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Microcystic meningioma

MedGen UID:
234616
•Concept ID:
C1384408
•
Neoplastic Process
Synonyms: Meningioma, Microcystic; Meningiomas, Microcystic; Microcystic Meningioma; Microcystic Meningiomas
SNOMED CT: Microcystic meningioma (253084001)
 
Monarch Initiative: MONDO:0003058

Definition

A WHO grade I meningioma characterized by the presence of intercellular microcystic spaces that contain mucinous fluid. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMicrocystic meningioma

Professional guidelines

PubMed

EANO guideline on the diagnosis and management of meningiomas.
Goldbrunner R, Stavrinou P, Jenkinson MD, Sahm F, Mawrin C, Weber DC, Preusser M, Minniti G, Lund-Johansen M, Lefranc F, Houdart E, Sallabanda K, Le Rhun E, Nieuwenhuizen D, Tabatabai G, Soffietti R, Weller M
Neuro Oncol 2021 Nov 2;23(11):1821-1834. doi: 10.1093/neuonc/noab150. PMID: 34181733Free PMC Article
Meningioma: not always a benign tumor. A review of advances in the treatment of meningiomas.
Maggio I, Franceschi E, Tosoni A, Nunno VD, Gatto L, Lodi R, Brandes AA
CNS Oncol 2021 Jun 1;10(2):CNS72. Epub 2021 May 21 doi: 10.2217/cns-2021-0003. PMID: 34015955Free PMC Article
Current treatment options for meningioma.
Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

Recent clinical studies

Etiology

Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.
Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110
Comparative analysis of magnetic resonance imaging and pathological findings of microcystic meningioma and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumors.
Zhang J, Sun Q, Zhang G, Cao Y, Zhou J
Acta Neurol Belg 2021 Dec;121(6):1607-1613. Epub 2020 Jul 15 doi: 10.1007/s13760-020-01436-w. PMID: 32671692
Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.
Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968
Characteristic features and proposed classification in 69 cases of intracranial microcystic meningiomas.
Lin Z, Zhao M, Li X, Wang J, Qiu P, Lan F, Guan C, Liao D, Shen D, Lu J, Que S, Jiang Z
Neurosurg Rev 2019 Jun;42(2):443-453. Epub 2018 May 2 doi: 10.1007/s10143-018-0982-9. PMID: 29721630
Pediatric microcystic meningioma: a clinical, histological, and radiographic case-based review.
Manwaring J, Ahmadian A, Stapleton S, Gonzalez-Gomez I, Rodriguez L, Carey C, Tuite GF
Childs Nerv Syst 2013 Mar;29(3):361-5. Epub 2012 Dec 19 doi: 10.1007/s00381-012-1991-6. PMID: 23250249

Diagnosis

Distinct clinical outcome of microcystic meningioma as a WHO grade 1 meningioma subtype.
Ren L, Hua L, Bao Z, Deng J, Wang D, Chen J, Chen H, Juratli TA, Wakimoto H, Gong Y
J Neurooncol 2023 Jan;161(2):193-202. Epub 2022 May 25 doi: 10.1007/s11060-022-04034-3. PMID: 35612696
Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.
Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110
Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.
Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968
Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature.
Velázquez Vega JE, Rosenberg AE
Am J Surg Pathol 2015 Apr;39(4):505-11. doi: 10.1097/PAS.0000000000000347. PMID: 25517950
Intraosseous microcystic meningioma.
Okamoto S, Hisaoka M, Aoki T, Kadoya C, Kobanawa S, Hashimoto H
Skeletal Radiol 2000 Jun;29(6):354-7. doi: 10.1007/s002560000217. PMID: 10929419

Therapy

Loss of SMARCE1 expression is a specific diagnostic marker of clear cell meningioma: a comprehensive immunophenotypical and molecular analysis.
Tauziede-Espariat A, Parfait B, Besnard A, Lacombe J, Pallud J, Tazi S, Puget S, Lot G, Terris B, Cohen J, Vidaud M, Figarella-Branger D, Monnien F, Polivka M, Adle-Biassette H, Varlet P
Brain Pathol 2018 Jul;28(4):466-474. Epub 2017 Jun 12 doi: 10.1111/bpa.12524. PMID: 28474749Free PMC Article
Microcystic meningioma: importance of obvious hypointensity on T1-weighted magnetic resonance images.
Chen CJ, Tseng YC, Hsu HL, Jung SM
J Comput Assist Tomogr 2008 Jan-Feb;32(1):130-4. doi: 10.1097/RCT.0b013e318064f127. PMID: 18303301
Microcystic meningioma: clinicopathological features of 6 cases.
Nishio S, Takeshita I, Morioka T, Fukui M
Neurol Res 1994 Aug;16(4):251-6. doi: 10.1080/01616412.1994.11740236. PMID: 7984255

Prognosis

Distinct clinical outcome of microcystic meningioma as a WHO grade 1 meningioma subtype.
Ren L, Hua L, Bao Z, Deng J, Wang D, Chen J, Chen H, Juratli TA, Wakimoto H, Gong Y
J Neurooncol 2023 Jan;161(2):193-202. Epub 2022 May 25 doi: 10.1007/s11060-022-04034-3. PMID: 35612696
Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.
Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110
Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.
Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968
Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature.
Velázquez Vega JE, Rosenberg AE
Am J Surg Pathol 2015 Apr;39(4):505-11. doi: 10.1097/PAS.0000000000000347. PMID: 25517950
Pediatric microcystic meningioma: a clinical, histological, and radiographic case-based review.
Manwaring J, Ahmadian A, Stapleton S, Gonzalez-Gomez I, Rodriguez L, Carey C, Tuite GF
Childs Nerv Syst 2013 Mar;29(3):361-5. Epub 2012 Dec 19 doi: 10.1007/s00381-012-1991-6. PMID: 23250249

Clinical prediction guides

Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.
Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110
Comparative analysis of magnetic resonance imaging and pathological findings of microcystic meningioma and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumors.
Zhang J, Sun Q, Zhang G, Cao Y, Zhou J
Acta Neurol Belg 2021 Dec;121(6):1607-1613. Epub 2020 Jul 15 doi: 10.1007/s13760-020-01436-w. PMID: 32671692
Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.
Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968
Characteristic features and proposed classification in 69 cases of intracranial microcystic meningiomas.
Lin Z, Zhao M, Li X, Wang J, Qiu P, Lan F, Guan C, Liao D, Shen D, Lu J, Que S, Jiang Z
Neurosurg Rev 2019 Jun;42(2):443-453. Epub 2018 May 2 doi: 10.1007/s10143-018-0982-9. PMID: 29721630
Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature.
Velázquez Vega JE, Rosenberg AE
Am J Surg Pathol 2015 Apr;39(4):505-11. doi: 10.1097/PAS.0000000000000347. PMID: 25517950

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