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Squamous cell carcinoma of the small intestine

MedGen UID:
313711
Concept ID:
C1710111
Neoplastic Process
Synonyms: small intestinal squamous cell cancer; Small Intestinal Squamous Cell Carcinoma; small intestinal squamous cell carcinoma; small intestine squamous cell carcinoma; Squamous cell carcinoma of the small bowel; squamous cell carcinoma of the small bowel; squamous cell carcinoma of the small intestine
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0018509
Orphanet: ORPHA423968

Definition

Squamous cell carcinoma of the small intestine is an extremely rare, malignant, epithelial tumor of the small intestine (most often localized in the duodenum). Presenting symptoms are often nonspecific, such as weight loss, epigastric pain, anorexia, weakness, fatigue, vomiting and abdominal distension, and vary depending on localization of the tumor. Gastrointestinal bleeding and perforation may occur in advanced cases. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSquamous cell carcinoma of the small intestine

Professional guidelines

PubMed

Nishizawa Y, Kobayashi A, Saito N, Nagai K, Sugito M, Ito M, Nishizawa Y
Surg Today 2012 Feb;42(3):233-7. Epub 2011 Nov 3 doi: 10.1007/s00595-011-0005-8. PMID: 22045233
Pesko P, Sabljak P, Bjelovic M, Stojakov D, Simic A, Nenadic B, Bumbasirevic M, Trajkovic G, Djukic V
Dis Esophagus 2006;19(4):248-53. doi: 10.1111/j.1442-2050.2006.00585.x. PMID: 16866855
Leu YS, Hsiao HT, Chang YC, Yang CC, Lee JC, Chen YJ, Chang YF
Acta Otolaryngol 2005 Jun;125(6):642-6. doi: 10.1080/00016480510027457. PMID: 16076714

Recent clinical studies

Etiology

Piovani D, Hassan C, Repici A, Rimassa L, Carlo-Stella C, Nikolopoulos GK, Riboli E, Bonovas S
Gastroenterology 2022 Sep;163(3):671-684. Epub 2022 May 26 doi: 10.1053/j.gastro.2022.05.038. PMID: 35643170
Hong CR, Buckley CD, Wong WW, Anekal PV, Dickson BD, Bogle G, Hicks KO, Hay MP, Wilson WR
Radiother Oncol 2022 Jan;166:162-170. Epub 2021 Nov 30 doi: 10.1016/j.radonc.2021.11.027. PMID: 34861268
Leigh N, Solomon D, Pletcher E, Sullivan B, Sarpel U, Labow DM, Magge DR, Golas BJ
Am J Surg 2020 Nov;220(5):1242-1248. Epub 2020 Jul 1 doi: 10.1016/j.amjsurg.2020.06.050. PMID: 32646581
Okamura A, Watanabe M, Kozuki R, Toihata T, Yuda M, Imamura Y, Mine S
Langenbecks Arch Surg 2018 Dec;403(8):977-984. Epub 2018 Oct 25 doi: 10.1007/s00423-018-1722-x. PMID: 30361828
Andersson A, Bergdahl L
Am Surg 1976 Mar;42(3):173-7. PMID: 1259248

Diagnosis

Piovani D, Hassan C, Repici A, Rimassa L, Carlo-Stella C, Nikolopoulos GK, Riboli E, Bonovas S
Gastroenterology 2022 Sep;163(3):671-684. Epub 2022 May 26 doi: 10.1053/j.gastro.2022.05.038. PMID: 35643170
McCabe P, Rabkin J, Goyal B
Clin Gastroenterol Hepatol 2021 May;19(5):e48. Epub 2020 Mar 19 doi: 10.1016/j.cgh.2020.03.029. PMID: 32200081
Namikawa K, Hirasawa T, Yoshio T, Fujisaki J, Ozawa T, Ishihara S, Aoki T, Yamada A, Koike K, Suzuki H, Tada T
Expert Rev Gastroenterol Hepatol 2020 Aug;14(8):689-706. Epub 2020 Jun 17 doi: 10.1080/17474124.2020.1779058. PMID: 32500760
Chaparro Mirete M, López-López V, Robles Campos R
Rev Esp Enferm Dig 2020 Mar;112(3):239. doi: 10.17235/reed.2020.6503/2019. PMID: 32022569
Thomas RM, Sobin LH
Cancer 1995 Jan 1;75(1 Suppl):154-70. doi: 10.1002/1097-0142(19950101)75:1+<154::aid-cncr2820751305>3.0.co;2-z. PMID: 8000994

Therapy

Senoh H, Kasai T, Hirai S, Furukawa Y, Misumi K, Goto Y, Takanobu K, Matsumoto M, Fukushima S, Aiso S
J Occup Health 2023 Jan;65(1):e12388. doi: 10.1002/1348-9585.12388. PMID: 36756793Free PMC Article
Piovani D, Hassan C, Repici A, Rimassa L, Carlo-Stella C, Nikolopoulos GK, Riboli E, Bonovas S
Gastroenterology 2022 Sep;163(3):671-684. Epub 2022 May 26 doi: 10.1053/j.gastro.2022.05.038. PMID: 35643170
Sugimoto K, Uejima S, Uchiyama Y, Yasue R, Nambu K, Ishikawa J, Koma Y, Akita T, Toh T, Fujimoto T
Medicine (Baltimore) 2021 Feb 19;100(7):e24806. doi: 10.1097/MD.0000000000024806. PMID: 33607843Free PMC Article
Park B, Kim HK, Choi YS, Kim J, Zo JI, Shim YM
Thorac Cardiovasc Surg 2016 Oct;64(7):611-618. Epub 2016 May 5 doi: 10.1055/s-0036-1583166. PMID: 27148930
Daiko H, Hayashi R, Saikawa M, Sakuraba M, Yamazaki M, Miyazaki M, Ugumori T, Asai M, Oyama W, Ebihara S
J Surg Oncol 2007 Aug 1;96(2):166-72. doi: 10.1002/jso.20795. PMID: 17443746

Prognosis

Soni S, Elhence P, Varshney VK, Suman S
BMJ Case Rep 2021 Jan 7;14(1) doi: 10.1136/bcr-2020-236477. PMID: 33414110Free PMC Article
Okamura A, Watanabe M, Kozuki R, Toihata T, Yuda M, Imamura Y, Mine S
Langenbecks Arch Surg 2018 Dec;403(8):977-984. Epub 2018 Oct 25 doi: 10.1007/s00423-018-1722-x. PMID: 30361828
Dwivedi RC, Kazi R, Agrawal N, Chisholm E, St Rose S, Elmiyeh B, Rennie C, Pepper C, Clarke PM, Kerawala CJ, Rhys-Evans PH, Harrington KJ, Nutting CM
Oral Oncol 2010 May;46(5):330-5. Epub 2010 Feb 26 doi: 10.1016/j.oraloncology.2010.01.013. PMID: 20189444
Thomas RM, Sobin LH
Cancer 1995 Jan 1;75(1 Suppl):154-70. doi: 10.1002/1097-0142(19950101)75:1+<154::aid-cncr2820751305>3.0.co;2-z. PMID: 8000994
Lee YT
Cancer Treat Rev 1983 Jun;10(2):91-101. doi: 10.1016/0305-7372(83)90007-5. PMID: 6347377

Clinical prediction guides

Chen VE, Gillespie EF, Manger RP, Skerritt LA, Tran JH, Proudfoot JA, Sherer MV, Einck JP, Mell LK, Moore KL, Yashar CM
Med Dosim 2019 Summer;44(2):102-106. Epub 2018 Mar 21 doi: 10.1016/j.meddos.2018.02.010. PMID: 29573921
Okamura A, Watanabe M, Kozuki R, Toihata T, Yuda M, Imamura Y, Mine S
Langenbecks Arch Surg 2018 Dec;403(8):977-984. Epub 2018 Oct 25 doi: 10.1007/s00423-018-1722-x. PMID: 30361828
Park B, Kim HK, Choi YS, Kim J, Zo JI, Shim YM
Thorac Cardiovasc Surg 2016 Oct;64(7):611-618. Epub 2016 May 5 doi: 10.1055/s-0036-1583166. PMID: 27148930
Hoshimoto S, Aiura K, Shito M, Kakefuda T, Sugiura H
World J Surg Oncol 2015 Sep 29;13:287. doi: 10.1186/s12957-015-0709-0. PMID: 26420726Free PMC Article
Lewis JD, Deren JJ, Lichtenstein GR
Gastroenterol Clin North Am 1999 Jun;28(2):459-77, x. doi: 10.1016/s0889-8553(05)70065-0. PMID: 10372277

Recent systematic reviews

Piovani D, Hassan C, Repici A, Rimassa L, Carlo-Stella C, Nikolopoulos GK, Riboli E, Bonovas S
Gastroenterology 2022 Sep;163(3):671-684. Epub 2022 May 26 doi: 10.1053/j.gastro.2022.05.038. PMID: 35643170
Parra-Medina R, Moreno-Lucero P, Jimenez-Moreno J, Parra-Morales AM, Romero-Rojas A
PLoS One 2019;14(5):e0216647. Epub 2019 May 14 doi: 10.1371/journal.pone.0216647. PMID: 31086397Free PMC Article

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