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Non-Hereditary Clear Cell Renal Cell Carcinoma

MedGen UID:
235372
Concept ID:
C1334978
Neoplastic Process
Synonyms: Non-Hereditary Conventional (Clear Cell) Renal Cell Carcinoma; Sporadic Clear Cell Renal Cell Carcinoma; Sporadic Conventional (Clear Cell) Renal Cell Carcinoma

Definition

The most common type of renal cell carcinoma, characterized by a loss of genetic material of the short arm of chromosome 3. The most common symptom at the time of diagnosis is hematuria. The tumor has a golden-yellow color because of the abundance of intracytoplasmic lipid. This is a clinically aggressive type of renal cell carcinoma. The tumor usually metastasizes to unusual sites and late metastasis is common. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-Hereditary Clear Cell Renal Cell Carcinoma

Recent clinical studies

Etiology

Fan B, Wang W, Zhang X, Sun M, Wang X, Chen Z, Liu W, Wang Q, Yu N, Li X
BMC Cancer 2019 Jun 3;19(1):534. doi: 10.1186/s12885-019-5736-8. PMID: 31159774Free PMC Article
Grimaldi G, Reuter V, Russo P
Ann Surg Oncol 1998 Sep;5(6):548-52. doi: 10.1007/BF02303649. PMID: 9754765
Knudson AG Jr
Princess Takamatsu Symp 1989;20:15-29. PMID: 2577335

Diagnosis

Corral de la Calle MÁ, Encinas de la Iglesia J, Fernández Pérez GC, Fraino A, Repollés Cobaleda M
Radiologia (Engl Ed) 2024 Mar-Apr;66(2):132-154. Epub 2024 Mar 23 doi: 10.1016/j.rxeng.2024.03.001. PMID: 38614530
Fan B, Wang W, Zhang X, Sun M, Wang X, Chen Z, Liu W, Wang Q, Yu N, Li X
BMC Cancer 2019 Jun 3;19(1):534. doi: 10.1186/s12885-019-5736-8. PMID: 31159774Free PMC Article
Simms RJ, Ong AC
Nephrol Dial Transplant 2014 Sep;29 Suppl 4(Suppl 4):iv106-12. doi: 10.1093/ndt/gfu106. PMID: 25165175Free PMC Article

Prognosis

Fan B, Wang W, Zhang X, Sun M, Wang X, Chen Z, Liu W, Wang Q, Yu N, Li X
BMC Cancer 2019 Jun 3;19(1):534. doi: 10.1186/s12885-019-5736-8. PMID: 31159774Free PMC Article
Grimaldi G, Reuter V, Russo P
Ann Surg Oncol 1998 Sep;5(6):548-52. doi: 10.1007/BF02303649. PMID: 9754765

Clinical prediction guides

Fan B, Wang W, Zhang X, Sun M, Wang X, Chen Z, Liu W, Wang Q, Yu N, Li X
BMC Cancer 2019 Jun 3;19(1):534. doi: 10.1186/s12885-019-5736-8. PMID: 31159774Free PMC Article

Supplemental Content

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