U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Spindle cell hemangioma

MedGen UID:
224916
Concept ID:
C1304508
Neoplastic Process
Synonyms: SCh; Spindle -Cell Hemangioma; spindle -cell hemangioma; Spindle cell angioendothelioma; Spindle cell hemangioendothelioma; Spindle Cell Hemangioendothelioma; spindle cell hemangioendothelioma; Spindle Cell Hemangioma; spindle cell hemangioma
SNOMED CT: Spindle cell hemangioma (403967000); Spindle cell angioendothelioma (128769003); Spindle cell hemangioendothelioma (128769003); Spindle cell hemangioma (128769003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0016222
Orphanet: ORPHA210584

Definition

Spindle cell hemangioma (SCH), also known as spindle cell hemangioendothelioma, is a rare benign vascular tumor either solitary or multiple, characterized by cavernous blood vessels separated by spindle cells reminiscent of those in Kaposi?s sarcoma and located in the dermis and subcutis. [from ORDO]

Professional guidelines

PubMed

Putra J, Gupta A
Pathology 2017 Jun;49(4):356-362. Epub 2017 Apr 21 doi: 10.1016/j.pathol.2017.03.001. PMID: 28438388
Suster S
Semin Diagn Pathol 1995 May;12(2):140-57. PMID: 7638447
Nishimura K, Hida S, Okada K, Yoshida O, Nishimuara K
Hinyokika Kiyo 1988 Aug;34(8):1323-31. PMID: 3195400

Recent clinical studies

Etiology

Brown NJ, Ye Z, Stutterd C, Jayasinghe SI, Schneider A, Mullen S, Mandelstam SA, Hildebrand MS
Cold Spring Harb Mol Case Stud 2021 Dec;7(6) Epub 2021 Dec 9 doi: 10.1101/mcs.a006127. PMID: 34588213Free PMC Article
Papez J, Starha J, Zerhau P, Pavlovska D, Jezova M, Jurencak T, Slaba K, Sterba M, Kerekes A, Merta T, Haluskova T, Palova H, Slaby O, Sterba J, Jabandziev P
Genes (Basel) 2021 Feb 3;12(2) doi: 10.3390/genes12020220. PMID: 33546375Free PMC Article
Nasser R, Ashayeri K, Legatt AD, Houten JK
J Neurosurg Spine 2016 Sep;25(3):379-82. Epub 2016 Apr 8 doi: 10.3171/2015.11.SPINE15641. PMID: 27058496
Tomasini C, Aloi F, Soro E, Elia V
Dermatology 1999;199(3):274-6. doi: 10.1159/000018265. PMID: 10592415
Keel SB, Rosenberg AE
Cancer 1999 May 1;85(9):1966-72. doi: 10.1002/(sici)1097-0142(19990501)85:9<1966::aid-cncr13>3.0.co;2-w. PMID: 10223237

Diagnosis

Mansfield SA, Williams RF, Iacobas I
Semin Pediatr Surg 2020 Oct;29(5):150975. Epub 2020 Sep 16 doi: 10.1016/j.sempedsurg.2020.150975. PMID: 33069294
Habeeb O, Rubin BP
Surg Pathol Clin 2019 Mar;12(1):35-49. Epub 2018 Dec 4 doi: 10.1016/j.path.2018.10.002. PMID: 30709447
Marušić Z, Billings SD
Surg Pathol Clin 2017 Jun;10(2):345-366. Epub 2017 Mar 31 doi: 10.1016/j.path.2017.01.006. PMID: 28477885
Coras B, Hohenleutner U, Landthaler M, Hohenleutner S
Dermatol Surg 2003 Aug;29(8):875-8. doi: 10.1046/j.1524-4725.2003.29238.x. PMID: 12859394
Tomasini C, Aloi F, Soro E, Elia V
Dermatology 1999;199(3):274-6. doi: 10.1159/000018265. PMID: 10592415

Prognosis

Nasser R, Ashayeri K, Legatt AD, Houten JK
J Neurosurg Spine 2016 Sep;25(3):379-82. Epub 2016 Apr 8 doi: 10.3171/2015.11.SPINE15641. PMID: 27058496
Tsukamoto S, Honoki K, Shimada K, Fujii H, Kido A, Takano M, Enomoto Y, Kasai T, Konishi N, Tanaka Y
Skeletal Radiol 2013 Aug;42(8):1165-8. Epub 2013 Mar 24 doi: 10.1007/s00256-013-1603-x. PMID: 23525489
Miettinen M, Wang ZF
Am J Surg Pathol 2012 Mar;36(3):351-9. doi: 10.1097/PAS.0b013e318236c312. PMID: 22067331Free PMC Article
Perkins P, Weiss SW
Am J Surg Pathol 1996 Oct;20(10):1196-204. doi: 10.1097/00000478-199610000-00004. PMID: 8827025

Clinical prediction guides

Gao BQ, Zhou DK, Qian XH, Zhang W, Ying LX, Wang WL
Medicine (Baltimore) 2019 Mar;98(9):e14555. doi: 10.1097/MD.0000000000014555. PMID: 30817572Free PMC Article
Miettinen M, Wang ZF
Am J Surg Pathol 2012 Mar;36(3):351-9. doi: 10.1097/PAS.0b013e318236c312. PMID: 22067331Free PMC Article
Fukunaga M, Suzuki K, Saegusa N, Folpe AL
Am J Surg Pathol 2007 Oct;31(10):1567-72. doi: 10.1097/PAS.0b013e318038f6b5. PMID: 17895759
Reis-Filho JS, Paiva ME, Lopes JM
J Cutan Pathol 2002 Apr;29(4):226-31. doi: 10.1034/j.1600-0560.2002.290405.x. PMID: 12028155

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...