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Advanced Rectal Adenocarcinoma

MedGen UID:
1784958
Concept ID:
C5446470
Neoplastic Process

Definition

Rectal adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Rectal Adenocarcinoma

Professional guidelines

PubMed

Felder SI, Fleming JB, Gatenby RA
Adv Cancer Res 2021;151:39-67. Epub 2021 Apr 9 doi: 10.1016/bs.acr.2021.02.003. PMID: 34148619
Lukovic J, Kim JJ, Krzyzanowska M, Chadi SA, Taniguchi CM, Hosni A
JCO Oncol Pract 2020 Oct;16(10):635-640. doi: 10.1200/OP.20.00363. PMID: 33049179
Akce M, El-Rayes BF
J Oncol Pract 2019 Mar;15(3):123-131. doi: 10.1200/JOP.18.00769. PMID: 30861368

Recent clinical studies

Etiology

Diefenhardt M, Martin D, Fleischmann M, Hofheinz RD, Ghadimi M, Rödel C, Fokas E
JAMA Netw Open 2023 Oct 2;6(10):e2340256. doi: 10.1001/jamanetworkopen.2023.40256. PMID: 37902752Free PMC Article
Yamazaki T, Gunderson AJ, Gilchrist M, Whiteford M, Kiely MX, Hayman A, O'Brien D, Ahmad R, Manchio JV, Fox N, McCarty K, Phillips M, Brosnan E, Vaccaro G, Li R, Simon M, Bernstein E, McCormick M, Yamasaki L, Wu Y, Drokin A, Carnahan T, To Y, Redmond WL, Lee B, Louie J, Hansen E, Solhjem MC, Cramer J, Urba WJ, Gough MJ, Crittenden MR, Young KH
Lancet Oncol 2022 Sep;23(9):1189-1200. Epub 2022 Aug 8 doi: 10.1016/S1470-2045(22)00446-6. PMID: 35952709
Desouza A, Kazi M, Bankar S, Pandey D, Janesh M, Saklani A
ANZ J Surg 2022 Oct;92(10):2595-2599. Epub 2022 Jun 28 doi: 10.1111/ans.17888. PMID: 35762325
Leung G, Nishimura M, Hingorani N, Lin IH, Weiser MR, Garcia-Aguilar J, Pappou EP, Paty PB, Schattner MA
Gastrointest Endosc 2022 Aug;96(2):359-367. Epub 2022 Feb 17 doi: 10.1016/j.gie.2022.02.014. PMID: 35183541
Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Kranenbarg EM, Roodvoets AGH, Nagtegaal ID, Beets-Tan RGH, Blomqvist LK, Fokstuen T, Ten Tije AJ, Capdevila J, Hendriks MP, Edhemovic I, Cervantes A, Nilsson PJ, Glimelius B, van de Velde CJH, Hospers GAP; RAPIDO collaborative investigators
Lancet Oncol 2021 Jan;22(1):29-42. Epub 2020 Dec 7 doi: 10.1016/S1470-2045(20)30555-6. PMID: 33301740

Diagnosis

Leung G, Nishimura M, Hingorani N, Lin IH, Weiser MR, Garcia-Aguilar J, Pappou EP, Paty PB, Schattner MA
Gastrointest Endosc 2022 Aug;96(2):359-367. Epub 2022 Feb 17 doi: 10.1016/j.gie.2022.02.014. PMID: 35183541
Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Kranenbarg EM, Roodvoets AGH, Nagtegaal ID, Beets-Tan RGH, Blomqvist LK, Fokstuen T, Ten Tije AJ, Capdevila J, Hendriks MP, Edhemovic I, Cervantes A, Nilsson PJ, Glimelius B, van de Velde CJH, Hospers GAP; RAPIDO collaborative investigators
Lancet Oncol 2021 Jan;22(1):29-42. Epub 2020 Dec 7 doi: 10.1016/S1470-2045(20)30555-6. PMID: 33301740
Akce M, El-Rayes BF
J Oncol Pract 2019 Mar;15(3):123-131. doi: 10.1200/JOP.18.00769. PMID: 30861368
Pokharkar A, Kammar P, D'souza A, Bhamre R, Sugoor P, Saklani A
J Laparoendosc Adv Surg Tech A 2018 Dec;28(12):1489-1494. Epub 2018 May 9 doi: 10.1089/lap.2018.0147. PMID: 29741977
Conde-Muíño R, Cuadros M, Zambudio N, Segura-Jiménez I, Cano C, Palma P
Biomed Res Int 2015;2015:921435. Epub 2015 Oct 4 doi: 10.1155/2015/921435. PMID: 26504848Free PMC Article

Therapy

Mehta R, Frakes J, Kim J, Nixon A, Liu Y, Howard L, Martinez Jimenez ME, Carballido E, Imanirad I, Sanchez J, Dessureault S, Xie H, Felder S, Sahin I, Hoffe S, Malafa M, Kim R
Oncologist 2022 Aug 5;27(8):621-e617. doi: 10.1093/oncolo/oyac003. PMID: 35325225Free PMC Article
De Felice F, D'Ambrosio G, Iafrate F, Gelibter A, Magliocca FM, Musio D, Caponetto S, Casella G, Clementi I, Picchetto A, Sirgiovani G, Parisi M, Orciuoli C, Torrese G, De Toma G, Tombolini V, Cortesi E
Clin Oncol (R Coll Radiol) 2021 Dec;33(12):788-794. Epub 2021 Jun 24 doi: 10.1016/j.clon.2021.06.006. PMID: 34176711
Felder SI, Fleming JB, Gatenby RA
Adv Cancer Res 2021;151:39-67. Epub 2021 Apr 9 doi: 10.1016/bs.acr.2021.02.003. PMID: 34148619
Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Kranenbarg EM, Roodvoets AGH, Nagtegaal ID, Beets-Tan RGH, Blomqvist LK, Fokstuen T, Ten Tije AJ, Capdevila J, Hendriks MP, Edhemovic I, Cervantes A, Nilsson PJ, Glimelius B, van de Velde CJH, Hospers GAP; RAPIDO collaborative investigators
Lancet Oncol 2021 Jan;22(1):29-42. Epub 2020 Dec 7 doi: 10.1016/S1470-2045(20)30555-6. PMID: 33301740
Akce M, El-Rayes BF
J Oncol Pract 2019 Mar;15(3):123-131. doi: 10.1200/JOP.18.00769. PMID: 30861368

Prognosis

Felder SI, Fleming JB, Gatenby RA
Adv Cancer Res 2021;151:39-67. Epub 2021 Apr 9 doi: 10.1016/bs.acr.2021.02.003. PMID: 34148619
Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Kranenbarg EM, Roodvoets AGH, Nagtegaal ID, Beets-Tan RGH, Blomqvist LK, Fokstuen T, Ten Tije AJ, Capdevila J, Hendriks MP, Edhemovic I, Cervantes A, Nilsson PJ, Glimelius B, van de Velde CJH, Hospers GAP; RAPIDO collaborative investigators
Lancet Oncol 2021 Jan;22(1):29-42. Epub 2020 Dec 7 doi: 10.1016/S1470-2045(20)30555-6. PMID: 33301740
Akce M, El-Rayes BF
J Oncol Pract 2019 Mar;15(3):123-131. doi: 10.1200/JOP.18.00769. PMID: 30861368
Pettit C, Walston S, Wald P, Webb A, Williams TM
Int J Oncol 2017 Aug;51(2):393-404. Epub 2017 Jun 14 doi: 10.3892/ijo.2017.4045. PMID: 28627602
Conde-Muíño R, Cuadros M, Zambudio N, Segura-Jiménez I, Cano C, Palma P
Biomed Res Int 2015;2015:921435. Epub 2015 Oct 4 doi: 10.1155/2015/921435. PMID: 26504848Free PMC Article

Clinical prediction guides

Felder SI, Fleming JB, Gatenby RA
Adv Cancer Res 2021;151:39-67. Epub 2021 Apr 9 doi: 10.1016/bs.acr.2021.02.003. PMID: 34148619
Bahadoer RR, Dijkstra EA, van Etten B, Marijnen CAM, Putter H, Kranenbarg EM, Roodvoets AGH, Nagtegaal ID, Beets-Tan RGH, Blomqvist LK, Fokstuen T, Ten Tije AJ, Capdevila J, Hendriks MP, Edhemovic I, Cervantes A, Nilsson PJ, Glimelius B, van de Velde CJH, Hospers GAP; RAPIDO collaborative investigators
Lancet Oncol 2021 Jan;22(1):29-42. Epub 2020 Dec 7 doi: 10.1016/S1470-2045(20)30555-6. PMID: 33301740
Pai RK, Pai RK
Mod Pathol 2018 Jan;31(1):4-23. Epub 2017 Aug 4 doi: 10.1038/modpathol.2017.87. PMID: 28776577
Pettit C, Walston S, Wald P, Webb A, Williams TM
Int J Oncol 2017 Aug;51(2):393-404. Epub 2017 Jun 14 doi: 10.3892/ijo.2017.4045. PMID: 28627602
Conde-Muíño R, Cuadros M, Zambudio N, Segura-Jiménez I, Cano C, Palma P
Biomed Res Int 2015;2015:921435. Epub 2015 Oct 4 doi: 10.1155/2015/921435. PMID: 26504848Free PMC Article

Recent systematic reviews

Petrelli F, Trevisan F, Tomasello G, De Stefani A, Viti M, Garrone O, Luciani A, Ghidini M
Crit Rev Oncol Hematol 2022 Dec;180:103853. Epub 2022 Oct 15 doi: 10.1016/j.critrevonc.2022.103853. PMID: 36252747
Rymer B, Curtis NJ, Siddiqui MR, Chand M
Clin Nucl Med 2016 May;41(5):371-5. doi: 10.1097/RLU.0000000000001166. PMID: 26914561

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