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Grade 1 Meningioma

MedGen UID:
268144
•Concept ID:
C1512260
•
Neoplastic Process
Synonyms: Grade I Meningioma; WHO Grade 1 Meningioma; WHO Grade I Meningioma

Definition

A benign meningioma which may recur in approximately 7-20% of the cases. This category includes the angiomatous meningioma, fibrous meningioma, lymphoplasmacyte-rich meningioma, meningothelial meningioma, metaplastic meningioma, microcystic meningioma, psammomatous meningioma, secretory meningioma, and transitional meningioma. [from NCI]

Professional guidelines

PubMed

Epigenetic and genomic profiling of chordoid meningioma: implications for clinical management.
Daoud EV, Zhu K, Mickey B, Mohamed H, Wen M, Delorenzo M, Tran I, Serrano J, Hatanpaa KJ, Raisanen JM, Snuderl M, Cai C
Acta Neuropathol Commun 2022 Apr 19;10(1):56. doi: 10.1186/s40478-022-01362-3. PMID: 35440040Free PMC Article
Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: International Stereotactic Radiosurgery Society Systematic Review, Meta-Analysis and Practice Guideline.
Marchetti M, Sahgal A, De Salles AAF, Levivier M, Ma L, Paddick I, Pollock BE, Regis J, Sheehan J, Suh JH, Yomo S, Fariselli L
Neurosurgery 2020 Oct 15;87(5):879-890. doi: 10.1093/neuros/nyaa169. PMID: 32463867Free PMC Article
MR-guided laser interstitial thermal therapy in the treatment of recurrent intracranial meningiomas.
Rammo R, Scarpace L, Nagaraja T, Lee I
Lasers Surg Med 2019 Mar;51(3):245-250. Epub 2018 Dec 28 doi: 10.1002/lsm.23045. PMID: 30592538

Recent clinical studies

Etiology

A single-center experience with linear accelerator-based stereotactic radiotherapy for meningiomas: hypofractionation and radiosurgery.
Gawish A, Abdulayev N, El-Arayed S, Röllich B, Ochel HJ, Brunner TB
J Cancer Res Clin Oncol 2023 Jan;149(1):103-109. Epub 2022 Oct 28 doi: 10.1007/s00432-022-04450-y. PMID: 36307558Free PMC Article
Low-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539.
Rogers CL, Pugh SL, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Barani IJ, Braunstein S, Bovi JA, de Groot JF, Whitton AC, Lindhorst SM, Deb N, Shrieve DC, Shu HK, Bloom B, Machtay M, Mishra MV, Robinson CG, Won M, Mehta MP
Neuro Oncol 2023 Jan 5;25(1):137-145. doi: 10.1093/neuonc/noac137. PMID: 35657335Free PMC Article
Is There Any Relationship Between Systemic Inflammatory Markers And Meningioma Grade?
Manjunath N, Mishra S, Garg K, Suri V, Sharma MC, Tandon V, Singh M, Suri A, Chandra PS, Kale SS
Neurol India 2022 Jan-Feb;70(1):223-230. doi: 10.4103/0028-3886.338647. PMID: 35263887
Does the Timing of Radiosurgery after Grade 1 Meningioma Resection Affect Long-Term Outcomes?
Bowden G, Faramand A, Mallella A, Wei Z, Patel K, Niranjan A, Lunsford LD
Stereotact Funct Neurosurg 2021;99(6):506-511. Epub 2021 Jul 21 doi: 10.1159/000517427. PMID: 34289489
WHO grade 1 meningioma recurrence: Are location and Simpson grade still relevant?
Gallagher MJ, Jenkinson MD, Brodbelt AR, Mills SJ, Chavredakis E
Clin Neurol Neurosurg 2016 Feb;141:117-21. Epub 2016 Jan 8 doi: 10.1016/j.clineuro.2016.01.006. PMID: 26780494

Diagnosis

Low-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539.
Rogers CL, Pugh SL, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Barani IJ, Braunstein S, Bovi JA, de Groot JF, Whitton AC, Lindhorst SM, Deb N, Shrieve DC, Shu HK, Bloom B, Machtay M, Mishra MV, Robinson CG, Won M, Mehta MP
Neuro Oncol 2023 Jan 5;25(1):137-145. doi: 10.1093/neuonc/noac137. PMID: 35657335Free PMC Article
Distinct clinical outcome of microcystic meningioma as a WHO grade 1 meningioma subtype.
Ren L, Hua L, Bao Z, Deng J, Wang D, Chen J, Chen H, Juratli TA, Wakimoto H, Gong Y
J Neurooncol 2023 Jan;161(2):193-202. Epub 2022 May 25 doi: 10.1007/s11060-022-04034-3. PMID: 35612696
Epigenetic and genomic profiling of chordoid meningioma: implications for clinical management.
Daoud EV, Zhu K, Mickey B, Mohamed H, Wen M, Delorenzo M, Tran I, Serrano J, Hatanpaa KJ, Raisanen JM, Snuderl M, Cai C
Acta Neuropathol Commun 2022 Apr 19;10(1):56. doi: 10.1186/s40478-022-01362-3. PMID: 35440040Free PMC Article
Is There Any Relationship Between Systemic Inflammatory Markers And Meningioma Grade?
Manjunath N, Mishra S, Garg K, Suri V, Sharma MC, Tandon V, Singh M, Suri A, Chandra PS, Kale SS
Neurol India 2022 Jan-Feb;70(1):223-230. doi: 10.4103/0028-3886.338647. PMID: 35263887
WHO grade 1 meningioma recurrence: Are location and Simpson grade still relevant?
Gallagher MJ, Jenkinson MD, Brodbelt AR, Mills SJ, Chavredakis E
Clin Neurol Neurosurg 2016 Feb;141:117-21. Epub 2016 Jan 8 doi: 10.1016/j.clineuro.2016.01.006. PMID: 26780494

Therapy

A single-center experience with linear accelerator-based stereotactic radiotherapy for meningiomas: hypofractionation and radiosurgery.
Gawish A, Abdulayev N, El-Arayed S, Röllich B, Ochel HJ, Brunner TB
J Cancer Res Clin Oncol 2023 Jan;149(1):103-109. Epub 2022 Oct 28 doi: 10.1007/s00432-022-04450-y. PMID: 36307558Free PMC Article
Low-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539.
Rogers CL, Pugh SL, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Barani IJ, Braunstein S, Bovi JA, de Groot JF, Whitton AC, Lindhorst SM, Deb N, Shrieve DC, Shu HK, Bloom B, Machtay M, Mishra MV, Robinson CG, Won M, Mehta MP
Neuro Oncol 2023 Jan 5;25(1):137-145. doi: 10.1093/neuonc/noac137. PMID: 35657335Free PMC Article
Factors Associated with Treatment Failure and Radiosurgery-Related Edema in WHO Grade 1 and 2 Meningioma Patients Receiving Gamma Knife Radiosurgery.
O'Connor KP, Algan O, Vesely SK, Palejwala AH, Briggs RG, Conner AK, Cornwell BO, Andrews B, Sughrue ME, Glenn CA
World Neurosurg 2019 Oct;130:e558-e565. Epub 2019 Jul 9 doi: 10.1016/j.wneu.2019.06.152. PMID: 31299310
IFN-α for recurrent surgery- and radiation-refractory high-grade meningioma: a retrospective case series.
Chamberlain MC
CNS Oncol 2013 May;2(3):227-35. doi: 10.2217/cns.13.17. PMID: 25054463Free PMC Article
Hydroxyurea for recurrent surgery and radiation refractory meningioma: a retrospective case series.
Chamberlain MC, Johnston SK
J Neurooncol 2011 Sep;104(3):765-71. Epub 2011 Feb 13 doi: 10.1007/s11060-011-0541-5. PMID: 21318318

Prognosis

Distinct clinical outcome of microcystic meningioma as a WHO grade 1 meningioma subtype.
Ren L, Hua L, Bao Z, Deng J, Wang D, Chen J, Chen H, Juratli TA, Wakimoto H, Gong Y
J Neurooncol 2023 Jan;161(2):193-202. Epub 2022 May 25 doi: 10.1007/s11060-022-04034-3. PMID: 35612696
Epigenetic and genomic profiling of chordoid meningioma: implications for clinical management.
Daoud EV, Zhu K, Mickey B, Mohamed H, Wen M, Delorenzo M, Tran I, Serrano J, Hatanpaa KJ, Raisanen JM, Snuderl M, Cai C
Acta Neuropathol Commun 2022 Apr 19;10(1):56. doi: 10.1186/s40478-022-01362-3. PMID: 35440040Free PMC Article
Is There Any Relationship Between Systemic Inflammatory Markers And Meningioma Grade?
Manjunath N, Mishra S, Garg K, Suri V, Sharma MC, Tandon V, Singh M, Suri A, Chandra PS, Kale SS
Neurol India 2022 Jan-Feb;70(1):223-230. doi: 10.4103/0028-3886.338647. PMID: 35263887
Does the Timing of Radiosurgery after Grade 1 Meningioma Resection Affect Long-Term Outcomes?
Bowden G, Faramand A, Mallella A, Wei Z, Patel K, Niranjan A, Lunsford LD
Stereotact Funct Neurosurg 2021;99(6):506-511. Epub 2021 Jul 21 doi: 10.1159/000517427. PMID: 34289489
WHO grade 1 meningioma recurrence: Are location and Simpson grade still relevant?
Gallagher MJ, Jenkinson MD, Brodbelt AR, Mills SJ, Chavredakis E
Clin Neurol Neurosurg 2016 Feb;141:117-21. Epub 2016 Jan 8 doi: 10.1016/j.clineuro.2016.01.006. PMID: 26780494

Clinical prediction guides

A single-center experience with linear accelerator-based stereotactic radiotherapy for meningiomas: hypofractionation and radiosurgery.
Gawish A, Abdulayev N, El-Arayed S, Röllich B, Ochel HJ, Brunner TB
J Cancer Res Clin Oncol 2023 Jan;149(1):103-109. Epub 2022 Oct 28 doi: 10.1007/s00432-022-04450-y. PMID: 36307558Free PMC Article
Low-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539.
Rogers CL, Pugh SL, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Barani IJ, Braunstein S, Bovi JA, de Groot JF, Whitton AC, Lindhorst SM, Deb N, Shrieve DC, Shu HK, Bloom B, Machtay M, Mishra MV, Robinson CG, Won M, Mehta MP
Neuro Oncol 2023 Jan 5;25(1):137-145. doi: 10.1093/neuonc/noac137. PMID: 35657335Free PMC Article
Radiographic Differentiation of Secretory Meningiomas and WHO Grade 2 Meningiomas: When Atypical Features Are Not Always Predictive of Atypical Tumors.
Trivedi MM, Momin AA, Shao J, Soni P, Almeida JP, Lee J, Recinos PF, Kshettry VR
World Neurosurg 2022 Sep;165:e386-e392. Epub 2022 Jun 17 doi: 10.1016/j.wneu.2022.06.061. PMID: 35724883
Is There Any Relationship Between Systemic Inflammatory Markers And Meningioma Grade?
Manjunath N, Mishra S, Garg K, Suri V, Sharma MC, Tandon V, Singh M, Suri A, Chandra PS, Kale SS
Neurol India 2022 Jan-Feb;70(1):223-230. doi: 10.4103/0028-3886.338647. PMID: 35263887
WHO grade 1 meningioma recurrence: Are location and Simpson grade still relevant?
Gallagher MJ, Jenkinson MD, Brodbelt AR, Mills SJ, Chavredakis E
Clin Neurol Neurosurg 2016 Feb;141:117-21. Epub 2016 Jan 8 doi: 10.1016/j.clineuro.2016.01.006. PMID: 26780494

Recent systematic reviews

Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: International Stereotactic Radiosurgery Society Systematic Review, Meta-Analysis and Practice Guideline.
Marchetti M, Sahgal A, De Salles AAF, Levivier M, Ma L, Paddick I, Pollock BE, Regis J, Sheehan J, Suh JH, Yomo S, Fariselli L
Neurosurgery 2020 Oct 15;87(5):879-890. doi: 10.1093/neuros/nyaa169. PMID: 32463867Free PMC Article

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