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Advanced Pancreatobiliary Carcinoma

MedGen UID:
1720751
Concept ID:
C5419086
Neoplastic Process

Definition

A carcinoma that arises from the pancreas, bile ducts, gallbladder, or ampulla of Vater and has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Professional guidelines

PubMed

Kim BH, Yu SJ, Kang W, Cho SB, Park SY, Kim SU, Kim DY
J Gastroenterol Hepatol 2022 Mar;37(3):428-439. Epub 2021 Nov 17 doi: 10.1111/jgh.15727. PMID: 34725855Free PMC Article
Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
Cho CM
Korean J Gastroenterol 2019 Mar 25;73(3):124-131. doi: 10.4166/kjg.2019.73.3.124. PMID: 31013555

Recent clinical studies

Etiology

Nießen A, Loos M, Neumüller K, Feißt M, Klaiber U, Cizmic A, Al-Saeedi M, Roth S, Schneider M, Büchler MW, Hackert T
BJS Open 2023 Nov 1;7(6) doi: 10.1093/bjsopen/zrad120. PMID: 38155394Free PMC Article
Hur MH, Cho Y, Kim DY, Lee JS, Kim GM, Kim HC, Sinn DH, Hyun D, Lee HA, Seo YS, Lee IJ, Park JW, Kim YJ
Clin Mol Hepatol 2023 Jul;29(3):763-778. Epub 2023 May 30 doi: 10.3350/cmh.2023.0076. PMID: 37254488Free PMC Article
Shin DW, Kim S, Jung K, Jung JH, Kim B, Ahn J, Kim J, Hwang JH, Lee JC
Eur J Surg Oncol 2023 Feb;49(2):306-315. Epub 2022 Oct 9 doi: 10.1016/j.ejso.2022.10.001. PMID: 36272870
Yau T, Park JW, Finn RS, Cheng AL, Mathurin P, Edeline J, Kudo M, Harding JJ, Merle P, Rosmorduc O, Wyrwicz L, Schott E, Choo SP, Kelley RK, Sieghart W, Assenat E, Zaucha R, Furuse J, Abou-Alfa GK, El-Khoueiry AB, Melero I, Begic D, Chen G, Neely J, Wisniewski T, Tschaika M, Sangro B
Lancet Oncol 2022 Jan;23(1):77-90. Epub 2021 Dec 13 doi: 10.1016/S1470-2045(21)00604-5. PMID: 34914889
Parsi MA
World J Gastroenterol 2013 Jan 28;19(4):457-62. doi: 10.3748/wjg.v19.i4.457. PMID: 23382624Free PMC Article

Diagnosis

Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
He X, Zhu Y, Wang Y, Hao Y, Hong J
Abdom Radiol (NY) 2021 Jan;46(1):351-361. doi: 10.1007/s00261-020-02593-5. PMID: 32451676
Yamamoto K, Iwasaki E, Itoi T
Expert Rev Gastroenterol Hepatol 2020 Jun;14(6):435-444. Epub 2020 May 22 doi: 10.1080/17474124.2020.1766965. PMID: 32380873
Cho CM
Korean J Gastroenterol 2019 Mar 25;73(3):124-131. doi: 10.4166/kjg.2019.73.3.124. PMID: 31013555
Parsi MA
World J Gastroenterol 2013 Jan 28;19(4):457-62. doi: 10.3748/wjg.v19.i4.457. PMID: 23382624Free PMC Article

Therapy

Lee SU, Kim TH
Clin Mol Hepatol 2023 Oct;29(4):958-968. Epub 2023 Aug 29 doi: 10.3350/cmh.2023.0274. PMID: 37822213Free PMC Article
Yau T, Park JW, Finn RS, Cheng AL, Mathurin P, Edeline J, Kudo M, Harding JJ, Merle P, Rosmorduc O, Wyrwicz L, Schott E, Choo SP, Kelley RK, Sieghart W, Assenat E, Zaucha R, Furuse J, Abou-Alfa GK, El-Khoueiry AB, Melero I, Begic D, Chen G, Neely J, Wisniewski T, Tschaika M, Sangro B
Lancet Oncol 2022 Jan;23(1):77-90. Epub 2021 Dec 13 doi: 10.1016/S1470-2045(21)00604-5. PMID: 34914889
Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
Yamamoto K, Iwasaki E, Itoi T
Expert Rev Gastroenterol Hepatol 2020 Jun;14(6):435-444. Epub 2020 May 22 doi: 10.1080/17474124.2020.1766965. PMID: 32380873
Cho CM
Korean J Gastroenterol 2019 Mar 25;73(3):124-131. doi: 10.4166/kjg.2019.73.3.124. PMID: 31013555

Prognosis

Kim S, Leem G, Choi J, Koh Y, Lee S, Nam SH, Kim JS, Park CH, Hwang HK, Min KI, Jo JH, Lee HS, Chung MJ, Park JY, Park SW, Song SY, Shin EC, Kang CM, Bang S, Park JE
Genome Med 2024 Jan 31;16(1):20. doi: 10.1186/s13073-024-01287-7. PMID: 38297291Free PMC Article
Shin DW, Kim S, Jung K, Jung JH, Kim B, Ahn J, Kim J, Hwang JH, Lee JC
Eur J Surg Oncol 2023 Feb;49(2):306-315. Epub 2022 Oct 9 doi: 10.1016/j.ejso.2022.10.001. PMID: 36272870
Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
Cho CM
Korean J Gastroenterol 2019 Mar 25;73(3):124-131. doi: 10.4166/kjg.2019.73.3.124. PMID: 31013555
Parsi MA
World J Gastroenterol 2013 Jan 28;19(4):457-62. doi: 10.3748/wjg.v19.i4.457. PMID: 23382624Free PMC Article

Clinical prediction guides

Shin DW, Kim S, Jung K, Jung JH, Kim B, Ahn J, Kim J, Hwang JH, Lee JC
Eur J Surg Oncol 2023 Feb;49(2):306-315. Epub 2022 Oct 9 doi: 10.1016/j.ejso.2022.10.001. PMID: 36272870
Yau T, Park JW, Finn RS, Cheng AL, Mathurin P, Edeline J, Kudo M, Harding JJ, Merle P, Rosmorduc O, Wyrwicz L, Schott E, Choo SP, Kelley RK, Sieghart W, Assenat E, Zaucha R, Furuse J, Abou-Alfa GK, El-Khoueiry AB, Melero I, Begic D, Chen G, Neely J, Wisniewski T, Tschaika M, Sangro B
Lancet Oncol 2022 Jan;23(1):77-90. Epub 2021 Dec 13 doi: 10.1016/S1470-2045(21)00604-5. PMID: 34914889
Cho CM
Korean J Gastroenterol 2019 Mar 25;73(3):124-131. doi: 10.4166/kjg.2019.73.3.124. PMID: 31013555
Inui K, Yoshino J, Miyoshi H
Intern Med 2011;50(11):1133-6. Epub 2011 Jun 1 doi: 10.2169/internalmedicine.50.5255. PMID: 21628925
Yonezawa S, Higashi M, Yamada N, Yokoyama S, Goto M
J Hepatobiliary Pancreat Sci 2010 Mar;17(2):108-24. Epub 2009 Sep 29 doi: 10.1007/s00534-009-0174-7. PMID: 19787286

Recent systematic reviews

Shin DW, Kim S, Jung K, Jung JH, Kim B, Ahn J, Kim J, Hwang JH, Lee JC
Eur J Surg Oncol 2023 Feb;49(2):306-315. Epub 2022 Oct 9 doi: 10.1016/j.ejso.2022.10.001. PMID: 36272870
Bonet M, Rodrigo A, Vázquez S, Carrizo V, Vilardell F, Mira M
Clin Transl Oncol 2020 Aug;22(8):1407-1413. Epub 2020 Jan 11 doi: 10.1007/s12094-019-02278-6. PMID: 31927720

Supplemental Content

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