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Thoracic aortic dissection

MedGen UID:
196449
Concept ID:
C0729233
Disease or Syndrome
Synonyms: Aorta Dissection, Thoracic; Aortic Dissection, Thoracic; Dissection, Thoracic Aorta; Dissection, Thoracic Aortic; Thoracic Aorta Dissection; Thoracic Aorta Dissections; Thoracic Aortic Dissection; Thoracic Aortic Dissections
SNOMED CT: Dissection of thoracic aorta (233994002)

Definition

Dissection or a tear of the THORACIC AORTA. It includes aortic root dissection, ascending aortic dissection, aortic arch dissection and descending thoracic aortic dissection. [from MeSH]

Professional guidelines

PubMed

Spanos K, Nana P, Behrendt CA, Kouvelos G, Panuccio G, Heidemann F, Matsagkas M, Debus ES, Giannoukas A, Kölbel T
J Endovasc Ther 2021 Apr;28(2):323-331. Epub 2021 Jan 13 doi: 10.1177/1526602820987808. PMID: 33435805
Mokashi SA, Svensson LG
Gen Thorac Cardiovasc Surg 2019 Jan;67(1):59-65. Epub 2017 Oct 13 doi: 10.1007/s11748-017-0831-8. PMID: 29030719
Lin PH, Huynh TT, Kougias P, Huh J, LeMaire SA, Coselli JS
Vasc Endovascular Surg 2009 Feb-Mar;43(1):5-24. Epub 2008 Jun 25 doi: 10.1177/1538574408318475. PMID: 18583304

Recent clinical studies

Etiology

Hameed I, Cifu AS, Vallabhajosyula P
JAMA 2023 Mar 7;329(9):756-757. doi: 10.1001/jama.2023.0265. PMID: 36795378
Rylski B, Schilling O, Czerny M
Eur Heart J 2023 Mar 7;44(10):813-821. doi: 10.1093/eurheartj/ehac757. PMID: 36540036
Zhou Z, Cecchi AC, Prakash SK, Milewicz DM
Genes (Basel) 2022 Oct 7;13(10) doi: 10.3390/genes13101814. PMID: 36292699Free PMC Article
Senser EM, Misra S, Henkin S
Cardiol Clin 2021 Nov;39(4):505-515. doi: 10.1016/j.ccl.2021.06.003. PMID: 34686263
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506

Diagnosis

Hameed I, Cifu AS, Vallabhajosyula P
JAMA 2023 Mar 7;329(9):756-757. doi: 10.1001/jama.2023.0265. PMID: 36795378
Rylski B, Schilling O, Czerny M
Eur Heart J 2023 Mar 7;44(10):813-821. doi: 10.1093/eurheartj/ehac757. PMID: 36540036
Senser EM, Misra S, Henkin S
Cardiol Clin 2021 Nov;39(4):505-515. doi: 10.1016/j.ccl.2021.06.003. PMID: 34686263
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506
Goldfinger JZ, Halperin JL, Marin ML, Stewart AS, Eagle KA, Fuster V
J Am Coll Cardiol 2014 Oct 21;64(16):1725-39. doi: 10.1016/j.jacc.2014.08.025. PMID: 25323262

Therapy

Yang M, Zhou X, Pearce SWA, Yang Z, Chen Q, Niu K, Liu C, Luo J, Li D, Shao Y, Zhang C, Chen D, Wu Q, Cutillas PR, Zhao L, Xiao Q, Zhang L
Arterioscler Thromb Vasc Biol 2023 Oct;43(10):1900-1920. Epub 2023 Aug 17 doi: 10.1161/ATVBAHA.123.319281. PMID: 37589142Free PMC Article
Meccanici F, Gökalp AL, Thijssen CGE, Mokhles MM, Bekkers JA, van Kimmenade R, Verhagen HJ, Roos-Hesselink JW, Takkenberg JJM
Interact Cardiovasc Thorac Surg 2022 Mar 31;34(4):616-627. doi: 10.1093/icvts/ivab270. PMID: 34664071Free PMC Article
Takagi H, Umemoto T
Int Angiol 2016 Oct;35(5):433-9. Epub 2015 Jul 29 PMID: 26221978
Subramanian S, Roselli EE
Semin Vasc Surg 2009 Jun;22(2):61-8. doi: 10.1053/j.semvascsurg.2009.04.006. PMID: 19573743
Zhang X, Shen YH, LeMaire SA
Vascular 2009 May-Jun;17(3):147-57. doi: 10.2310/6670.2008.00087. PMID: 19476747Free PMC Article

Prognosis

Senser EM, Misra S, Henkin S
Cardiol Clin 2021 Nov;39(4):505-515. doi: 10.1016/j.ccl.2021.06.003. PMID: 34686263
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506
Adriaans BP, Wildberger JE, Westenberg JJM, Lamb HJ, Schalla S
Eur Radiol 2019 Dec;29(12):6396-6404. Epub 2019 Jul 5 doi: 10.1007/s00330-019-06320-7. PMID: 31278573Free PMC Article
Shalhub S, Dua A, Brooks J
Semin Vasc Surg 2014 Dec;27(3-4):196-9. Epub 2015 Jan 16 doi: 10.1053/j.semvascsurg.2015.01.001. PMID: 26073830
Grubb KJ, Kron IL
Semin Thorac Cardiovasc Surg 2011 Summer;23(2):124-5. doi: 10.1053/j.semtcvs.2011.08.009. PMID: 22041041

Clinical prediction guides

Salmasi MY, Pirola S, Asimakopoulos G, Nienaber C, Athanasiou T; London Aortic Mechanobiology Working Group
J Thorac Cardiovasc Surg 2023 Oct;166(4):1034-1042. Epub 2022 May 16 doi: 10.1016/j.jtcvs.2022.05.016. PMID: 35672182
Luo BY, Zhou J, Guo D, Yang Q, Tian Q, Cai DP, Zhou RM, Xu ZZ, Wang HJ, Chen SY, Xie WB
Biochim Biophys Acta Mol Basis Dis 2022 Sep 1;1868(9):166447. Epub 2022 May 25 doi: 10.1016/j.bbadis.2022.166447. PMID: 35643386Free PMC Article
Senser EM, Misra S, Henkin S
Cardiol Clin 2021 Nov;39(4):505-515. doi: 10.1016/j.ccl.2021.06.003. PMID: 34686263
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506
Adriaans BP, Wildberger JE, Westenberg JJM, Lamb HJ, Schalla S
Eur Radiol 2019 Dec;29(12):6396-6404. Epub 2019 Jul 5 doi: 10.1007/s00330-019-06320-7. PMID: 31278573Free PMC Article

Recent systematic reviews

Rai P, Robinson L, Davies HA, Akhtar R, Field M, Madine J
Int J Mol Sci 2022 Aug 16;23(16) doi: 10.3390/ijms23169200. PMID: 36012466Free PMC Article
Li HL, Chan YC, Jia HY, Cheng SW
Ann Vasc Surg 2022 Sep;85:371-382. Epub 2022 Mar 24 doi: 10.1016/j.avsg.2022.03.020. PMID: 35339592
Meccanici F, Gökalp AL, Thijssen CGE, Mokhles MM, Bekkers JA, van Kimmenade R, Verhagen HJ, Roos-Hesselink JW, Takkenberg JJM
Interact Cardiovasc Thorac Surg 2022 Mar 31;34(4):616-627. doi: 10.1093/icvts/ivab270. PMID: 34664071Free PMC Article
Spanos K, Nana P, Behrendt CA, Kouvelos G, Panuccio G, Heidemann F, Matsagkas M, Debus ES, Giannoukas A, Kölbel T
J Endovasc Ther 2021 Apr;28(2):323-331. Epub 2021 Jan 13 doi: 10.1177/1526602820987808. PMID: 33435805
Li T, Lv Z, Jing JJ, Yang J, Yuan Y
Clin Genet 2018 Jan;93(1):15-32. Epub 2017 Jul 18 doi: 10.1111/cge.13050. PMID: 28485889

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