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Advanced Triple-Negative Breast Carcinoma

MedGen UID:
1784796
Concept ID:
C5446362
Neoplastic Process

Definition

Triple-negative breast carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Triple-Negative Breast Carcinoma

Professional guidelines

PubMed

Bianchini G, De Angelis C, Licata L, Gianni L
Nat Rev Clin Oncol 2022 Feb;19(2):91-113. Epub 2021 Nov 9 doi: 10.1038/s41571-021-00565-2. PMID: 34754128
Jiang YZ, Ma D, Suo C, Shi J, Xue M, Hu X, Xiao Y, Yu KD, Liu YR, Yu Y, Zheng Y, Li X, Zhang C, Hu P, Zhang J, Hua Q, Zhang J, Hou W, Ren L, Bao D, Li B, Yang J, Yao L, Zuo WJ, Zhao S, Gong Y, Ren YX, Zhao YX, Yang YS, Niu Z, Cao ZG, Stover DG, Verschraegen C, Kaklamani V, Daemen A, Benson JR, Takabe K, Bai F, Li DQ, Wang P, Shi L, Huang W, Shao ZM
Cancer Cell 2019 Mar 18;35(3):428-440.e5. Epub 2019 Mar 7 doi: 10.1016/j.ccell.2019.02.001. PMID: 30853353
Garrido-Castro AC, Lin NU, Polyak K
Cancer Discov 2019 Feb;9(2):176-198. Epub 2019 Jan 24 doi: 10.1158/2159-8290.CD-18-1177. PMID: 30679171Free PMC Article

Recent clinical studies

Etiology

Karim AM, Eun Kwon J, Ali T, Jang J, Ullah I, Lee YG, Park DW, Park J, Jeang JW, Kang SC
Biochem Pharmacol 2023 Jun;212:115545. Epub 2023 Apr 11 doi: 10.1016/j.bcp.2023.115545. PMID: 37044296
Bianchini G, De Angelis C, Licata L, Gianni L
Nat Rev Clin Oncol 2022 Feb;19(2):91-113. Epub 2021 Nov 9 doi: 10.1038/s41571-021-00565-2. PMID: 34754128
Garrido-Castro AC, Lin NU, Polyak K
Cancer Discov 2019 Feb;9(2):176-198. Epub 2019 Jan 24 doi: 10.1158/2159-8290.CD-18-1177. PMID: 30679171Free PMC Article
Masuda N, Lee SJ, Ohtani S, Im YH, Lee ES, Yokota I, Kuroi K, Im SA, Park BW, Kim SB, Yanagita Y, Ohno S, Takao S, Aogi K, Iwata H, Jeong J, Kim A, Park KH, Sasano H, Ohashi Y, Toi M
N Engl J Med 2017 Jun 1;376(22):2147-2159. doi: 10.1056/NEJMoa1612645. PMID: 28564564
Kumar P, Aggarwal R
Arch Gynecol Obstet 2016 Feb;293(2):247-69. Epub 2015 Sep 4 doi: 10.1007/s00404-015-3859-y. PMID: 26341644

Diagnosis

Leon-Ferre RA, Goetz MP
BMJ 2023 May 30;381:e071674. doi: 10.1136/bmj-2022-071674. PMID: 37253507
Li Y, Zhang H, Merkher Y, Chen L, Liu N, Leonov S, Chen Y
J Hematol Oncol 2022 Aug 29;15(1):121. doi: 10.1186/s13045-022-01341-0. PMID: 36038913Free PMC Article
Keenan TE, Tolaney SM
J Natl Compr Canc Netw 2020 Apr;18(4):479-489. doi: 10.6004/jnccn.2020.7554. PMID: 32259782
Garrido-Castro AC, Lin NU, Polyak K
Cancer Discov 2019 Feb;9(2):176-198. Epub 2019 Jan 24 doi: 10.1158/2159-8290.CD-18-1177. PMID: 30679171Free PMC Article
Kumar P, Aggarwal R
Arch Gynecol Obstet 2016 Feb;293(2):247-69. Epub 2015 Sep 4 doi: 10.1007/s00404-015-3859-y. PMID: 26341644

Therapy

Keenan TE, Tolaney SM
J Natl Compr Canc Netw 2020 Apr;18(4):479-489. doi: 10.6004/jnccn.2020.7554. PMID: 32259782
Lyons TG
Curr Treat Options Oncol 2019 Nov 21;20(11):82. doi: 10.1007/s11864-019-0682-x. PMID: 31754897
Schmid P, Adams S, Rugo HS, Schneeweiss A, Barrios CH, Iwata H, Diéras V, Hegg R, Im SA, Shaw Wright G, Henschel V, Molinero L, Chui SY, Funke R, Husain A, Winer EP, Loi S, Emens LA; IMpassion130 Trial Investigators
N Engl J Med 2018 Nov 29;379(22):2108-2121. Epub 2018 Oct 20 doi: 10.1056/NEJMoa1809615. PMID: 30345906
Masuda N, Lee SJ, Ohtani S, Im YH, Lee ES, Yokota I, Kuroi K, Im SA, Park BW, Kim SB, Yanagita Y, Ohno S, Takao S, Aogi K, Iwata H, Jeong J, Kim A, Park KH, Sasano H, Ohashi Y, Toi M
N Engl J Med 2017 Jun 1;376(22):2147-2159. doi: 10.1056/NEJMoa1612645. PMID: 28564564
Bianchini G, Balko JM, Mayer IA, Sanders ME, Gianni L
Nat Rev Clin Oncol 2016 Nov;13(11):674-690. Epub 2016 May 17 doi: 10.1038/nrclinonc.2016.66. PMID: 27184417Free PMC Article

Prognosis

Roy M, Fowler AM, Ulaner GA, Mahajan A
PET Clin 2023 Oct;18(4):441-458. Epub 2023 May 31 doi: 10.1016/j.cpet.2023.04.002. PMID: 37268505
Li Y, Zhang H, Merkher Y, Chen L, Liu N, Leonov S, Chen Y
J Hematol Oncol 2022 Aug 29;15(1):121. doi: 10.1186/s13045-022-01341-0. PMID: 36038913Free PMC Article
Garrido-Castro AC, Lin NU, Polyak K
Cancer Discov 2019 Feb;9(2):176-198. Epub 2019 Jan 24 doi: 10.1158/2159-8290.CD-18-1177. PMID: 30679171Free PMC Article
Masuda N, Lee SJ, Ohtani S, Im YH, Lee ES, Yokota I, Kuroi K, Im SA, Park BW, Kim SB, Yanagita Y, Ohno S, Takao S, Aogi K, Iwata H, Jeong J, Kim A, Park KH, Sasano H, Ohashi Y, Toi M
N Engl J Med 2017 Jun 1;376(22):2147-2159. doi: 10.1056/NEJMoa1612645. PMID: 28564564
Kumar P, Aggarwal R
Arch Gynecol Obstet 2016 Feb;293(2):247-69. Epub 2015 Sep 4 doi: 10.1007/s00404-015-3859-y. PMID: 26341644

Clinical prediction guides

Roy M, Fowler AM, Ulaner GA, Mahajan A
PET Clin 2023 Oct;18(4):441-458. Epub 2023 May 31 doi: 10.1016/j.cpet.2023.04.002. PMID: 37268505
Agostinetto E, Losurdo A, Nader-Marta G, Santoro A, Punie K, Barroso R, Popovic L, Solinas C, Kok M, de Azambuja E, Lambertini M
Expert Opin Investig Drugs 2022 Jun;31(6):567-591. Epub 2022 Mar 9 doi: 10.1080/13543784.2022.2049232. PMID: 35240902
Najjar S, Allison KH
Virchows Arch 2022 Jan;480(1):163-176. Epub 2022 Jan 14 doi: 10.1007/s00428-022-03267-x. PMID: 35029776
Al-Mahmood S, Sapiezynski J, Garbuzenko OB, Minko T
Drug Deliv Transl Res 2018 Oct;8(5):1483-1507. doi: 10.1007/s13346-018-0551-3. PMID: 29978332Free PMC Article
Kumar P, Aggarwal R
Arch Gynecol Obstet 2016 Feb;293(2):247-69. Epub 2015 Sep 4 doi: 10.1007/s00404-015-3859-y. PMID: 26341644

Recent systematic reviews

Schettini F, Venturini S, Giuliano M, Lambertini M, Pinato DJ, Onesti CE, De Placido P, Harbeck N, Lüftner D, Denys H, Van Dam P, Arpino G, Zaman K, Mustacchi G, Gligorov J, Awada A, Campone M, Wildiers H, Gennari A, Tjan-Heijnen V, Bartsch R, Cortes J, Paris I, Martín M, De Placido S, Del Mastro L, Jerusalem G, Curigliano G, Prat A, Generali D
Cancer Treat Rev 2022 Dec;111:102468. Epub 2022 Sep 28 doi: 10.1016/j.ctrv.2022.102468. PMID: 36202026
Zhang M, Song J, Yang H, Jin F, Zheng A
Acta Oncol 2022 Sep;61(9):1105-1115. Epub 2022 Aug 8 doi: 10.1080/0284186X.2022.2106795. PMID: 35939538
Ali MA, Aiman W, Shah SS, Hussain M, Kashyap R
Crit Rev Oncol Hematol 2021 Jan;157:103197. Epub 2020 Dec 10 doi: 10.1016/j.critrevonc.2020.103197. PMID: 33309890
Diana A, Franzese E, Centonze S, Carlino F, Della Corte CM, Ventriglia J, Petrillo A, De Vita F, Alfano R, Ciardiello F, Orditura M
Curr Oncol Rep 2018 Aug 20;20(10):76. doi: 10.1007/s11912-018-0726-6. PMID: 30128845
Gelmon K, Dent R, Mackey JR, Laing K, McLeod D, Verma S
Ann Oncol 2012 Sep;23(9):2223-2234. Epub 2012 Apr 19 doi: 10.1093/annonc/mds067. PMID: 22517820

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