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Metastatic Breast Squamous Cell Carcinoma

MedGen UID:
233188
•Concept ID:
C1334743
•
Neoplastic Process
Synonyms: Metastatic Squamous Cell Breast Carcinoma; Metastatic Squamous Cell Carcinoma of Breast; Metastatic Squamous Cell Carcinoma of the Breast

Definition

A squamous cell carcinoma that arises from the breast parenchyma and has metastasized to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Breast Squamous Cell Carcinoma

Professional guidelines

PubMed

Oligometastases in head and neck carcinoma and their impact on management.
Mat Lazim N, Elliott M, Wykes J, Clark J
ANZ J Surg 2021 Dec;91(12):2617-2623. Epub 2021 Feb 26 doi: 10.1111/ans.16622. PMID: 33634950
Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference.
Nicolai N, Biasoni D, Catanzaro MA, Colecchia M, Trama A; RARECAREnet Working Group
Eur J Surg Oncol 2019 Jan;45(1):60-66. Epub 2018 Feb 14 doi: 10.1016/j.ejso.2018.02.006. PMID: 29526370
Surgical management of lung metastases.
Patrini D, Panagiotopoulos N, Lawrence D, Scarci M
Br J Hosp Med (Lond) 2017 Apr 2;78(4):192-198. doi: 10.12968/hmed.2017.78.4.192. PMID: 28398890

Recent clinical studies

Etiology

Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial.
Oaknin A, Gladieff L, Martínez-García J, Villacampa G, Takekuma M, De Giorgi U, Lindemann K, Woelber L, Colombo N, Duska L, Leary A, Godoy-Ortiz A, Nishio S, Angelergues A, Rubio MJ, Fariñas-Madrid L, Yamaguchi S, Lorusso D, Ray-Coquard I, Manso L, Joly F, Alarcón J, Follana P, Romero I, Lebreton C, Pérez-Fidalgo JA, Yunokawa M, Dahlstrand H, D'Hondt V, Randall LM; ENGOT-Cx10–GEICO 68-C–JGOG1084–GOG-3030 Investigators
Lancet 2024 Jan 6;403(10421):31-43. Epub 2023 Dec 1 doi: 10.1016/S0140-6736(23)02405-4. PMID: 38048793
Sentinel lymph node biopsy and morbidity outcomes in early cervical cancer: Results of a multicentre randomised trial (SENTICOL-2).
Mathevet P, Lécuru F, Uzan C, Boutitie F, Magaud L, Guyon F, Querleu D, Fourchotte V, Baron M, Bats AS; Senticol 2 group
Eur J Cancer 2021 May;148:307-315. Epub 2021 Mar 24 doi: 10.1016/j.ejca.2021.02.009. PMID: 33773275
Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group.
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
Hormone Replacement Therapy in Cancer Survivors - Review of the Literature.
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article
Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference.
Nicolai N, Biasoni D, Catanzaro MA, Colecchia M, Trama A; RARECAREnet Working Group
Eur J Surg Oncol 2019 Jan;45(1):60-66. Epub 2018 Feb 14 doi: 10.1016/j.ejso.2018.02.006. PMID: 29526370

Diagnosis

Squamous Cell Carcinoma Arising in Breast Implant Capsules.
Goldberg MT, Llaneras J, Willson TD, Boyd JB, Venegas RJ, Dauphine C, Kalantari BN
Ann Plast Surg 2021 Mar 1;86(3):268-272. doi: 10.1097/SAP.0000000000002524. PMID: 32804719
Cutaneous metastases: A great imitator.
Jaros J, Hunt S, Mose E, Lai O, Tsoukas M
Clin Dermatol 2020 Mar-Apr;38(2):216-222. Epub 2019 Oct 25 doi: 10.1016/j.clindermatol.2019.10.004. PMID: 32513401
Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference.
Nicolai N, Biasoni D, Catanzaro MA, Colecchia M, Trama A; RARECAREnet Working Group
Eur J Surg Oncol 2019 Jan;45(1):60-66. Epub 2018 Feb 14 doi: 10.1016/j.ejso.2018.02.006. PMID: 29526370
Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study.
Cagney DN, Martin AM, Catalano PJ, Redig AJ, Lin NU, Lee EQ, Wen PY, Dunn IF, Bi WL, Weiss SE, Haas-Kogan DA, Alexander BM, Aizer AA
Neuro Oncol 2017 Oct 19;19(11):1511-1521. doi: 10.1093/neuonc/nox077. PMID: 28444227Free PMC Article
GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors.
Miettinen M, McCue PA, Sarlomo-Rikala M, Rys J, Czapiewski P, Wazny K, Langfort R, Waloszczyk P, Biernat W, Lasota J, Wang Z
Am J Surg Pathol 2014 Jan;38(1):13-22. doi: 10.1097/PAS.0b013e3182a0218f. PMID: 24145643Free PMC Article

Therapy

Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial.
Oaknin A, Gladieff L, Martínez-García J, Villacampa G, Takekuma M, De Giorgi U, Lindemann K, Woelber L, Colombo N, Duska L, Leary A, Godoy-Ortiz A, Nishio S, Angelergues A, Rubio MJ, Fariñas-Madrid L, Yamaguchi S, Lorusso D, Ray-Coquard I, Manso L, Joly F, Alarcón J, Follana P, Romero I, Lebreton C, Pérez-Fidalgo JA, Yunokawa M, Dahlstrand H, D'Hondt V, Randall LM; ENGOT-Cx10–GEICO 68-C–JGOG1084–GOG-3030 Investigators
Lancet 2024 Jan 6;403(10421):31-43. Epub 2023 Dec 1 doi: 10.1016/S0140-6736(23)02405-4. PMID: 38048793
Phase 2 study of osimertinib in combination with platinum and pemetrexed in patients with previously untreated EGFR-mutated advanced non-squamous non-small cell lung cancer: The OPAL Study.
Saito R, Sugawara S, Ko R, Azuma K, Morita R, Maemondo M, Oizumi S, Takahashi K, Kagamu H, Tsubata Y, Seike M, Kikuchi T, Okamoto I, Satoshi M, Asahina H, Tanaka K, Sugio K, Kobayashi K
Eur J Cancer 2023 May;185:83-93. Epub 2023 Mar 2 doi: 10.1016/j.ejca.2023.02.023. PMID: 36966696
Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group.
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
Hormone Replacement Therapy in Cancer Survivors - Review of the Literature.
Deli T, Orosz M, Jakab A
Pathol Oncol Res 2020 Jan;26(1):63-78. Epub 2019 Jan 8 doi: 10.1007/s12253-018-00569-x. PMID: 30617760Free PMC Article
Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study.
Cagney DN, Martin AM, Catalano PJ, Redig AJ, Lin NU, Lee EQ, Wen PY, Dunn IF, Bi WL, Weiss SE, Haas-Kogan DA, Alexander BM, Aizer AA
Neuro Oncol 2017 Oct 19;19(11):1511-1521. doi: 10.1093/neuonc/nox077. PMID: 28444227Free PMC Article

Prognosis

Sentinel lymph node biopsy and morbidity outcomes in early cervical cancer: Results of a multicentre randomised trial (SENTICOL-2).
Mathevet P, Lécuru F, Uzan C, Boutitie F, Magaud L, Guyon F, Querleu D, Fourchotte V, Baron M, Bats AS; Senticol 2 group
Eur J Cancer 2021 May;148:307-315. Epub 2021 Mar 24 doi: 10.1016/j.ejca.2021.02.009. PMID: 33773275
Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group.
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference.
Nicolai N, Biasoni D, Catanzaro MA, Colecchia M, Trama A; RARECAREnet Working Group
Eur J Surg Oncol 2019 Jan;45(1):60-66. Epub 2018 Feb 14 doi: 10.1016/j.ejso.2018.02.006. PMID: 29526370
Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study.
Cagney DN, Martin AM, Catalano PJ, Redig AJ, Lin NU, Lee EQ, Wen PY, Dunn IF, Bi WL, Weiss SE, Haas-Kogan DA, Alexander BM, Aizer AA
Neuro Oncol 2017 Oct 19;19(11):1511-1521. doi: 10.1093/neuonc/nox077. PMID: 28444227Free PMC Article
GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors.
Miettinen M, McCue PA, Sarlomo-Rikala M, Rys J, Czapiewski P, Wazny K, Langfort R, Waloszczyk P, Biernat W, Lasota J, Wang Z
Am J Surg Pathol 2014 Jan;38(1):13-22. doi: 10.1097/PAS.0b013e3182a0218f. PMID: 24145643Free PMC Article

Clinical prediction guides

Assessing PD-L1 Expression in Head and Neck Squamous Cell Carcinoma: Trials and Tribulations.
Bill R, Faquin WC, Pai SI
Head Neck Pathol 2023 Dec;17(4):969-975. Epub 2023 Nov 6 doi: 10.1007/s12105-023-01590-6. PMID: 37930471Free PMC Article
Preoperative MRI of breast squamous cell carcinoma: diagnostic value of distinguishing between two subtypes.
Chen S, Du Y, Hu Y, Ling R, Huang D, Xiang J, Liang Y, Wei X, Tang W, Guo Y
Clin Radiol 2022 Apr;77(4):e321-e328. Epub 2022 Jan 31 doi: 10.1016/j.crad.2021.12.018. PMID: 35093233
Sentinel lymph node biopsy and morbidity outcomes in early cervical cancer: Results of a multicentre randomised trial (SENTICOL-2).
Mathevet P, Lécuru F, Uzan C, Boutitie F, Magaud L, Guyon F, Querleu D, Fourchotte V, Baron M, Bats AS; Senticol 2 group
Eur J Cancer 2021 May;148:307-315. Epub 2021 Mar 24 doi: 10.1016/j.ejca.2021.02.009. PMID: 33773275
Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group.
Mosele F, Remon J, Mateo J, Westphalen CB, Barlesi F, Lolkema MP, Normanno N, Scarpa A, Robson M, Meric-Bernstam F, Wagle N, Stenzinger A, Bonastre J, Bayle A, Michiels S, Bièche I, Rouleau E, Jezdic S, Douillard JY, Reis-Filho JS, Dienstmann R, André F
Ann Oncol 2020 Nov;31(11):1491-1505. Epub 2020 Aug 24 doi: 10.1016/j.annonc.2020.07.014. PMID: 32853681
GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors.
Miettinen M, McCue PA, Sarlomo-Rikala M, Rys J, Czapiewski P, Wazny K, Langfort R, Waloszczyk P, Biernat W, Lasota J, Wang Z
Am J Surg Pathol 2014 Jan;38(1):13-22. doi: 10.1097/PAS.0b013e3182a0218f. PMID: 24145643Free PMC Article

Recent systematic reviews

Clinical impact of low-volume lymph node metastases in early-stage cervical cancer: A comprehensive meta-analysis.
Guani B, Mahiou K, Crestani A, Cibula D, Buda A, Gaillard T, Mathevet P, Kocian R, Sniadecki M, Wydra DG, Feki A, Paoletti X, Lecuru F, Balaya V
Gynecol Oncol 2022 Feb;164(2):446-454. Epub 2021 Dec 20 doi: 10.1016/j.ygyno.2021.12.015. PMID: 34949436
Deep inferior epigastric artery perforator free flap in head and neck reconstruction: A systematic review.
Mayo-Yáñez M, Rodríguez-Pérez E, Chiesa-Estomba CM, Calvo-Henríquez C, Rodríguez-Lorenzo A
J Plast Reconstr Aesthet Surg 2021 Apr;74(4):718-729. Epub 2020 Nov 20 doi: 10.1016/j.bjps.2020.11.008. PMID: 33334702
Computer-assisted diagnosis techniques (dermoscopy and spectroscopy-based) for diagnosing skin cancer in adults.
Ferrante di Ruffano L, Takwoingi Y, Dinnes J, Chuchu N, Bayliss SE, Davenport C, Matin RN, Godfrey K, O'Sullivan C, Gulati A, Chan SA, Durack A, O'Connell S, Gardiner MD, Bamber J, Deeks JJ, Williams HC; Cochrane Skin Cancer Diagnostic Test Accuracy Group
Cochrane Database Syst Rev 2018 Dec 4;12(12):CD013186. doi: 10.1002/14651858.CD013186. PMID: 30521691Free PMC Article
Vulvar, Perianal and Perineal Cancer After Hidradenitis Suppurativa: A Systematic Review and Pooled Analysis.
Makris GM, Poulakaki N, Papanota AM, Kotsifa E, Sergentanis TN, Psaltopoulou T
Dermatol Surg 2017 Jan;43(1):107-115. doi: 10.1097/DSS.0000000000000944. PMID: 27755170
Does the taking of biopsies affect the metastatic potential of tumours? A systematic review of reports on veterinary and human cases and animal models.
Klopfleisch R, Sperling C, Kershaw O, Gruber AD
Vet J 2011 Nov;190(2):e31-e42. Epub 2011 Jul 1 doi: 10.1016/j.tvjl.2011.04.010. PMID: 21723757

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