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Malignant Ovarian Epithelial Tumor

MedGen UID:
273560
•Concept ID:
C1518236
•
Neoplastic Process
Synonyms: Malignant Ovarian Surface Epithelial-Stromal Neoplasm; Malignant Ovarian Surface Epithelial-Stromal Tumor

Definition

An invasive malignant tumor that originates from the surface epithelium of the ovary. It is composed of malignant epithelial cells and stroma. Representative examples include serous adenocarcinoma, mucinous adenocarcinoma, endometrioid adenocarcinoma, clear cell adenocarcinoma, and malignant Brenner tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Ovarian Epithelial Tumor

Professional guidelines

PubMed

Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup.
Vergote I, Gonzalez-Martin A, Lorusso D, Gourley C, Mirza MR, Kurtz JE, Okamoto A, Moore K, Kridelka F, McNeish I, Reuss A, Votan B, du Bois A, Mahner S, Ray-Coquard I, Kohn EC, Berek JS, Tan DSP, Colombo N, Zang R, Concin N, O'Donnell D, Rauh-Hain A, Herrington CS, Marth C, Poveda A, Fujiwara K, Stuart GCE, Oza AM, Bookman MA; participants of the 6th Gynecologic Cancer InterGroup (GCIG) Ovarian Cancer Consensus Conference on Clinical Research
Lancet Oncol 2022 Aug;23(8):e374-e384. doi: 10.1016/S1470-2045(22)00139-5. PMID: 35901833Free PMC Article
Diagnosis and Treatment of Ovarian Cancer.
Orr B, Edwards RP
Hematol Oncol Clin North Am 2018 Dec;32(6):943-964. doi: 10.1016/j.hoc.2018.07.010. PMID: 30390767
Management of borderline ovarian tumours.
Gershenson DM
Best Pract Res Clin Obstet Gynaecol 2017 May;41:49-59. Epub 2016 Oct 3 doi: 10.1016/j.bpobgyn.2016.09.012. PMID: 27780698

Recent clinical studies

Etiology

Expression of inflammatory cytokines in ovarian epithelial cancer and their correlation.
Tang YJ, Dou HT, Zhang QH, Liu JJ, Yang XS
J Biol Regul Homeost Agents 2017 Apr-Jun;31(2):413-418. PMID: 28685546

Diagnosis

MRI of Borderline Epithelial Ovarian Tumors: Pathologic Correlation and Diagnostic Challenges.
Tsuboyama T, Sato K, Ota T, Fukui H, Onishi H, Nakamoto A, Tatsumi M, Tomiyama N
Radiographics 2022 Nov-Dec;42(7):2095-2111. Epub 2022 Sep 9 doi: 10.1148/rg.220068. PMID: 36083804

Therapy

Cystadenocarcinoma of the ovary in a 4-year-old: benign transformation during therapy.
Hong SJ, Lurain JR, Tsukada Y, Piver MS, Humbert JR, Freeman AI
Cancer 1980 Apr 15;45(8):2227-30. doi: 10.1002/1097-0142(19800415)45:8<2227::aid-cncr2820450837>3.0.co;2-#. PMID: 7370965

Prognosis

MRI of Borderline Epithelial Ovarian Tumors: Pathologic Correlation and Diagnostic Challenges.
Tsuboyama T, Sato K, Ota T, Fukui H, Onishi H, Nakamoto A, Tatsumi M, Tomiyama N
Radiographics 2022 Nov-Dec;42(7):2095-2111. Epub 2022 Sep 9 doi: 10.1148/rg.220068. PMID: 36083804
Expression of inflammatory cytokines in ovarian epithelial cancer and their correlation.
Tang YJ, Dou HT, Zhang QH, Liu JJ, Yang XS
J Biol Regul Homeost Agents 2017 Apr-Jun;31(2):413-418. PMID: 28685546

Clinical prediction guides

MRI of Borderline Epithelial Ovarian Tumors: Pathologic Correlation and Diagnostic Challenges.
Tsuboyama T, Sato K, Ota T, Fukui H, Onishi H, Nakamoto A, Tatsumi M, Tomiyama N
Radiographics 2022 Nov-Dec;42(7):2095-2111. Epub 2022 Sep 9 doi: 10.1148/rg.220068. PMID: 36083804
Expression of inflammatory cytokines in ovarian epithelial cancer and their correlation.
Tang YJ, Dou HT, Zhang QH, Liu JJ, Yang XS
J Biol Regul Homeost Agents 2017 Apr-Jun;31(2):413-418. PMID: 28685546
Epithelial metaplastic changes in ovarian endometriosis.
Fukunaga M, Ushigome S
Mod Pathol 1998 Aug;11(8):784-8. PMID: 9720509

Supplemental Content

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