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Locally Advanced Adenocarcinoma

MedGen UID:
1718547
Concept ID:
C5239285
Neoplastic Process

Definition

Adenocarcinoma that has spread to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Adenocarcinoma

Professional guidelines

PubMed

Bouckaert A, Moons J, Lerut T, Coosemans W, Depypere L, Van Veer H, Nafteux P
Ann Thorac Surg 2023 Sep;116(3):571-578. Epub 2023 Mar 30 doi: 10.1016/j.athoracsur.2023.02.060. PMID: 37003580
Kleinberg L, Brock M, Gibson M
Curr Treat Options Oncol 2015 Jul;16(7):35. doi: 10.1007/s11864-015-0352-6. PMID: 26112428Free PMC Article
Matuschek C, Bölke E, Peiper M, Knoefel WT, Budach W, Erhardt A, Scherer A, Gerber PA, Buhren BA, Gattermann N, Baldus SE, Rusnak E, Shukla V, Orth K
Eur J Med Res 2011 Jun 21;16(6):265-74. doi: 10.1186/2047-783x-16-6-265. PMID: 21810561Free PMC Article

Recent clinical studies

Etiology

Reynolds JV, Preston SR, O'Neill B, Lowery MA, Baeksgaard L, Crosby T, Cunningham M, Cuffe S, Griffiths GO, Parker I, Risumlund SL, Roy R, Falk S, Hanna GB, Bartlett FR, Alvarez-Iglesias A, Achiam MP, Nilsson M, Piessen G, Ravi N, O'Toole D, Johnston C, McDermott RS, Turkington RC, Wahed S, Sothi S, Ford H, Wadley MS, Power D; Neo-AEGIS Investigators and Trial Group
Lancet Gastroenterol Hepatol 2023 Nov;8(11):1015-1027. Epub 2023 Sep 18 doi: 10.1016/S2468-1253(23)00243-1. PMID: 37734399Free PMC Article
Benziane-Ouaritini N, Zilli T, Giraud A, Ingrosso G, Di Staso M, Trippa F, Pommier P, Meyer E, Francolini G, Schick U, Pasquier D, Marc Cosset J, Magne N, Martin E, Gnep K, Renard-Penna R, Anger E, Achard V, Giraud N, Aristei C, Ferrari V, Pasquier C, Zaine H, Osman O, Detti B, Perennec T, Mihoci I, Supiot S, Latorzeff I, Sargos P
Eur Urol Oncol 2023 Aug;6(4):390-398. Epub 2023 Apr 13 doi: 10.1016/j.euo.2023.02.013. PMID: 37059627
Vos EL, Carr RA, Hsu M, Nakauchi M, Nobel T, Russo A, Barbetta A, Tan KS, Tang L, Ilson D, Ku GY, Wu AJ, Janjigian YY, Yoon SS, Bains MS, Jones DR, Coit D, Molena D, Strong VE
Br J Surg 2021 Nov 11;108(11):1332-1340. doi: 10.1093/bjs/znab228. PMID: 34476473Free PMC Article
Salami AC, Obaid T, Nweze NJ, Deleon M, Force L, Gorgun E, Wexner S, Joshi ART
Colorectal Dis 2020 May;22(5):513-520. Epub 2019 Dec 20 doi: 10.1111/codi.14918. PMID: 31782601
Kauppi JT, Oksala N, Salo JA, Helin H, Karhumäki L, Kemppainen J, Sihvo EI, Räsänen JV
Acta Oncol 2012 May;51(5):636-44. Epub 2012 Jan 2 doi: 10.3109/0284186X.2011.643822. PMID: 22208782

Diagnosis

Vos EL, Carr RA, Hsu M, Nakauchi M, Nobel T, Russo A, Barbetta A, Tan KS, Tang L, Ilson D, Ku GY, Wu AJ, Janjigian YY, Yoon SS, Bains MS, Jones DR, Coit D, Molena D, Strong VE
Br J Surg 2021 Nov 11;108(11):1332-1340. doi: 10.1093/bjs/znab228. PMID: 34476473Free PMC Article
Werner J, Combs SE, Springfeld C, Hartwig W, Hackert T, Büchler MW
Nat Rev Clin Oncol 2013 Jun;10(6):323-33. Epub 2013 Apr 30 doi: 10.1038/nrclinonc.2013.66. PMID: 23629472
Kauppi JT, Oksala N, Salo JA, Helin H, Karhumäki L, Kemppainen J, Sihvo EI, Räsänen JV
Acta Oncol 2012 May;51(5):636-44. Epub 2012 Jan 2 doi: 10.3109/0284186X.2011.643822. PMID: 22208782
Cardenes HR, Chiorean EG, Dewitt J, Schmidt M, Loehrer P
Oncologist 2006 Jun;11(6):612-23. doi: 10.1634/theoncologist.11-6-612. PMID: 16794240
Evans DB
J Gastrointest Surg 2001 Jan-Feb;5(1):2-5. doi: 10.1016/s1091-255x(01)80002-0. PMID: 11370617

Therapy

Reynolds JV, Preston SR, O'Neill B, Lowery MA, Baeksgaard L, Crosby T, Cunningham M, Cuffe S, Griffiths GO, Parker I, Risumlund SL, Roy R, Falk S, Hanna GB, Bartlett FR, Alvarez-Iglesias A, Achiam MP, Nilsson M, Piessen G, Ravi N, O'Toole D, Johnston C, McDermott RS, Turkington RC, Wahed S, Sothi S, Ford H, Wadley MS, Power D; Neo-AEGIS Investigators and Trial Group
Lancet Gastroenterol Hepatol 2023 Nov;8(11):1015-1027. Epub 2023 Sep 18 doi: 10.1016/S2468-1253(23)00243-1. PMID: 37734399Free PMC Article
Tang Z, Wang Y, Liu D, Wang X, Xu C, Yu Y, Cui Y, Tang C, Li Q, Sun J, Zhang Q, Ji Y, Ma G, Li H, Shen Z, Shen K, Zheng R, Hou Z, Liu T, Wang J, Sun Y
Nat Commun 2022 Nov 10;13(1):6807. doi: 10.1038/s41467-022-34403-5. PMID: 36357415Free PMC Article
Kleinberg L, Brock M, Gibson M
Curr Treat Options Oncol 2015 Jul;16(7):35. doi: 10.1007/s11864-015-0352-6. PMID: 26112428Free PMC Article
Kleinberg L
Semin Radiat Oncol 2013 Jan;23(1):38-50. doi: 10.1016/j.semradonc.2012.10.001. PMID: 23207046
Lawton CA
Semin Radiat Oncol 2003 Apr;13(2):141-51. doi: 10.1053/srao.2003.50013. PMID: 12728443

Prognosis

Meillat H, Niziers V, Zemmour C, Ewald J, Ratone JP, Dermeche S, Guiramand J
World J Surg Oncol 2022 Mar 6;20(1):70. doi: 10.1186/s12957-022-02537-x. PMID: 35249555Free PMC Article
Vos EL, Carr RA, Hsu M, Nakauchi M, Nobel T, Russo A, Barbetta A, Tan KS, Tang L, Ilson D, Ku GY, Wu AJ, Janjigian YY, Yoon SS, Bains MS, Jones DR, Coit D, Molena D, Strong VE
Br J Surg 2021 Nov 11;108(11):1332-1340. doi: 10.1093/bjs/znab228. PMID: 34476473Free PMC Article
Kleinberg L, Brock M, Gibson M
Curr Treat Options Oncol 2015 Jul;16(7):35. doi: 10.1007/s11864-015-0352-6. PMID: 26112428Free PMC Article
Werner J, Combs SE, Springfeld C, Hartwig W, Hackert T, Büchler MW
Nat Rev Clin Oncol 2013 Jun;10(6):323-33. Epub 2013 Apr 30 doi: 10.1038/nrclinonc.2013.66. PMID: 23629472
Kauppi JT, Oksala N, Salo JA, Helin H, Karhumäki L, Kemppainen J, Sihvo EI, Räsänen JV
Acta Oncol 2012 May;51(5):636-44. Epub 2012 Jan 2 doi: 10.3109/0284186X.2011.643822. PMID: 22208782

Clinical prediction guides

Benziane-Ouaritini N, Zilli T, Giraud A, Ingrosso G, Di Staso M, Trippa F, Pommier P, Meyer E, Francolini G, Schick U, Pasquier D, Marc Cosset J, Magne N, Martin E, Gnep K, Renard-Penna R, Anger E, Achard V, Giraud N, Aristei C, Ferrari V, Pasquier C, Zaine H, Osman O, Detti B, Perennec T, Mihoci I, Supiot S, Latorzeff I, Sargos P
Eur Urol Oncol 2023 Aug;6(4):390-398. Epub 2023 Apr 13 doi: 10.1016/j.euo.2023.02.013. PMID: 37059627
Salami AC, Obaid T, Nweze NJ, Deleon M, Force L, Gorgun E, Wexner S, Joshi ART
Colorectal Dis 2020 May;22(5):513-520. Epub 2019 Dec 20 doi: 10.1111/codi.14918. PMID: 31782601
Werner J, Combs SE, Springfeld C, Hartwig W, Hackert T, Büchler MW
Nat Rev Clin Oncol 2013 Jun;10(6):323-33. Epub 2013 Apr 30 doi: 10.1038/nrclinonc.2013.66. PMID: 23629472
Kauppi JT, Oksala N, Salo JA, Helin H, Karhumäki L, Kemppainen J, Sihvo EI, Räsänen JV
Acta Oncol 2012 May;51(5):636-44. Epub 2012 Jan 2 doi: 10.3109/0284186X.2011.643822. PMID: 22208782
Lawton CA
Semin Radiat Oncol 2003 Apr;13(2):141-51. doi: 10.1053/srao.2003.50013. PMID: 12728443

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