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Gastric Inflammatory Myofibroblastic Tumor

MedGen UID:
232235
•Concept ID:
C1333774
•
Neoplastic Process
Synonyms: Gastric Inflammatory Myofibroblastic Neoplasm; Inflammatory Gastric Pseudotumor; Inflammatory Myofibroblastic Neoplasm of Stomach; Inflammatory Myofibroblastic Neoplasm of the Stomach; Inflammatory Myofibroblastic Tumor of Stomach; Inflammatory Myofibroblastic Tumor of the Stomach; Inflammatory Pseudotumor of Stomach; Inflammatory Pseudotumor of the Stomach

Definition

A multinodular intermediate fibroblastic neoplasm arising from the stomach. It is characterized by the presence of spindle-shaped fibroblasts and myofibroblasts, and a chronic inflammatory infiltrate composed of eosinophils, lymphocytes and plasma cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastric Inflammatory Myofibroblastic Tumor

Professional guidelines

PubMed

Utility of immunohistochemical investigation of SDHB and molecular genetic analysis of SDH genes in the differential diagnosis of mesenchymal tumors of GIT.
Dubova M, Sedivcova M, Michal M, Kokoskova B, Ryska A, Smid D, Daum O
Histol Histopathol 2015 Feb;30(2):223-32. Epub 2014 Sep 10 doi: 10.14670/HH-30.223. PMID: 25205505
Inflammatory myofibroblastic tumor in children: diagnosis and treatment.
Karnak I, Senocak ME, Ciftci AO, Cağlar M, Bingöl-Koloğlu M, Tanyel FC, Büyükpamukçu N
J Pediatr Surg 2001 Jun;36(6):908-12. doi: 10.1053/jpsu.2001.23970. PMID: 11381424
Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT).
Miettinen M, Sobin LH, Sarlomo-Rikala M
Mod Pathol 2000 Oct;13(10):1134-42. doi: 10.1038/modpathol.3880210. PMID: 11048809

Recent clinical studies

Etiology

Primary gastric myofibroblastic tumor in an adult at Perú: Case report and literature review.
Flores-Trujillo GA, Abad-Licham M, Casavilca-Zambrano S, Valencia-Mariñas H, Astigueta-Pérez J, Díaz-Plasencia J
Medwave 2022 Nov 23;22(10):e2529. doi: 10.5867/medwave.2022.10.2529. PMID: 36583602

Diagnosis

Primary gastric myofibroblastic tumor in an adult at Perú: Case report and literature review.
Flores-Trujillo GA, Abad-Licham M, Casavilca-Zambrano S, Valencia-Mariñas H, Astigueta-Pérez J, Díaz-Plasencia J
Medwave 2022 Nov 23;22(10):e2529. doi: 10.5867/medwave.2022.10.2529. PMID: 36583602
Primary gastric inflammatory myofibroblastic tumor: A case report.
Cheng B, Yang C, Liu Z, Liu L, Zhou L
Medicine (Baltimore) 2018 Dec;97(50):e13423. doi: 10.1097/MD.0000000000013423. PMID: 30557996Free PMC Article
Gastric inflammatory myofibroblastic tumor treated with combined laparoscopic and endoscopic gastric wedge resection: a case report.
Hayashi M, Kawakubo H, Mayanagi S, Nakamura R, Suda K, Wada N, Kitagawa Y
World J Surg Oncol 2018 Aug 8;16(1):161. doi: 10.1186/s12957-018-1460-0. PMID: 30089486Free PMC Article
ALK-positive gastric inflammatory myofibroblastic tumor in an adult with familial adenomatous polyposis and diffuse fundic polyposis.
Fan J, Huang B, Yang X, Yang M, He J, Nie X
Diagn Pathol 2017 Sep 18;12(1):68. doi: 10.1186/s13000-017-0645-0. PMID: 28923119Free PMC Article
Fever of unknown origin as a presentation of gastric inflammatory myofibroblastic tumor in a two-year-old boy.
Cho MY, Min YK, Kim NR, Cho SJ, Kim HK, Lee KC, Suh SO, Whang CW
J Korean Med Sci 2002 Oct;17(5):699-703. doi: 10.3346/jkms.2002.17.5.699. PMID: 12378027Free PMC Article

Prognosis

Gastric inflammatory myofibroblastic tumor treated with combined laparoscopic and endoscopic gastric wedge resection: a case report.
Hayashi M, Kawakubo H, Mayanagi S, Nakamura R, Suda K, Wada N, Kitagawa Y
World J Surg Oncol 2018 Aug 8;16(1):161. doi: 10.1186/s12957-018-1460-0. PMID: 30089486Free PMC Article
Fever of unknown origin as a presentation of gastric inflammatory myofibroblastic tumor in a two-year-old boy.
Cho MY, Min YK, Kim NR, Cho SJ, Kim HK, Lee KC, Suh SO, Whang CW
J Korean Med Sci 2002 Oct;17(5):699-703. doi: 10.3346/jkms.2002.17.5.699. PMID: 12378027Free PMC Article

Clinical prediction guides

Primary gastric inflammatory myofibroblastic tumor: a clinicopathologic and immunohistochemical study of 5 cases.
Shi H, Wei L, Sun L, Guo A
Pathol Res Pract 2010 May 15;206(5):287-91. Epub 2010 Mar 20 doi: 10.1016/j.prp.2009.09.002. PMID: 20304564

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