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Intrarenal reflux

MedGen UID:
1778612
•Concept ID:
C5539787
•
Disease or Syndrome
HPO: HP:0033742

Definition

Severe vesicoureteral reflux reaching the kidney parenchyma. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntrarenal reflux

Professional guidelines

PubMed

Flexible ureteroscopic lithotripsy for the treatment of upper urinary tract calculi in infants.
Li J, Xiao J, Han T, Tian Y, Wang W, Du Y
Exp Biol Med (Maywood) 2017 Jan;242(2):153-159. Epub 2016 Oct 4 doi: 10.1177/1535370216669836. PMID: 27633576Free PMC Article
Renal aneurysm and arteriovenous fistula. Management with transcatheter embolization.
Savastano S, Feltrin GP, Miotto D, Chiesura-Corona M
Acta Radiol 1990 Jan;31(1):73-6. PMID: 2340225

Recent clinical studies

Etiology

Pathogenesis and prognosis of intrarenal reflux.
Gkalonaki I, Schoina E, Anastasakis M, Patoulias I
Folia Med Cracov 2023 Jul 30;63(2):57-64. doi: 10.24425/fmc.2023.145913. PMID: 37903379
Prevalence of intrarenal reflux in pediatric patients on contrast-enhanced voiding urosonography.
Klein EL, Wyers MR, Prendergast FM, Arzu J, Benya EC
Pediatr Radiol 2023 Mar;53(3):387-393. Epub 2022 Nov 29 doi: 10.1007/s00247-022-05548-8. PMID: 36447052
Intrarenal reflux in primary vesicoureteral reflux.
Fukui S, Watanabe M, Yoshino K
Int J Urol 2013 Jun;20(6):631-6. Epub 2012 Nov 27 doi: 10.1111/iju.12015. PMID: 23186044
Vesicoureteric reflux and renal injury.
Arant BS Jr
Am J Kidney Dis 1991 May;17(5):491-511. doi: 10.1016/s0272-6386(12)80490-2. PMID: 2024650
Intrarenal reflux.
Uldall P, Frøokjaer O, Kaas Ibsen K
Acta Paediatr Scand 1976 Nov;65(6):711-5. doi: 10.1111/j.1651-2227.1976.tb18008.x. PMID: 998230

Diagnosis

Pathogenesis and prognosis of intrarenal reflux.
Gkalonaki I, Schoina E, Anastasakis M, Patoulias I
Folia Med Cracov 2023 Jul 30;63(2):57-64. doi: 10.24425/fmc.2023.145913. PMID: 37903379
Contrast-enhanced voiding urosonography in the diagnosis of intrarenal reflux.
Cvitkovic-Roic A, Turudic D, Milosevic D, Palcic I, Roic G
J Ultrasound 2022 Mar;25(1):89-95. Epub 2021 Feb 26 doi: 10.1007/s40477-021-00568-w. PMID: 33635511Free PMC Article
Diagnosis of vesico-ureteric reflux.
Hellström M, Jacobsson B
Acta Paediatr Suppl 1999 Nov;88(431):3-12. doi: 10.1111/j.1651-2227.1999.tb01313.x. PMID: 10588266
Intrarenal reflux and nephropathy.
Shigematsu H, Murakami S
Nihon Jinzo Gakkai Shi 1990 Mar;32(3):331-7. PMID: 2192186
Vesicoureteral reflux and reflux nephropathy.
Thomsen HS
Acta Radiol Diagn (Stockh) 1985 Jan-Feb;26(1):3-13. doi: 10.1177/028418518502600102. PMID: 3883698

Therapy

Predicting factors of breakthrough infection in children with primary vesicoureteral reflux.
Jang HC, Park YJ, Park JS
Yonsei Med J 2012 Jul 1;53(4):748-52. doi: 10.3349/ymj.2012.53.4.748. PMID: 22665341Free PMC Article
Risk factors for recurrent urinary tract infection in preschool children.
Panaretto K, Craig J, Knight J, Howman-Giles R, Sureshkumar P, Roy L
J Paediatr Child Health 1999 Oct;35(5):454-9. doi: 10.1046/j.1440-1754.1999.355417.x. PMID: 10571758
Reflux nephropathy.
Becker GJ
Aust N Z J Med 1985 Oct;15(5):668-76. PMID: 3911933
Ureterosigmoidostomy: the development of tumors, diagnosis, and pitfalls.
Princenthal RA, Lowman R, Zeman RK, Burrell M
AJR Am J Roentgenol 1983 Jul;141(1):77-81. doi: 10.2214/ajr.141.1.77. PMID: 6602534
The possibility of scar formation due to intrarenal reflux in analgesic nephropathy.
Laberke HG
Virchows Arch A Pathol Anat Histol 1981;394(1-2):161-6. doi: 10.1007/BF00431674. PMID: 7336572

Prognosis

Pathogenesis and prognosis of intrarenal reflux.
Gkalonaki I, Schoina E, Anastasakis M, Patoulias I
Folia Med Cracov 2023 Jul 30;63(2):57-64. doi: 10.24425/fmc.2023.145913. PMID: 37903379
Evolution and prognosis value of intrarenal reflux.
Boubnova J, Sergent-Alaoui A, Deschênes G, Audry G
J Pediatr Urol 2011 Dec;7(6):638-43. Epub 2010 Oct 14 doi: 10.1016/j.jpurol.2010.09.015. PMID: 20951095
Do kidneys outgrow the risk of reflux nephropathy?
Coulthard MG
Pediatr Nephrol 2002 Jul;17(7):477-80. Epub 2002 Jun 7 doi: 10.1007/s00467-002-0877-3. PMID: 12172757
Intrarenal reflux.
Uldall P, Frøokjaer O, Kaas Ibsen K
Acta Paediatr Scand 1976 Nov;65(6):711-5. doi: 10.1111/j.1651-2227.1976.tb18008.x. PMID: 998230
Intrarenal reflux and the scarred kidney.
Rolleston GL, Maling TM, Hodson CJ
Arch Dis Child 1974 Jul;49(7):531-9. doi: 10.1136/adc.49.7.531. PMID: 4852544Free PMC Article

Clinical prediction guides

Intrarenal reflux in primary vesicoureteral reflux.
Fukui S, Watanabe M, Yoshino K
Int J Urol 2013 Jun;20(6):631-6. Epub 2012 Nov 27 doi: 10.1111/iju.12015. PMID: 23186044
Evolution and prognosis value of intrarenal reflux.
Boubnova J, Sergent-Alaoui A, Deschênes G, Audry G
J Pediatr Urol 2011 Dec;7(6):638-43. Epub 2010 Oct 14 doi: 10.1016/j.jpurol.2010.09.015. PMID: 20951095
Vesicoureteric reflux and renal injury.
Arant BS Jr
Am J Kidney Dis 1991 May;17(5):491-511. doi: 10.1016/s0272-6386(12)80490-2. PMID: 2024650
Intrarenal reflux and nephropathy.
Shigematsu H, Murakami S
Nihon Jinzo Gakkai Shi 1990 Mar;32(3):331-7. PMID: 2192186
Intrarenal reflux and the scarred kidney.
Rolleston GL, Maling TM, Hodson CJ
Arch Dis Child 1974 Jul;49(7):531-9. doi: 10.1136/adc.49.7.531. PMID: 4852544Free PMC Article

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