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Benign Mediastinal Soft Tissue Neoplasm

MedGen UID:
231938
Concept ID:
C1332516
Neoplastic Process
Synonyms: Benign Soft Tissue Mediastinal Tumor; Benign Soft Tissue Neoplasm of Mediastinum; Benign Soft Tissue Neoplasm of the Mediastinum; Benign Soft Tissue Tumor of Mediastinum; Benign Soft Tissue Tumor of the Mediastinum

Definition

A mesenchymal neoplasm that arises from the mediastinum and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include lipoma, leiomyoma, and rhabdomyoma. [from NCI]

Professional guidelines

PubMed

Kim JH, Choe J, Kim HK, Lee HY
Korean J Radiol 2023 Jan;24(1):62-78. doi: 10.3348/kjr.2022.0606. PMID: 36606621Free PMC Article
Kozol RA, Geelhoed GW, Flynn SD, Kinder B
Surgery 1993 Dec;114(6):1103-6; discussion 1106-7. PMID: 8256214
Siegel MJ, Sagel SS, Reed K
Radiology 1982 Jan;142(1):149-55. doi: 10.1148/radiology.142.1.7053524. PMID: 7053524

Recent clinical studies

Etiology

Kaur K, Patel T, Patra S, Trivedi P
Acta Cytol 2023;67(4):333-345. Epub 2022 Dec 29 doi: 10.1159/000528843. PMID: 36580900
Deka JB, Shah MVK, Shah R, Bhatnagar N, Bortolotto C, Jiménez F
J Ultrasound 2023 Mar;26(1):295-300. Epub 2022 Sep 24 doi: 10.1007/s40477-022-00727-7. PMID: 36152213Free PMC Article
Mehta A, Davey J, Gharpuray-Pandit D, Plaza JA, Billings SD, Balogh P, Tchrakian N, Selvan S, Wiedemeyer K, Hornick JL, Brenn T
Am J Surg Pathol 2022 Sep 1;46(9):1241-1249. Epub 2022 Mar 31 doi: 10.1097/PAS.0000000000001896. PMID: 35354162
Creytens D
Virchows Arch 2020 Jan;476(1):29-39. Epub 2019 Sep 9 doi: 10.1007/s00428-019-02652-3. PMID: 31501988
Kerkeni Y, Sahnoun L, Ksia A, Hidouri S, Chahed J, Krichen I, Mekki M, Belghith M, Nouri A
Afr J Paediatr Surg 2014 Jan-Mar;11(1):32-4. doi: 10.4103/0189-6725.129210. PMID: 24647290

Diagnosis

Kim JH, Choe J, Kim HK, Lee HY
Korean J Radiol 2023 Jan;24(1):62-78. doi: 10.3348/kjr.2022.0606. PMID: 36606621Free PMC Article
Creytens D
Virchows Arch 2020 Jan;476(1):29-39. Epub 2019 Sep 9 doi: 10.1007/s00428-019-02652-3. PMID: 31501988
Marcus A, Narula N, Kamel MK, Koizumi J, Port JL, Stiles B, Moreira A, Altorki NK, Giorgadze T
Ann Diagn Pathol 2019 Apr;39:69-73. Epub 2019 Feb 10 doi: 10.1016/j.anndiagpath.2019.02.011. PMID: 30797131
Sonavane SK, Milner DM, Singh SP, Abdel Aal AK, Shahir KS, Chaturvedi A
Radiographics 2015 Nov-Dec;35(7):1873-92. Epub 2015 Oct 9 doi: 10.1148/rg.2015150056. PMID: 26452112
Patel RV, Evans K, Sau I, Huddart S
BMJ Case Rep 2014 May 20;2014 doi: 10.1136/bcr-2014-203585. PMID: 24849642Free PMC Article

Therapy

Araki T, Hammer M, Sodickson A
Curr Probl Diagn Radiol 2022 May-Jun;51(3):334-339. Epub 2021 Jul 15 doi: 10.1067/j.cpradiol.2021.06.007. PMID: 34364734
Prezerakos GK, Sayal P, Kourliouros A, Pericleous P, Ladas G, Casey A
Eur Spine J 2018 Apr;27(4):902-912. Epub 2018 Feb 14 doi: 10.1007/s00586-018-5512-5. PMID: 29445946
Jevremovic V, Yousuf A, Hussain Z, Abboud A, Chedrawy EG
J Med Case Rep 2017 Mar 7;11(1):61. doi: 10.1186/s13256-017-1223-5. PMID: 28264709Free PMC Article
Twigt BA, van Dalen T, Vroonhoven TJ, Consten EC
Acta Chir Belg 2013 May-Jun;113(3):228-32. doi: 10.1080/00015458.2013.11680918. PMID: 24941723
Demmy TL, Krasna MJ, Detterbeck FC, Kline GG, Kohman LJ, DeCamp MM Jr, Wain JC
Ann Thorac Surg 1998 Jul;66(1):187-92. doi: 10.1016/s0003-4975(98)00378-6. PMID: 9692462

Prognosis

Mehta A, Davey J, Gharpuray-Pandit D, Plaza JA, Billings SD, Balogh P, Tchrakian N, Selvan S, Wiedemeyer K, Hornick JL, Brenn T
Am J Surg Pathol 2022 Sep 1;46(9):1241-1249. Epub 2022 Mar 31 doi: 10.1097/PAS.0000000000001896. PMID: 35354162
Creytens D
Virchows Arch 2020 Jan;476(1):29-39. Epub 2019 Sep 9 doi: 10.1007/s00428-019-02652-3. PMID: 31501988
Gayer G
Semin Ultrasound CT MR 2017 Dec;38(6):629-633. Epub 2017 Aug 31 doi: 10.1053/j.sult.2017.08.003. PMID: 29179902
Patel RV, Evans K, Sau I, Huddart S
BMJ Case Rep 2014 May 20;2014 doi: 10.1136/bcr-2014-203585. PMID: 24849642Free PMC Article
Rosado-de-Christenson ML, Galobardes J, Moran CA
Radiographics 1992 Jan;12(1):151-68. doi: 10.1148/radiographics.12.1.1734461. PMID: 1734461

Clinical prediction guides

Yuan C, Fan J, Xu L
Medicine (Baltimore) 2023 Dec 15;102(50):e36558. doi: 10.1097/MD.0000000000036558. PMID: 38115338Free PMC Article
Mehta A, Davey J, Gharpuray-Pandit D, Plaza JA, Billings SD, Balogh P, Tchrakian N, Selvan S, Wiedemeyer K, Hornick JL, Brenn T
Am J Surg Pathol 2022 Sep 1;46(9):1241-1249. Epub 2022 Mar 31 doi: 10.1097/PAS.0000000000001896. PMID: 35354162
Hato T, Kashimada H, Yamaguchi M, Sugiyama A, Inoue Y, Aoki K, Fukuda H, Gika M, Kikuchi J, Fujino T, Yamaguchi T, Tamaru JI, Kohno M, Nakayama M
J Med Case Rep 2021 Oct 18;15(1):525. doi: 10.1186/s13256-021-03014-x. PMID: 34663426Free PMC Article
Xu T, Zhu W, Wang P
Medicine (Baltimore) 2019 Apr;98(15):e15203. doi: 10.1097/MD.0000000000015203. PMID: 30985715Free PMC Article
Gayer G
Semin Ultrasound CT MR 2017 Dec;38(6):629-633. Epub 2017 Aug 31 doi: 10.1053/j.sult.2017.08.003. PMID: 29179902

Recent systematic reviews

Treglia G, Giovannini E, Di Franco D, Calcagni ML, Rufini V, Picchio M, Giordano A
Ann Nucl Med 2012 Jul;26(6):451-61. Epub 2012 May 8 doi: 10.1007/s12149-012-0602-7. PMID: 22566040

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