Huang H, Feng YL, Wan T, Zhang YN, Cao XP, Huang YW, Xiong Y, Huang X, Zheng M, Li YF, Li JD, Chen GD, Li H, Chen YL, Ma LG, Yang HY, Li L, Yao SZ, Ye WJ, Tu H, Huang QD, Liang LZ, Liu FY, Liu Q, Liu JH
JAMA Oncol 2021 Mar 1;7(3):361-369. doi: 10.1001/jamaoncol.2020.7168. PMID: 33443541Free PMC Article
The management of locally advanced cervical cancer.
Naga Ch P, Gurram L, Chopra S, Mahantshetty U
Curr Opin Oncol 2018 Sep;30(5):323-329. doi: 10.1097/CCO.0000000000000471. PMID: 29994902
Chemotherapy and targeted therapy in the management of cervical cancer.
Kumar L, Harish P, Malik PS, Khurana S
Curr Probl Cancer 2018 Mar-Apr;42(2):120-128. Epub 2018 Feb 3 doi: 10.1016/j.currproblcancer.2018.01.016. PMID: 29530393

Prognosis

Staging, recurrence and follow-up of uterine cervical cancer using MRI: Updated Guidelines of the European Society of Urogenital Radiology after revised FIGO staging 2018.
Manganaro L, Lakhman Y, Bharwani N, Gui B, Gigli S, Vinci V, Rizzo S, Kido A, Cunha TM, Sala E, Rockall A, Forstner R, Nougaret S
Eur Radiol 2021 Oct;31(10):7802-7816. Epub 2021 Apr 14 doi: 10.1007/s00330-020-07632-9. PMID: 33852049
Optimal treatment in locally advanced cervical cancer.
Gennigens C, De Cuypere M, Hermesse J, Kridelka F, Jerusalem G
Expert Rev Anticancer Ther 2021 Jun;21(6):657-671. Epub 2021 Mar 11 doi: 10.1080/14737140.2021.1879646. PMID: 33472018
2018 FIGO Staging Classification for Cervical Cancer: Added Benefits of Imaging.
Salib MY, Russell JHB, Stewart VR, Sudderuddin SA, Barwick TD, Rockall AG, Bharwani N
Radiographics 2020 Oct;40(6):1807-1822. Epub 2020 Sep 18 doi: 10.1148/rg.2020200013. PMID: 32946322
Revised FIGO Staging for Cervical Cancer - A New Role for MRI.
Merz J, Bossart M, Bamberg F, Eisenblaetter M
Rofo 2020 Oct;192(10):937-944. Epub 2020 Jul 30 doi: 10.1055/a-1198-5729. PMID: 32731266
Cervical Cancer: 2018 Revised International Federation of Gynecology and Obstetrics Staging System and the Role of Imaging.
Saleh M, Virarkar M, Javadi S, Elsherif SB, de Castro Faria S, Bhosale P
AJR Am J Roentgenol 2020 May;214(5):1182-1195. Epub 2020 Mar 17 doi: 10.2214/AJR.19.21819. PMID: 32182097

Clinical prediction guides

Visceral fat percentage for prediction of outcome in uterine cervical cancer.
Eide AJ, Halle MK, Lura N, Fasmer KE, Wagner-Larsen K, Forsse D, Bertelsen BI, Salvesen Ø, Krakstad C, Haldorsen IS
Gynecol Oncol 2023 Sep;176:62-68. Epub 2023 Jul 13 doi: 10.1016/j.ygyno.2023.06.581. PMID: 37453220
Multicentric development and evaluation of (18)F-FDG PET/CT and MRI radiomics models to predict para-aortic lymph node involvement in locally advanced cervical cancer.
Lucia F, Bourbonne V, Pleyers C, Dupré PF, Miranda O, Visvikis D, Pradier O, Abgral R, Mervoyer A, Classe JM, Rousseau C, Vos W, Hermesse J, Gennigens C, De Cuypere M, Kridelka F, Schick U, Hatt M, Hustinx R, Lovinfosse P
Eur J Nucl Med Mol Imaging 2023 Jul;50(8):2514-2528. Epub 2023 Mar 9 doi: 10.1007/s00259-023-06180-w. PMID: 36892667
Overall survival in patients with FIGO stage IVA cervical cancer.
Schiff JP, Mintz R, Cohen AC, Huang Y, Thaker P, Massad LS, Powell M, Mutch D, Schwarz JK, Markovina ST, Grigsby PW
Gynecol Oncol 2022 Aug;166(2):292-299. Epub 2022 Jun 10 doi: 10.1016/j.ygyno.2022.05.022. PMID: 35691754
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Implications of the new FIGO staging and the role of imaging in cervical cancer.
Kido A, Nakamoto Y
Br J Radiol 2021 Sep 1;94(1125):20201342. Epub 2021 May 14 doi: 10.1259/bjr.20201342. PMID: 33989030Free PMC Article

Recent systematic reviews

Definitive pelvic radiotherapy for patients with newly diagnosed stage IVB cervical cancer: a systematic review.
Viveros-Carreño D, Vieira-Serna S, Grillo-Ardila CF, Rodriguez J, Mora-Soto N, Jhingran A, Ramirez PT, Pareja R
Int J Gynecol Cancer 2023 Jul 3;33(7):1057-1062. doi: 10.1136/ijgc-2023-004465. PMID: 37192760
Debulking hysterectomy followed by chemoradiotherapy versus chemoradiotherapy for FIGO stage (2019) IB3/II cervical cancer.
Chakrabarti M, Nordin A, Khodabocus J
Cochrane Database Syst Rev 2022 Sep 16;9(9):CD012246. doi: 10.1002/14651858.CD012246.pub2. PMID: 36111784Free PMC Article
Fertility-sparing surgery after neo-adjuvant chemotherapy in women with cervical cancer larger than 4 cm: a systematic review.
Viveros-Carreño D, Rodriguez J, Rendon Pereira GJ, Slama J, Halaska MJ, Robova H, Pareja R
Int J Gynecol Cancer 2022 Apr 4;32(4):486-493. doi: 10.1136/ijgc-2021-003297. PMID: 35210296
Abdominal radical trachelectomy versus chemotherapy followed by vaginal radical trachelectomy in stage 1B2 (FIGO 2018) cervical cancer. A systematic review on fertility and recurrence rates.
van Kol KGG, Vergeldt TFM, Bekkers RLM
Gynecol Oncol 2019 Dec;155(3):515-521. Epub 2019 Oct 9 doi: 10.1016/j.ygyno.2019.09.025. PMID: 31606284
Influence of clinicopathological characteristics and comprehensive treatment models on the prognosis of small cell carcinoma of the cervix: A systematic review and meta-analysis.
Zhang Q, Xiong Y, Ye J, Zhang L, Li L
PLoS One 2018;13(4):e0192784. Epub 2018 Apr 11 doi: 10.1371/journal.pone.0192784. PMID: 29641578Free PMC Article

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