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Seminomatous Component Present

MedGen UID:
362821
•Concept ID:
C1882999
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSeminomatous Component Present

Professional guidelines

PubMed

Surgical Management of Cervical Non-seminomatous Germ Cell Tumor Metastases.
Nwosu OI, Jones AJ, Alwani M, Einhorn LH, Moore MG, Mantravadi AV
Laryngoscope 2021 Jul;131(7):1528-1534. Epub 2021 Jan 9 doi: 10.1002/lary.29364. PMID: 33421136
Brain metastasis from non-seminomatous germ cell tumors of the testis: indications for aggressive treatment.
Salvati M, Piccirilli M, Raco A, Santoro A, Frati R, Lenzi J, Lanzetta G, Agrillo A, Frati A
Neurosurg Rev 2006 Apr;29(2):130-7. Epub 2005 Nov 23 doi: 10.1007/s10143-005-0004-6. PMID: 16328533

Recent clinical studies

Etiology

Surgical Management of Cervical Non-seminomatous Germ Cell Tumor Metastases.
Nwosu OI, Jones AJ, Alwani M, Einhorn LH, Moore MG, Mantravadi AV
Laryngoscope 2021 Jul;131(7):1528-1534. Epub 2021 Jan 9 doi: 10.1002/lary.29364. PMID: 33421136
Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists.
Lobo J, Costa AL, Vilela-Salgueiro B, Rodrigues Â, Guimarães R, Cantante M, Lopes P, Antunes L, Jerónimo C, Henrique R
Hum Pathol 2018 Dec;82:113-124. Epub 2018 Jul 21 doi: 10.1016/j.humpath.2018.07.016. PMID: 30041024
Growing teratoma syndrome: clinical and radiographic characteristics.
Lee DJ, Djaladat H, Tadros NN, Movassaghi M, Tejura T, Duddalwar V, Daneshmand S
Int J Urol 2014 Sep;21(9):905-8. Epub 2014 Apr 21 doi: 10.1111/iju.12466. PMID: 24750260
Clinical use of serum TRA-1-60 as tumor marker in patients with germ cell cancer.
Lajer H, Daugaard G, Andersson AM, Skakkebaek NE
Int J Cancer 2002 Jul 10;100(2):244-6. doi: 10.1002/ijc.10459. PMID: 12115576
Histologically pure seminoma with elevated alpha-fetoprotein: a clinicopathologic study of ten cases.
Nazeer T, Ro JY, Amato RJ, Park YW, Ordonez NG, Ayala AG
Oncol Rep 1998 Nov-Dec;5(6):1425-9. doi: 10.3892/or.5.6.1425. PMID: 9769381

Diagnosis

Differential expression of preferentially expressed antigen in melanoma (PRAME) in testicular germ cell tumors - A comparative study with SOX17.
Zhou Y, Rothrock A, Murugan P, Li F, Bu L
Exp Mol Pathol 2022 Jun;126:104761. Epub 2022 Apr 4 doi: 10.1016/j.yexmp.2022.104761. PMID: 35390309
Successful treatment of radiotherapy and apatinib in patient with mediastinal mixed non-seminomatous germ cell tumor: A case report.
Ren C, Zhao J, Kang L, Di Y, Qiu G, Wang Q
Medicine (Baltimore) 2021 Oct 29;100(43):e27617. doi: 10.1097/MD.0000000000027617. PMID: 34713845Free PMC Article
Surgical Management of Cervical Non-seminomatous Germ Cell Tumor Metastases.
Nwosu OI, Jones AJ, Alwani M, Einhorn LH, Moore MG, Mantravadi AV
Laryngoscope 2021 Jul;131(7):1528-1534. Epub 2021 Jan 9 doi: 10.1002/lary.29364. PMID: 33421136
Growing teratoma syndrome: clinical and radiographic characteristics.
Lee DJ, Djaladat H, Tadros NN, Movassaghi M, Tejura T, Duddalwar V, Daneshmand S
Int J Urol 2014 Sep;21(9):905-8. Epub 2014 Apr 21 doi: 10.1111/iju.12466. PMID: 24750260
Testicular tumors--some new and a few perennial problems.
Young RH
Arch Pathol Lab Med 2008 Apr;132(4):548-64. doi: 10.5858/2008-132-548-TTNAAF. PMID: 18384207

Therapy

Successful treatment of radiotherapy and apatinib in patient with mediastinal mixed non-seminomatous germ cell tumor: A case report.
Ren C, Zhao J, Kang L, Di Y, Qiu G, Wang Q
Medicine (Baltimore) 2021 Oct 29;100(43):e27617. doi: 10.1097/MD.0000000000027617. PMID: 34713845Free PMC Article
Surgical Management of Cervical Non-seminomatous Germ Cell Tumor Metastases.
Nwosu OI, Jones AJ, Alwani M, Einhorn LH, Moore MG, Mantravadi AV
Laryngoscope 2021 Jul;131(7):1528-1534. Epub 2021 Jan 9 doi: 10.1002/lary.29364. PMID: 33421136
Detailed pathologic analysis on the co-occurrence of non-seminomatous germ cell tumor subtypes in matched orchiectomy and retroperitoneal lymph node dissections.
Spratt DE, Suresh K, Osawa T, Schipper M, Jackson WC, Abugharib A, Lebastchi A, Smith D, Montgomery JS, Palapattu GS, Priya Kunju L, Wu A, Lew M, Tomlins SA, Chinnaiyan AM, Weizer AZ, Hafez KS, Kaffenberger SD, Udager A, Mehra R
Med Oncol 2018 Jan 31;35(3):21. doi: 10.1007/s12032-018-1090-y. PMID: 29387987
Clinical use of serum TRA-1-60 as tumor marker in patients with germ cell cancer.
Lajer H, Daugaard G, Andersson AM, Skakkebaek NE
Int J Cancer 2002 Jul 10;100(2):244-6. doi: 10.1002/ijc.10459. PMID: 12115576
Histologically pure seminoma with elevated alpha-fetoprotein: a clinicopathologic study of ten cases.
Nazeer T, Ro JY, Amato RJ, Park YW, Ordonez NG, Ayala AG
Oncol Rep 1998 Nov-Dec;5(6):1425-9. doi: 10.3892/or.5.6.1425. PMID: 9769381

Prognosis

Differential expression of preferentially expressed antigen in melanoma (PRAME) in testicular germ cell tumors - A comparative study with SOX17.
Zhou Y, Rothrock A, Murugan P, Li F, Bu L
Exp Mol Pathol 2022 Jun;126:104761. Epub 2022 Apr 4 doi: 10.1016/j.yexmp.2022.104761. PMID: 35390309
Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists.
Lobo J, Costa AL, Vilela-Salgueiro B, Rodrigues Â, Guimarães R, Cantante M, Lopes P, Antunes L, Jerónimo C, Henrique R
Hum Pathol 2018 Dec;82:113-124. Epub 2018 Jul 21 doi: 10.1016/j.humpath.2018.07.016. PMID: 30041024
Detailed pathologic analysis on the co-occurrence of non-seminomatous germ cell tumor subtypes in matched orchiectomy and retroperitoneal lymph node dissections.
Spratt DE, Suresh K, Osawa T, Schipper M, Jackson WC, Abugharib A, Lebastchi A, Smith D, Montgomery JS, Palapattu GS, Priya Kunju L, Wu A, Lew M, Tomlins SA, Chinnaiyan AM, Weizer AZ, Hafez KS, Kaffenberger SD, Udager A, Mehra R
Med Oncol 2018 Jan 31;35(3):21. doi: 10.1007/s12032-018-1090-y. PMID: 29387987
Robot-assisted retroperitoneal lymph node dissection (RA-RPLND) in the adolescent population.
Glaser AP, Bowen DK, Lindgren BW, Meeks JJ
J Pediatr Urol 2017 Apr;13(2):223-224. Epub 2017 Feb 17 doi: 10.1016/j.jpurol.2017.01.007. PMID: 28262537
Clinical use of serum TRA-1-60 as tumor marker in patients with germ cell cancer.
Lajer H, Daugaard G, Andersson AM, Skakkebaek NE
Int J Cancer 2002 Jul 10;100(2):244-6. doi: 10.1002/ijc.10459. PMID: 12115576

Clinical prediction guides

Differential expression of preferentially expressed antigen in melanoma (PRAME) in testicular germ cell tumors - A comparative study with SOX17.
Zhou Y, Rothrock A, Murugan P, Li F, Bu L
Exp Mol Pathol 2022 Jun;126:104761. Epub 2022 Apr 4 doi: 10.1016/j.yexmp.2022.104761. PMID: 35390309
Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists.
Lobo J, Costa AL, Vilela-Salgueiro B, Rodrigues Â, Guimarães R, Cantante M, Lopes P, Antunes L, Jerónimo C, Henrique R
Hum Pathol 2018 Dec;82:113-124. Epub 2018 Jul 21 doi: 10.1016/j.humpath.2018.07.016. PMID: 30041024
Detailed pathologic analysis on the co-occurrence of non-seminomatous germ cell tumor subtypes in matched orchiectomy and retroperitoneal lymph node dissections.
Spratt DE, Suresh K, Osawa T, Schipper M, Jackson WC, Abugharib A, Lebastchi A, Smith D, Montgomery JS, Palapattu GS, Priya Kunju L, Wu A, Lew M, Tomlins SA, Chinnaiyan AM, Weizer AZ, Hafez KS, Kaffenberger SD, Udager A, Mehra R
Med Oncol 2018 Jan 31;35(3):21. doi: 10.1007/s12032-018-1090-y. PMID: 29387987
Brain metastasis from non-seminomatous germ cell tumors of the testis: indications for aggressive treatment.
Salvati M, Piccirilli M, Raco A, Santoro A, Frati R, Lenzi J, Lanzetta G, Agrillo A, Frati A
Neurosurg Rev 2006 Apr;29(2):130-7. Epub 2005 Nov 23 doi: 10.1007/s10143-005-0004-6. PMID: 16328533
Morphology of testicular parenchyma adjacent to germ cell tumours. An interim report.
Oosterhuis JW, Kersemaekers AM, Jacobsen GK, Timmer A, Steyerberg EW, Molier M, Van Weeren PC, Stoop H, Looijenga LH
APMIS 2003 Jan;111(1):32-40; discussion 41-2. doi: 10.1034/j.1600-0463.2003.11101061.x. PMID: 12752231

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