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Functional cyst of ovary

MedGen UID:
256156
Concept ID:
C1142385
Anatomical Abnormality
Synonyms: Functional Cyst of Ovary; Functional Cyst of the Ovary; Functional ovarian cyst; Functional Ovarian Cyst
SNOMED CT: Functional ovarian cyst (116341001); Functional cyst of ovary (116341001)

Definition

A benign ovarian cyst that develops and regresses during the menstrual cycle as part of normal ovarian function. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFunctional cyst of ovary

Professional guidelines

PubMed

Teede HJ, Tay CT, Laven JJE, Dokras A, Moran LJ, Piltonen TT, Costello MF, Boivin J, Redman LM, Boyle JA, Norman RJ, Mousa A, Joham AE
J Clin Endocrinol Metab 2023 Sep 18;108(10):2447-2469. doi: 10.1210/clinem/dgad463. PMID: 37580314Free PMC Article
Shahid R, Iahtisham-Ul-Haq, Mahnoor, Awan KA, Iqbal MJ, Munir H, Saeed I
J Food Biochem 2022 Jul;46(7):e14117. Epub 2022 Feb 24 doi: 10.1111/jfbc.14117. PMID: 35199348
Sadeghi HM, Adeli I, Calina D, Docea AO, Mousavi T, Daniali M, Nikfar S, Tsatsakis A, Abdollahi M
Int J Mol Sci 2022 Jan 6;23(2) doi: 10.3390/ijms23020583. PMID: 35054768Free PMC Article

Recent clinical studies

Etiology

Tzur T, Tzur Y, Baruch S, Smorgick N, Melcer Y
Isr Med Assoc J 2022 Jan;24(1):15-19. PMID: 35077040
Dasgupta R, Renaud E, Goldin AB, Baird R, Cameron DB, Arnold MA, Diefenbach KA, Gosain A, Grabowski J, Guner YS, Jancelewicz T, Kawaguchi A, Lal DR, Oyetunji TA, Ricca RL, Shelton J, Somme S, Williams RF, Downard CD
J Pediatr Surg 2018 Jul;53(7):1387-1391. Epub 2017 Nov 16 doi: 10.1016/j.jpedsurg.2017.10.053. PMID: 29153467
Alammari R, Lightfoot M, Hur HC
J Minim Invasive Gynecol 2017 Feb;24(2):247-257. Epub 2017 Jan 9 doi: 10.1016/j.jmig.2016.12.010. PMID: 28089684
Muzii L, Di Tucci C, Di Feliciantonio M, Galati G, Verrelli L, Donato VD, Marchetti C, Panici PB
Semin Reprod Med 2017 Jan;35(1):25-30. Epub 2016 Dec 7 doi: 10.1055/s-0036-1597126. PMID: 27926971
Bottomley C, Bourne T
Best Pract Res Clin Obstet Gynaecol 2009 Oct;23(5):711-24. Epub 2009 Mar 18 doi: 10.1016/j.bpobgyn.2009.02.001. PMID: 19299205

Diagnosis

Munro MG, Balen AH, Cho S, Critchley HOD, Díaz I, Ferriani R, Henry L, Edgar Mocanu, van der Spuy ZM; FIGO Committee on Menstrual Disorders and Related Health Impacts, and FIGO Committee on Reproductive Medicine, Endocrinology, and Infertility
Fertil Steril 2022 Oct;118(4):768-786. Epub 2022 Aug 19 doi: 10.1016/j.fertnstert.2022.07.009. PMID: 35995633
Tan Y, Flynn WF, Sivajothi S, Luo D, Bozal SB, Davé M, Luciano AA, Robson P, Luciano DE, Courtois ET
Nat Cell Biol 2022 Aug;24(8):1306-1318. Epub 2022 Jul 21 doi: 10.1038/s41556-022-00961-5. PMID: 35864314Free PMC Article
Society for Maternal-Fetal Medicine (SMFM), Cheng Y
Am J Obstet Gynecol 2021 Nov;225(5):B23-B25. Epub 2021 Sep 8 doi: 10.1016/j.ajog.2021.06.042. PMID: 34507793
Muzii L, Di Tucci C, Di Feliciantonio M, Galati G, Verrelli L, Donato VD, Marchetti C, Panici PB
Semin Reprod Med 2017 Jan;35(1):25-30. Epub 2016 Dec 7 doi: 10.1055/s-0036-1597126. PMID: 27926971
Bottomley C, Bourne T
Best Pract Res Clin Obstet Gynaecol 2009 Oct;23(5):711-24. Epub 2009 Mar 18 doi: 10.1016/j.bpobgyn.2009.02.001. PMID: 19299205

Therapy

Jaripur M, Ghasemi-Tehrani H, Askari G, Gholizadeh-Moghaddam M, Clark CCT, Rouhani MH
Reprod Biol Endocrinol 2022 Aug 2;20(1):110. doi: 10.1186/s12958-022-00982-7. PMID: 35918728Free PMC Article
Dos Santos IK, Ashe MC, Cobucci RN, Soares GM, de Oliveira Maranhão TM, Dantas PMS
Medicine (Baltimore) 2020 Apr;99(16):e19644. doi: 10.1097/MD.0000000000019644. PMID: 32311937Free PMC Article
Kite C, Lahart IM, Afzal I, Broom DR, Randeva H, Kyrou I, Brown JE
Syst Rev 2019 Feb 12;8(1):51. doi: 10.1186/s13643-019-0962-3. PMID: 30755271Free PMC Article
Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group
Fertil Steril 2004 Jan;81(1):19-25. doi: 10.1016/j.fertnstert.2003.10.004. PMID: 14711538
Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group
Hum Reprod 2004 Jan;19(1):41-7. doi: 10.1093/humrep/deh098. PMID: 14688154

Prognosis

Yang B, Li X, Zhang W, Fan J, Zhou Y, Li W, Yin J, Yang X, Guo E, Li X, Fu Y, Liu S, Hu D, Qin X, Dou Y, Xiao R, Lu F, Wang Z, Qin T, Wang W, Zhang Q, Li S, Ma D, Mills GB, Chen G, Sun C
Cell Rep Med 2022 Dec 20;3(12):100856. doi: 10.1016/j.xcrm.2022.100856. PMID: 36543113Free PMC Article
Pkhaladze L, Russo M, Unfer V, Nordio M, Basciani S, Khomasuridze A
Eur Rev Med Pharmacol Sci 2021 Dec;25(23):7476-7485. doi: 10.26355/eurrev_202112_27447. PMID: 34919250
Kumariya S, Ubba V, Jha RK, Gayen JR
Autophagy 2021 Oct;17(10):2706-2733. Epub 2021 Jun 23 doi: 10.1080/15548627.2021.1938914. PMID: 34161185Free PMC Article
Stener-Victorin E, Padmanabhan V, Walters KA, Campbell RE, Benrick A, Giacobini P, Dumesic DA, Abbott DH
Endocr Rev 2020 Jul 1;41(4) doi: 10.1210/endrev/bnaa010. PMID: 32310267Free PMC Article
Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R
Fertil Steril 2016 Jul;106(1):6-15. Epub 2016 May 24 doi: 10.1016/j.fertnstert.2016.05.003. PMID: 27233760

Clinical prediction guides

Throwba H PK, Unnikrishnan L, Pangath M, Vasudevan K, Jayaraman S, Li M, Iyaswamy A, Palaniyandi K, Gnanasampanthapandian D
Crit Rev Oncol Hematol 2022 Dec;180:103852. Epub 2022 Oct 23 doi: 10.1016/j.critrevonc.2022.103852. PMID: 36283585
Kumariya S, Ubba V, Jha RK, Gayen JR
Autophagy 2021 Oct;17(10):2706-2733. Epub 2021 Jun 23 doi: 10.1080/15548627.2021.1938914. PMID: 34161185Free PMC Article
Stener-Victorin E, Padmanabhan V, Walters KA, Campbell RE, Benrick A, Giacobini P, Dumesic DA, Abbott DH
Endocr Rev 2020 Jul 1;41(4) doi: 10.1210/endrev/bnaa010. PMID: 32310267Free PMC Article
Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R
Fertil Steril 2016 Jul;106(1):6-15. Epub 2016 May 24 doi: 10.1016/j.fertnstert.2016.05.003. PMID: 27233760
Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R
Nat Rev Endocrinol 2011 Apr;7(4):219-31. Epub 2011 Jan 25 doi: 10.1038/nrendo.2010.217. PMID: 21263450

Recent systematic reviews

Greff D, Juhász AE, Váncsa S, Váradi A, Sipos Z, Szinte J, Park S, Hegyi P, Nyirády P, Ács N, Várbíró S, Horváth EM
Reprod Biol Endocrinol 2023 Jan 26;21(1):10. doi: 10.1186/s12958-023-01055-z. PMID: 36703143Free PMC Article
Gu Y, Zhou G, Zhou F, Wu Q, Ma C, Zhang Y, Ding J, Hua K
Front Endocrinol (Lausanne) 2022;13:808898. Epub 2022 Apr 13 doi: 10.3389/fendo.2022.808898. PMID: 35498415Free PMC Article
Sanchez-Garrido MA, Tena-Sempere M
Mol Metab 2020 May;35:100937. Epub 2020 Feb 5 doi: 10.1016/j.molmet.2020.01.001. PMID: 32244180Free PMC Article
Kite C, Lahart IM, Afzal I, Broom DR, Randeva H, Kyrou I, Brown JE
Syst Rev 2019 Feb 12;8(1):51. doi: 10.1186/s13643-019-0962-3. PMID: 30755271Free PMC Article
Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF; Task Force on the Phenotype of the Polycystic Ovary Syndrome of The Androgen Excess and PCOS Society
Fertil Steril 2009 Feb;91(2):456-88. Epub 2008 Oct 23 doi: 10.1016/j.fertnstert.2008.06.035. PMID: 18950759

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