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Stage IIIB Breast Inflammatory Carcinoma

MedGen UID:
208889
•Concept ID:
C0853971
•
Neoplastic Process
Synonyms: Stage IIIB Inflammatory Breast Cancer; Stage IIIB Inflammatory Breast Carcinoma

Definition

Inflammatory breast carcinoma is classified as AJCC Stage IIIB (T4d) unless other criteria indicate more advanced staging. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage IIIB Breast Inflammatory Carcinoma

Professional guidelines

PubMed

Management of locally advanced breast cancer. Mini-review.
Franceschini G, Terribile D, Fabbri C, Magno S, D'Alba P, Chiesa F, Di Leone A, Masetti R
Minerva Chir 2007 Aug;62(4):249-55. PMID: 17641585
Preoperative therapy in breast cancer: lessons from the treatment of locally advanced disease.
Wolff AC, Davidson NE
Oncologist 2002;7(3):239-45. doi: 10.1634/theoncologist.7-3-239. PMID: 12065797
Management of stage III breast cancer.
Honkoop AH, Wagstaff J, Pinedo HM
Oncology 1998 May-Jun;55(3):218-27. doi: 10.1159/000011861. PMID: 9560054

Recent clinical studies

Etiology

Senescent mesenchymal stem/stromal cells in pre-metastatic bone marrow of untreated advanced breast cancer patients.
Borzone FR, Giorello MB, Martinez LM, Sanmartin MC, Feldman L, Dimase F, Batagelj E, Yannarelli G, Chasseing NA
Oncol Res 2023;31(3):361-374. Epub 2023 May 24 doi: 10.32604/or.2023.028104. PMID: 37305388Free PMC Article
Locally advanced breast cancer.
Aebi S, Karlsson P, Wapnir IL
Breast 2022 Mar;62 Suppl 1(Suppl 1):S58-S62. Epub 2021 Dec 15 doi: 10.1016/j.breast.2021.12.011. PMID: 34930650Free PMC Article
Delayed breast reconstruction with tram-flap and various modifications after radical mastectomy.
Smolanka II, Bagmut IY, Sheremet MI, Lyashenko AO, Movchan OV, Smolanka II Jr, Loboda AD, Kolisnyk IL, Sydorchuk LP, Lazaruk OV
J Med Life 2021 Nov-Dec;14(6):847-852. doi: 10.25122/jml-2021-0354. PMID: 35126757Free PMC Article
Management of locally advanced breast cancer. Mini-review.
Franceschini G, Terribile D, Fabbri C, Magno S, D'Alba P, Chiesa F, Di Leone A, Masetti R
Minerva Chir 2007 Aug;62(4):249-55. PMID: 17641585
Scope and significance of non-uniform classification practices in breast cancer with non-inflammatory skin involvement: a clinicopathologic study and an international survey.
Güth U, Singer G, Schötzau A, Langer I, Dieterich H, Rochlitz C, Herberich L, Holzgreve W, Wight E
Ann Oncol 2005 Oct;16(10):1618-23. Epub 2005 Jul 20 doi: 10.1093/annonc/mdi319. PMID: 16033873

Diagnosis

Delayed breast reconstruction with tram-flap and various modifications after radical mastectomy.
Smolanka II, Bagmut IY, Sheremet MI, Lyashenko AO, Movchan OV, Smolanka II Jr, Loboda AD, Kolisnyk IL, Sydorchuk LP, Lazaruk OV
J Med Life 2021 Nov-Dec;14(6):847-852. doi: 10.25122/jml-2021-0354. PMID: 35126757Free PMC Article
Characteristics and treatment modalities for African American women diagnosed with stage III breast cancer.
Rizzo M, Lund MJ, Mosunjac M, Bumpers H, Holmes L, O'Regan R, Brawley OW, Gabram S
Cancer 2009 Jul 1;115(13):3009-15. doi: 10.1002/cncr.24334. PMID: 19466698
Scope and significance of non-uniform classification practices in breast cancer with non-inflammatory skin involvement: a clinicopathologic study and an international survey.
Güth U, Singer G, Schötzau A, Langer I, Dieterich H, Rochlitz C, Herberich L, Holzgreve W, Wight E
Ann Oncol 2005 Oct;16(10):1618-23. Epub 2005 Jul 20 doi: 10.1093/annonc/mdi319. PMID: 16033873
Preoperative therapy in breast cancer: lessons from the treatment of locally advanced disease.
Wolff AC, Davidson NE
Oncologist 2002;7(3):239-45. doi: 10.1634/theoncologist.7-3-239. PMID: 12065797
Locally advanced breast cancer.
Sikov WM
Curr Treat Options Oncol 2000 Aug;1(3):228-38. doi: 10.1007/s11864-000-0034-9. PMID: 12057165

Therapy

Locally advanced breast cancer.
Aebi S, Karlsson P, Wapnir IL
Breast 2022 Mar;62 Suppl 1(Suppl 1):S58-S62. Epub 2021 Dec 15 doi: 10.1016/j.breast.2021.12.011. PMID: 34930650Free PMC Article
Management of locally advanced breast cancer. Mini-review.
Franceschini G, Terribile D, Fabbri C, Magno S, D'Alba P, Chiesa F, Di Leone A, Masetti R
Minerva Chir 2007 Aug;62(4):249-55. PMID: 17641585
Preoperative therapy in breast cancer: lessons from the treatment of locally advanced disease.
Wolff AC, Davidson NE
Oncologist 2002;7(3):239-45. doi: 10.1634/theoncologist.7-3-239. PMID: 12065797
Locally advanced breast cancer.
Sikov WM
Curr Treat Options Oncol 2000 Aug;1(3):228-38. doi: 10.1007/s11864-000-0034-9. PMID: 12057165
Primary chemotherapy for early and advanced breast cancer.
Hortobagyi GN, Buzdar AU, Strom EA, Ames FC, Singletary SE
Cancer Lett 1995 Mar 23;90(1):103-9. doi: 10.1016/0304-3835(94)03684-b. PMID: 7720036

Prognosis

Features of VEGF and IL-6 expression in patients with inflammatory breast cancer considering molecular-biological characteristics.
Smolanka II, Bagmut IY, Movchan OV, Sheremet MI, Bilyi OM, Lyashenko AO, Dosenko IV, Loboda AD, Ivankova OM, Kolisnyk IL
J Med Life 2023 Jan;16(1):153-159. doi: 10.25122/jml-2022-0172. PMID: 36873124Free PMC Article
Triple negative phenotype and N-ratio are important for prognosis in patients with stage IIIB non-inflammatory breast carcinoma.
Mersin H, Yildirim E, Berberoglu U, Gulben K
J Surg Oncol 2009 Dec 15;100(8):681-7. doi: 10.1002/jso.21411. PMID: 19798691
Management of locally advanced breast cancer. Mini-review.
Franceschini G, Terribile D, Fabbri C, Magno S, D'Alba P, Chiesa F, Di Leone A, Masetti R
Minerva Chir 2007 Aug;62(4):249-55. PMID: 17641585
Locally advanced breast cancer.
Sikov WM
Curr Treat Options Oncol 2000 Aug;1(3):228-38. doi: 10.1007/s11864-000-0034-9. PMID: 12057165
Primary chemotherapy for early and advanced breast cancer.
Hortobagyi GN, Buzdar AU, Strom EA, Ames FC, Singletary SE
Cancer Lett 1995 Mar 23;90(1):103-9. doi: 10.1016/0304-3835(94)03684-b. PMID: 7720036

Clinical prediction guides

Relationships Between Serum Cortisol, RAGE-Associated s100A8/A9 Levels, and Self-Reported Cancer-Related Distress in Women With Nonmetastatic Breast Cancer.
Taub CJ, Diaz A, Blomberg BB, Jutagir DR, Fisher HM, Gudenkauf LM, Lippman ME, Hudson BI, Antoni MH
Psychosom Med 2022 Sep 1;84(7):803-807. Epub 2022 Jul 28 doi: 10.1097/PSY.0000000000001109. PMID: 35980780Free PMC Article
Clinical and pathological response to induction chemotherapy used as a prognostic factor in inflammatory breast cancer. Single institution experience.
Kolarevic D, Tomasevic Z, Dzodic R, Gavrilovic D, Zegarac M
J BUON 2012 Jan-Mar;17(1):21-6. PMID: 22517688
Differences in survival among women with stage III inflammatory and noninflammatory locally advanced breast cancer appear early: a large population-based study.
Dawood S, Ueno NT, Valero V, Woodward WA, Buchholz TA, Hortobagyi GN, Gonzalez-Angulo AM, Cristofanilli M
Cancer 2011 May 1;117(9):1819-26. Epub 2010 Nov 29 doi: 10.1002/cncr.25682. PMID: 21509759
Inflammatory breast cancer as a model disease to study tumor angiogenesis: results of a phase IB trial of combination SU5416 and doxorubicin.
Overmoyer B, Fu P, Hoppel C, Radivoyevitch T, Shenk R, Persons M, Silverman P, Robertson K, Ziats NP, Wasman JK, Abdul-Karim FW, Jesberger JA, Duerk J, Hartman P, Hanks S, Lewin J, Dowlati A, McCrae K, Ivy P, Remick SC
Clin Cancer Res 2007 Oct 1;13(19):5862-8. doi: 10.1158/1078-0432.CCR-07-0688. PMID: 17908980
Results of mastectomy and postoperative irradiation in the management of locoregionally advanced carcinoma of the breast.
Strom EA, McNeese MD, Fletcher GH, Romsdahl MA, Montague ED, Oswald MJ
Int J Radiat Oncol Biol Phys 1991 Jul;21(2):319-23. doi: 10.1016/0360-3016(91)90777-2. PMID: 2061108

Recent systematic reviews

Clinical practice guidelines for the care and treatment of breast cancer: 15. Treatment for women with stage III or locally advanced breast cancer.
Shenkier T, Weir L, Levine M, Olivotto I, Whelan T, Reyno L; Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer
CMAJ 2004 Mar 16;170(6):983-94. doi: 10.1503/cmaj.1030944. PMID: 15023926Free PMC Article

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