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Posterior cerebral artery infarction

MedGen UID:
199818
•Concept ID:
C0752132
•
Disease or Syndrome
Synonyms: Infarct, PCA; Infarction, PCA; Infarction, Posterior Cerebral Artery; Infarcts, PCA; PCA Infarct; PCA Infarction; PCA Infarcts; Posterior Cerebral Artery Infarction; Posterior Cerebral Artery Stroke; Stroke, Posterior Cerebral Artery
 
Monarch Initiative: MONDO:0006917

Definition

Necrosis induced by ischemia in the posterior cerebral artery distribution system which supplies portions of the brain stem; the thalamus; temporal lobe, and occipital lobe. Depending on the size and location of infarction, clinical features include olfaction disorders and visual problems (agnosia; alexia; hemianopsia). [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPosterior cerebral artery infarction

Professional guidelines

PubMed

T2/FLAIR Hyperintensity in Mesial Temporal Lobe: Challenging Differential Diagnosis.
Moon S
Curr Med Imaging 2022;18(3):285-291. doi: 10.2174/1573405617666210712130555. PMID: 34931987

Recent clinical studies

Etiology

Acute isolated posterior cerebral artery stroke treated with mechanical thrombectomy: A single-center experience and review of the literature.
Baig AA, Monteiro A, Waqas M, Cappuzzo JM, Siddiqi M, Doane J, Dossani RH, Almayman F, Khawar WI, Davies JM, Snyder KV, Levy EI, Siddiqui AH
Interv Neuroradiol 2023 Feb;29(1):10-19. Epub 2022 Jan 10 doi: 10.1177/15910199211070949. PMID: 35001703Free PMC Article
The amnestic syndrome of posterior cerebral artery infarction.
Benke T, Bodner T, Wiesen D, Karnath HO
Eur J Neurol 2022 Oct;29(10):2987-2995. Epub 2022 Jul 14 doi: 10.1111/ene.15449. PMID: 35708171Free PMC Article
Mechanical thrombectomy for acute posterior cerebral artery stroke; Feasibility and predictors of outcome.
Baik SH, Jung C, Kim BM, Kim DJ
Neuroradiology 2022 Jul;64(7):1419-1427. Epub 2022 Feb 8 doi: 10.1007/s00234-022-02910-3. PMID: 35133483
Lesion topography of posterior cerebral artery infarcts.
Benke T, Dazinger F, Pechlaner R, Willeit K, Clausen J, Knoflach M
J Neurol Sci 2021 Sep 15;428:117585. Epub 2021 Jul 24 doi: 10.1016/j.jns.2021.117585. PMID: 34371243
Posterior cerebral artery territory infarctions.
Cereda C, Carrera E
Front Neurol Neurosci 2012;30:128-31. Epub 2012 Feb 14 doi: 10.1159/000333610. PMID: 22377879

Diagnosis

Demographics, Risk Factors, and Etiology of Posterior Cerebral Artery Stroke Causing Homonymous Hemianopia.
Liu EA, Murali S, Rivera-de Choudens R, Trobe JD
J Neuroophthalmol 2023 Sep 1;43(3):387-392. Epub 2023 Jul 12 doi: 10.1097/WNO.0000000000001948. PMID: 37436886
Presenting Symptoms and Imaging Features of Posterior Cerebral Artery Stroke Causing Homonymous Hemianopia.
Liu EA, Murali S, Rivera-de Choudens R, Trobe JD
J Neuroophthalmol 2023 Sep 1;43(3):393-398. Epub 2023 Jul 12 doi: 10.1097/WNO.0000000000001934. PMID: 37436872
Acute isolated posterior cerebral artery stroke treated with mechanical thrombectomy: A single-center experience and review of the literature.
Baig AA, Monteiro A, Waqas M, Cappuzzo JM, Siddiqi M, Doane J, Dossani RH, Almayman F, Khawar WI, Davies JM, Snyder KV, Levy EI, Siddiqui AH
Interv Neuroradiol 2023 Feb;29(1):10-19. Epub 2022 Jan 10 doi: 10.1177/15910199211070949. PMID: 35001703Free PMC Article
Lateral Thalamic Infarction and the Vascular Geometry of the Posterior Cerebral Artery.
Kim BJ, Kim SM, Ahn SH, Kang DW, Kwon SU, Kim JS
Cerebrovasc Dis 2016;41(1-2):8-12. Epub 2015 Nov 19 doi: 10.1159/000439062. PMID: 26580422
Sonographic stroke templates.
Govaert P
Semin Fetal Neonatal Med 2009 Oct;14(5):284-98. Epub 2009 Aug 13 doi: 10.1016/j.siny.2009.07.006. PMID: 19682961

Therapy

Thrombectomy vs Medical Management for Posterior Cerebral Artery Stroke: Systematic Review, Meta-Analysis, and Real-World Data.
Chen H, Khunte M, Colasurdo M, Malhotra A, Gandhi D
Neurology 2024 May;102(9):e209315. Epub 2024 Apr 16 doi: 10.1212/WNL.0000000000209315. PMID: 38626383
Demographics, Risk Factors, and Etiology of Posterior Cerebral Artery Stroke Causing Homonymous Hemianopia.
Liu EA, Murali S, Rivera-de Choudens R, Trobe JD
J Neuroophthalmol 2023 Sep 1;43(3):387-392. Epub 2023 Jul 12 doi: 10.1097/WNO.0000000000001948. PMID: 37436886
Characteristics of dynamic cerebral autoregulation in cerebral small vessel disease: Diffuse and sustained.
Guo ZN, Xing Y, Wang S, Ma H, Liu J, Yang Y
Sci Rep 2015 Oct 15;5:15269. doi: 10.1038/srep15269. PMID: 26469343Free PMC Article
Intravenous thrombolysis in posterior cerebral artery infarctions.
Breuer L, Huttner HB, Jentsch K, Blinzler C, Winder K, Engelhorn T, Köhrmann M
Cerebrovasc Dis 2011;31(5):448-54. Epub 2011 Feb 24 doi: 10.1159/000323253. PMID: 21346350
Posterior cerebral artery infarction from middle cerebral artery infarction.
Maulaz AB, Bezerra DC, Bogousslavsky J
Arch Neurol 2005 Jun;62(6):938-41. doi: 10.1001/archneur.62.6.938. PMID: 15956164

Prognosis

Correlation of Macular Sparing and Homonymous Paracentral Scotomas With MRI Lesions in Posterior Cerebral Artery Infarction.
Cho J, Liao E, Trobe JD
J Neuroophthalmol 2022 Sep 1;42(3):367-371. Epub 2022 Jun 14 doi: 10.1097/WNO.0000000000001603. PMID: 36166761
Mechanical thrombectomy for acute posterior cerebral artery stroke; Feasibility and predictors of outcome.
Baik SH, Jung C, Kim BM, Kim DJ
Neuroradiology 2022 Jul;64(7):1419-1427. Epub 2022 Feb 8 doi: 10.1007/s00234-022-02910-3. PMID: 35133483
Differences in Ischemic Anterior and Posterior Circulation Strokes: A Clinico-Radiological and Outcome Analysis.
Zürcher E, Richoz B, Faouzi M, Michel P
J Stroke Cerebrovasc Dis 2019 Mar;28(3):710-718. Epub 2018 Nov 28 doi: 10.1016/j.jstrokecerebrovasdis.2018.11.016. PMID: 30501979
Etiology and Risk Factors of Posterior Circulation Infarction Compared with Anterior Circulation Infarction.
Zeng Q, Tao W, Lei C, Dong W, Liu M
J Stroke Cerebrovasc Dis 2015 Jul;24(7):1614-20. Epub 2015 Apr 17 doi: 10.1016/j.jstrokecerebrovasdis.2015.03.033. PMID: 25899158
Sonographic stroke templates.
Govaert P
Semin Fetal Neonatal Med 2009 Oct;14(5):284-98. Epub 2009 Aug 13 doi: 10.1016/j.siny.2009.07.006. PMID: 19682961

Clinical prediction guides

Acute isolated posterior cerebral artery stroke treated with mechanical thrombectomy: A single-center experience and review of the literature.
Baig AA, Monteiro A, Waqas M, Cappuzzo JM, Siddiqi M, Doane J, Dossani RH, Almayman F, Khawar WI, Davies JM, Snyder KV, Levy EI, Siddiqui AH
Interv Neuroradiol 2023 Feb;29(1):10-19. Epub 2022 Jan 10 doi: 10.1177/15910199211070949. PMID: 35001703Free PMC Article
The amnestic syndrome of posterior cerebral artery infarction.
Benke T, Bodner T, Wiesen D, Karnath HO
Eur J Neurol 2022 Oct;29(10):2987-2995. Epub 2022 Jul 14 doi: 10.1111/ene.15449. PMID: 35708171Free PMC Article
Mechanical thrombectomy for acute posterior cerebral artery stroke; Feasibility and predictors of outcome.
Baik SH, Jung C, Kim BM, Kim DJ
Neuroradiology 2022 Jul;64(7):1419-1427. Epub 2022 Feb 8 doi: 10.1007/s00234-022-02910-3. PMID: 35133483
T2/FLAIR Hyperintensity in Mesial Temporal Lobe: Challenging Differential Diagnosis.
Moon S
Curr Med Imaging 2022;18(3):285-291. doi: 10.2174/1573405617666210712130555. PMID: 34931987
Sonographic stroke templates.
Govaert P
Semin Fetal Neonatal Med 2009 Oct;14(5):284-98. Epub 2009 Aug 13 doi: 10.1016/j.siny.2009.07.006. PMID: 19682961

Recent systematic reviews

Thrombectomy vs Medical Management for Posterior Cerebral Artery Stroke: Systematic Review, Meta-Analysis, and Real-World Data.
Chen H, Khunte M, Colasurdo M, Malhotra A, Gandhi D
Neurology 2024 May;102(9):e209315. Epub 2024 Apr 16 doi: 10.1212/WNL.0000000000209315. PMID: 38626383
Acute isolated posterior cerebral artery stroke treated with mechanical thrombectomy: A single-center experience and review of the literature.
Baig AA, Monteiro A, Waqas M, Cappuzzo JM, Siddiqi M, Doane J, Dossani RH, Almayman F, Khawar WI, Davies JM, Snyder KV, Levy EI, Siddiqui AH
Interv Neuroradiol 2023 Feb;29(1):10-19. Epub 2022 Jan 10 doi: 10.1177/15910199211070949. PMID: 35001703Free PMC Article
Stroke risk after posterior circulation stroke/transient ischemic attack and its relationship to site of vertebrobasilar stenosis: pooled data analysis from prospective studies.
Gulli G, Marquardt L, Rothwell PM, Markus HS
Stroke 2013 Mar;44(3):598-604. Epub 2013 Feb 5 doi: 10.1161/STROKEAHA.112.669929. PMID: 23386676

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