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Advanced Kidney Carcinoma

MedGen UID:
1742252
Concept ID:
C5419741
Neoplastic Process

Definition

Kidney carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Professional guidelines

PubMed

Wallis CJD, Novara G, Marandino L, Bex A, Kamat AM, Karnes RJ, Morgan TM, Mottet N, Gillessen S, Bossi A, Roupret M, Powles T, Necchi A, Catto JWF, Klaassen Z
Eur Urol 2020 Jul;78(1):29-42. Epub 2020 May 3 doi: 10.1016/j.eururo.2020.04.063. PMID: 32414626Free PMC Article

Recent clinical studies

Etiology

Chen YW, Wang L, Panian J, Dhanji S, Derweesh I, Rose B, Bagrodia A, McKay RR
Curr Treat Options Oncol 2023 Dec;24(12):1889-1916. Epub 2023 Dec 28 doi: 10.1007/s11864-023-01161-5. PMID: 38153686Free PMC Article
Bukavina L, Bensalah K, Bray F, Carlo M, Challacombe B, Karam JA, Kassouf W, Mitchell T, Montironi R, O'Brien T, Panebianco V, Scelo G, Shuch B, van Poppel H, Blosser CD, Psutka SP
Eur Urol 2022 Nov;82(5):529-542. Epub 2022 Sep 10 doi: 10.1016/j.eururo.2022.08.019. PMID: 36100483
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Motzer RJ, Jonasch E, Agarwal N, Alva A, Baine M, Beckermann K, Carlo MI, Choueiri TK, Costello BA, Derweesh IH, Desai A, Ged Y, George S, Gore JL, Haas N, Hancock SL, Kapur P, Kyriakopoulos C, Lam ET, Lara PN, Lau C, Lewis B, Madoff DC, Manley B, Michaelson MD, Mortazavi A, Nandagopal L, Plimack ER, Ponsky L, Ramalingam S, Shuch B, Smith ZL, Sosman J, Dwyer MA, Gurski LA, Motter A
J Natl Compr Canc Netw 2022 Jan;20(1):71-90. doi: 10.6004/jnccn.2022.0001. PMID: 34991070Free PMC Article
Iheanacho K, Vaishampayan U
Clin Adv Hematol Oncol 2020 Jan;18(1):56-65. PMID: 32511222

Diagnosis

Chen YW, Wang L, Panian J, Dhanji S, Derweesh I, Rose B, Bagrodia A, McKay RR
Curr Treat Options Oncol 2023 Dec;24(12):1889-1916. Epub 2023 Dec 28 doi: 10.1007/s11864-023-01161-5. PMID: 38153686Free PMC Article
Rosellini M, Marchetti A, Mollica V, Rizzo A, Santoni M, Massari F
Nat Rev Urol 2023 Mar;20(3):133-157. Epub 2022 Nov 21 doi: 10.1038/s41585-022-00676-0. PMID: 36414800
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Motzer RJ, Jonasch E, Agarwal N, Alva A, Baine M, Beckermann K, Carlo MI, Choueiri TK, Costello BA, Derweesh IH, Desai A, Ged Y, George S, Gore JL, Haas N, Hancock SL, Kapur P, Kyriakopoulos C, Lam ET, Lara PN, Lau C, Lewis B, Madoff DC, Manley B, Michaelson MD, Mortazavi A, Nandagopal L, Plimack ER, Ponsky L, Ramalingam S, Shuch B, Smith ZL, Sosman J, Dwyer MA, Gurski LA, Motter A
J Natl Compr Canc Netw 2022 Jan;20(1):71-90. doi: 10.6004/jnccn.2022.0001. PMID: 34991070Free PMC Article
Makhov P, Joshi S, Ghatalia P, Kutikov A, Uzzo RG, Kolenko VM
Mol Cancer Ther 2018 Jul;17(7):1355-1364. doi: 10.1158/1535-7163.MCT-17-1299. PMID: 29967214Free PMC Article

Therapy

Motzer RJ, Schmidinger M, Eto M, Suarez C, Figlin R, Liu Y, Perini R, Zhang Y, Heng DY
Future Oncol 2023 Jan;19(2):113-121. Epub 2023 Feb 8 doi: 10.2217/fon-2022-0802. PMID: 36752726
Makhov P, Joshi S, Ghatalia P, Kutikov A, Uzzo RG, Kolenko VM
Mol Cancer Ther 2018 Jul;17(7):1355-1364. doi: 10.1158/1535-7163.MCT-17-1299. PMID: 29967214Free PMC Article
Barata PC, Rini BI
CA Cancer J Clin 2017 Nov;67(6):507-524. Epub 2017 Sep 29 doi: 10.3322/caac.21411. PMID: 28961310
Jonasch E, Gao J, Rathmell WK
BMJ 2014 Nov 10;349:g4797. doi: 10.1136/bmj.g4797. PMID: 25385470Free PMC Article
Bukowski RM, Yasothan U, Kirkpatrick P
Nat Rev Drug Discov 2010 Jan;9(1):17-8. doi: 10.1038/nrd3073. PMID: 20043026

Prognosis

Chen YW, Wang L, Panian J, Dhanji S, Derweesh I, Rose B, Bagrodia A, McKay RR
Curr Treat Options Oncol 2023 Dec;24(12):1889-1916. Epub 2023 Dec 28 doi: 10.1007/s11864-023-01161-5. PMID: 38153686Free PMC Article
Rosellini M, Marchetti A, Mollica V, Rizzo A, Santoni M, Massari F
Nat Rev Urol 2023 Mar;20(3):133-157. Epub 2022 Nov 21 doi: 10.1038/s41585-022-00676-0. PMID: 36414800
Motzer RJ, Powles T, Burotto M, Escudier B, Bourlon MT, Shah AY, Suárez C, Hamzaj A, Porta C, Hocking CM, Kessler ER, Gurney H, Tomita Y, Bedke J, Zhang J, Simsek B, Scheffold C, Apolo AB, Choueiri TK
Lancet Oncol 2022 Jul;23(7):888-898. Epub 2022 Jun 7 doi: 10.1016/S1470-2045(22)00290-X. PMID: 35688173Free PMC Article
Jonasch E, Gao J, Rathmell WK
BMJ 2014 Nov 10;349:g4797. doi: 10.1136/bmj.g4797. PMID: 25385470Free PMC Article
Rini BI, Campbell SC, Escudier B
Lancet 2009 Mar 28;373(9669):1119-32. Epub 2009 Mar 5 doi: 10.1016/S0140-6736(09)60229-4. PMID: 19269025

Clinical prediction guides

Chen YW, Wang L, Panian J, Dhanji S, Derweesh I, Rose B, Bagrodia A, McKay RR
Curr Treat Options Oncol 2023 Dec;24(12):1889-1916. Epub 2023 Dec 28 doi: 10.1007/s11864-023-01161-5. PMID: 38153686Free PMC Article
Rosellini M, Marchetti A, Mollica V, Rizzo A, Santoni M, Massari F
Nat Rev Urol 2023 Mar;20(3):133-157. Epub 2022 Nov 21 doi: 10.1038/s41585-022-00676-0. PMID: 36414800
Bukavina L, Bensalah K, Bray F, Carlo M, Challacombe B, Karam JA, Kassouf W, Mitchell T, Montironi R, O'Brien T, Panebianco V, Scelo G, Shuch B, van Poppel H, Blosser CD, Psutka SP
Eur Urol 2022 Nov;82(5):529-542. Epub 2022 Sep 10 doi: 10.1016/j.eururo.2022.08.019. PMID: 36100483
Graham J, Heng DYC, Brugarolas J, Vaishampayan U
Am Soc Clin Oncol Educ Book 2018 May 23;38:330-341. doi: 10.1200/EDBK_201215. PMID: 30231375Free PMC Article
Amin A, Burgess EF
Semin Oncol 2016 Jun;43(3):408-12. Epub 2016 Feb 23 doi: 10.1053/j.seminoncol.2016.02.016. PMID: 27178696

Recent systematic reviews

Siva S, Louie AV, Kotecha R, Barber MN, Ali M, Zhang Z, Guckenberger M, Kim MS, Scorsetti M, Tree AC, Slotman BJ, Sahgal A, Lo SS
Lancet Oncol 2024 Jan;25(1):e18-e28. doi: 10.1016/S1470-2045(23)00513-2. PMID: 38181809
Aldin A, Besiroglu B, Adams A, Monsef I, Piechotta V, Tomlinson E, Hornbach C, Dressen N, Goldkuhle M, Maisch P, Dahm P, Heidenreich A, Skoetz N
Cochrane Database Syst Rev 2023 May 4;5(5):CD013798. doi: 10.1002/14651858.CD013798.pub2. PMID: 37146227Free PMC Article
Cozma A, Sporis ND, Lazar AL, Buruiana A, Ganea AM, Malinescu TV, Berechet BM, Fodor A, Sitar-Taut AV, Vlad VC, Negrean V, Orasan OH
Int J Mol Sci 2022 Sep 19;23(18) doi: 10.3390/ijms231810948. PMID: 36142866Free PMC Article
Bukavina L, Bensalah K, Bray F, Carlo M, Challacombe B, Karam JA, Kassouf W, Mitchell T, Montironi R, O'Brien T, Panebianco V, Scelo G, Shuch B, van Poppel H, Blosser CD, Psutka SP
Eur Urol 2022 Nov;82(5):529-542. Epub 2022 Sep 10 doi: 10.1016/j.eururo.2022.08.019. PMID: 36100483
Wu Z, Chen Q, Qu L, Li M, Wang L, Mir MC, Carbonara U, Pandolfo SD, Black PC, Paul AK, Di Lorenzo G, Porpiglia F, Mari A, Necchi A, Rouprêt M, Psutka SP, Autorino R
Eur Urol 2022 Apr;81(4):414-425. Epub 2022 Jan 31 doi: 10.1016/j.eururo.2022.01.028. PMID: 35101302

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