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Decreased adipose tissue tocopherol level

MedGen UID:
1713546
•Concept ID:
C5397672
•
Finding
HPO: HP:0032655

Definition

A reduced concentration of tocopherol in fat tissue. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased adipose tissue tocopherol level

Recent clinical studies

Etiology

Effects of diets high in animal or plant protein on oxidative stress in individuals with type 2 diabetes: A randomized clinical trial.
Pivovarova-Ramich O, Markova M, Weber D, Sucher S, Hornemann S, Rudovich N, Raila J, Sunaga-Franze D, Sauer S, Rohn S, Pfeiffer AFH, Grune T
Redox Biol 2020 Jan;29:101397. Epub 2019 Nov 28 doi: 10.1016/j.redox.2019.101397. PMID: 31926623Free PMC Article
Oxidant mechanisms in childhood obesity: the link between inflammation and oxidative stress.
Codoñer-Franch P, Valls-Bellés V, Arilla-Codoñer A, Alonso-Iglesias E
Transl Res 2011 Dec;158(6):369-84. Epub 2011 Sep 3 doi: 10.1016/j.trsl.2011.08.004. PMID: 22061044
Effects of dietary n-3 polyunsaturated fatty acids, breed and dietary vitamin E on the fatty acids of lamb muscle, liver and adipose tissue.
Demirel G, Wachira AM, Sinclair LA, Wilkinson RG, Wood JD, Enser M
Br J Nutr 2004 Apr;91(4):551-65. doi: 10.1079/BJN20031079. PMID: 15035682
Vitamin C nutriture has little short-term effect on vitamin E concentrations in healthy women.
Jacob RA, Kutnink MA, Csallany AS, Daroszewska M, Burton GW
J Nutr 1996 Sep;126(9):2268-77. doi: 10.1093/jn/126.9.2268. PMID: 8814216
Fatty acid composition of adipose tissue and serum micronutrients in relation to common rheumatic complaints in Swedish adults 50-70 years old.
Jacobsson L, Lindgärde F, Manthorpe R, Akesson B
Scand J Rheumatol 1992;21(4):171-7. doi: 10.3109/03009749209099217. PMID: 1529283

Diagnosis

Modifications of alpha-tocopherol and fatty acid concentrations in blood and adipose tissue of obese patients during a weight loss programme.
Bonnefont-Rousselot D, Lepage S, Thérond P, Bastard JP, Hainque B, Turpin G, Legrand A, Delattre J, Bruckert E
Nutr Metab Cardiovasc Dis 1999 Feb;9(1):25-32. PMID: 10726106

Therapy

Effects of diets high in animal or plant protein on oxidative stress in individuals with type 2 diabetes: A randomized clinical trial.
Pivovarova-Ramich O, Markova M, Weber D, Sucher S, Hornemann S, Rudovich N, Raila J, Sunaga-Franze D, Sauer S, Rohn S, Pfeiffer AFH, Grune T
Redox Biol 2020 Jan;29:101397. Epub 2019 Nov 28 doi: 10.1016/j.redox.2019.101397. PMID: 31926623Free PMC Article
α-Tocopherol Attenuates the Triglyceride- and Cholesterol-Lowering Effects of Rice Bran Tocotrienol in Rats Fed a Western Diet.
Shibata A, Kawakami Y, Kimura T, Miyazawa T, Nakagawa K
J Agric Food Chem 2016 Jul 6;64(26):5361-6. Epub 2016 Jun 21 doi: 10.1021/acs.jafc.6b02228. PMID: 27295311
Modifications of alpha-tocopherol and fatty acid concentrations in blood and adipose tissue of obese patients during a weight loss programme.
Bonnefont-Rousselot D, Lepage S, Thérond P, Bastard JP, Hainque B, Turpin G, Legrand A, Delattre J, Bruckert E
Nutr Metab Cardiovasc Dis 1999 Feb;9(1):25-32. PMID: 10726106
Vitamin C nutriture has little short-term effect on vitamin E concentrations in healthy women.
Jacob RA, Kutnink MA, Csallany AS, Daroszewska M, Burton GW
J Nutr 1996 Sep;126(9):2268-77. doi: 10.1093/jn/126.9.2268. PMID: 8814216
Fatty acid composition of adipose tissue and serum micronutrients in relation to common rheumatic complaints in Swedish adults 50-70 years old.
Jacobsson L, Lindgärde F, Manthorpe R, Akesson B
Scand J Rheumatol 1992;21(4):171-7. doi: 10.3109/03009749209099217. PMID: 1529283

Clinical prediction guides

Metabolite Changes After Metabolic Surgery - Associations to Parameters Reflecting Glucose Homeostasis and Lipid Levels.
Ahlin S, Cefalo C, Bondia-Pons I, Trošt K, Capristo E, Marini L, Romero M, Zorzano A, Gastaldelli A, Mingrone G, Nolan JJ
Front Endocrinol (Lausanne) 2021;12:786952. Epub 2021 Dec 16 doi: 10.3389/fendo.2021.786952. PMID: 34975758Free PMC Article
Modifications of alpha-tocopherol and fatty acid concentrations in blood and adipose tissue of obese patients during a weight loss programme.
Bonnefont-Rousselot D, Lepage S, Thérond P, Bastard JP, Hainque B, Turpin G, Legrand A, Delattre J, Bruckert E
Nutr Metab Cardiovasc Dis 1999 Feb;9(1):25-32. PMID: 10726106
Tissue antioxidants and postmenopausal breast cancer: the European Community Multicentre Study on Antioxidants, Myocardial Infarction, and Cancer of the Breast (EURAMIC).
van 't Veer P, Strain JJ, Fernandez-Crehuet J, Martin BC, Thamm M, Kardinaal AF, Kohlmeier L, Huttunen JK, Martin-Moreno JM, Kok FJ
Cancer Epidemiol Biomarkers Prev 1996 Jun;5(6):441-7. PMID: 8781740

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