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Psychosomatic factor in physical condition

MedGen UID:
18744
•Concept ID:
C0033931
•
Mental or Behavioral Dysfunction
Synonyms: Psychophysiologic Disorder; Psychophysiologic Disorders; Psychophysiological Disorder; Psychophysiological Disorders; Psychosomatic Disorder; Psychosomatic Disorders
SNOMED CT: Psychosomatic factor in physical condition (26112003); Psychological factor affecting physical condition (26112003); Psychophysiologic disorder (26112003)

Definition

A group of disorders characterized by physical symptoms that are affected by emotional factors and involve a single organ system, usually under AUTONOMIC NERVOUS SYSTEM control. (American Psychiatric Glossary, 1988) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPsychosomatic factor in physical condition

Professional guidelines

PubMed

Treatment of Psychogenic Nonepileptic Seizures.
Lopez MR, LaFrance WC
Curr Neurol Neurosci Rep 2022 Aug;22(8):467-474. Epub 2022 Jun 8 doi: 10.1007/s11910-022-01209-3. PMID: 35674871
Management of functional neurological disorder.
Gilmour GS, Nielsen G, Teodoro T, Yogarajah M, Coebergh JA, Dilley MD, Martino D, Edwards MJ
J Neurol 2020 Jul;267(7):2164-2172. Epub 2020 Mar 19 doi: 10.1007/s00415-020-09772-w. PMID: 32193596Free PMC Article
Management of psychogenic non-epileptic seizures: a multidisciplinary approach.
Gasparini S, Beghi E, Ferlazzo E, Beghi M, Belcastro V, Biermann KP, Bottini G, Capovilla G, Cervellione RA, Cianci V, Coppola G, Cornaggia CM, De Fazio P, De Masi S, De Sarro G, Elia M, Erba G, Fusco L, Gambardella A, Gentile V, Giallonardo AT, Guerrini R, Ingravallo F, Iudice A, Labate A, Lucenteforte E, Magaudda A, Mumoli L, Papagno C, Pesce GB, Pucci E, Ricci P, Romeo A, Quintas R, Sueri C, Vitaliti G, Zoia R, Aguglia U
Eur J Neurol 2019 Feb;26(2):205-e15. Epub 2018 Nov 29 doi: 10.1111/ene.13818. PMID: 30300463

Recent clinical studies

Etiology

Evaluation and Treatment of Psychogenic Nonepileptic Seizures.
Beimer NJ, LaFrance WC Jr
Neurol Clin 2022 Nov;40(4):799-820. Epub 2022 Sep 28 doi: 10.1016/j.ncl.2022.03.017. PMID: 36270692
The aetiology of psychogenic non-epileptic seizures: risk factors and comorbidities.
Popkirov S, Asadi-Pooya AA, Duncan R, Gigineishvili D, Hingray C, Miguel Kanner A, LaFrance WC Jr, Pretorius C, Reuber M
Epileptic Disord 2019 Dec 1;21(6):529-547. doi: 10.1684/epd.2019.1107. PMID: 31843732
Management of psychogenic non-epileptic seizures: a multidisciplinary approach.
Gasparini S, Beghi E, Ferlazzo E, Beghi M, Belcastro V, Biermann KP, Bottini G, Capovilla G, Cervellione RA, Cianci V, Coppola G, Cornaggia CM, De Fazio P, De Masi S, De Sarro G, Elia M, Erba G, Fusco L, Gambardella A, Gentile V, Giallonardo AT, Guerrini R, Ingravallo F, Iudice A, Labate A, Lucenteforte E, Magaudda A, Mumoli L, Papagno C, Pesce GB, Pucci E, Ricci P, Romeo A, Quintas R, Sueri C, Vitaliti G, Zoia R, Aguglia U
Eur J Neurol 2019 Feb;26(2):205-e15. Epub 2018 Nov 29 doi: 10.1111/ene.13818. PMID: 30300463
Psychogenic nonepileptic seizures.
Lortie A
Handb Clin Neurol 2013;112:875-9. doi: 10.1016/B978-0-444-52910-7.00009-X. PMID: 23622297
Risk-management syndrome.
Tanaka M, Watanabe Y
Int J Psychiatry Clin Pract 2012 Oct;16(4):312-5. Epub 2012 Feb 17 doi: 10.3109/13651501.2011.653378. PMID: 22339176

Diagnosis

Management of functional neurological disorder.
Gilmour GS, Nielsen G, Teodoro T, Yogarajah M, Coebergh JA, Dilley MD, Martino D, Edwards MJ
J Neurol 2020 Jul;267(7):2164-2172. Epub 2020 Mar 19 doi: 10.1007/s00415-020-09772-w. PMID: 32193596Free PMC Article
The aetiology of psychogenic non-epileptic seizures: risk factors and comorbidities.
Popkirov S, Asadi-Pooya AA, Duncan R, Gigineishvili D, Hingray C, Miguel Kanner A, LaFrance WC Jr, Pretorius C, Reuber M
Epileptic Disord 2019 Dec 1;21(6):529-547. doi: 10.1684/epd.2019.1107. PMID: 31843732
Psychogenic itch.
Misery L, Dutray S, Chastaing M, Schollhammer M, Consoli SG, Consoli SM
Transl Psychiatry 2018 Mar 1;8(1):52. doi: 10.1038/s41398-018-0097-7. PMID: 29491364Free PMC Article
Current Psychosomatic Practice.
Fava GA, Cosci F, Sonino N
Psychother Psychosom 2017;86(1):13-30. Epub 2016 Nov 25 doi: 10.1159/000448856. PMID: 27884006
Psychogenic non-epileptic seizures.
Doss RC, LaFrance WC Jr
Epileptic Disord 2016 Dec 1;18(4):337-343. doi: 10.1684/epd.2016.0873. PMID: 27818368

Therapy

Physical treatment of functional neurologic disorders.
Nielsen G
Handb Clin Neurol 2016;139:555-569. doi: 10.1016/B978-0-12-801772-2.00045-X. PMID: 27719871
Psychogenic Itch Management.
Szepietowski JC, Reszke R
Curr Probl Dermatol 2016;50:124-32. Epub 2016 Aug 23 doi: 10.1159/000446055. PMID: 27578081
Commentary: psychodermatology.
Gupta MA
Clin Dermatol 2013 Jan-Feb;31(1):1-2. doi: 10.1016/j.clindermatol.2011.11.018. PMID: 23245967
Psychogenic movement disorders.
Gupta A, Lang AE
Curr Opin Neurol 2009 Aug;22(4):430-6. doi: 10.1097/WCO.0b013e32832dc169. PMID: 19542886
Psychogenic nonepileptic seizures.
Alsaadi TM, Marquez AV
Am Fam Physician 2005 Sep 1;72(5):849-56. PMID: 16156345

Prognosis

Current Psychosomatic Practice.
Fava GA, Cosci F, Sonino N
Psychother Psychosom 2017;86(1):13-30. Epub 2016 Nov 25 doi: 10.1159/000448856. PMID: 27884006
Psychogenic nonepileptic seizures.
Lortie A
Handb Clin Neurol 2013;112:875-9. doi: 10.1016/B978-0-444-52910-7.00009-X. PMID: 23622297
Psychogenic movement disorders.
Gupta A, Lang AE
Curr Opin Neurol 2009 Aug;22(4):430-6. doi: 10.1097/WCO.0b013e32832dc169. PMID: 19542886
Psychogenic gait disorders.
Sudarsky L
Semin Neurol 2006 Jul;26(3):351-6. doi: 10.1055/s-2006-945523. PMID: 16791781
Psychosomatic backache.
Sarno JE
J Fam Pract 1977 Sep;5(3):353-7. PMID: 143507

Clinical prediction guides

Psychological inflexibility and somatization in nonepileptic attack disorder.
Cullingham T, Kirkby A, Eccles FJR, Sellwood W
Epilepsy Behav 2020 Oct;111:107155. Epub 2020 Jun 17 doi: 10.1016/j.yebeh.2020.107155. PMID: 32563053
Psychoneuroimmunology: The Experiential Dimension.
Ulvestad E
Methods Mol Biol 2018;1781:37-53. doi: 10.1007/978-1-4939-7828-1_3. PMID: 29705841
Mood and anxiety in the medically ill.
Bech P
Adv Psychosom Med 2012;32:118-132. Epub 2011 Oct 19 doi: 10.1159/000330012. PMID: 22056902
Psychogenic gait disorders.
Sudarsky L
Semin Neurol 2006 Jul;26(3):351-6. doi: 10.1055/s-2006-945523. PMID: 16791781
Physical disease and schizophrenia.
Harris AE
Schizophr Bull 1988;14(1):85-96. doi: 10.1093/schbul/14.1.85. PMID: 3291096

Recent systematic reviews

Psychopathology Associated with Chronic Pruritus: A Systematic Review.
Ferreira BR, Misery L
Acta Derm Venereol 2023 Aug 22;103:adv8488. doi: 10.2340/actadv.v103.8488. PMID: 37606153Free PMC Article
Clinical utility of demoralization: A systematic review of the literature.
Woźniewicz A, Cosci F
Clin Psychol Rev 2023 Feb;99:102227. Epub 2022 Nov 25 doi: 10.1016/j.cpr.2022.102227. PMID: 36462221
Treatments for Burning Mouth Syndrome: A Network Meta-analysis.
Alvarenga-Brant R, Costa FO, Mattos-Pereira G, Esteves-Lima RP, Belém FV, Lai H, Ge L, Gomez RS, Martins CC
J Dent Res 2023 Feb;102(2):135-145. Epub 2022 Oct 8 doi: 10.1177/00220345221130025. PMID: 36214096
The association of panic and hyperventilation with psychogenic non-epileptic seizures: A systematic review and meta-analysis.
Indranada AM, Mullen SA, Duncan R, Berlowitz DJ, Kanaan RAA
Seizure 2018 Jul;59:108-115. Epub 2018 May 19 doi: 10.1016/j.seizure.2018.05.007. PMID: 29787922
Biomarkers in the diagnosis and study of psychogenic nonepileptic seizures: A systematic review.
Sundararajan T, Tesar GE, Jimenez XF
Seizure 2016 Feb;35:11-22. Epub 2015 Dec 31 doi: 10.1016/j.seizure.2015.12.011. PMID: 26774202

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