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HIV-associated nephropathy

MedGen UID:
37145
•Concept ID:
C0078911
•
Disease or Syndrome
Synonyms: AIDS Associated Nephropathies; AIDS Associated Nephropathy; AIDS Nephropathies; AIDS Nephropathy; AIDS-Associated Nephropathies; AIDS-Associated Nephropathy; HIV Associated Nephropathies; HIV Associated Nephropathy; HIV Related Nephropathies; HIV Related Nephropathy; HIV-Associated Nephropathies; HIV-Associated Nephropathy; HIV-Related Nephropathies; HIV-Related Nephropathy; Human Immunodeficiency Virus Associated Nephropathy; Human Immunodeficiency Virus-Associated Nephropathy; Nephropathies, AIDS; Nephropathies, AIDS Associated; Nephropathies, AIDS-Associated; Nephropathies, HIV Associated; Nephropathies, HIV Related; Nephropathies, HIV-Associated; Nephropathies, HIV-Related; Nephropathy, AIDS; Nephropathy, AIDS Associated; Nephropathy, AIDS-Associated; Nephropathy, HIV Associated; Nephropathy, HIV Related; Nephropathy, HIV-Associated; Nephropathy, HIV-Related
SNOMED CT: Acquired immune deficiency syndrome-related nephropathy (236406007); AIDS - Acquired immune deficiency synd-related nephropathy (236406007)
 
Monarch Initiative: MONDO:0005798

Definition

Renal disease in human immunodeficiency virus (HIV)-infected patients. It is characterized by nephrotic syndrome, azotemia, normal to large kidneys on ultrasound images, and focal segmental glomerulosclerosis on renal biopsy findings. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHIV-associated nephropathy

Professional guidelines

PubMed

HIV at 40: kidney disease in HIV treatment, prevention, and cure.
Lucas A, Wyatt CM
Kidney Int 2022 Oct;102(4):740-749. Epub 2022 Jul 16 doi: 10.1016/j.kint.2022.06.021. PMID: 35850290Free PMC Article
Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
Pharmacotherapy and treatment options for HIV-associated nephropathy.
Menez S, Hanouneh M, McMahon BA, Fine DM, Atta MG
Expert Opin Pharmacother 2018 Jan;19(1):39-48. Epub 2017 Dec 26 doi: 10.1080/14656566.2017.1416099. PMID: 29224373Free PMC Article

Recent clinical studies

Etiology

Childhood HIV-associated nephropathy: 36 years later.
Ray PE, Li J, Das JR, Tang P
Pediatr Nephrol 2021 Aug;36(8):2189-2201. Epub 2020 Oct 12 doi: 10.1007/s00467-020-04756-4. PMID: 33044676Free PMC Article
APOL1 Nephropathy: From Genetics to Clinical Applications.
Friedman DJ, Pollak MR
Clin J Am Soc Nephrol 2021 Feb 8;16(2):294-303. Epub 2020 Jul 2 doi: 10.2215/CJN.15161219. PMID: 32616495Free PMC Article
Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
Pharmacotherapy and treatment options for HIV-associated nephropathy.
Menez S, Hanouneh M, McMahon BA, Fine DM, Atta MG
Expert Opin Pharmacother 2018 Jan;19(1):39-48. Epub 2017 Dec 26 doi: 10.1080/14656566.2017.1416099. PMID: 29224373Free PMC Article
HIV-associated nephropathy: pathogenesis.
Medapalli RK, He JC, Klotman PE
Curr Opin Nephrol Hypertens 2011 May;20(3):306-11. doi: 10.1097/MNH.0b013e328345359a. PMID: 21358326Free PMC Article

Diagnosis

HIV Associated Nephropathy.
Alebiosu CO
West Afr J Med 2021 Apr 23;38(4):300-301. PMID: 33900703
Childhood HIV-associated nephropathy: 36 years later.
Ray PE, Li J, Das JR, Tang P
Pediatr Nephrol 2021 Aug;36(8):2189-2201. Epub 2020 Oct 12 doi: 10.1007/s00467-020-04756-4. PMID: 33044676Free PMC Article
Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
Pharmacotherapy and treatment options for HIV-associated nephropathy.
Menez S, Hanouneh M, McMahon BA, Fine DM, Atta MG
Expert Opin Pharmacother 2018 Jan;19(1):39-48. Epub 2017 Dec 26 doi: 10.1080/14656566.2017.1416099. PMID: 29224373Free PMC Article
HIV-associated nephropathy.
Ross MJ, Klotman PE
AIDS 2004 May 21;18(8):1089-99. doi: 10.1097/00002030-200405210-00002. PMID: 15166524

Therapy

Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
Pharmacotherapy and treatment options for HIV-associated nephropathy.
Menez S, Hanouneh M, McMahon BA, Fine DM, Atta MG
Expert Opin Pharmacother 2018 Jan;19(1):39-48. Epub 2017 Dec 26 doi: 10.1080/14656566.2017.1416099. PMID: 29224373Free PMC Article
Predictors of HIV-associated nephropathy.
Waheed S, Atta MG
Expert Rev Anti Infect Ther 2014 May;12(5):555-63. Epub 2014 Mar 21 doi: 10.1586/14787210.2014.901170. PMID: 24655211
HIV-associated nephropathy.
Khan S, Haragsim L, Laszik ZG
Adv Chronic Kidney Dis 2006 Jul;13(3):307-13. doi: 10.1053/j.ackd.2006.04.013. PMID: 16815235
HIV-associated nephropathy.
Ross MJ, Klotman PE
AIDS 2004 May 21;18(8):1089-99. doi: 10.1097/00002030-200405210-00002. PMID: 15166524

Prognosis

Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
Predictors of HIV-associated nephropathy.
Waheed S, Atta MG
Expert Rev Anti Infect Ther 2014 May;12(5):555-63. Epub 2014 Mar 21 doi: 10.1586/14787210.2014.901170. PMID: 24655211
HIV-associated nephropathy.
Khan S, Haragsim L, Laszik ZG
Adv Chronic Kidney Dis 2006 Jul;13(3):307-13. doi: 10.1053/j.ackd.2006.04.013. PMID: 16815235
HIV-associated nephropathy.
Ross MJ, Klotman PE
AIDS 2004 May 21;18(8):1089-99. doi: 10.1097/00002030-200405210-00002. PMID: 15166524
Collapsing glomerulopathy.
Schwimmer JA, Markowitz GS, Valeri A, Appel GB
Semin Nephrol 2003 Mar;23(2):209-18. doi: 10.1053/snep.2003.50019. PMID: 12704581

Clinical prediction guides

Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
Predictors of HIV-associated nephropathy.
Waheed S, Atta MG
Expert Rev Anti Infect Ther 2014 May;12(5):555-63. Epub 2014 Mar 21 doi: 10.1586/14787210.2014.901170. PMID: 24655211
Interventions for HIV-associated nephropathy.
Yahaya I, Uthman OA, Uthman MM
Cochrane Database Syst Rev 2013 Jan 31;2013(1):CD007183. doi: 10.1002/14651858.CD007183.pub3. PMID: 23440812Free PMC Article
APOL1 and kidney disease.
Pollak MR, Genovese G, Friedman DJ
Curr Opin Nephrol Hypertens 2012 Mar;21(2):179-82. doi: 10.1097/MNH.0b013e32835012ab. PMID: 22257798
HIV-associated nephropathy: clinical presentation, pathology, and epidemiology in the era of antiretroviral therapy.
Wyatt CM, Klotman PE, D'Agati VD
Semin Nephrol 2008 Nov;28(6):513-22. doi: 10.1016/j.semnephrol.2008.08.005. PMID: 19013322Free PMC Article

Recent systematic reviews

MicroRNAs Associated with Chronic Kidney Disease in the General Population and High-Risk Subgroups-A Systematic Review.
Motshwari DD, Matshazi DM, Erasmus RT, Kengne AP, Matsha TE, George C
Int J Mol Sci 2023 Jan 16;24(2) doi: 10.3390/ijms24021792. PMID: 36675311Free PMC Article
Apolipoprotein L1 gene variants and kidney disease in patients with HIV: a systematic review and meta-analysis.
Waziri B, Raji YE, Ekrikpo UE, Naicker S
J Nephrol 2023 May;36(4):1119-1134. Epub 2022 Dec 13 doi: 10.1007/s40620-022-01512-9. PMID: 36510118
Impact of Antiretroviral Therapy on Kidney Disease in HIV Infected Individuals - A Qualitative Systematic Review.
Adnani H, Agrawal N, Khatri A, Vialet J, Zhang M, Cervia J
J Int Assoc Provid AIDS Care 2022 Jan-Dec;21:23259582221089194. doi: 10.1177/23259582221089194. PMID: 35369795Free PMC Article
Interventions for HIV-associated nephropathy.
Yahaya I, Uthman OA, Uthman MM
Cochrane Database Syst Rev 2013 Jan 31;2013(1):CD007183. doi: 10.1002/14651858.CD007183.pub3. PMID: 23440812Free PMC Article
Interventions for HIV-associated nephropathy.
Yahaya I, Uthman AO, Uthman MM
Cochrane Database Syst Rev 2009 Oct 7;(4):CD007183. doi: 10.1002/14651858.CD007183.pub2. PMID: 19821397

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