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Colorectal carcinoma(CRC)

MedGen UID:
3170
Concept ID:
C0009402
Neoplastic Process
Synonyms: Cancer, Colorectal; Cancers, Colorectal; Carcinoma, Colorectal; Carcinomas, Colorectal; Colorectal Cancer; Colorectal Cancers; Colorectal Carcinoma; Colorectal Carcinomas
 
Monarch Initiative: MONDO:0024331
OMIM®: 114500; 172411; 191170; 516000; 516004; 516020; 516030; 516040

Definition

A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Bergamaschi L, Chiaravalli S, Signoroni S, Di Bartolomeo M, Ferrari A
Expert Opin Pharmacother 2023 Sep-Dec;24(14):1527-1535. Epub 2023 Jun 29 doi: 10.1080/14656566.2023.2230123. PMID: 37358925
Akdeniz N, Kaplan MA, Uncu D, İnanç M, Kaya S, Dane F, Küçüköner M, Demirci A, Bilici M, Durnalı AG, Koral L, Şendur MAN, Erol C, Türkmen E, Ölmez ÖF, Açıkgöz Ö, Laçin Ş, Şahinli H, Urakçı Z, Işıkdoğan A
Int J Colorectal Dis 2021 Jun;36(6):1311-1319. Epub 2021 Feb 14 doi: 10.1007/s00384-021-03888-9. PMID: 33586012
Goddard AF, James MW, McIntyre AS, Scott BB; British Society of Gastroenterology
Gut 2011 Oct;60(10):1309-16. Epub 2011 May 11 doi: 10.1136/gut.2010.228874. PMID: 21561874

Curated

DailyMed Drug Label, Capecitabine, 2021

Recent clinical studies

Etiology

Rasheed Abubakir S, Hidayat HJ
Cell Mol Biol (Noisy-le-grand) 2023 Sep 30;69(9):177-182. doi: 10.14715/cmb/2023.69.9.27. PMID: 37807315
Bergamaschi L, Chiaravalli S, Signoroni S, Di Bartolomeo M, Ferrari A
Expert Opin Pharmacother 2023 Sep-Dec;24(14):1527-1535. Epub 2023 Jun 29 doi: 10.1080/14656566.2023.2230123. PMID: 37358925
Bell PD, Pai RK
Histopathology 2022 Dec;81(6):696-714. Epub 2022 Jul 15 doi: 10.1111/his.14713. PMID: 35758208
Lesko J, Rastović P, Azinović A, Ðurasović S, Bogut A, Zovko J, Pavlović M, Zovko Z
Med Glas (Zenica) 2020 Feb 1;17(1):151-157. doi: 10.17392/1079-20. PMID: 31845566
Niederreiter L, Adolph TE, Tilg H
Dig Liver Dis 2018 Jul;50(7):647-652. Epub 2018 Apr 3 doi: 10.1016/j.dld.2018.03.030. PMID: 29705028

Diagnosis

Weber F, Jung R, Treeck O, Buechler C
Anticancer Res 2023 Feb;43(2):831-839. doi: 10.21873/anticanres.16225. PMID: 36697076
Beech C, Hechtman JF
Surg Pathol Clin 2021 Sep;14(3):429-441. doi: 10.1016/j.path.2021.05.007. PMID: 34373094
Johncilla M, Yantiss RK
Surg Pathol Clin 2020 Sep;13(3):503-520. Epub 2020 Jul 9 doi: 10.1016/j.path.2020.05.008. PMID: 32773197
Hissong E, Pittman ME
Crit Rev Clin Lab Sci 2020 Jan;57(1):22-36. Epub 2019 Oct 11 doi: 10.1080/10408363.2019.1670614. PMID: 31603697
Bhalla A, Zulfiqar M, Bluth MH
Clin Lab Med 2018 Jun;38(2):311-342. doi: 10.1016/j.cll.2018.02.008. PMID: 29776633

Therapy

Garin E, Guiu B, Edeline J, Rolland Y, Palard X
Cardiovasc Intervent Radiol 2022 Nov;45(11):1608-1621. Epub 2022 Aug 18 doi: 10.1007/s00270-022-03215-x. PMID: 35982334
Zhang KL, Zhu WW, Wang SH, Gao C, Pan JJ, Du ZG, Lu L, Jia HL, Dong QZ, Chen JH, Lu M, Qin LX
Theranostics 2021;11(13):6560-6572. Epub 2021 Apr 27 doi: 10.7150/thno.55609. PMID: 33995676Free PMC Article
Mody K, Baldeo C, Bekaii-Saab T
Cancer J 2018 Jul/Aug;24(4):165-170. doi: 10.1097/PPO.0000000000000328. PMID: 30119079
Dubel GJ, Soares GM
Surg Oncol Clin N Am 2008 Oct;17(4):957-85, xii. doi: 10.1016/j.soc.2008.04.008. PMID: 18722928
Hasan J, Jayson GC
Expert Opin Biol Ther 2001 Jul;1(4):703-18. doi: 10.1517/14712598.1.4.703. PMID: 11727506

Prognosis

Mathey MD, Pennella CL, Zubizarreta P
Arch Argent Pediatr 2021 Oct;119(5):e487-e498. doi: 10.5546/aap.2021.eng.e487. PMID: 34569749
Zhong A, Tian Y, Zhang H, Lai M
J Surg Oncol 2018 Apr;117(5):1029-1037. Epub 2018 Mar 12 doi: 10.1002/jso.24978. PMID: 29529342
Perren TJ
Ann Oncol 2016 Apr;27 Suppl 1:i53-i57. doi: 10.1093/annonc/mdw087. PMID: 27141073
Benedict M, Galvao Neto A, Zhang X
World J Gastroenterol 2015 Dec 7;21(45):12735-41. doi: 10.3748/wjg.v21.i45.12735. PMID: 26668498Free PMC Article
Halle M, Schoenberg MH
Dtsch Arztebl Int 2009 Oct;106(44):722-7. Epub 2009 Oct 30 doi: 10.3238/arztebl.2009.0722. PMID: 19997551Free PMC Article

Clinical prediction guides

Weber F, Jung R, Treeck O, Buechler C
Anticancer Res 2023 Feb;43(2):831-839. doi: 10.21873/anticanres.16225. PMID: 36697076
Benedict M, Galvao Neto A, Zhang X
World J Gastroenterol 2015 Dec 7;21(45):12735-41. doi: 10.3748/wjg.v21.i45.12735. PMID: 26668498Free PMC Article
Ritterhouse LL, Barletta JA
Semin Diagn Pathol 2015 Sep;32(5):400-8. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2015.02.010. PMID: 25744437
Lam AK, Chan SS, Leung M
World J Gastroenterol 2014 Jun 14;20(22):6815-20. doi: 10.3748/wjg.v20.i22.6815. PMID: 24944471Free PMC Article
Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D'Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Hafezi-Bakhtiari S, Wouters BG, Roehrl M, Nguyen L, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S, Sinicrope FA, Scripcariu V, Ascierto PA, Marincola FM, Fox BA, Pagès F
J Pathol 2014 Jan;232(2):199-209. doi: 10.1002/path.4287. PMID: 24122236Free PMC Article

Recent systematic reviews

Afolabi H, Md Salleh S, Zakaria Z, Seng CE, Mohd Nafil SNB, Abdul Aziz AAB, Wada Y, Irekeola A
Biomed Res Int 2022;2022:5824183. Epub 2022 Jun 23 doi: 10.1155/2022/5824183. PMID: 35782059Free PMC Article
Falz R, Bischoff C, Thieme R, Lässing J, Mehdorn M, Stelzner S, Busse M, Gockel I
J Cancer Res Clin Oncol 2022 Sep;148(9):2187-2213. Epub 2022 Jun 13 doi: 10.1007/s00432-022-04088-w. PMID: 35695931Free PMC Article
Pyo JS, Sohn JH, Kang G
Hum Pathol 2016 Jul;53:91-6. Epub 2016 Mar 19 doi: 10.1016/j.humpath.2016.02.018. PMID: 27001432
Esin E, Yalcin S
Cancer Treat Rev 2016 Jan;42:82-90. Epub 2015 Nov 10 doi: 10.1016/j.ctrv.2015.10.012. PMID: 26608114
da Costa Vieira RA, Tramonte MS, Lopes LF
Int J Colorectal Dis 2015 Aug;30(8):1001-6. Epub 2015 Apr 28 doi: 10.1007/s00384-015-2202-1. PMID: 25916603

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