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Rectosigmoid carcinoma

MedGen UID:
232963
•Concept ID:
C1327709
•
Neoplastic Process
Synonyms: carcinoma of rectosigmoid junction; Rectosigmoid Cancer; rectosigmoid cancer; Rectosigmoid Carcinoma; rectosigmoid carcinoma; rectosigmoid junction carcinoma
 
Monarch Initiative: MONDO:0002424

Definition

A malignant epithelial neoplasm that arises from the rectosigmoid area and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas. About 50% of colorectal carcinomas occur in the rectosigmoid area. [from NCI]

Professional guidelines

PubMed

Intraoperative electron beam radiation therapy for primary locally advanced rectal and rectosigmoid carcinoma.
Willett CG, Shellito PC, Tepper JE, Eliseo R, Convery K, Wood WC
J Clin Oncol 1991 May;9(5):843-9. doi: 10.1200/JCO.1991.9.5.843. PMID: 2016628
Technique of postoperative pelvic radiation in the management of rectal and rectosigmoid carcinoma.
Kumar PP, Good RR, Plantz SH, Hynes PR
J Natl Med Assoc 1987 Jun;79(6):609-15. PMID: 3112415Free PMC Article
Palliative treatment of rectosigmoid carcinoma by laser endoscopic photoablation.
Brunetaud JM, Maunoury V, Ducrotte P, Cochelard D, Cortot A, Paris JC
Gastroenterology 1987 Mar;92(3):663-8. doi: 10.1016/0016-5085(87)90015-1. PMID: 2434382

Recent clinical studies

Etiology

Sigmoid take-off in rectosigmoid cancer as a landmark identifying benefit from neoadjuvant chemoradiation: A retrospective comparative cohort study.
Li F, Qu R, Meng Y, Li N, Chen M, Wang H, Zhou X, Fu W
Asian J Surg 2023 Oct;46(10):4330-4336. Epub 2022 Oct 28 doi: 10.1016/j.asjsur.2022.10.031. PMID: 37803809
Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.
Feng H, Lu AG, Zhao XW, Han DP, Zhao JK, Shi L, Schiergens TS, Lee SM, Zhang WP, Thasler WE
World J Gastroenterol 2015 Jun 21;21(23):7225-32. doi: 10.3748/wjg.v21.i23.7225. PMID: 26109809Free PMC Article
Pyoderma gangrenosum associated with solid organ malignancies.
Shahi V, Wetter DA
Int J Dermatol 2015 Sep;54(9):e351-7. Epub 2015 Mar 13 doi: 10.1111/ijd.12796. PMID: 25773911
Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial.
Leung KL, Kwok SP, Lam SC, Lee JF, Yiu RY, Ng SS, Lai PB, Lau WY
Lancet 2004 Apr 10;363(9416):1187-92. doi: 10.1016/S0140-6736(04)15947-3. PMID: 15081650
Lymphocyte subsets and natural killer cell cytotoxicity after laparoscopically assisted resection of rectosigmoid carcinoma.
Leung KL, Tsang KS, Ng MH, Leung KJ, Lai PB, Lee JF, Lau WY
Surg Endosc 2003 Aug;17(8):1305-10. Epub 2003 May 6 doi: 10.1007/s00464-002-9172-4. PMID: 12728374

Diagnosis

Sigmoid take-off in rectosigmoid cancer as a landmark identifying benefit from neoadjuvant chemoradiation: A retrospective comparative cohort study.
Li F, Qu R, Meng Y, Li N, Chen M, Wang H, Zhou X, Fu W
Asian J Surg 2023 Oct;46(10):4330-4336. Epub 2022 Oct 28 doi: 10.1016/j.asjsur.2022.10.031. PMID: 37803809
Case of rectosigmoid carcinoma and incidental pelvic kidney.
Zhu KJ, Warrier SK
ANZ J Surg 2020 May;90(5):886-888. Epub 2019 Jul 23 doi: 10.1111/ans.15340. PMID: 31334589
Rectosigmoid carcinoma presenting as full-thickness rectal prolapse.
Montwedi D
BMJ Case Rep 2019 Dec 30;12(12) doi: 10.1136/bcr-2019-230409. PMID: 31892618Free PMC Article
Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.
Feng H, Lu AG, Zhao XW, Han DP, Zhao JK, Shi L, Schiergens TS, Lee SM, Zhang WP, Thasler WE
World J Gastroenterol 2015 Jun 21;21(23):7225-32. doi: 10.3748/wjg.v21.i23.7225. PMID: 26109809Free PMC Article
Masses simulating gynecologic diseases at CT and MR imaging.
Foshager MC, Hood LL, Walsh JW
Radiographics 1996 Sep;16(5):1085-99. doi: 10.1148/radiographics.16.5.8888392. PMID: 8888392

Therapy

Effect of general practitioner-led versus surgeon-led colon cancer survivorship care, with or without eHealth support, on quality of life (I CARE): an interim analysis of 1-year results of a randomised, controlled trial.
Vos JAM, Duineveld LAM, Wieldraaijer T, Wind J, Busschers WB, Sert E, Tanis PJ, Verdonck-de Leeuw IM, van Weert HCPM, van Asselt KM; I CARE study group
Lancet Oncol 2021 Aug;22(8):1175-1187. Epub 2021 Jul 2 doi: 10.1016/S1470-2045(21)00273-4. PMID: 34224671
CHYLOUS ASCITES AFTER LAPAROSCOPIC LOW ANTERIOR COLORECTAL RESECTION FOR RECTOSIGMOID CARCINOMA: A CASE REPORT AND A LITERATURE REVIEW.
Korkolis DP, Kapritsou M, Passas I, Kalafati M, Katsoulas T, Konstantinou EA
Gastroenterol Nurs 2017 Nov/Dec;40(6):504-509. doi: 10.1097/SGA.0000000000000318. PMID: 29210819
Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial.
Leung KL, Kwok SP, Lam SC, Lee JF, Yiu RY, Ng SS, Lai PB, Lau WY
Lancet 2004 Apr 10;363(9416):1187-92. doi: 10.1016/S0140-6736(04)15947-3. PMID: 15081650
Lymphocyte subsets and natural killer cell cytotoxicity after laparoscopically assisted resection of rectosigmoid carcinoma.
Leung KL, Tsang KS, Ng MH, Leung KJ, Lai PB, Lee JF, Lau WY
Surg Endosc 2003 Aug;17(8):1305-10. Epub 2003 May 6 doi: 10.1007/s00464-002-9172-4. PMID: 12728374
Intraoperative radiation therapy for locally advanced recurrent rectal or rectosigmoid cancer.
Lindel K, Willett CG, Shellito PC, Ott MJ, Clark J, Grossbard M, Ryan D, Ancukiewicz M
Radiother Oncol 2001 Jan;58(1):83-7. doi: 10.1016/s0167-8140(00)00309-1. PMID: 11165686

Prognosis

Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.
Feng H, Lu AG, Zhao XW, Han DP, Zhao JK, Shi L, Schiergens TS, Lee SM, Zhang WP, Thasler WE
World J Gastroenterol 2015 Jun 21;21(23):7225-32. doi: 10.3748/wjg.v21.i23.7225. PMID: 26109809Free PMC Article
Pyoderma gangrenosum associated with solid organ malignancies.
Shahi V, Wetter DA
Int J Dermatol 2015 Sep;54(9):e351-7. Epub 2015 Mar 13 doi: 10.1111/ijd.12796. PMID: 25773911
Comparison of hand-assisted laparoscopic surgery using tissue fusion devices and open resection for treatment of rectosigmoid carcinoma.
Zhu Y, Feng H, Li Q, Chen Y, Qian J, Liu Y, Li D
Surg Laparosc Endosc Percutan Tech 2014 Oct;24(5):e157-61. doi: 10.1097/SLE.0b013e3182a2b03e. PMID: 25090290
Paraneoplastic necrotizing myopathy and dermatomyositis in a patient with rectosigmoid carcinoma.
Samuels N, Applbaum YH, Esayag Y
Rheumatol Int 2013 Jun;33(6):1619-21. Epub 2011 Dec 25 doi: 10.1007/s00296-011-2304-1. PMID: 22198662
Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial.
Leung KL, Kwok SP, Lam SC, Lee JF, Yiu RY, Ng SS, Lai PB, Lau WY
Lancet 2004 Apr 10;363(9416):1187-92. doi: 10.1016/S0140-6736(04)15947-3. PMID: 15081650

Clinical prediction guides

Sigmoid take-off in rectosigmoid cancer as a landmark identifying benefit from neoadjuvant chemoradiation: A retrospective comparative cohort study.
Li F, Qu R, Meng Y, Li N, Chen M, Wang H, Zhou X, Fu W
Asian J Surg 2023 Oct;46(10):4330-4336. Epub 2022 Oct 28 doi: 10.1016/j.asjsur.2022.10.031. PMID: 37803809
Effect of general practitioner-led versus surgeon-led colon cancer survivorship care, with or without eHealth support, on quality of life (I CARE): an interim analysis of 1-year results of a randomised, controlled trial.
Vos JAM, Duineveld LAM, Wieldraaijer T, Wind J, Busschers WB, Sert E, Tanis PJ, Verdonck-de Leeuw IM, van Weert HCPM, van Asselt KM; I CARE study group
Lancet Oncol 2021 Aug;22(8):1175-1187. Epub 2021 Jul 2 doi: 10.1016/S1470-2045(21)00273-4. PMID: 34224671
Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.
Feng H, Lu AG, Zhao XW, Han DP, Zhao JK, Shi L, Schiergens TS, Lee SM, Zhang WP, Thasler WE
World J Gastroenterol 2015 Jun 21;21(23):7225-32. doi: 10.3748/wjg.v21.i23.7225. PMID: 26109809Free PMC Article
Comparison of hand-assisted laparoscopic surgery using tissue fusion devices and open resection for treatment of rectosigmoid carcinoma.
Zhu Y, Feng H, Li Q, Chen Y, Qian J, Liu Y, Li D
Surg Laparosc Endosc Percutan Tech 2014 Oct;24(5):e157-61. doi: 10.1097/SLE.0b013e3182a2b03e. PMID: 25090290
Preoperative prediction of late cancer-specific deaths in patients with rectal and rectosigmoid carcinoma.
Ståhle E, Glimelius B, Bergström R, Påhlman L
Int J Colorectal Dis 1989 Aug;4(3):182-7. doi: 10.1007/BF01649701. PMID: 2769002

Recent systematic reviews

In search of a dose-response relationship with radiotherapy in the management of recurrent rectal carcinoma in the pelvis: a systematic review.
Wong R, Thomas G, Cummings B, Froud P, Shelley W, Withers R, Williams J
Int J Radiat Oncol Biol Phys 1998 Jan 15;40(2):437-46. doi: 10.1016/s0360-3016(97)00711-6. PMID: 9457833

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