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Abducens nerve neoplasm

MedGen UID:
224732
•Concept ID:
C1263898
•
Neoplastic Process
Synonyms: Abducens Nerve Neoplasm; abducens nerve neoplasm; abducens nerve neoplasm (disease); Abducens Nerve Neoplasms; abducens nerve neoplasms; Abducens Nerve Tumor; abducens nerve tumor; Abducens Nerve Tumors; abducens nerve tumors; abducens nerve tumour; abducens nerve tumours; Neoplasm of abducens nerve; Neoplasm of Abducens Nerve; neoplasm of abducens nerve; Neoplasm of Sixth Cranial Nerve; neoplasm of sixth cranial nerve; Neoplasm of the Abducens Nerve; neoplasm of the abducens nerve; Neoplasm of the Sixth Cranial Nerve; neoplasm of the sixth cranial nerve; Sixth Cranial Nerve Neoplasm; sixth cranial nerve neoplasm; Sixth Cranial Nerve Neoplasms; sixth cranial nerve neoplasms; Sixth Cranial Nerve Tumor; sixth cranial nerve tumor; Sixth Cranial Nerve Tumors; sixth cranial nerve tumors; sixth cranial nerve tumour; sixth cranial nerve tumours; Tumor of Abducens Nerve; tumor of abducens nerve; Tumor of Sixth Cranial Nerve; tumor of sixth cranial nerve; Tumor of the Abducens Nerve; tumor of the abducens nerve; Tumor of the Sixth Cranial Nerve; tumor of the sixth cranial nerve; tumour of abducens nerve; tumour of sixth cranial nerve; tumour of the abducens nerve; tumour of the sixth cranial nerve; VIth Cranial Nerve Neoplasms; VIth cranial nerve neoplasms; VIth Cranial Nerve Tumors; VIth cranial nerve tumors; VIth cranial nerve tumours
SNOMED CT: Neoplasm of abducens nerve (126972009)
 
Monarch Initiative: MONDO:0001884

Definition

A neoplasm involving a abducens nerve. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbducens nerve neoplasm

Professional guidelines

PubMed

Ocular Neuromyotonia in Children and Adolescents Following Radiation Treatment of Pediatric Brain Tumors.
Richardson C, Smith C, Merchant T, Khan R, Hoehn ME
J Pediatr Ophthalmol Strabismus 2022 Sep-Oct;59(5):338-343. Epub 2022 Feb 22 doi: 10.3928/01913913-20220124-01. PMID: 35192380
The spectrum and differential diagnosis of acquired ocular motor nerve palsies: a clinical study of 502 patients.
Hörner R, Kassubek J, Dreyhaupt J, Ludolph AC
J Neurol 2022 Apr;269(4):2140-2148. Epub 2021 Sep 19 doi: 10.1007/s00415-021-10761-w. PMID: 34537871Free PMC Article
Gamma Knife radiosurgery in the treatment of abducens nerve schwannomas: a retrospective study.
Prasad GL, Sharma MS, Kale SS, Agrawal D, Singh M, Sharma BS
J Neurosurg 2016 Oct;125(4):832-837. Epub 2016 Jan 29 doi: 10.3171/2015.8.JNS151140. PMID: 26824380

Recent clinical studies

Etiology

Clinical outcomes and etiology of acquired sixth cranial nerve palsy.
Oh SY
Medicine (Baltimore) 2022 Mar 18;101(11) doi: 10.1097/MD.0000000000029102. PMID: 35356946Free PMC Article
Sixth Nerve Palsy in Children Etiology, Long-Term Course, and a Diagnostic Algorithm.
Hanna FA, Jabaly-Habib H, Halachmi-Eyal O, Hujierat M, Sakran W, Spiegel R
J Child Neurol 2022 Mar;37(4):281-287. Epub 2021 Dec 8 doi: 10.1177/08830738211035912. PMID: 34879720
Etiology and Outcomes of Acquired Pediatric Sixth Nerve Palsies.
Chang MY, Borchert MS
J Neuroophthalmol 2022 Mar 1;42(1):e254-e259. Epub 2021 Aug 17 doi: 10.1097/WNO.0000000000001390. PMID: 34417775
Isolated third, fourth, and sixth cranial nerve palsies from presumed microvascular versus other causes: a prospective study.
Tamhankar MA, Biousse V, Ying GS, Prasad S, Subramanian PS, Lee MS, Eggenberger E, Moss HE, Pineles S, Bennett J, Osborne B, Volpe NJ, Liu GT, Bruce BB, Newman NJ, Galetta SL, Balcer LJ
Ophthalmology 2013 Nov;120(11):2264-9. Epub 2013 Jun 6 doi: 10.1016/j.ophtha.2013.04.009. PMID: 23747163Free PMC Article
Malignant peripheral nerve sheath tumor of the abducens nerve and a review of the literature.
Voorhies J, Hattab EM, Cohen-Gadol AA
World Neurosurg 2013 Nov;80(5):654.e1-8. Epub 2012 Sep 25 doi: 10.1016/j.wneu.2012.08.007. PMID: 23022650

Diagnosis

Neuro-Ophthalmic Manifestations of Acute Leukemia.
Alrobaian MA, Henderson AD
J Neuroophthalmol 2021 Dec 1;41(4):e584-e590. doi: 10.1097/WNO.0000000000001071. PMID: 32868572
Imaging Spectrum of Cavernous Sinus Lesions with Histopathologic Correlation.
Mahalingam HV, Mani SE, Patel B, Prabhu K, Alexander M, Fatterpekar GM, Chacko G
Radiographics 2019 May-Jun;39(3):795-819. Epub 2019 Apr 12 doi: 10.1148/rg.2019180122. PMID: 30978149
Imaging of Ocular Motor Pathway.
Tantiwongkosi B, Hesselink JR
Neuroimaging Clin N Am 2015 Aug;25(3):425-38. doi: 10.1016/j.nic.2015.05.006. PMID: 26208418
Isolated third, fourth, and sixth cranial nerve palsies from presumed microvascular versus other causes: a prospective study.
Tamhankar MA, Biousse V, Ying GS, Prasad S, Subramanian PS, Lee MS, Eggenberger E, Moss HE, Pineles S, Bennett J, Osborne B, Volpe NJ, Liu GT, Bruce BB, Newman NJ, Galetta SL, Balcer LJ
Ophthalmology 2013 Nov;120(11):2264-9. Epub 2013 Jun 6 doi: 10.1016/j.ophtha.2013.04.009. PMID: 23747163Free PMC Article
Neuro-ophthalmology.
Thompson HS
Arch Ophthalmol 1971 Oct;86(4):462-82. doi: 10.1001/archopht.1971.01000010464021. PMID: 4329269

Therapy

Hypophysitis - A Review of Fourteen Cases.
Chatterjee S, Chatterjee S, Bhartiya S
Neurol India 2023 Jan-Feb;71(1):119-121. doi: 10.4103/0028-3886.370481. PMID: 36861584
Factors Associated With Abducens Nerve Palsy in Patients Undergoing Surgery for Petroclival Meningiomas.
Yoo J, Lim SH, Jung IH, Park HH, Han J, Hong CK
J Neuroophthalmol 2022 Mar 1;42(1):e209-e216. Epub 2021 Dec 28 doi: 10.1097/WNO.0000000000001473. PMID: 34974485
Radiosurgery in trochlear and abducens nerve schwannomas: case series and systematic review.
Peciu-Florianu I, Tuleasca C, Comps JN, Schiappacasse L, Zeverino M, Daniel RT, Levivier M
Acta Neurochir (Wien) 2017 Dec;159(12):2409-2418. Epub 2017 Oct 11 doi: 10.1007/s00701-017-3348-0. PMID: 29022157
Abducens palsy after lumbar drain placement: a rare complication in endoscopic skull base surgery.
Cain RB, Patel NP, Hoxworth JM, Lal D
Laryngoscope 2013 Nov;123(11):2633-8. Epub 2013 May 13 doi: 10.1002/lary.24177. PMID: 23670572
Neuro-ophthalmology.
Thompson HS
Arch Ophthalmol 1971 Oct;86(4):462-82. doi: 10.1001/archopht.1971.01000010464021. PMID: 4329269

Prognosis

Factors Associated With Abducens Nerve Palsy in Patients Undergoing Surgery for Petroclival Meningiomas.
Yoo J, Lim SH, Jung IH, Park HH, Han J, Hong CK
J Neuroophthalmol 2022 Mar 1;42(1):e209-e216. Epub 2021 Dec 28 doi: 10.1097/WNO.0000000000001473. PMID: 34974485
Neuro-Ophthalmic Manifestations of Acute Leukemia.
Alrobaian MA, Henderson AD
J Neuroophthalmol 2021 Dec 1;41(4):e584-e590. doi: 10.1097/WNO.0000000000001071. PMID: 32868572
Abducens Nerve Schwannoma: A Case Report and Literature Review.
Nakamizo A, Matsuo S, Amano T
World Neurosurg 2019 May;125:49-54. Epub 2019 Feb 1 doi: 10.1016/j.wneu.2019.01.123. PMID: 30716483
Malignant peripheral nerve sheath tumor of the abducens nerve and a review of the literature.
Voorhies J, Hattab EM, Cohen-Gadol AA
World Neurosurg 2013 Nov;80(5):654.e1-8. Epub 2012 Sep 25 doi: 10.1016/j.wneu.2012.08.007. PMID: 23022650
Gamma Knife radiosurgery of cavernous sinus meningiomas: an institutional review.
Zeiler FA, McDonald PJ, Kaufmann AM, Fewer D, Butler J, Schroeder G, West M
Can J Neurol Sci 2012 Nov;39(6):757-62. doi: 10.1017/s0317167100015572. PMID: 23230622

Clinical prediction guides

Factors Associated With Abducens Nerve Palsy in Patients Undergoing Surgery for Petroclival Meningiomas.
Yoo J, Lim SH, Jung IH, Park HH, Han J, Hong CK
J Neuroophthalmol 2022 Mar 1;42(1):e209-e216. Epub 2021 Dec 28 doi: 10.1097/WNO.0000000000001473. PMID: 34974485
Endoscopic endonasal transmaxillary-pterygoid approach for skull-base non-vestibular schwannomas in 10 consecutive patients.
Morinaga Y, Akutsu H, Kino H, Hara T, Tanaka S, Miyamoto H, Matsuda M, Ishikawa E
Acta Neurochir (Wien) 2022 Feb;164(2):331-341. Epub 2021 Nov 23 doi: 10.1007/s00701-021-05068-8. PMID: 34812948
A clinical study of ocular motor nerve functions after petroclival meningioma resection.
Wang L, Zhang Q, Weng JC, Chen LP, Li D, Jia GJ, Zhang LW, Wu Z, Jia W, Zhang JT
Acta Neurochir (Wien) 2020 Jun;162(6):1249-1257. Epub 2020 Feb 26 doi: 10.1007/s00701-020-04262-4. PMID: 32100111
Möbius syndrome with cardiac rhabdomyomas.
Verner A, Agarwal-Sinha S, Han FY
Ophthalmic Genet 2018 Jun;39(3):373-376. Epub 2018 Jan 16 doi: 10.1080/13816810.2017.1423336. PMID: 29336632
Isolated third, fourth, and sixth cranial nerve palsies from presumed microvascular versus other causes: a prospective study.
Tamhankar MA, Biousse V, Ying GS, Prasad S, Subramanian PS, Lee MS, Eggenberger E, Moss HE, Pineles S, Bennett J, Osborne B, Volpe NJ, Liu GT, Bruce BB, Newman NJ, Galetta SL, Balcer LJ
Ophthalmology 2013 Nov;120(11):2264-9. Epub 2013 Jun 6 doi: 10.1016/j.ophtha.2013.04.009. PMID: 23747163Free PMC Article

Recent systematic reviews

Metastatic Lesions of the Clivus: A Systematic Review.
Jozsa F, Das JM
World Neurosurg 2022 Feb;158:190-204. Epub 2021 Nov 30 doi: 10.1016/j.wneu.2021.11.105. PMID: 34861450
Cranial Nerve Disorders Associated With Immune Checkpoint Inhibitors.
Vogrig A, Muñiz-Castrillo S, Joubert B, Picard G, Rogemond V, Skowron F, Egri M, Desestret V, Tilikete C, Psimaras D, Ducray F, Honnorat J
Neurology 2021 Feb 9;96(6):e866-e875. Epub 2020 Dec 14 doi: 10.1212/WNL.0000000000011340. PMID: 33318162
Radiosurgery in trochlear and abducens nerve schwannomas: case series and systematic review.
Peciu-Florianu I, Tuleasca C, Comps JN, Schiappacasse L, Zeverino M, Daniel RT, Levivier M
Acta Neurochir (Wien) 2017 Dec;159(12):2409-2418. Epub 2017 Oct 11 doi: 10.1007/s00701-017-3348-0. PMID: 29022157
Factors Associated with Abducens Nerve Recovery in Patients Undergoing Surgical Resection of Sixth Nerve Schwannoma: A Systematic Review and Case Illustration.
Sun H, Sharma K, Kalakoti P, Thakur JD, Patra DP, Konar S, Maiti T, Akbarian-Tefaghi H, Bollam P, Notarianni C, Nanda A
World Neurosurg 2017 Aug;104:883-899. Epub 2017 Apr 29 doi: 10.1016/j.wneu.2017.04.146. PMID: 28465275
Abducens palsy after lumbar drain placement: a rare complication in endoscopic skull base surgery.
Cain RB, Patel NP, Hoxworth JM, Lal D
Laryngoscope 2013 Nov;123(11):2633-8. Epub 2013 May 13 doi: 10.1002/lary.24177. PMID: 23670572

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