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Non-Neoplastic Peripheral Nervous System Disorder

MedGen UID:
233777
•Concept ID:
C1335029
•
Disease or Syndrome
Synonym: Non-Neoplastic Peripheral Nervous System Disease

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-Neoplastic Peripheral Nervous System Disorder

Professional guidelines

PubMed

Special issues in the management of gliomas in children with neurofibromatosis 1.
Pollack IF, Mulvihill JJ
J Neurooncol 1996 May-Jun;28(2-3):257-68. doi: 10.1007/BF00250204. PMID: 8832467
Management of intracranial neoplasms in children with neurofibromatosis type 1 and 2. The Children's Cancer Study Group.
Cohen BH, Kaplan AM, Packer RJ
Pediatr Neurosurg 1990-1991;16(2):66-72. doi: 10.1159/000120510. PMID: 2132927

Recent clinical studies

Etiology

Neurofibromatosis type 1-associated optic pathway gliomas: pathogenesis and emerging treatments.
Amato A, Imbimbo BP, Falsini B
Eur Rev Med Pharmacol Sci 2023 Jun;27(12):5636-5653. doi: 10.26355/eurrev_202306_32804. PMID: 37401302
Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1.
Cimino PJ, Ketchum C, Turakulov R, Singh O, Abdullaev Z, Giannini C, Pytel P, Lopez GY, Colman H, Nasrallah MP, Santi M, Fernandes IL, Nirschl J, Dahiya S, Neill S, Solomon D, Perez E, Capper D, Mani H, Caccamo D, Ball M, Badruddoja M, Chkheidze R, Camelo-Piragua S, Fullmer J, Alexandrescu S, Yeaney G, Eberhart C, Martinez-Lage M, Chen J, Zach L, Kleinschmidt-DeMasters BK, Hefti M, Lopes MB, Nuechterlein N, Horbinski C, Rodriguez FJ, Quezado M, Pratt D, Aldape K
Acta Neuropathol 2023 Jan;145(1):71-82. Epub 2022 Oct 22 doi: 10.1007/s00401-022-02513-5. PMID: 36271929Free PMC Article
Percutaneous cryoanalgesia for pain palliation: Current status and future trends.
Filippiadis D, Efthymiou E, Tsochatzis A, Kelekis A, Prologo JD
Diagn Interv Imaging 2021 May;102(5):273-278. Epub 2020 Dec 3 doi: 10.1016/j.diii.2020.11.007. PMID: 33281081
An update on the central nervous system manifestations of neurofibromatosis type 1.
Nix JS, Blakeley J, Rodriguez FJ
Acta Neuropathol 2020 Apr;139(4):625-641. Epub 2019 Apr 8 doi: 10.1007/s00401-019-02002-2. PMID: 30963251Free PMC Article
Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms.
Longo JF, Weber SM, Turner-Ivey BP, Carroll SL
Adv Anat Pathol 2018 Sep;25(5):353-368. doi: 10.1097/PAP.0000000000000197. PMID: 29762158Free PMC Article

Diagnosis

Neurofibromatosis type 1-associated optic pathway gliomas: pathogenesis and emerging treatments.
Amato A, Imbimbo BP, Falsini B
Eur Rev Med Pharmacol Sci 2023 Jun;27(12):5636-5653. doi: 10.26355/eurrev_202306_32804. PMID: 37401302
Ultrasound and MR imaging of peripheral nerve tumors: the state of the art.
Lefebvre G, Le Corroller T
Skeletal Radiol 2023 Mar;52(3):405-419. Epub 2022 Jun 17 doi: 10.1007/s00256-022-04087-5. PMID: 35713690
An update on the central nervous system manifestations of neurofibromatosis type 1.
Nix JS, Blakeley J, Rodriguez FJ
Acta Neuropathol 2020 Apr;139(4):625-641. Epub 2019 Apr 8 doi: 10.1007/s00401-019-02002-2. PMID: 30963251Free PMC Article
Benign peripheral nerve tumors.
Kokkalis ZT, Stavropoulos NA, Mavrogenis AF, Panagopoulos A, Soucacos PN
Injury 2019 Dec;50 Suppl 5:S77-S83. Epub 2019 Oct 23 doi: 10.1016/j.injury.2019.10.054. PMID: 31708092
Cauda equina syndrome.
Orendácová J, Cízková D, Kafka J, Lukácová N, Marsala M, Sulla I, Marsala J, Katsube N
Prog Neurobiol 2001 Aug;64(6):613-37. doi: 10.1016/s0301-0082(00)00065-4. PMID: 11311464

Therapy

Neurofibromatosis type 1-associated optic pathway gliomas: pathogenesis and emerging treatments.
Amato A, Imbimbo BP, Falsini B
Eur Rev Med Pharmacol Sci 2023 Jun;27(12):5636-5653. doi: 10.26355/eurrev_202306_32804. PMID: 37401302
Percutaneous cryoanalgesia for pain palliation: Current status and future trends.
Filippiadis D, Efthymiou E, Tsochatzis A, Kelekis A, Prologo JD
Diagn Interv Imaging 2021 May;102(5):273-278. Epub 2020 Dec 3 doi: 10.1016/j.diii.2020.11.007. PMID: 33281081
Multivacuolated mucin-filled cells: a unique cell characteristic of plexiform neurofibroma. A report of 11 cases.
Michal M, Kazakov DV, Hadravský L, Michalová K, Rychlý B, Michal M
Hum Pathol 2017 Feb;60:167-173. Epub 2016 Nov 2 doi: 10.1016/j.humpath.2016.10.010. PMID: 27816720
Disarticulation resections of the mandible: a prospective review of 16 cases.
Carlson ER
J Oral Maxillofac Surg 2002 Feb;60(2):176-81. doi: 10.1053/joms.2002.29815. PMID: 11815917
Adjunctive use of endoscopy during posterior fossa surgery to treat cranial neuropathies.
King WA, Wackym PA, Sen C, Meyer GA, Shiau J, Deutsch H
Neurosurgery 2001 Jul;49(1):108-15; discussion 115-6. doi: 10.1097/00006123-200107000-00017. PMID: 11440431

Prognosis

Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas.
Amani V, Riemondy KA, Fu R, Griesinger AM, Grimaldo E, De Sousa GR, Gilani A, Hemenway M, Foreman NK, Donson AM, Willard N
Acta Neuropathol Commun 2023 Sep 28;11(1):158. doi: 10.1186/s40478-023-01639-1. PMID: 37770931Free PMC Article
Baseline serum/cerebrospinal fluid ratio of carcinoembryonic antigen and carbohydrate antigen series biomarkers in non-neoplastic diseases: a cross-sectional study on 224 patients.
Zhang Y, Ban R, Shi Q, Tian C
Clin Biochem 2019 Jan;63:135-138. Epub 2018 Nov 4 doi: 10.1016/j.clinbiochem.2018.11.003. PMID: 30403967
Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms.
Longo JF, Weber SM, Turner-Ivey BP, Carroll SL
Adv Anat Pathol 2018 Sep;25(5):353-368. doi: 10.1097/PAP.0000000000000197. PMID: 29762158Free PMC Article
Inhibin-A immunoreactivity in nervous system lesions.
Gurses I, Scheithauer BW
Appl Immunohistochem Mol Morphol 2012 May;20(3):277-84. doi: 10.1097/PAI.0b013e31823e5ba8. PMID: 22505009
Non-neoplastic brain abnormalities on MRI in children and adolescents with neurofibromatosis type 1.
Raininko R, Thelin L, Eeg-Olofsson O
Neuropediatrics 2001 Oct;32(5):225-30. doi: 10.1055/s-2001-19115. PMID: 11748492

Clinical prediction guides

Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas.
Amani V, Riemondy KA, Fu R, Griesinger AM, Grimaldo E, De Sousa GR, Gilani A, Hemenway M, Foreman NK, Donson AM, Willard N
Acta Neuropathol Commun 2023 Sep 28;11(1):158. doi: 10.1186/s40478-023-01639-1. PMID: 37770931Free PMC Article
Hyperplasia of Arachnoid Trabecular Cells: A Hitherto Undescribed Lesion Observed in the Setting of Neurofibromatosis Type 1.
Maehara T, Yamazaki A, Kawabata-Iwakawa R, Fukuoka K, Akazawa A, Okura N, Nishiyama M, Nassiri F, Wang JZ, Zadeh G, Kikuta K, Oka H, Hirato J, Yokoo H, Nobusawa S
Am J Surg Pathol 2023 Jul 1;47(7):819-825. Epub 2023 May 25 doi: 10.1097/PAS.0000000000002056. PMID: 37226836
TFG::MET-rearranged soft tissue tumor: A rare infantile neoplasm with a distinct low-grade triphasic morphology.
Michal M, Ud Din N, Švajdler M, Klubíčková N, Ptáková N, Hájková V, Michal M, Agaimy A
Genes Chromosomes Cancer 2023 May;62(5):290-296. Epub 2022 Dec 13 doi: 10.1002/gcc.23111. PMID: 36464850
Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms.
Longo JF, Weber SM, Turner-Ivey BP, Carroll SL
Adv Anat Pathol 2018 Sep;25(5):353-368. doi: 10.1097/PAP.0000000000000197. PMID: 29762158Free PMC Article
Inhibin-A immunoreactivity in nervous system lesions.
Gurses I, Scheithauer BW
Appl Immunohistochem Mol Morphol 2012 May;20(3):277-84. doi: 10.1097/PAI.0b013e31823e5ba8. PMID: 22505009

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