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Benign Head and Neck Neoplasm

MedGen UID:
1747379
Concept ID:
C5420464
Neoplastic Process

Definition

A neoplasm that arises from the head and neck and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Head and Neck Neoplasm

Professional guidelines

PubMed

Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Alexander EK, Doherty GM, Barletta JA
Lancet Diabetes Endocrinol 2022 Jul;10(7):540-548. doi: 10.1016/S2213-8587(22)00139-5. PMID: 35752201
Grani G, Sponziello M, Pecce V, Ramundo V, Durante C
J Clin Endocrinol Metab 2020 Sep 1;105(9):2869-83. doi: 10.1210/clinem/dgaa322. PMID: 32491169Free PMC Article

Recent clinical studies

Etiology

Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN
Int Forum Allergy Rhinol 2024 Feb;14(2):149-608. Epub 2024 Jan 2 doi: 10.1002/alr.23262. PMID: 37658764
Sandow L, Thawani R, Kim MS, Heinrich MC
Endocr Pract 2023 Feb;29(2):141-147. Epub 2022 Oct 15 doi: 10.1016/j.eprac.2022.10.002. PMID: 36252779Free PMC Article
Tufano RP, Pace-Asciak P, Russell JO, Suárez C, Randolph GW, López F, Shaha AR, Mäkitie A, Rodrigo JP, Kowalski LP, Zafereo M, Angelos P, Ferlito A
Front Endocrinol (Lausanne) 2021;12:698689. Epub 2021 Jun 24 doi: 10.3389/fendo.2021.698689. PMID: 34248853Free PMC Article
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Mendenhall WM, Amdur RJ, Vaysberg M, Mendenhall CM, Werning JW
Head Neck 2011 Oct;33(10):1530-4. Epub 2010 Nov 4 doi: 10.1002/hed.21524. PMID: 21928426

Diagnosis

Ettinger KS, Yetzer JG
Oral Maxillofac Surg Clin North Am 2017 Nov;29(4):487-501. doi: 10.1016/j.coms.2017.07.004. PMID: 28987229
Schwarz Y, Pitaro J, Waissbluth S, Daniel SJ
Int J Pediatr Otorhinolaryngol 2016 Jun;85:148-53. Epub 2016 Mar 28 doi: 10.1016/j.ijporl.2016.03.026. PMID: 27240514
Capatina C, Ntali G, Karavitaki N, Grossman AB
Endocr Relat Cancer 2013 Oct;20(5):R291-305. Epub 2013 Aug 23 doi: 10.1530/ERC-13-0223. PMID: 23921204
Prisco MK
Nurse Pract 2000 Apr;25(4):30-2, 35-6, 38 passim; quiz 50-1. doi: 10.1097/00006205-200025040-00002. PMID: 10790797
Batsakis JG, Raymond AK
Ann Otol Rhinol Laryngol 1994 Jan;103(1):77-9. doi: 10.1177/000348949410300115. PMID: 8291864

Therapy

Qiao G, Zhuang W, Dong B, Li C, Xu J, Wang G, Xie L, Zhou Z, Tian D, Chen G, Tang J, Zhou H, Zhang D, Shi R, Chen R, Nian W, Zhang Y, Zhao J, Wen X, Xu Y, Li B, Zhang Z, Cai S, Ben X, Qi Y
BMC Med 2021 Oct 13;19(1):243. doi: 10.1186/s12916-021-02109-y. PMID: 34641873Free PMC Article
Muhammad H, Santhanam P, Russell JO
Endocrine 2021 Jun;72(3):619-632. Epub 2021 Jan 15 doi: 10.1007/s12020-020-02598-6. PMID: 33449296
Livhits MJ, Zhu CY, Kuo EJ, Nguyen DT, Kim J, Tseng CH, Leung AM, Rao J, Levin M, Douek ML, Beckett KR, Cheung DS, Gofnung YA, Smooke-Praw S, Yeh MW
JAMA Oncol 2021 Jan 1;7(1):70-77. doi: 10.1001/jamaoncol.2020.5935. PMID: 33300952Free PMC Article
Johnston J, Allen JE
Curr Opin Otolaryngol Head Neck Surg 2018 Dec;26(6):403-408. doi: 10.1097/MOO.0000000000000487. PMID: 30234659
Reiter R, Hoffmann TK, Pickhard A, Brosch S
Dtsch Arztebl Int 2015 May 8;112(19):329-37. doi: 10.3238/arztebl.2015.0329. PMID: 26043420Free PMC Article

Prognosis

Müller M, Li J, Giger R, Elicin O
Oral Oncol 2023 Oct;145:106529. Epub 2023 Jul 26 doi: 10.1016/j.oraloncology.2023.106529. PMID: 37506514
Feygin T, Khalek N, Moldenhauer JS
Prenat Diagn 2020 Sep;40(10):1203-1219. Epub 2020 May 26 doi: 10.1002/pd.5722. PMID: 32350893
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406
Batsakis JG, Raymond AK
Ann Otol Rhinol Laryngol 1994 Jan;103(1):77-9. doi: 10.1177/000348949410300115. PMID: 8291864
Bale PM, Painter DM, Cohen D
Pathology 1975 Jul;7(3):209-18. doi: 10.3109/00313027509094411. PMID: 1196679

Clinical prediction guides

Müller M, Li J, Giger R, Elicin O
Oral Oncol 2023 Oct;145:106529. Epub 2023 Jul 26 doi: 10.1016/j.oraloncology.2023.106529. PMID: 37506514
Sandow L, Thawani R, Kim MS, Heinrich MC
Endocr Pract 2023 Feb;29(2):141-147. Epub 2022 Oct 15 doi: 10.1016/j.eprac.2022.10.002. PMID: 36252779Free PMC Article
Zhao CX, Dombrowski ND, Perez-Atayde AR, Robson CD, Afshar S, Janeway KA, Rahbar R
Int J Pediatr Otorhinolaryngol 2021 Jan;140:110511. Epub 2020 Nov 18 doi: 10.1016/j.ijporl.2020.110511. PMID: 33271436
Steward DL, Carty SE, Sippel RS, Yang SP, Sosa JA, Sipos JA, Figge JJ, Mandel S, Haugen BR, Burman KD, Baloch ZW, Lloyd RV, Seethala RR, Gooding WE, Chiosea SI, Gomes-Lima C, Ferris RL, Folek JM, Khawaja RA, Kundra P, Loh KS, Marshall CB, Mayson S, McCoy KL, Nga ME, Ngiam KY, Nikiforova MN, Poehls JL, Ringel MD, Yang H, Yip L, Nikiforov YE
JAMA Oncol 2019 Feb 1;5(2):204-212. doi: 10.1001/jamaoncol.2018.4616. PMID: 30419129Free PMC Article
Prisco MK
Nurse Pract 2000 Apr;25(4):30-2, 35-6, 38 passim; quiz 50-1. doi: 10.1097/00006205-200025040-00002. PMID: 10790797

Recent systematic reviews

Zeyghami W, Hansen MU, Jakobsen KK, Groenhøj C, Feldt-Rasmussen U, von Buchwald C, Hahn CH
Endocr Relat Cancer 2023 Dec 1;30(12) Epub 2023 Oct 26 doi: 10.1530/ERC-23-0002. PMID: 37882489
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Muhammad H, Santhanam P, Russell JO
Endocrine 2021 Jun;72(3):619-632. Epub 2021 Jan 15 doi: 10.1007/s12020-020-02598-6. PMID: 33449296
Schwarz Y, Pitaro J, Waissbluth S, Daniel SJ
Int J Pediatr Otorhinolaryngol 2016 Jun;85:148-53. Epub 2016 Mar 28 doi: 10.1016/j.ijporl.2016.03.026. PMID: 27240514
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893

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