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Testicular Neuroendocrine Tumor, Prepubertal-Type

MedGen UID:
277807
Concept ID:
C1336705
Neoplastic Process
Synonyms: Prepubertal Type Testicular Neuroendocrine Tumor; Prepubertal-Type Testicular Neuroendocrine Tumor; Testicular Neuroendocrine Tumor, Prepubertal Type

Definition

A rare, usually well-differentiated neuroendocrine tumor that arises from the testis. It usually affects adults, and a minority of patients have carcinoid syndrome. It may be pure or less frequently associated with a testicular teratoma. The majority of cases are not associated with isochromosome 12p or germ cell neoplasia in situ. The clinical course is usually benign. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTesticular Neuroendocrine Tumor, Prepubertal-Type

Recent clinical studies

Etiology

Michalová K, Hes O, Michal M
Cesk Patol 2022 Fall;67(4):198-204. PMID: 36513505
Moch H, Amin MB, Berney DM, Compérat EM, Gill AJ, Hartmann A, Menon S, Raspollini MR, Rubin MA, Srigley JR, Hoon Tan P, Tickoo SK, Tsuzuki T, Turajlic S, Cree I, Netto GJ
Eur Urol 2022 Nov;82(5):458-468. Epub 2022 Jul 16 doi: 10.1016/j.eururo.2022.06.016. PMID: 35853783
Wagner T, Scandura G, Roe A, Beltran L, Shamash J, Alfrangis C, Daugaard G, Grantham M, Berney D
Mod Pathol 2020 Apr;33(4):713-721. Epub 2019 Nov 6 doi: 10.1038/s41379-019-0404-8. PMID: 31695156

Diagnosis

Michalová K, Hes O, Michal M
Cesk Patol 2022 Fall;67(4):198-204. PMID: 36513505
Gupta S, Erickson LA
Mayo Clin Proc 2022 Oct;97(10):1956-1957. doi: 10.1016/j.mayocp.2022.07.015. PMID: 36202503
Moch H, Amin MB, Berney DM, Compérat EM, Gill AJ, Hartmann A, Menon S, Raspollini MR, Rubin MA, Srigley JR, Hoon Tan P, Tickoo SK, Tsuzuki T, Turajlic S, Cree I, Netto GJ
Eur Urol 2022 Nov;82(5):458-468. Epub 2022 Jul 16 doi: 10.1016/j.eururo.2022.06.016. PMID: 35853783
Berney DM, Cree I, Rao V, Moch H, Srigley JR, Tsuzuki T, Amin MB, Comperat EM, Hartmann A, Menon S, Netto GJ, Rubin MA, Turajlic S, Raspollini MR, Tickoo SK
Histopathology 2022 Oct;81(4):459-466. Epub 2022 Jul 1 doi: 10.1111/his.14675. PMID: 35502823Free PMC Article
Wagner T, Scandura G, Roe A, Beltran L, Shamash J, Alfrangis C, Daugaard G, Grantham M, Berney D
Mod Pathol 2020 Apr;33(4):713-721. Epub 2019 Nov 6 doi: 10.1038/s41379-019-0404-8. PMID: 31695156

Prognosis

Berney DM, Cree I, Rao V, Moch H, Srigley JR, Tsuzuki T, Amin MB, Comperat EM, Hartmann A, Menon S, Netto GJ, Rubin MA, Turajlic S, Raspollini MR, Tickoo SK
Histopathology 2022 Oct;81(4):459-466. Epub 2022 Jul 1 doi: 10.1111/his.14675. PMID: 35502823Free PMC Article
Wagner T, Scandura G, Roe A, Beltran L, Shamash J, Alfrangis C, Daugaard G, Grantham M, Berney D
Mod Pathol 2020 Apr;33(4):713-721. Epub 2019 Nov 6 doi: 10.1038/s41379-019-0404-8. PMID: 31695156

Clinical prediction guides

Wagner T, Scandura G, Roe A, Beltran L, Shamash J, Alfrangis C, Daugaard G, Grantham M, Berney D
Mod Pathol 2020 Apr;33(4):713-721. Epub 2019 Nov 6 doi: 10.1038/s41379-019-0404-8. PMID: 31695156

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