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Small intestinal mucosa-associated lymphoid tissue lymphoma

MedGen UID:
233452
•Concept ID:
C1336004
•
Neoplastic Process
Synonyms: MALT Lymphoma of Small Bowel; MALT lymphoma of small bowel; MALT Lymphoma of Small Intestine; MALT lymphoma of small intestine; MALT Lymphoma of the Small Bowel; MALT lymphoma of the small bowel; MALT Lymphoma of the Small Intestine; MALT lymphoma of the small intestine; MALToma of Small Bowel; MALToma of small bowel; MALToma of Small Intestine; MALToma of small intestine; MALToma of the Small Bowel; MALToma of the small bowel; MALToma of the Small Intestine; MALToma of the small intestine; Mucosa-Associated Lymphoid Tissue Lymphoma of Small Bowel; mucosa-associated lymphoid tissue lymphoma of small bowel; Mucosa-Associated Lymphoid Tissue Lymphoma of Small Intestine; mucosa-associated lymphoid tissue lymphoma of small intestine; Mucosa-Associated Lymphoid Tissue Lymphoma of the Small Bowel; mucosa-associated lymphoid tissue lymphoma of the small bowel; Mucosa-Associated Lymphoid Tissue Lymphoma of the Small Intestine; mucosa-associated lymphoid tissue lymphoma of the small intestine; Small Bowel MALT Lymphoma; small bowel MALT lymphoma; Small Bowel MALToma; small bowel MALToma; Small Bowel Mucosa-Associated Lymphoid Tissue Lymphoma; small bowel mucosa-associated lymphoid tissue lymphoma; Small Intestinal Mucosa-Associated Lymphoid Tissue Lymphoma; small intestinal mucosa-associated lymphoid tissue lymphoma; Small Intestine MALT Lymphoma; small intestine MALT lymphoma; Small Intestine MALToma; small intestine MALToma; Small Intestine Mucosa-Associated Lymphoid Tissue Lymphoma; small intestine mucosa-associated lymphoid tissue lymphoma
 
Monarch Initiative: MONDO:0006420

Definition

A mucosa-associated lymphoid tissue lymphoma (MALT) that arises from the small intestine. The morphologic characteristics are similar to those seen in gastric MALT lymphomas, with the exception of the lymphoepithelial lesions that are less prominent in the small intestine. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSmall intestinal mucosa-associated lymphoid tissue lymphoma

Professional guidelines

PubMed

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
Management of the marginal zone lymphomas.
Vannata B, Stathis A, Zucca E
Cancer Treat Res 2015;165:227-49. doi: 10.1007/978-3-319-13150-4_9. PMID: 25655612
Gastrointestinal lymphoma: recent advances in diagnosis and treatment.
Nakamura S, Matsumoto T
Digestion 2013;87(3):182-8. Epub 2013 Apr 27 doi: 10.1159/000350051. PMID: 23635497

Recent clinical studies

Etiology

B Cell Lymphomas of the GI Tract.
Small S, Barnea Slonim L, Williams C, Karmali R
Curr Gastroenterol Rep 2021 May 8;23(7):9. doi: 10.1007/s11894-021-00811-8. PMID: 33963950
Clinical course of duodenal mucosa-associated lymphoid tissue lymphoma: Comparison with gastric mucosa-associated lymphoid tissue lymphoma.
Na HK, Won SH, Ahn JY, Kim GH, Jung KW, Lee JH, Kim DH, Choi KD, Song HJ, Lee GH, Jung HY, Kim HJ
J Gastroenterol Hepatol 2021 Feb;36(2):406-412. Epub 2020 Jul 21 doi: 10.1111/jgh.15157. PMID: 32573049
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Primary gastrointestinal lymphomas.
Cooper DL, Doria R, Salloum E
Gastroenterologist 1996 Mar;4(1):54-64. PMID: 8689146
Gastrointestinal lymphoma.
Isaacson PG
Hum Pathol 1994 Oct;25(10):1020-9. doi: 10.1016/0046-8177(94)90060-4. PMID: 7927306

Diagnosis

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
B Cell Lymphomas of the GI Tract.
Small S, Barnea Slonim L, Williams C, Karmali R
Curr Gastroenterol Rep 2021 May 8;23(7):9. doi: 10.1007/s11894-021-00811-8. PMID: 33963950
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Duodenal-Type Follicular Lymphoma: A Clinicopathologic Review.
Marks E, Shi Y
Arch Pathol Lab Med 2018 Apr;142(4):542-547. doi: 10.5858/arpa.2016-0519-RS. PMID: 29565210
Marginal zone lymphoma.
Shaye OS, Levine AM
J Natl Compr Canc Netw 2006 Mar;4(3):311-8. doi: 10.6004/jnccn.2006.0026. PMID: 16507274

Therapy

Immunoproliferative Small Intestinal Disease in a Liver Transplant Recipient: A Case Report and Literature Review.
Orfanoudaki E, Iliadis A, Goulis I, Xylouri E, Voumvouraki A, Samonakis DN
Exp Clin Transplant 2021 Jun;19(6):620-623. doi: 10.6002/ect.2021.0015. PMID: 34085608
The spectrum of MALT lymphoma at different sites: biological and therapeutic relevance.
Zucca E, Bertoni F
Blood 2016 Apr 28;127(17):2082-92. Epub 2016 Mar 17 doi: 10.1182/blood-2015-12-624304. PMID: 26989205
Management of the marginal zone lymphomas.
Vannata B, Stathis A, Zucca E
Cancer Treat Res 2015;165:227-49. doi: 10.1007/978-3-319-13150-4_9. PMID: 25655612
Role of radiotherapy in the treatment of lymphomas of the gastrointestinal tract.
Aleman BM, Haas RL, van der Maazen RW
Best Pract Res Clin Gastroenterol 2010 Feb;24(1):27-34. doi: 10.1016/j.bpg.2009.12.002. PMID: 20206106
Lymphoma of the gastrointestinal tract.
Crump M, Gospodarowicz M, Shepherd FA
Semin Oncol 1999 Jun;26(3):324-37. PMID: 10375089

Prognosis

Primary Duodenal Mucosa-associated Lymphoid Tissue Lymphoma Treated with Radiation Therapy Alone.
Lee WJ, Ma KY, Oh HH, Choi YD, Joo YE
Korean J Gastroenterol 2023 Mar 25;81(3):129-132. doi: 10.4166/kjg.2022.128. PMID: 36960696
Synchronous duodenal mucosa-associated lymphoid tissue lymphoma and gastric cancer.
Yokota K, Namikawa T, Maeda M, Tanioka N, Iwabu J, Uemura S, Munekage M, Maeda H, Kitagawa H, Kobayashi M, Hanazaki K
Clin J Gastroenterol 2021 Feb;14(1):109-114. Epub 2020 Sep 21 doi: 10.1007/s12328-020-01241-1. PMID: 32959165
Clinical course of duodenal mucosa-associated lymphoid tissue lymphoma: Comparison with gastric mucosa-associated lymphoid tissue lymphoma.
Na HK, Won SH, Ahn JY, Kim GH, Jung KW, Lee JH, Kim DH, Choi KD, Song HJ, Lee GH, Jung HY, Kim HJ
J Gastroenterol Hepatol 2021 Feb;36(2):406-412. Epub 2020 Jul 21 doi: 10.1111/jgh.15157. PMID: 32573049
Duodenal-Type Follicular Lymphoma: A Clinicopathologic Review.
Marks E, Shi Y
Arch Pathol Lab Med 2018 Apr;142(4):542-547. doi: 10.5858/arpa.2016-0519-RS. PMID: 29565210
Gastrointestinal lymphoma.
Isaacson PG
Hum Pathol 1994 Oct;25(10):1020-9. doi: 10.1016/0046-8177(94)90060-4. PMID: 7927306

Clinical prediction guides

Clinicopathological characteristics of diffuse large B-cell lymphoma involving small and large intestines: an analysis of 126 patients.
Maeshima AM, Taniguchi H, Ito Y, Hatta S, Suzuki T, Yuda S, Makita S, Fukuhara S, Munakata W, Suzuki T, Maruyama D, Izutsu K
Int J Hematol 2019 Sep;110(3):340-346. Epub 2019 Jun 11 doi: 10.1007/s12185-019-02687-x. PMID: 31187439
Prognostic value of chromosomal translocations in small-bowel diffuse large B-cell lymphoma.
Ikegami K, Nakamura S, Esaki M, Yanai S, Hirahashi M, Oda Y, Takeshita M, Matsumoto T, Kitazono T
Histopathology 2016 Jan;68(2):199-209. Epub 2015 Jun 18 doi: 10.1111/his.12731. PMID: 25953462
Multiple Intestinal Lymphoma.
Mastalier B, Deaconescu V, Elaiah W, Drăghici C, Popp C, Zurac S, Balea M, Tevet M, Botezatu C
Rom J Intern Med 2015 Jan-Mar;53(1):73-8. doi: 10.1515/rjim-2015-0010. PMID: 26076564
Expression of PIK3CA and FOXP1 in gastric and intestinal non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue type.
Zhai L, Zhao Y, Ye S, Huang H, Tian Y, Wu Q, Lin H, Lin T
Tumour Biol 2011 Oct;32(5):913-20. Epub 2011 Jun 10 doi: 10.1007/s13277-011-0192-3. PMID: 21660567
Pathology of intestinal lymphomas.
Foss HD, Stein H
Recent Results Cancer Res 2000;156:33-41. doi: 10.1007/978-3-642-57054-4_5. PMID: 10802861

Recent systematic reviews

Treating chronic diarrhea: A systematic review on Immunoproliferative Small Intestinal Disease (IPSID).
Evangelista-Leite D, Affonso Madaloso B, Shouta Yamashita B, Enrico Aloise F, Polito Verdasca L, Lopes de Mello M, Murata Hayashi R, Zimberg Chehter E
PLoS One 2021;16(7):e0253695. Epub 2021 Jul 16 doi: 10.1371/journal.pone.0253695. PMID: 34270561Free PMC Article

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