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Retiform hemangioendothelioma

MedGen UID:
266274
Concept ID:
C1304512
Neoplastic Process
Synonyms: Hobnail Hemangioendothelioma; hobnail hemangioendothelioma; Retiform Hemangioendothelioma; retiform hemangioendothelioma
SNOMED CT: Retiform hemangioendothelioma (403982005); Retiform hemangioendothelioma (703659003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0018713
Orphanet: ORPHA458763

Definition

A rare vascular tumor characterized by a slowly growing lesion with predominant involvement of the skin and subcutaneous tissue of the distal extremities. Distinctive arborizing blood vessels lined by endothelial cells with characteristic hobnail morphology are a typical feature. Local recurrences are frequent unless wide local excision is performed, while metastasis is rare. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRetiform hemangioendothelioma

Recent clinical studies

Etiology

Folpe AL
Hum Pathol 2024 May;147:114-128. Epub 2024 Feb 13 doi: 10.1016/j.humpath.2024.01.014. PMID: 38360216
Zhang X, Wang S, Jin M
Heart Surg Forum 2022 Apr 22;25(2):E284-E287. doi: 10.1532/hsf.4587. PMID: 35486043
Díaz-Flores L, Gutiérrez R, García-Suárez MP, Sáez FJ, Gutiérrez E, Valladares F, Carrasco JL, Díaz-Flores L Jr, Madrid JF
Histol Histopathol 2017 Dec;32(12):1239-1279. Epub 2017 Aug 1 doi: 10.14670/HH-11-923. PMID: 28762232
Requena L, Luis Díaz J, Manzarbeitia F, Carrillo R, Fernández-Herrera J, Kutzner H
J Cutan Pathol 2008 Feb;35(2):225-30. doi: 10.1111/j.1600-0560.2007.00781.x. PMID: 18190450
Fletcher CD
Verh Dtsch Ges Pathol 1998;82:33-46. PMID: 10095415

Diagnosis

Folpe AL
Hum Pathol 2024 May;147:114-128. Epub 2024 Feb 13 doi: 10.1016/j.humpath.2024.01.014. PMID: 38360216
Chundriger Q, Tariq MU, Rahim S, Abdul-Ghafar J, Din NU
J Med Case Rep 2021 Feb 17;15(1):69. doi: 10.1186/s13256-021-02671-2. PMID: 33593408Free PMC Article
Mondal A, Das M, Chatterjee U, Datta C
Indian J Pathol Microbiol 2020 Jan-Mar;63(1):122-124. doi: 10.4103/IJPM.IJPM_237_19. PMID: 32031140
Al-Faky YH, Al-Mosallam AR, Al-Rikabi AC, Al-Sohaibani MO
Indian J Ophthalmol 2014 Apr;62(4):491-3. doi: 10.4103/0301-4738.126995. PMID: 24817752Free PMC Article
El Darouti M, Marzouk SA, Sobhi RM, Bassiouni DA
Int J Dermatol 2000 May;39(5):365-8. doi: 10.1046/j.1365-4362.2000.00841-1.x. PMID: 10849129

Therapy

Nobeyama Y, Ishiuji Y, Nakagawa H
Int J Dermatol 2016 Feb;55(2):238-43. Epub 2015 Aug 12 doi: 10.1111/ijd.12908. PMID: 26267121
Albertini AF, Brousse N, Bodemer C, Calonje E, Fraitag S
Am J Dermatopathol 2011 Oct;33(7):e84-7. doi: 10.1097/DAD.0b013e31821b0a9f. PMID: 21915027

Prognosis

Dermawan JK, Westra WH, Antonescu CR
Genes Chromosomes Cancer 2022 Apr;61(4):187-193. Epub 2021 Dec 11 doi: 10.1002/gcc.23017. PMID: 34862698Free PMC Article
Zhang M, Yin X, Yao W, Liu N, Yue Y
J Int Med Res 2021 Aug;49(8):3000605211027783. doi: 10.1177/03000605211027783. PMID: 34340581Free PMC Article
Al-Faky YH, Al-Mosallam AR, Al-Rikabi AC, Al-Sohaibani MO
Indian J Ophthalmol 2014 Apr;62(4):491-3. doi: 10.4103/0301-4738.126995. PMID: 24817752Free PMC Article
Ioannidou D, Panayiotides J, Krasagakis K, Stefanidou M, Manios A, Tosca A
Int J Dermatol 2006 Jan;45(1):53-5. doi: 10.1111/j.1365-4632.2004.02341.x. PMID: 16426378
Requena L, Sangueza OP
J Am Acad Dermatol 1998 Feb;38(2 Pt 1):143-75; quiz 176-8. doi: 10.1016/s0190-9622(98)70237-3. PMID: 9486670

Clinical prediction guides

Gündoğan BD, Çıtak EÇ, Sağcan F, Esen K, Yıldız A, Arpacı RB
Turk J Pediatr 2020;62(5):843-850. doi: 10.24953/turkjped.2020.05.018. PMID: 33108089
Díaz-Flores L, Gutiérrez R, García-Suárez MP, Sáez FJ, Gutiérrez E, Valladares F, Carrasco JL, Díaz-Flores L Jr, Madrid JF
Histol Histopathol 2017 Dec;32(12):1239-1279. Epub 2017 Aug 1 doi: 10.14670/HH-11-923. PMID: 28762232
Miettinen M, Wang ZF
Am J Surg Pathol 2012 Mar;36(3):351-9. doi: 10.1097/PAS.0b013e318236c312. PMID: 22067331Free PMC Article
Guillou L, Calonje E, Speight P, Rosai J, Fletcher CD
Am J Surg Pathol 1999 Jan;23(1):97-105. doi: 10.1097/00000478-199901000-00011. PMID: 9888709

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