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Prominent interdigital folds

MedGen UID:
356420
Concept ID:
C1866000
Finding
HPO: HP:0006189

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProminent interdigital folds

Conditions with this feature

Odonto-tricho-ungual-digito-palmar syndrome
MedGen UID:
400891
Concept ID:
C1865998
Disease or Syndrome
This syndrome has characteristics of neonatal teeth, trichodystrophy and malformations of the hands and feet. To date, it has been reported in 21 patients and is transmitted as an autosomal dominant trait.

Recent clinical studies

Etiology

Cheuk W, Walford N, Lou J, Lee AK, Fung CF, Au KH, Mak LS, Chan JK
Am J Surg Pathol 2001 Nov;25(11):1372-9. doi: 10.1097/00000478-200111000-00004. PMID: 11684953
Merkel KH
Arch Orthop Trauma Surg (1978) 1980;97(3):185-91. doi: 10.1007/BF00389725. PMID: 6893797

Diagnosis

Tabaran AF, Armien AG, Pluhar GE, O'Sullivan MG
Vet Pathol 2022 Sep;59(5):759-767. Epub 2022 Jun 8 doi: 10.1177/03009858221100436. PMID: 35674149
Cheuk W, Walford N, Lou J, Lee AK, Fung CF, Au KH, Mak LS, Chan JK
Am J Surg Pathol 2001 Nov;25(11):1372-9. doi: 10.1097/00000478-200111000-00004. PMID: 11684953
Chan JK, Tsang WY, Ng CS, Tang SK, Yu HC, Lee AW
Am J Surg Pathol 1994 Feb;18(2):148-57. doi: 10.1097/00000478-199402000-00004. PMID: 8291653

Therapy

Merkel KH
Arch Orthop Trauma Surg (1978) 1980;97(3):185-91. doi: 10.1007/BF00389725. PMID: 6893797
KEMP NE
J Biophys Biochem Cytol 1956 May 25;2(3):281-92. doi: 10.1083/jcb.2.3.281. PMID: 13331960Free PMC Article

Clinical prediction guides

Jentink N, Purnell C, Kable B, Swulius MT, Grigoryev SA
Mol Cell 2023 Sep 21;83(18):3236-3252.e7. Epub 2023 Sep 7 doi: 10.1016/j.molcel.2023.08.017. PMID: 37683647Free PMC Article
Tanaka H, Saito S, Sasaki H, Arai H, Oki T, Shioya N
Pathol Int 1994 Apr;44(4):268-79. doi: 10.1111/j.1440-1827.1994.tb03364.x. PMID: 7519104
Schmukler AG, Garcia EE
Int J Psychoanal 1990;71 ( Pt 2):297-300. PMID: 1694834
KEMP NE
J Biophys Biochem Cytol 1956 May 25;2(3):281-92. doi: 10.1083/jcb.2.3.281. PMID: 13331960Free PMC Article

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