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Renal interstitial xanthogranulomatous inflammation

MedGen UID:
1716614
•Concept ID:
C5397663
•
Pathologic Function
HPO: HP:0032646

Definition

Inflammation of interstitial tissues of the kidney consisting of foamy macrophages admixed with plasma cells, lymphocytes and neutrophils and occasional giant cells. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRenal interstitial xanthogranulomatous inflammation

Recent clinical studies

Etiology

Granulomatous interstitial nephritis: a clinicopathologic study of 46 cases from a single institution.
Bijol V, Mendez GP, Nosé V, Rennke HG
Int J Surg Pathol 2006 Jan;14(1):57-63. doi: 10.1177/106689690601400110. PMID: 16501836

Diagnosis

Xanthogranulomatous pyelonephritis is associated with higher tissue expression of monocyte chemotactic protein-1.
Bartoli F, Gesualdo L, Niglio F, Gentile O, Penza R, Leggio S, Lasalandra C, Campanella V, Magaldi S
Eur J Pediatr Surg 2007 Oct;17(5):365-9. doi: 10.1055/s-2007-965534. PMID: 17968796

Therapy

Granulomatous interstitial nephritis: a clinicopathologic study of 46 cases from a single institution.
Bijol V, Mendez GP, Nosé V, Rennke HG
Int J Surg Pathol 2006 Jan;14(1):57-63. doi: 10.1177/106689690601400110. PMID: 16501836

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